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Is ivermectin safe in pregnancy?

King CL.

Lancet Glob Health. 2020 Jan;8(1):e12-e13. doi: 10.1016/S2214-109X(19)30490-5. No abstract available.


Efficacy and safety of a single dose of ivermectin, diethylcarbamazine and albendazole for treatment of lymphatic filariasis in Côte d'Ivoire: an open-label, randomized, controlled trial.

Bjerum CM, Ouattara AF, Aboulaye M, Kouadio O, Marius VK, Andersen B, Weil GJ, Koudou BG, King CL.

Clin Infect Dis. 2019 Oct 23. pii: ciz1050. doi: 10.1093/cid/ciz1050. [Epub ahead of print]


Systems analysis-based assessment of post-treatment adverse events in lymphatic filariasis.

Andersen BJ, Rosa BA, Kupritz J, Meite A, Serge T, Hertz MI, Curtis K, King CL, Mitreva M, Fischer PU, Weil GJ.

PLoS Negl Trop Dis. 2019 Sep 26;13(9):e0007697. doi: 10.1371/journal.pntd.0007697. eCollection 2019 Sep.


Author Correction: Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP.

Urusova D, Carias L, Huang Y, Nicolete VC, Popovici J, Roesch C, Salinas ND, Dechavanne S, Witkowski B, Ferreira MU, Adams JH, Gross ML, King CL, Tolia NH.

Nat Microbiol. 2019 Nov;4(11):2024. doi: 10.1038/s41564-019-0587-2.


Comparison of repeated doses of ivermectin versus ivermectin plus albendazole for treatment of onchocerciasis - a randomized open-label clinical trial.

Batsa Debrah L, Klarmann-Schulz U, Osei-Mensah J, Dubben B, Fischer K, Mubarik Y, Ayisi-Boateng NK, Ricchiuto A, Fimmers R, Konadu P, Nadal J, Gruetzmacher B, Weil G, Kazura JW, King CL, Debrah AY, Hoerauf A.

Clin Infect Dis. 2019 Sep 19. pii: ciz889. doi: 10.1093/cid/ciz889. [Epub ahead of print]


Hypergammaglobulinemia and Impaired Transplacental Transfer of Respiratory Syncytial Virus Antibody in Papua New Guinea.

Atwell JE, Thumar B, Formica MA, Robinson LJ, Walsh EE, King CL, Karron RA.

Pediatr Infect Dis J. 2019 Sep;38(9):e199-e202. doi: 10.1097/INF.0000000000002364.


Dosing pole recommendations for lymphatic filariasis elimination: A height-weight quantile regression modeling approach.

Goss CW, O'Brian K, Dubray C, Fischer PU, Hardy M, Jambulingam P, King CL, Laman M, Lemoine JF, Robinson LJ, Samuela J, Subramanian S, Supali T, Weil GJ, Schechtman KB.

PLoS Negl Trop Dis. 2019 Jul 17;13(7):e0007541. doi: 10.1371/journal.pntd.0007541. eCollection 2019 Jul.


The safety of double- and triple-drug community mass drug administration for lymphatic filariasis: A multicenter, open-label, cluster-randomized study.

Weil GJ, Bogus J, Christian M, Dubray C, Djuardi Y, Fischer PU, Goss CW, Hardy M, Jambulingam P, King CL, Kuttiat VS, Krishnamoorthy K, Laman M, Lemoine JF, O'Brian KK, Robinson LJ, Samuela J, Schechtman KB, Sircar A, Srividya A, Steer AC, Supali T, Subramanian S; DOLF IDA Safety Study Group.

PLoS Med. 2019 Jun 24;16(6):e1002839. doi: 10.1371/journal.pmed.1002839. eCollection 2019 Jun.


Structural basis for neutralization of Plasmodium vivax by naturally acquired human antibodies that target DBP.

Urusova D, Carias L, Huang Y, Nicolete VC, Popovici J, Roesch C, Salinas ND, Dechavanne S, Witkowski B, Ferreira MU, Adams JH, Gross ML, King CL, Tolia NH.

Nat Microbiol. 2019 Sep;4(9):1486-1496. doi: 10.1038/s41564-019-0461-2. Epub 2019 May 27. Erratum in: Nat Microbiol. 2019 Sep 24;:.


