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Items: 1 to 50 of 51

1.

Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks.

Galligan JJ, Wepy JA, Streeter MD, Kingsley PJ, Mitchener MM, Wauchope OR, Beavers WN, Rose KL, Wang T, Spiegel DA, Marnett LJ.

Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9228-9233. doi: 10.1073/pnas.1802901115. Epub 2018 Aug 27.

2.

Detection of Cyclooxygenase-2-Derived Oxygenation Products of the Endogenous Cannabinoid 2-Arachidonoylglycerol in Mouse Brain.

Morgan AJ, Kingsley PJ, Mitchener MM, Altemus M, Patrick TA, Gaulden AD, Marnett LJ, Patel S.

ACS Chem Neurosci. 2018 Jul 18;9(7):1552-1559. doi: 10.1021/acschemneuro.7b00499. Epub 2018 May 9.

3.

Therapeutic endocannabinoid augmentation for mood and anxiety disorders: comparative profiling of FAAH, MAGL and dual inhibitors.

Bedse G, Bluett RJ, Patrick TA, Romness NK, Gaulden AD, Kingsley PJ, Plath N, Marnett LJ, Patel S.

Transl Psychiatry. 2018 Apr 26;8(1):92. doi: 10.1038/s41398-018-0141-7.

4.

Oxidative stress increases M1dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA.

Wauchope OR, Mitchener MM, Beavers WN, Galligan JJ, Camarillo JM, Sanders WD, Kingsley PJ, Shim HN, Blackwell T, Luong T, deCaestecker M, Fessel JP, Marnett LJ.

Nucleic Acids Res. 2018 Apr 20;46(7):3458-3467. doi: 10.1093/nar/gky089.

5.

Functional Redundancy Between Canonical Endocannabinoid Signaling Systems in the Modulation of Anxiety.

Bedse G, Hartley ND, Neale E, Gaulden AD, Patrick TA, Kingsley PJ, Uddin MJ, Plath N, Marnett LJ, Patel S.

Biol Psychiatry. 2017 Oct 1;82(7):488-499. doi: 10.1016/j.biopsych.2017.03.002. Epub 2017 Mar 15.

PMID:
28438413
6.

Quantitative Analysis and Discovery of Lysine and Arginine Modifications.

Galligan JJ, Kingsley PJ, Wauchope OR, Mitchener MM, Camarillo JM, Wepy JA, Harris PS, Fritz KS, Marnett LJ.

Anal Chem. 2017 Jan 17;89(2):1299-1306. doi: 10.1021/acs.analchem.6b04105. Epub 2016 Dec 30.

7.

Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors.

Uddin MJ, Crews BC, Xu S, Ghebreselasie K, Daniel CK, Kingsley PJ, Banerjee S, Marnett LJ.

ACS Chem Biol. 2016 Nov 18;11(11):3052-3060. Epub 2016 Sep 19.

8.

Assay of Endocannabinoid Oxidation by Cyclooxygenase-2.

Kudalkar SN, Kingsley PJ, Marnett LJ.

Methods Mol Biol. 2016;1412:205-15. doi: 10.1007/978-1-4939-3539-0_21.

9.

Fluorocoxib A loaded nanoparticles enable targeted visualization of cyclooxygenase-2 in inflammation and cancer.

Uddin MJ, Werfel TA, Crews BC, Gupta MK, Kavanaugh TE, Kingsley PJ, Boyd K, Marnett LJ, Duvall CL.

Biomaterials. 2016 Jun;92:71-80. doi: 10.1016/j.biomaterials.2016.03.028. Epub 2016 Mar 21.

10.

Cox-2-derived PGE2 induces Id1-dependent radiation resistance and self-renewal in experimental glioblastoma.

Cook PJ, Thomas R, Kingsley PJ, Shimizu F, Montrose DC, Marnett LJ, Tabar VS, Dannenberg AJ, Benezra R.

Neuro Oncol. 2016 Oct;18(10):1379-89. doi: 10.1093/neuonc/now049. Epub 2016 Mar 28.

11.

Nuclear Oxidation of a Major Peroxidation DNA Adduct, M1dG, in the Genome.

Wauchope OR, Beavers WN, Galligan JJ, Mitchener MM, Kingsley PJ, Marnett LJ.

Chem Res Toxicol. 2015 Dec 21;28(12):2334-42. doi: 10.1021/acs.chemrestox.5b00340. Epub 2015 Nov 11.

