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Items: 41

1.

A Microfluidic Perfusion Platform for In Vitro Analysis of Drug Pharmacokinetic-Pharmacodynamic (PK-PD) Relationships.

Guerrero YA, Desai D, Sullivan C, Kindt E, Spilker ME, Maurer TS, Solomon DE, Bartlett DW.

AAPS J. 2020 Mar 2;22(2):53. doi: 10.1208/s12248-020-0430-y.

PMID:
32124093
2.

Development of an In Vivo Retrodialysis Calibration Method Using Stable Isotope Labeling to Monitor Metabolic Pathways in the Tumor Microenvironment via Microdialysis.

Bartlett DW, Wu A, Li X, Kraus M, Wang H, Kindt E.

J Pharm Sci. 2019 Sep;108(9):3124-3129. doi: 10.1016/j.xphs.2019.05.016. Epub 2019 May 25.

PMID:
31136767
3.

Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice.

Cokorinos EC, Delmore J, Reyes AR, Albuquerque B, Kjøbsted R, Jørgensen NO, Tran JL, Jatkar A, Cialdea K, Esquejo RM, Meissen J, Calabrese MF, Cordes J, Moccia R, Tess D, Salatto CT, Coskran TM, Opsahl AC, Flynn D, Blatnik M, Li W, Kindt E, Foretz M, Viollet B, Ward J, Kurumbail RG, Kalgutkar AS, Wojtaszewski JFP, Cameron KO, Miller RA.

Cell Metab. 2017 May 2;25(5):1147-1159.e10. doi: 10.1016/j.cmet.2017.04.010.

4.

Identification and Evaluation of Novel MicroRNA Biomarkers in Plasma and Feces Associated with Drug-induced Intestinal Toxicity.

Kalabat DY, Vitsky A, Scott W, Kindt E, Hayes K, John-Baptiste A, Huang W, Yang AH.

Toxicol Pathol. 2017 Feb;45(2):302-320. doi: 10.1177/0192623316644992. Epub 2016 Jul 11.

PMID:
27189632
5.

Liquid chromatography-tandem mass spectrometry method for quantification of thymidine kinase activity in human serum by monitoring the conversion of 3'-deoxy-3'-fluorothymidine to 3'-deoxy-3'-fluorothymidine monophosphate.

Faria M, Halquist MS, Kindt E, Li W, Karnes HT, O'Brien PJ.

J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Oct 15;907:13-20. doi: 10.1016/j.jchromb.2012.08.024. Epub 2012 Aug 24.

PMID:
22995377
6.

Evaluation of potential gastrointestinal biomarkers in a PAK4 inhibitor-treated preclinical toxicity model to address unmonitorable gastrointestinal toxicity.

John-Baptiste A, Huang W, Kindt E, Wu A, Vitsky A, Scott W, Gross C, Yang AH, Schaiff WT, Ramaiah SK.

Toxicol Pathol. 2012 Apr;40(3):482-90. doi: 10.1177/0192623311432289. Epub 2012 Mar 6.

PMID:
22395791
7.

Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: a bench-to-bedside case study on tissue selective drug distribution.

Pfefferkorn JA, Litchfield J, Hutchings R, Cheng XM, Larsen SD, Auerbach B, Bush MR, Lee C, Erasga N, Bowles DM, Boyles DC, Lu G, Sekerke C, Askew V, Hanselman JC, Dillon L, Lin Z, Robertson A, Olsen K, Boustany C, Atkinson K, Goosen TC, Sahasrabudhe V, Chupka J, Duignan DB, Feng B, Scialis R, Kimoto E, Bi YA, Lai Y, El-Kattan A, Bakker-Arkema R, Barclay P, Kindt E, Le V, Mandema JW, Milad M, Tait BD, Kennedy R, Trivedi BK, Kowala M.

Bioorg Med Chem Lett. 2011 May 1;21(9):2725-31. doi: 10.1016/j.bmcl.2010.11.103. Epub 2010 Nov 26.

PMID:
21183342
8.

The validation of a simple LC/MS/MS method for determining the level of mevalonic acid in human plasma.

Kindt E, Szekely-Klepser G, Fountain ST.

Biomed Chromatogr. 2011 Mar;25(3):323-9. doi: 10.1002/bmc.1449.

PMID:
21110384
9.

Quantitative sphingosine measurement as a surrogate for total ceramide concentration-preclinical and potential translational applications.