Pharmacokinetics, safety, and efficacy of a single co-administered dose of diethylcarbamazine, albendazole and ivermectin in adults with and without Wuchereria bancrofti infection in Côte d'Ivoire.

Edi C, Bjerum CM, Ouattara AF, Chhonker YS, Penali LK, Méité A, Koudou BG, Weil GJ, King CL, Murry DJ.

PLoS Negl Trop Dis. 2019 May 20;13(5):e0007325. doi: 10.1371/journal.pntd.0007325. eCollection 2019 May.


Identification of an Immunogenic Broadly Inhibitory Surface Epitope of the Plasmodium vivax Duffy Binding Protein Ligand Domain.

George MT, Schloegel JL, Ntumngia FB, Barnes SJ, King CL, Casey JL, Foley M, Adams JH.

mSphere. 2019 May 15;4(3). pii: e00194-19. doi: 10.1128/mSphere.00194-19.


Human Migration and the Spread of the Nematode Parasite Wuchereria bancrofti.

Small ST, Labbé F, Coulibaly YI, Nutman TB, King CL, Serre D, Zimmerman PA.

Mol Biol Evol. 2019 Sep 1;36(9):1931-1941. doi: 10.1093/molbev/msz116.


Identification and Characterization of Functional Human Monoclonal Antibodies to Plasmodium vivax Duffy-Binding Protein.

Carias LL, Dechavanne S, Nicolete VC, Sreng S, Suon S, Amaratunga C, Fairhurst RM, Dechavanne C, Barnes S, Witkowski B, Popovici J, Roesch C, Chen E, Ferreira MU, Tolia NH, Adams JH, King CL.

J Immunol. 2019 May 1;202(9):2648-2660. doi: 10.4049/jimmunol.1801631. Epub 2019 Apr 3.


Antibody responses to Plasmodium vivax Duffy binding and Erythrocyte binding proteins predict risk of infection and are associated with protection from clinical Malaria.

He WQ, Shakri AR, Bhardwaj R, França CT, Stanisic DI, Healer J, Kiniboro B, Robinson LJ, Guillotte-Blisnick M, Huon C, Siba P, Cowman A, King CL, Tham WH, Chitnis CE, Mueller I.

PLoS Negl Trop Dis. 2019 Feb 15;13(2):e0006987. doi: 10.1371/journal.pntd.0006987. eCollection 2019 Feb.


Combining different diagnostic studies of lymphatic filariasis for risk mapping in Papua New Guinea: a predictive model from microfilaraemia and antigenaemia prevalence surveys.

Berg Soto A, Xu Z, Wood P, Sanuku N, Robinson LJ, King CL, Tisch D, Susapu M, Graves PM.

Trop Med Health. 2018 Dec 4;46:41. doi: 10.1186/s41182-018-0123-8. eCollection 2018.


A Trial of a Triple-Drug Treatment for Lymphatic Filariasis.

King CL, Suamani J, Sanuku N, Cheng YC, Satofan S, Mancuso B, Goss CW, Robinson LJ, Siba PM, Weil GJ, Kazura JW.

N Engl J Med. 2018 Nov 8;379(19):1801-1810. doi: 10.1056/NEJMoa1706854.


Update on the current status of onchocerciasis in Côte d'Ivoire following 40 years of intervention: Progress and challenges.

Koudou BG, Kouakou MM, Ouattara AF, Yeo S, Brika P, Meite A, Aba E, King CL, Kouakou R, Weil GJ, Fischer PU.

PLoS Negl Trop Dis. 2018 Oct 23;12(10):e0006897. doi: 10.1371/journal.pntd.0006897. eCollection 2018 Oct.


Iron deficiency during pregnancy is associated with a reduced risk of adverse birth outcomes in a malaria-endemic area in a longitudinal cohort study.

Fowkes FJI, Moore KA, Opi DH, Simpson JA, Langham F, Stanisic DI, Ura A, King CL, Siba PM, Mueller I, Rogerson SJ, Beeson JG.

BMC Med. 2018 Sep 20;16(1):156. doi: 10.1186/s12916-018-1146-z.


Australian caregivers' perceptions of influenza vaccination in pregnancy: A mixed methods exploration.

King CL, Chow MY, Leask J, Wiley KE.

Women Birth. 2019 Jun;32(3):240-245. doi: 10.1016/j.wombi.2018.07.010. Epub 2018 Aug 8.