12.

Multitargeting of selected prostanoid receptors provides agents with enhanced anti-inflammatory activity in macrophages.

Wang JW, Woodward DF, Martos JL, Cornell CL, Carling RW, Kingsley PJ, Marnett LJ.

FASEB J. 2016 Jan;30(1):394-404. doi: 10.1096/fj.15-275610. Epub 2015 Sep 29.

PMID:
26420849
13.

Targeted imaging of cancer by fluorocoxib C, a near-infrared cyclooxygenase-2 probe.

Uddin MJ, Crews BC, Ghebreselasie K, Daniel CK, Kingsley PJ, Xu S, Marnett LJ.

J Biomed Opt. 2015 May;20(5):50502. doi: 10.1117/1.JBO.20.5.050502.

14.

13-Methylarachidonic acid is a positive allosteric modulator of endocannabinoid oxygenation by cyclooxygenase.

Kudalkar SN, Nikas SP, Kingsley PJ, Xu S, Galligan JJ, Rouzer CA, Banerjee S, Ji L, Eno MR, Makriyannis A, Marnett LJ.

J Biol Chem. 2015 Mar 20;290(12):7897-909. doi: 10.1074/jbc.M114.634014. Epub 2015 Feb 2.

15.

Genetic disruption of 2-arachidonoylglycerol synthesis reveals a key role for endocannabinoid signaling in anxiety modulation.

Shonesy BC, Bluett RJ, Ramikie TS, Báldi R, Hermanson DJ, Kingsley PJ, Marnett LJ, Winder DG, Colbran RJ, Patel S.

Cell Rep. 2014 Dec 11;9(5):1644-1653. doi: 10.1016/j.celrep.2014.11.001. Epub 2014 Nov 26.

16.

Protein modification by adenine propenal.

Shuck SC, Wauchope OR, Rose KL, Kingsley PJ, Rouzer CA, Shell SM, Sugitani N, Chazin WJ, Zagol-Ikapitte I, Boutaud O, Oates JA, Galligan JJ, Beavers WN, Marnett LJ.

Chem Res Toxicol. 2014 Oct 20;27(10):1732-42. doi: 10.1021/tx500218g. Epub 2014 Sep 24.

17.

Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation.

Hermanson DJ, Hartley ND, Gamble-George J, Brown N, Shonesy BC, Kingsley PJ, Colbran RJ, Reese J, Marnett LJ, Patel S.

Nat Neurosci. 2013 Sep;16(9):1291-8. doi: 10.1038/nn.3480. Epub 2013 Aug 4.

18.

Effect of zileuton and celecoxib on urinary LTE4 and PGE-M levels in smokers.

Mohebati A, Milne GL, Zhou XK, Duffield-Lillico AJ, Boyle JO, Knutson A, Bosworth BP, Kingsley PJ, Marnett LJ, Brown PH, Akpa EG, Szabo E, Dannenberg AJ.

Cancer Prev Res (Phila). 2013 Jul;6(7):646-55. doi: 10.1158/1940-6207.CAPR-13-0083. Epub 2013 May 16.

19.

Cannabinoid receptor 1 suppresses transient receptor potential vanilloid 1-induced inflammatory responses to corneal injury.

Yang Y, Yang H, Wang Z, Varadaraj K, Kumari SS, Mergler S, Okada Y, Saika S, Kingsley PJ, Marnett LJ, Reinach PS.

Cell Signal. 2013 Feb;25(2):501-11. doi: 10.1016/j.cellsig.2012.10.015. Epub 2012 Nov 8.

20.

Substrate-Selective Inhibition of Cyclooxygenase-2: Development and Evaluation of Achiral Profen Probes.

Windsor MA, Hermanson DJ, Kingsley PJ, Xu S, Crews BC, Ho W, Keenan CM, Banerjee S, Sharkey KA, Marnett LJ.

ACS Med Chem Lett. 2012 Sep 13;3(9):759-763. Epub 2012 Aug 15.

21.

Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold.

Liedtke AJ, Crews BC, Daniel CM, Blobaum AL, Kingsley PJ, Ghebreselasie K, Marnett LJ.

J Med Chem. 2012 Mar 8;55(5):2287-300. doi: 10.1021/jm201528b. Epub 2012 Feb 14.

22.

Selection of monoclonal antibodies against 6-oxo-M(1)dG and their use in an LC-MS/MS assay for the presence of 6-oxo-M(1)dG in vivo.