Kindt E, Wetterau J, Mueller SB, Castle C, Boustany-Kari CM.

Biomed Chromatogr. 2010 Jul;24(7):752-8. doi: 10.1002/bmc.1359.

PMID:
19908207
10.

Creating a fatty acid methyl ester database for lipid profiling in a single drop of human blood using high resolution capillary gas chromatography and mass spectrometry.

Bicalho B, David F, Rumplel K, Kindt E, Sandra P.

J Chromatogr A. 2008 Nov 21;1211(1-2):120-8. doi: 10.1016/j.chroma.2008.09.066. Epub 2008 Sep 25.

PMID:
18842268
11.

Serine palmitoyltransferase inhibitor myriocin induces the regression of atherosclerotic plaques in hyperlipidemic ApoE-deficient mice.

Park TS, Rosebury W, Kindt EK, Kowala MC, Panek RL.

Pharmacol Res. 2008 Jul;58(1):45-51. doi: 10.1016/j.phrs.2008.06.005. Epub 2008 Jun 20.

PMID:
18611440
12.

Modulation of lipoprotein metabolism by inhibition of sphingomyelin synthesis in ApoE knockout mice.

Park TS, Panek RL, Rekhter MD, Mueller SB, Rosebury WS, Robertson A, Hanselman JC, Kindt E, Homan R, Karathanasis SK.

Atherosclerosis. 2006 Dec;189(2):264-72. Epub 2006 Feb 2.

PMID:
16458317
13.

A validated LC/MS/MS method for the quantification of pyrrole-2,3,5-tricarboxylic acid (PTCA), a eumelanin specific biomarker, in human skin punch biopsies.

Szekely-Klepser G, Wade K, Woolson D, Brown R, Fountain S, Kindt E.

J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Nov 5;826(1-2):31-40. Epub 2005 Aug 31.

PMID:
16139575
14.

Inhibition of sphingomyelin synthesis reduces atherogenesis in apolipoprotein E-knockout mice.

Park TS, Panek RL, Mueller SB, Hanselman JC, Rosebury WS, Robertson AW, Kindt EK, Homan R, Karathanasis SK, Rekhter MD.

Circulation. 2004 Nov 30;110(22):3465-71. Epub 2004 Nov 15.

PMID:
15545514
15.

Development and validation of an LC/MS/MS procedure for the quantification of endogenous myo-inositol concentrations in rat brain tissue homogenates.

Kindt E, Shum Y, Badura L, Snyder PJ, Brant A, Fountain S, Szekely-Klepser G.

Anal Chem. 2004 Aug 15;76(16):4901-8.

PMID:
15307804
16.

Determination of hydroxyproline in plasma and tissue using electrospray mass spectrometry.

Kindt E, Gueneva-Boucheva K, Rekhter MD, Humphries J, Hallak H.

J Pharm Biomed Anal. 2003 Dec 4;33(5):1081-92.

PMID:
14656599
17.

Quantitative bioanalysis of enantiomeric drugs using capillary electrophoresis and electrospray mass spectrometry.

Kindt EK, Kurzyniec S, Wang SC, Kilby G, Rossi DT.

J Pharm Biomed Anal. 2003 Apr 1;31(5):893-904.

PMID:
12684102
18.

Molecular sieving and mass spectroscopy reveal enhanced collagen degradation in rabbit atheroma.

Chen J, Kindt E, Hallak H, Peterson JT, Rosebury WS, Hubbel AM, Bocan TM, Rekhter MD.

Atherosclerosis. 2001 Dec;159(2):289-95.

PMID:
11730808
19.

The effect of troglitazone biliary excretion on metabolite distribution and cholestasis in transporter-deficient rats.

Kostrubsky VE, Vore M, Kindt E, Burliegh J, Rogers K, Peter G, Altrogge D, Sinz MW.

Drug Metab Dispos. 2001 Dec;29(12):1561-6.

PMID:
11717175
20.

Troglitazone quinone formation catalyzed by human and rat CYP3A: an atypical CYP oxidation reaction.

He K, Woolf TF, Kindt EK, Fielder AE, Talaat RE.

Biochem Pharmacol. 2001 Jul 15;62(2):191-8.

PMID:
11389877
21.

The role of conjugation in hepatotoxicity of troglitazone in human and porcine hepatocyte cultures.

Kostrubsky VE, Sinclair JF, Ramachandran V, Venkataramanan R, Wen YH, Kindt E, Galchev V, Rose K, Sinz M, Strom SC.