Identification and Immunological Characterization of the Ligand Domain of Plasmodium vivax Reticulocyte Binding Protein 1a.

Ntumngia FB, Thomson-Luque R, Galusic S, Frato G, Frischmann S, Peabody DS, Chackerian B, Ferreira MU, King CL, Adams JH.

J Infect Dis. 2018 Aug 24;218(7):1110-1118. doi: 10.1093/infdis/jiy273.


Much ado about flu: A mixed methods study of parental perceptions, trust and information seeking in a pandemic.

King CL, Chow MYK, Wiley KE, Leask J.

Influenza Other Respir Viruses. 2018 Jul;12(4):514-521. doi: 10.1111/irv.12547. Epub 2018 Mar 13.


Cord Blood Antiparasite Interleukin 10 as a Risk Marker for Compromised Vaccine Immunogenicity in Early Childhood.

Malhotra I, LaBeaud AD, Morris N, McKibben M, Mungai P, Muchiri E, King CL, King CH.

J Infect Dis. 2018 Apr 11;217(9):1426-1434. doi: 10.1093/infdis/jiy047.


Let's talk about stress, baby! Infant-feeding practices and stress in the ancient Atacama desert, Northern Chile.

King CL, Halcrow SE, Millard AR, Gröcke DR, Standen VG, Portilla M, Arriaza BT.

Am J Phys Anthropol. 2018 May;166(1):139-155. doi: 10.1002/ajpa.23411. Epub 2018 Jan 22.


Changes in Cytokine, Filarial Antigen, and DNA Levels Associated With Adverse Events Following Treatment of Lymphatic Filariasis.

Andersen BJ, Kumar J, Curtis K, Sanuku N, Satofan S, King CL, Fischer PU, Weil GJ.

J Infect Dis. 2018 Jan 4;217(2):280-287. doi: 10.1093/infdis/jix578. Erratum in: J Infect Dis. 2018 Mar 28;217(8):1334.


Uniportal video-assisted thoracoscopic surgery (VATS) technique is associated with decreased narcotic usage over traditional VATS lobectomy.

Louis SG, Gibson WJ, King CL, Veeramachaneni NK.

J Vis Surg. 2017 Sep 14;3:117. doi: 10.21037/jovs.2017.08.05. eCollection 2017.


An engineered vaccine of the Plasmodium vivax Duffy binding protein enhances induction of broadly neutralizing antibodies.

Ntumngia FB, Pires CV, Barnes SJ, George MT, Thomson-Luque R, Kano FS, Alves JRS, Urusova D, Pereira DB, Tolia NH, King CL, Carvalho LH, Adams JH.

Sci Rep. 2017 Oct 23;7(1):13779. doi: 10.1038/s41598-017-13891-2.


P. falciparum infection and maternofetal antibody transfer in malaria-endemic settings of varying transmission.

McLean ARD, Stanisic D, McGready R, Chotivanich K, Clapham C, Baiwog F, Pimanpanarak M, Siba P, Mueller I, King CL, Nosten F, Beeson JG, Rogerson S, Simpson JA, Fowkes FJI.

PLoS One. 2017 Oct 13;12(10):e0186577. doi: 10.1371/journal.pone.0186577. eCollection 2017.


Associations between an IgG3 polymorphism in the binding domain for FcRn, transplacental transfer of malaria-specific IgG3, and protection against Plasmodium falciparum malaria during infancy: A birth cohort study in Benin.

Dechavanne C, Dechavanne S, Sadissou I, Lokossou AG, Alvarado F, Dambrun M, Moutairou K, Courtin D, Nuel G, Garcia A, Migot-Nabias F, King CL.

PLoS Med. 2017 Oct 9;14(10):e1002403. doi: 10.1371/journal.pmed.1002403. eCollection 2017 Oct.


Identification of highly-protective combinations of Plasmodium vivax recombinant proteins for vaccine development.

França CT, White MT, He WQ, Hostetler JB, Brewster J, Frato G, Malhotra I, Gruszczyk J, Huon C, Lin E, Kiniboro B, Yadava A, Siba P, Galinski MR, Healer J, Chitnis C, Cowman AF, Takashima E, Tsuboi T, Tham WH, Fairhurst RM, Rayner JC, King CL, Mueller I.

Elife. 2017 Sep 26;6. pii: e28673. doi: 10.7554/eLife.28673.


