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Items: 1 to 50 of 116


Laser-based 3D bioprinting for spatial and size control of tumor spheroids and embryoid bodies.

Kingsley DM, Roberge CL, Rudkouskaya A, Faulkner DE, Barroso M, Intes X, Corr DT.

Acta Biomater. 2019 Feb 15. pii: S1742-7061(19)30118-7. doi: 10.1016/j.actbio.2019.02.014. [Epub ahead of print]


Multi-modal characterization of polymeric gels to determine the influence of testing method on observed elastic modulus.

Kingsley DM, McCleery CH, Johnson CDL, Bramson MTK, Rende D, Gilbert RJ, Corr DT.

J Mech Behav Biomed Mater. 2019 Apr;92:152-161. doi: 10.1016/j.jmbbm.2019.01.003. Epub 2019 Jan 10.


DNA fragility in the parallel evolution of pelvic reduction in stickleback fish.

Xie KT, Wang G, Thompson AC, Wucherpfennig JI, Reimchen TE, MacColl ADC, Schluter D, Bell MA, Vasquez KM, Kingsley DM.

Science. 2019 Jan 4;363(6422):81-84. doi: 10.1126/science.aan1425. Epub 2019 Jan 3.


A novel enhancer near the Pitx1 gene influences development and evolution of pelvic appendages in vertebrates.

Thompson AC, Capellini TD, Guenther CA, Chan YF, Infante CR, Menke DB, Kingsley DM.

Elife. 2018 Nov 30;7. pii: e38555. doi: 10.7554/eLife.38555.


Characterization of a Human-Specific Tandem Repeat Associated with Bipolar Disorder and Schizophrenia.

Song JHT, Lowe CB, Kingsley DM.

Am J Hum Genet. 2018 Sep 6;103(3):421-430. doi: 10.1016/j.ajhg.2018.07.011. Epub 2018 Aug 9.


Experimental evidence for rapid genomic adaptation to a new niche in an adaptive radiation.

Marques DA, Jones FC, Di Palma F, Kingsley DM, Reimchen TE.

Nat Ecol Evol. 2018 Jul;2(7):1128-1138. doi: 10.1038/s41559-018-0581-8. Epub 2018 Jun 25.


Corrigendum: Detecting differential copy number variation between groups of samples.

Lowe CB, Sanchez-Luege N, Howes TR, Brady SD, Daugherty RR, Jones FC, Bell MA, Kingsley DM.

Genome Res. 2018 May;28(5):766.1. doi: 10.1101/gr.237370.118. No abstract available.


Detecting differential copy number variation between groups of samples.

Lowe CB, Sanchez-Luege N, Howes TR, Brady SD, Daugherty RR, Jones FC, Bell MA, Kingsley DM.

Genome Res. 2018 Feb;28(2):256-265. doi: 10.1101/gr.206938.116. Epub 2017 Dec 11. Erratum in: Genome Res. 2018 May;28(5):766.1.


Dorsal spine evolution in threespine sticklebacks via a splicing change in MSX2A.

Howes TR, Summers BR, Kingsley DM.

BMC Biol. 2017 Dec 7;15(1):115. doi: 10.1186/s12915-017-0456-5.


Beautiful Piles of Bones: An Interview with 2017 Genetics Society of America Medal Recipient David M. Kingsley.

Kingsley DM.

Genetics. 2017 Dec;207(4):1221-1222. doi: 10.1534/genetics.117.300415.


An Unexpectedly Complex Architecture for Skin Pigmentation in Africans.

Martin AR, Lin M, Granka JM, Myrick JW, Liu X, Sockell A, Atkinson EG, Werely CJ, Möller M, Sandhu MS, Kingsley DM, Hoal EG, Liu X, Daly MJ, Feldman MW, Gignoux CR, Bustamante CD, Henn BM.

Cell. 2017 Nov 30;171(6):1340-1353.e14. doi: 10.1016/j.cell.2017.11.015.


Genetic Coupling of Female Mate Choice with Polygenic Ecological Divergence Facilitates Stickleback Speciation.

Bay RA, Arnegard ME, Conte GL, Best J, Bedford NL, McCann SR, Dubin ME, Chan YF, Jones FC, Kingsley DM, Schluter D, Peichel CL.

Curr Biol. 2017 Nov 6;27(21):3344-3349.e4. doi: 10.1016/j.cub.2017.09.037. Epub 2017 Oct 19.


Genomic dissection of conserved transcriptional regulation in intestinal epithelial cells.