Akingbade D, Kingsley PJ, Shuck SC, Cooper T, Carnahan R, Szekely J, Marnett LJ.

Chem Res Toxicol. 2012 Feb 20;25(2):454-61. doi: 10.1021/tx200494h. Epub 2012 Jan 24.

23.

Fluorinated COX-2 inhibitors as agents in PET imaging of inflammation and cancer.

Uddin MJ, Crews BC, Ghebreselasie K, Huda I, Kingsley PJ, Ansari MS, Tantawy MN, Reese J, Marnett LJ.

Cancer Prev Res (Phila). 2011 Oct;4(10):1536-45. doi: 10.1158/1940-6207.CAPR-11-0120. Epub 2011 Sep 7.

24.

The role of NAG-1/GDF15 in the inhibition of intestinal polyps in APC/Min mice by sulindac.

Wang X, Kingsley PJ, Marnett LJ, Eling TE.

Cancer Prev Res (Phila). 2011 Jan;4(1):150-60. doi: 10.1158/1940-6207.CAPR-10-0196.

25.
26.

Selective visualization of cyclooxygenase-2 in inflammation and cancer by targeted fluorescent imaging agents.

Uddin MJ, Crews BC, Blobaum AL, Kingsley PJ, Gorden DL, McIntyre JO, Matrisian LM, Subbaramaiah K, Dannenberg AJ, Piston DW, Marnett LJ.

Cancer Res. 2010 May 1;70(9):3618-27. doi: 10.1158/0008-5472.CAN-09-2664.

27.
28.

Repeated homotypic stress elevates 2-arachidonoylglycerol levels and enhances short-term endocannabinoid signaling at inhibitory synapses in basolateral amygdala.

Patel S, Kingsley PJ, Mackie K, Marnett LJ, Winder DG.

Neuropsychopharmacology. 2009 Dec;34(13):2699-709. doi: 10.1038/npp.2009.101. Epub 2009 Aug 12.

29.

Analysis of endocannabinoids, their congeners and COX-2 metabolites.

Kingsley PJ, Marnett LJ.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Sep 15;877(26):2746-54. doi: 10.1016/j.jchromb.2009.05.024. Epub 2009 May 21. Review.

30.

The influence of double bond geometry in the inhibition of cyclooxygenases by sulindac derivatives.

Walters MJ, Blobaum AL, Kingsley PJ, Felts AS, Sulikowski GA, Marnett LJ.

Bioorg Med Chem Lett. 2009 Jun 15;19(12):3271-4. doi: 10.1016/j.bmcl.2009.04.078. Epub 2009 Apr 23.

31.

Genetic loss of Faah compromises male fertility in mice.

Sun X, Wang H, Okabe M, Mackie K, Kingsley PJ, Marnett LJ, Cravatt BF, Dey SK.

Biol Reprod. 2009 Feb;80(2):235-42. doi: 10.1095/biolreprod.108.072736. Epub 2008 Nov 5.

32.

NMDA-induced seizure intensity is enhanced in COX-2 deficient mice.

Toscano CD, Kingsley PJ, Marnett LJ, Bosetti F.

Neurotoxicology. 2008 Nov;29(6):1114-20. doi: 10.1016/j.neuro.2008.08.008. Epub 2008 Sep 11.

33.

Oxidative metabolism of a fatty acid amide hydrolase-regulated lipid, arachidonoyltaurine.

Turman MV, Kingsley PJ, Rouzer CA, Cravatt BF, Marnett LJ.

Biochemistry. 2008 Mar 25;47(12):3917-25. doi: 10.1021/bi702530z. Epub 2008 Mar 1.

34.

LC-MS-MS analysis of neutral eicosanoids.

Kingsley PJ, Marnett LJ.

Methods Enzymol. 2007;433:91-112.

PMID:
17954230
35.

Induction and function of lipocalin prostaglandin D synthase in host immunity.

Joo M, Kwon M, Sadikot RT, Kingsley PJ, Marnett LJ, Blackwell TS, Peebles RS Jr, Urade Y, Christman JW.

J Immunol. 2007 Aug 15;179(4):2565-75.

36.

Desmethyl derivatives of indomethacin and sulindac as probes for cyclooxygenase-dependent biology.

Felts AS, Ji C, Stafford JB, Crews BC, Kingsley PJ, Rouzer CA, Washington MK, Subbaramaiah K, Siegel BS, Young SM, Dannenberg AJ, Marnett LJ.