Patterns of protective associations differ for antibodies to P. falciparum-infected erythrocytes and merozoites in immunity against malaria in children.

Chan JA, Stanisic DI, Duffy MF, Robinson LJ, Lin E, Kazura JW, King CL, Siba PM, Fowkes FJ, Mueller I, Beeson JG.

Eur J Immunol. 2017 Dec;47(12):2124-2136. doi: 10.1002/eji.201747032. Epub 2017 Sep 13.


Parental disease prevention health beliefs and triggers for keeping children home from childcare-a qualitative study in Sydney, Australia.

King CL, Leask J.

Child Care Health Dev. 2018 Mar;44(2):326-331. doi: 10.1111/cch.12481. Epub 2017 Jun 15.


Asymptomatic Plasmodium vivax infections induce robust IgG responses to multiple blood-stage proteins in a low-transmission region of western Thailand.

Longley RJ, França CT, White MT, Kumpitak C, Sa-Angchai P, Gruszczyk J, Hostetler JB, Yadava A, King CL, Fairhurst RM, Rayner JC, Tham WH, Nguitragool W, Sattabongkot J, Mueller I.

Malar J. 2017 Apr 28;16(1):178. doi: 10.1186/s12936-017-1826-8.


Pneumococcal Vaccine Response After Exposure to Parasites in Utero, in Infancy, or Mid-Childhood.

Nayakwadi Singer M, Heath C, Muinde J, Gildengorin V, Mutuku FM, Vu D, Mukoko D, King CL, Malhotra IJ, King CH, LaBeaud AD.

Pediatrics. 2017 Apr;139(4). pii: e20162781. doi: 10.1542/peds.2016-2781. Epub 2017 Mar 16.


Potential Value of Triple Drug Therapy with Ivermectin, Diethylcarbamazine, and Albendazole (IDA) to Accelerate Elimination of Lymphatic Filariasis and Onchocerciasis in Africa.

Fischer PU, King CL, Jacobson JA, Weil GJ.

PLoS Negl Trop Dis. 2017 Jan 5;11(1):e0005163. doi: 10.1371/journal.pntd.0005163. eCollection 2017 Jan. No abstract available.


Naturally Acquired Binding-Inhibitory Antibodies to Plasmodium vivax Duffy Binding Protein and Clinical Immunity to Malaria in Rural Amazonians.

Nicolete VC, Frischmann S, Barbosa S, King CL, Ferreira MU.

J Infect Dis. 2016 Nov 15;214(10):1539-1546. Epub 2016 Aug 30.


Adhesion of Plasmodium falciparum infected erythrocytes in ex vivo perfused placental tissue: a novel model of placental malaria.

Pehrson C, Mathiesen L, Heno KK, Salanti A, Resende M, Dzikowski R, Damm P, Hansson SR, King CL, Schneider H, Wang CW, Lavstsen T, Theander TG, Knudsen LE, Nielsen MA.

Malar J. 2016 May 26;15(1):292. doi: 10.1186/s12936-016-1342-2.


An Antibody Screen of a Plasmodium vivax Antigen Library Identifies Novel Merozoite Proteins Associated with Clinical Protection.

França CT, Hostetler JB, Sharma S, White MT, Lin E, Kiniboro B, Waltmann A, Darcy AW, Li Wai Suen CS, Siba P, King CL, Rayner JC, Fairhurst RM, Mueller I.

PLoS Negl Trop Dis. 2016 May 16;10(5):e0004639. doi: 10.1371/journal.pntd.0004639. eCollection 2016 May.


Protective Effect of Chronic Schistosomiasis in Baboons Coinfected with Schistosoma mansoni and Plasmodium knowlesi.

Nyakundi RK, Nyamongo O, Maamun J, Akinyi M, Mulei I, Farah IO, Blankenship D, Grimberg B, Hau J, Malhotra I, Ozwara H, King CL, Kariuki TM.

Infect Immun. 2016 Apr 22;84(5):1320-1330. doi: 10.1128/IAI.00490-15. Print 2016 May.


Population genomics of the filarial nematode parasite Wuchereria bancrofti from mosquitoes.

Small ST, Reimer LJ, Tisch DJ, King CL, Christensen BM, Siba PM, Kazura JW, Serre D, Zimmerman PA.