Lickwar CR, Camp JG, Weiser M, Cocchiaro JL, Kingsley DM, Furey TS, Sheikh SZ, Rawls JF.

PLoS Biol. 2017 Aug 29;15(8):e2002054. doi: 10.1371/journal.pbio.2002054. eCollection 2017 Aug.


Ancient selection for derived alleles at a GDF5 enhancer influencing human growth and osteoarthritis risk.

Capellini TD, Chen H, Cao J, Doxey AC, Kiapour AM, Schoor M, Kingsley DM.

Nat Genet. 2017 Aug;49(8):1202-1210. doi: 10.1038/ng.3911. Epub 2017 Jul 3.


Convergent evolution of SWS2 opsin facilitates adaptive radiation of threespine stickleback into different light environments.

Marques DA, Taylor JS, Jones FC, Di Palma F, Kingsley DM, Reimchen TE.

PLoS Biol. 2017 Apr 11;15(4):e2001627. doi: 10.1371/journal.pbio.2001627. eCollection 2017 Apr.


Heads, Shoulders, Elbows, Knees, and Toes: Modular Gdf5 Enhancers Control Different Joints in the Vertebrate Skeleton.

Chen H, Capellini TD, Schoor M, Mortlock DP, Reddi AH, Kingsley DM.

PLoS Genet. 2016 Nov 30;12(11):e1006454. doi: 10.1371/journal.pgen.1006454. eCollection 2016 Nov.


Three cheers for the three-spined stickleback.

Heng K, Thompson A, Chu D, Kingsley DM.

Lab Anim (NY). 2016 Oct 20;45(11):421. doi: 10.1038/laban.1142. No abstract available.


Microcapsules and 3D customizable shelled microenvironments from laser direct-written microbeads.

Kingsley DM, Dias AD, Corr DT.

Biotechnol Bioeng. 2016 Oct;113(10):2264-74. doi: 10.1002/bit.25987. Epub 2016 Aug 9.


Evolving New Skeletal Traits by cis-Regulatory Changes in Bone Morphogenetic Proteins.

Indjeian VB, Kingman GA, Jones FC, Guenther CA, Grimwood J, Schmutz J, Myers RM, Kingsley DM.

Cell. 2016 Jan 14;164(1-2):45-56. doi: 10.1016/j.cell.2015.12.007. Epub 2016 Jan 7.


Extent of QTL Reuse During Repeated Phenotypic Divergence of Sympatric Threespine Stickleback.

Conte GL, Arnegard ME, Best J, Chan YF, Jones FC, Kingsley DM, Schluter D, Peichel CL.

Genetics. 2015 Nov;201(3):1189-200. doi: 10.1534/genetics.115.182550. Epub 2015 Sep 16.


A distinct regulatory region of the Bmp5 locus activates gene expression following adult bone fracture or soft tissue injury.

Guenther CA, Wang Z, Li E, Tran MC, Logan CY, Nusse R, Pantalena-Filho L, Yang GP, Kingsley DM.

Bone. 2015 Aug;77:31-41. doi: 10.1016/j.bone.2015.04.010. Epub 2015 Apr 14.


A recurrent regulatory change underlying altered expression and Wnt response of the stickleback armor plates gene EDA.

O'Brown NM, Summers BR, Jones FC, Brady SD, Kingsley DM.

Elife. 2015 Jan 28;4:e05290. doi: 10.7554/eLife.05290.


Recent advances in bioprinting and applications for biosensing.

Dias AD, Kingsley DM, Corr DT.

Biosensors (Basel). 2014 Apr 24;4(2):111-36. doi: 10.3390/bios4020111. eCollection 2014 Jun. Review.


Mesenchymal cells. Defining a mesenchymal progenitor niche at single-cell resolution.

Kumar ME, Bogard PE, Espinoza FH, Menke DB, Kingsley DM, Krasnow MA.

Science. 2014 Nov 14;346(6211):1258810. doi: 10.1126/science.1258810.


The phosphate exporter xpr1b is required for differentiation of tissue-resident macrophages.

Meireles AM, Shiau CE, Guenther CA, Sidik H, Kingsley DM, Talbot WS.

Cell Rep. 2014 Sep 25;8(6):1659-1667. doi: 10.1016/j.celrep.2014.08.018. Epub 2014 Sep 15.


Evolved tooth gain in sticklebacks is associated with a cis-regulatory allele of Bmp6.

Cleves PA, Ellis NA, Jimenez MT, Nunez SM, Schluter D, Kingsley DM, Miller CT.

Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13912-7. doi: 10.1073/pnas.1407567111. Epub 2014 Sep 9.