ACS Chem Biol. 2007 Jul 20;2(7):479-83. Epub 2007 Jun 29.

PMID:
17602619
37.

Differential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation.

Wang H, Xie H, Sun X, Kingsley PJ, Marnett LJ, Cravatt BF, Dey SK.

Prostaglandins Other Lipid Mediat. 2007 Feb;83(1-2):62-74. Epub 2006 Nov 28.

38.

Fatty acid amide hydrolase deficiency limits early pregnancy events.

Wang H, Xie H, Guo Y, Zhang H, Takahashi T, Kingsley PJ, Marnett LJ, Das SK, Cravatt BF, Dey SK.

J Clin Invest. 2006 Aug;116(8):2122-31.

39.

Identification and functional characterization of brainstem cannabinoid CB2 receptors.

Van Sickle MD, Duncan M, Kingsley PJ, Mouihate A, Urbani P, Mackie K, Stella N, Makriyannis A, Piomelli D, Davison JS, Marnett LJ, Di Marzo V, Pittman QJ, Patel KD, Sharkey KA.

Science. 2005 Oct 14;310(5746):329-32.

40.

Simultaneous analysis of prostaglandin glyceryl esters and prostaglandins by electrospray tandem mass spectrometry.

Kingsley PJ, Rouzer CA, Saleh S, Marnett LJ.

Anal Biochem. 2005 Aug 15;343(2):203-11.

PMID:
16004953
41.

N-acylphosphatidylethanolamine-hydrolyzing phospholipase D is an important determinant of uterine anandamide levels during implantation.

Guo Y, Wang H, Okamoto Y, Ueda N, Kingsley PJ, Marnett LJ, Schmid HH, Das SK, Dey SK.

J Biol Chem. 2005 Jun 24;280(25):23429-32. Epub 2005 May 12.

42.

RAW264.7 cells lack prostaglandin-dependent autoregulation of tumor necrosis factor-alpha secretion.

Rouzer CA, Jacobs AT, Nirodi CS, Kingsley PJ, Morrow JD, Marnett LJ.

J Lipid Res. 2005 May;46(5):1027-37. Epub 2005 Feb 1.

43.

Aberrant cannabinoid signaling impairs oviductal transport of embryos.

Wang H, Guo Y, Wang D, Kingsley PJ, Marnett LJ, Das SK, DuBois RN, Dey SK.

Nat Med. 2004 Oct;10(10):1074-80. Epub 2004 Sep 19. Erratum in: Nat Med. 2004 Dec;10(12):1397.

PMID:
15378054
44.

Cyclooxygenase-1-dependent prostaglandin synthesis modulates tumor necrosis factor-alpha secretion in lipopolysaccharide-challenged murine resident peritoneal macrophages.

Rouzer CA, Kingsley PJ, Wang H, Zhang H, Morrow JD, Dey SK, Marnett LJ.

J Biol Chem. 2004 Aug 13;279(33):34256-68. Epub 2004 Jun 4.

45.

Analysis of endocannabinoids by Ag+ coordination tandem mass spectrometry.

Kingsley PJ, Marnett LJ.

Anal Biochem. 2003 Mar 1;314(1):8-15.

PMID:
12633597
46.

Selective oxygenation of N-arachidonylglycine by cyclooxygenase-2.

Prusakiewicz JJ, Kingsley PJ, Kozak KR, Marnett LJ.

Biochem Biophys Res Commun. 2002 Aug 23;296(3):612-7.

PMID:
12176025
47.

A case of intrinsic asthma.

Kingsley PJ.

Br Med J. 1977 Sep 10;2(6088):701. No abstract available.

48.

Letter: Oral sodium cromoglycate in gastrointestinal allergy.

Kingsley PJ.

Lancet. 1974 Oct 26;2(7887):1011. No abstract available.

PMID:
4138357
49.

A comparison of the beta 1 and beta 2 effects of subcutaneous isoprenaline, sulbutamol and terbutaline in adult man.

Kingsley PJ, Volans GN.

Eur J Clin Pharmacol. 1974 Jul 26;7(4):263-8. No abstract available.

PMID:
4850180
50.

Class experiment in clinical pharmacology with benzilonium bromide, an anticholinergic drug.

Kingsley PJ, Turner P.

Eur J Clin Pharmacol. 1974;7(2):141-3. No abstract available.

PMID:
4851039

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