Mol Ecol. 2016 Apr;25(7):1465-77. doi: 10.1111/mec.13574. Epub 2016 Mar 15.


Circulating protein synthesis rates reveal skeletal muscle proteome dynamics.

Shankaran M, King CL, Angel TE, Holmes WE, Li KW, Colangelo M, Price JC, Turner SM, Bell C, Hamilton KL, Miller BF, Hellerstein MK.

J Clin Invest. 2016 Jan;126(1):288-302. doi: 10.1172/JCI79639. Epub 2015 Dec 14.


Contrasting Patterns of Serologic and Functional Antibody Dynamics to Plasmodium falciparum Antigens in a Kenyan Birth Cohort.

Dent AE, Malhotra I, Wang X, Babineau D, Yeo KT, Anderson T, Kimmel RJ, Angov E, Lanar DE, Narum D, Dutta S, Richards J, Beeson JG, Crabb BS, Cowman AF, Horii T, Muchiri E, Mungai PL, King CL, Kazura JW.

Clin Vaccine Immunol. 2015 Dec 9;23(2):104-16. doi: 10.1128/CVI.00452-15. Print 2016 Feb.


Efficacy, Safety, and Pharmacokinetics of Coadministered Diethylcarbamazine, Albendazole, and Ivermectin for Treatment of Bancroftian Filariasis.

Thomsen EK, Sanuku N, Baea M, Satofan S, Maki E, Lombore B, Schmidt MS, Siba PM, Weil GJ, Kazura JW, Fleckenstein LL, King CL.

Clin Infect Dis. 2016 Feb 1;62(3):334-341. doi: 10.1093/cid/civ882. Epub 2015 Oct 20.


Letter to the editor: Response to Oxenham and Matsumura.

King CL, Tayles N, Higham C, Strand-Viđarsdóttir U, AlexanderBentley R, Macpherson CG, Nowell G.

Am J Phys Anthropol. 2016 Feb;159(2):352-4. doi: 10.1002/ajpa.22875. Epub 2015 Sep 26. No abstract available.


Inflammatory Pseudotumor of the Liver with Escherichia coli in the Sputum.

Narayan S, Nayak A, King CL.

Case Rep Med. 2015;2015:249210. doi: 10.1155/2015/249210. Epub 2015 Aug 12.


Biosignatures of Exposure/Transmission and Immunity.

King CL, Davies DH, Felgner P, Baum E, Jain A, Randall A, Tetteh K, Drakeley CJ, Greenhouse B.

Am J Trop Med Hyg. 2015 Sep;93(3 Suppl):16-27. doi: 10.4269/ajtmh.15-0037. Epub 2015 Aug 10.


Impact of Placental Malaria and Hypergammaglobulinemia on Transplacental Transfer of Respiratory Syncytial Virus Antibody in Papua New Guinea.

Atwell JE, Thumar B, Robinson LJ, Tobby R, Yambo P, Ome-Kaius M, Siba PM, Unger HW, Rogerson SJ, King CL, Karron RA.

J Infect Dis. 2016 Feb 1;213(3):423-31. doi: 10.1093/infdis/jiv401. Epub 2015 Aug 3.


Using isotopic evidence to assess the impact of migration and the two-layer hypothesis in prehistoric Northeast Thailand.

King CL, Tayles N, Higham C, Strand-Viđarsdóttir U, Bentley RA, Macpherson CG, Nowell G.

Am J Phys Anthropol. 2015 Sep;158(1):141-50. doi: 10.1002/ajpa.22772. Epub 2015 Jun 29.


Parasitism in Children Aged Three Years and Under: Relationship between Infection and Growth in Rural Coastal Kenya.

LaBeaud AD, Nayakwadi Singer M, McKibben M, Mungai P, Muchiri EM, McKibben E, Gildengorin G, Sutherland LJ, King CH, King CL, Malhotra I.

PLoS Negl Trop Dis. 2015 May 21;9(5):e0003721. doi: 10.1371/journal.pntd.0003721. eCollection 2015 May.


Parasite accumulation in placenta of non-immune baboons during Plasmodium knowlesi infection.

Onditi FI, Nyamongo OW, Omwandho CO, Maina NW, Maloba F, Farah IO, King CL, Moore JM, Ozwara HS.

Malar J. 2015 Mar 18;14:118. doi: 10.1186/s12936-015-0631-5.

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