Genetics of ecological divergence during speciation.

Arnegard ME, McGee MD, Matthews B, Marchinko KB, Conte GL, Kabir S, Bedford N, Bergek S, Chan YF, Jones FC, Kingsley DM, Peichel CL, Schluter D.

Nature. 2014 Jul 17;511(7509):307-11. doi: 10.1038/nature13301. Epub 2014 Jun 8.


A molecular basis for classic blond hair color in Europeans.

Guenther CA, Tasic B, Luo L, Bedell MA, Kingsley DM.

Nat Genet. 2014 Jul;46(7):748-52. doi: 10.1038/ng.2991. Epub 2014 Jun 1.


Modular skeletal evolution in sticklebacks is controlled by additive and clustered quantitative trait Loci.

Miller CT, Glazer AM, Summers BR, Blackman BK, Norman AR, Shapiro MD, Cole BL, Peichel CL, Schluter D, Kingsley DM.

Genetics. 2014 May;197(1):405-20. doi: 10.1534/genetics.114.162420. Epub 2014 Mar 19.


A penile spine/vibrissa enhancer sequence is missing in modern and extinct humans but is retained in multiple primates with penile spines and sensory vibrissae.

Reno PL, McLean CY, Hines JE, Capellini TD, Bejerano G, Kingsley DM.

PLoS One. 2013 Dec 19;8(12):e84258. doi: 10.1371/journal.pone.0084258. eCollection 2013.


Single-step laser-based fabrication and patterning of cell-encapsulated alginate microbeads.

Kingsley DM, Dias AD, Chrisey DB, Corr DT.

Biofabrication. 2013 Dec;5(4):045006. doi: 10.1088/1758-5082/5/4/045006. Epub 2013 Nov 6.


Phylogeography and adaptation genetics of stickleback from the Haida Gwaii archipelago revealed using genome-wide single nucleotide polymorphism genotyping.

Deagle BE, Jones FC, Absher DM, Kingsley DM, Reimchen TE.

Mol Ecol. 2013 Apr;22(7):1917-32. doi: 10.1111/mec.12215. Epub 2013 Mar 4.


Pitx1 broadly associates with limb enhancers and is enriched on hindlimb cis-regulatory elements.

Infante CR, Park S, Mihala AG, Kingsley DM, Menke DB.

Dev Biol. 2013 Feb 1;374(1):234-44. doi: 10.1016/j.ydbio.2012.11.017. Epub 2012 Nov 27.


A "forward genomics" approach links genotype to phenotype using independent phenotypic losses among related species.

Hiller M, Schaar BT, Indjeian VB, Kingsley DM, Hagey LR, Bejerano G.

Cell Rep. 2012 Oct 25;2(4):817-23. doi: 10.1016/j.celrep.2012.08.032. Epub 2012 Sep 27.


Genetic architecture of variation in the lateral line sensory system of threespine sticklebacks.

Wark AR, Mills MG, Dang LH, Chan YF, Jones FC, Brady SD, Absher DM, Grimwood J, Schmutz J, Myers RM, Kingsley DM, Peichel CL.

G3 (Bethesda). 2012 Sep;2(9):1047-56. doi: 10.1534/g3.112.003079. Epub 2012 Sep 1.


Genetic signature of adaptive peak shift in threespine stickleback.

Rogers SM, Tamkee P, Summers B, Balabahadra S, Marks M, Kingsley DM, Schluter D.

Evolution. 2012 Aug;66(8):2439-50. doi: 10.1111/j.1558-5646.2012.01622.x. Epub 2012 Apr 9.


The genomic basis of adaptive evolution in threespine sticklebacks.

Jones FC, Grabherr MG, Chan YF, Russell P, Mauceli E, Johnson J, Swofford R, Pirun M, Zody MC, White S, Birney E, Searle S, Schmutz J, Grimwood J, Dickson MC, Myers RM, Miller CT, Summers BR, Knecht AK, Brady SD, Zhang H, Pollen AA, Howes T, Amemiya C; Broad Institute Genome Sequencing Platform & Whole Genome Assembly Team, Baldwin J, Bloom T, Jaffe DB, Nicol R, Wilkinson J, Lander ES, Di Palma F, Lindblad-Toh K, Kingsley DM.

Nature. 2012 Apr 4;484(7392):55-61. doi: 10.1038/nature10944.


A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence in sticklebacks.

Jones FC, Chan YF, Schmutz J, Grimwood J, Brady SD, Southwick AM, Absher DM, Myers RM, Reimchen TE, Deagle BE, Schluter D, Kingsley DM.