Drug Metab Dispos. 2000 Oct;28(10):1192-7.

PMID:
10997939
22.

Quantitative method for biomarkers of collagen degradation using liquid chromatography tandem mass spectrometry.

Kindt E, Rossi DT, Gueneva-Boucheva K, Hallak H.

Anal Biochem. 2000 Jul 15;283(1):71-6.

PMID:
10929810
23.

Hypercholesterolemia causes mechanical weakening of rabbit atheroma : local collagen loss as a prerequisite of plaque rupture.

Rekhter MD, Hicks GW, Brammer DW, Hallak H, Kindt E, Chen J, Rosebury WS, Anderson MK, Kuipers PJ, Ryan MJ.

Circ Res. 2000 Jan 7-21;86(1):101-8.

PMID:
10625311
24.

Reduced nutritional status in an elderly population (> 70 y) is probable before disease and possibly contributes to the development of disease.

Mowé M, Bøhmer T, Kindt E.

Am J Clin Nutr. 1994 Feb;59(2):317-24. Erratum in: Am J Clin Nutr 1994 Aug;60(2):298.

PMID:
8310980
25.
26.

Simultaneous assay of corticosterone and cortisol in plasma by reversed-phase liquid chromatography.

Hariharan M, Naga S, VanNoord T, Kindt EK.

Clin Chem. 1992 Mar;38(3):346-52.

PMID:
1547550
27.

A simple, sensitive liquid chromatographic assay of cis-thiothixene in plasma with coulometric detection.

Hariharan M, VanNoord T, Kindt EK, Tandon R.

Ther Drug Monit. 1991 Jan;13(1):79-85.

PMID:
1676194
28.

[Children with phenylketonuria (Fölling's disease). Intellectual functions and psychological adaptation].

Aarseth J, Vandvik IH, Heyerdahl S, Kindt E, Motzfeldt K, Halvorsen S.

Tidsskr Nor Laegeforen. 1989 Nov 30;109(33):3416-8. Norwegian.

PMID:
2609302
30.

Fasting plasma amino acid concentrations in PKU children on two different levels of protein intake.

Kindt E, Lunde HA, Gjessing LR, Halvorsen S, Lie SO.

Acta Paediatr Scand. 1988 Jan;77(1):60-6.

PMID:
3369307
31.

Does a marginal protein intake result in osteoporosis?

Kindt E, Halvorsen S, Lie SO.

J Inherit Metab Dis. 1987;10(2):195. No abstract available.

PMID:
3116338
32.

Physical and mental performance of soldiers on high- and low-energy diets during prolonged heavy exercise combined with sleep deprivation.

Rognum TO, Vartdal F, Rodahl K, Opstad PK, Knudsen-Baas O, Kindt E, Withey WR.

Ergonomics. 1986 Jul;29(7):859-67. No abstract available.

PMID:
3743541
33.
34.

Is phenylalanine requirement in infants and children related to protein intake?

Kindt E, Motzfeldt K, Halvorsen S, Lie SO.

Br J Nutr. 1984 May;51(3):435-42.

PMID:
6722086
35.

Protein requirements in infants and children: a longitudinal study of children treated for phenylketonuria.

Kindt E, Motzfeldt K, Halvorsen S, Lie SO.

Am J Clin Nutr. 1983 May;37(5):778-85.

PMID:
6687778
37.

[Fat cell size in 14 female overweight patients].

Rognum TO, Kindt E.

Tidsskr Nor Laegeforen. 1973 Sep 10;93(25):1737-9. Norwegian. No abstract available.

PMID:
4771906
38.

[Diet with inborn errors of metabolism].

Halvorsen S, Haneborg B, Kindt E.

Tidsskr Nor Laegeforen. 1972 Sep 20;92(26):1683-6. Norwegian. No abstract available.

PMID:
5078273
39.

[Sacral anesthesia in obstetrics].

KINDT E.

Ugeskr Laeger. 1960 Dec 9;122:1718-9. Danish. No abstract available.

PMID:
13756056
40.

Abacterial pyuria.

KINDT E.

Acta Chir Scand. 1953;105(1-4):182-7. No abstract available.

PMID:
13079502
41.

[Transurethral prostatectomy in prostatism].

KINDT E.

Nord Med. 1950 Jul 14;44(28):1135-40. Undetermined Language. No abstract available.

PMID:
14797082

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