Curr Biol. 2012 Jan 10;22(1):83-90. doi: 10.1016/j.cub.2011.11.045. Epub 2011 Dec 22.


Population genomics of parallel phenotypic evolution in stickleback across stream-lake ecological transitions.

Deagle BE, Jones FC, Chan YF, Absher DM, Kingsley DM, Reimchen TE.

Proc Biol Sci. 2012 Apr 7;279(1732):1277-86. doi: 10.1098/rspb.2011.1552. Epub 2011 Oct 5.


Three periods of regulatory innovation during vertebrate evolution.

Lowe CB, Kellis M, Siepel A, Raney BJ, Clamp M, Salama SR, Kingsley DM, Lindblad-Toh K, Haussler D.

Science. 2011 Aug 19;333(6045):1019-24. doi: 10.1126/science.1202702. Erratum in: Science. 2011 Nov 11;334(6057):761.


Human-specific loss of regulatory DNA and the evolution of human-specific traits.

McLean CY, Reno PL, Pollen AA, Bassan AI, Capellini TD, Guenther C, Indjeian VB, Lim X, Menke DB, Schaar BT, Wenger AM, Bejerano G, Kingsley DM.

Nature. 2011 Mar 10;471(7337):216-9. doi: 10.1038/nature09774.


The progressive ankylosis protein regulates cementum apposition and extracellular matrix composition.

Foster BL, Nagatomo KJ, Bamashmous SO, Tompkins KA, Fong H, Dunn D, Chu EY, Guenther C, Kingsley DM, Rutherford RB, Somerman MJ.

Cells Tissues Organs. 2011;194(5):382-405. doi: 10.1159/000323457. Epub 2011 Mar 9.


The genetic basis of divergent pigment patterns in juvenile threespine sticklebacks.

Greenwood AK, Jones FC, Chan YF, Brady SD, Absher DM, Grimwood J, Schmutz J, Myers RM, Kingsley DM, Peichel CL.

Heredity (Edinb). 2011 Aug;107(2):155-66. doi: 10.1038/hdy.2011.1. Epub 2011 Feb 9.


Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage.

Dy P, Smits P, Silvester A, Penzo-Méndez A, Dumitriu B, Han Y, de la Motte CA, Kingsley DM, Lefebvre V.

Dev Biol. 2010 May 15;341(2):346-59. doi: 10.1016/j.ydbio.2010.02.024. Epub 2010 Mar 4.


Adaptive evolution of pelvic reduction in sticklebacks by recurrent deletion of a Pitx1 enhancer.

Chan YF, Marks ME, Jones FC, Villarreal G Jr, Shapiro MD, Brady SD, Southwick AM, Absher DM, Grimwood J, Schmutz J, Myers RM, Petrov D, Jónsson B, Schluter D, Bell MA, Kingsley DM.

Science. 2010 Jan 15;327(5963):302-5. doi: 10.1126/science.1182213. Epub 2009 Dec 10.


A role for a neo-sex chromosome in stickleback speciation.

Kitano J, Ross JA, Mori S, Kume M, Jones FC, Chan YF, Absher DM, Grimwood J, Schmutz J, Myers RM, Kingsley DM, Peichel CL.

Nature. 2009 Oct 22;461(7267):1079-83. doi: 10.1038/nature08441. Epub 2009 Sep 27.


The genetic architecture of skeletal convergence and sex determination in ninespine sticklebacks.

Shapiro MD, Summers BR, Balabhadra S, Aldenhoven JT, Miller AL, Cunningham CB, Bell MA, Kingsley DM.

Curr Biol. 2009 Jul 14;19(13):1140-5. doi: 10.1016/j.cub.2009.05.029. Epub 2009 Jun 4. Erratum in: Curr Biol. 2009 Jul 14;19(13):1156.


Muscle contraction is necessary to maintain joint progenitor cell fate.

Kahn J, Shwartz Y, Blitz E, Krief S, Sharir A, Breitel DA, Rattenbach R, Relaix F, Maire P, Rountree RB, Kingsley DM, Zelzer E.

Dev Cell. 2009 May;16(5):734-43. doi: 10.1016/j.devcel.2009.04.013.


From atoms to traits.

Kingsley DM.

Sci Am. 2009 Jan;300(1):52-9. No abstract available.


Shaping skeletal growth by modular regulatory elements in the Bmp5 gene.

Guenther C, Pantalena-Filho L, Kingsley DM.

PLoS Genet. 2008 Dec;4(12):e1000308. doi: 10.1371/journal.pgen.1000308. Epub 2008 Dec 19.

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