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Items: 31


Tocopherol biosynthesis in Leishmania (L.) amazonensis promastigotes.

Balanco JMF, Sussmann RAC, Verdaguer IB, Gabriel HB, Kimura EA, Katzin AM.

FEBS Open Bio. 2019 Mar 5;9(4):743-754. doi: 10.1002/2211-5463.12613. eCollection 2019 Apr.


Plasmodium falciparum parasites overexpressing farnesyl diphosphate synthase/geranylgeranyl diphosphate synthase are more resistant to risedronate.

Gabriel HB, Azevedo MF, Kimura EA, Katzin AM.

Mem Inst Oswaldo Cruz. 2018;113(10):e180174. doi: 10.1590/0074-02760180174. Epub 2018 Aug 13.


Plasmodium falciparum uses vitamin E to avoid oxidative stress.

Sussmann RAC, Fotoran WL, Kimura EA, Katzin AM.

Parasit Vectors. 2017 Oct 10;10(1):461. doi: 10.1186/s13071-017-2402-3.


Perillyl alcohol exhibits in vitro inhibitory activity against Plasmodium falciparum and protects against experimental cerebral malaria.

Rodriguez AAM, Carvalho LJM, Kimura EA, Katzin AM.

Int J Antimicrob Agents. 2018 Mar;51(3):370-377. doi: 10.1016/j.ijantimicag.2017.08.025. Epub 2017 Aug 23.


Antimalarial activity of the terpene nerolidol.

Saito AY, Marin Rodriguez AA, Menchaca Vega DS, Sussmann RAC, Kimura EA, Katzin AM.

Int J Antimicrob Agents. 2016 Dec;48(6):641-646. doi: 10.1016/j.ijantimicag.2016.08.017. Epub 2016 Sep 30.


Single-target high-throughput transcription analyses reveal high levels of alternative splicing present in the FPPS/GGPPS from Plasmodium falciparum.

Gabriel HB, de Azevedo MF, Palmisano G, Wunderlich G, Kimura EA, Katzin AM, Alves JM.

Sci Rep. 2015 Dec 21;5:18429. doi: 10.1038/srep18429.


Quantification of nerolidol in mouse plasma using gas chromatography-mass spectrometry.

Saito AY, Sussmann RA, Kimura EA, Cassera MB, Katzin AM.

J Pharm Biomed Anal. 2015;111:100-3. doi: 10.1016/j.jpba.2015.03.030. Epub 2015 Apr 3.


Squalestatin is an inhibitor of carotenoid biosynthesis in Plasmodium falciparum.

Gabriel HB, Silva MF, Kimura EA, Wunderlich G, Katzin AM, Azevedo MF.

Antimicrob Agents Chemother. 2015;59(6):3180-8. doi: 10.1128/AAC.04500-14. Epub 2015 Mar 16.


Cloning and characterization of bifunctional enzyme farnesyl diphosphate/geranylgeranyl diphosphate synthase from Plasmodium falciparum.

Jordão FM, Gabriel HB, Alves JM, Angeli CB, Bifano TD, Breda A, de Azevedo MF, Basso LA, Wunderlich G, Kimura EA, Katzin AM.

Malar J. 2013 Jun 4;12:184. doi: 10.1186/1475-2875-12-184.


Intraerythrocytic stages of Plasmodium falciparum biosynthesize vitamin E.

Sussmann RA, Angeli CB, Peres VJ, Kimura EA, Katzin AM.

FEBS Lett. 2011 Dec 15;585(24):3985-91. doi: 10.1016/j.febslet.2011.11.005. Epub 2011 Nov 12.


Isoprenoid biosynthesis in the erythrocytic stages of Plasmodium falciparum.

Jordão FM, Kimura EA, Katzin AM.

Mem Inst Oswaldo Cruz. 2011 Aug;106 Suppl 1:134-41. Review.


In vitro and in vivo antiplasmodial activities of risedronate and its interference with protein prenylation in Plasmodium falciparum.

Jordão FM, Saito AY, Miguel DC, de Jesus Peres V, Kimura EA, Katzin AM.

Antimicrob Agents Chemother. 2011 May;55(5):2026-31. doi: 10.1128/AAC.01820-10. Epub 2011 Feb 28.


Intraerythrocytic stages of Plasmodium falciparum biosynthesize menaquinone.

Tonhosolo R, Gabriel HB, Matsumura MY, Cabral FJ, Yamamoto MM, D'Alexandri FL, Sussmann RAC, Belmonte R, Peres VJ, Crick DC, Wunderlich G, Kimura EA, Katzin AM.

FEBS Lett. 2010 Dec 1;584(23):4761-4768. doi: 10.1016/j.febslet.2010.10.055. Epub 2010 Oct 29.


Mass spectrometry analysis of polyisoprenoids alcohols and carotenoids via ESI(Li(+))-MS/MS.

D'Alexandri FL, Tonhosolo R, Kimura EA, Katzin AM.

Methods Mol Biol. 2009;580:109-28. doi: 10.1007/978-1-60761-325-1_6.


Carotenoid biosynthesis in intraerythrocytic stages of Plasmodium falciparum.

Tonhosolo R, D'Alexandri FL, de Rosso VV, Gazarini ML, Matsumura MY, Peres VJ, Merino EF, Carlton JM, Wunderlich G, Mercadante AZ, Kimura EA, Katzin AM.

J Biol Chem. 2009 Apr 10;284(15):9974-85. doi: 10.1074/jbc.M807464200. Epub 2009 Feb 9.


Effect of fosmidomycin on metabolic and transcript profiles of the methylerythritol phosphate pathway in Plasmodium falciparum.

Cassera MB, Merino EF, Peres VJ, Kimura EA, Wunderlich G, Katzin AM.

Mem Inst Oswaldo Cruz. 2007 Jun;102(3):377-83.


Protein dolichylation in Plasmodium falciparum.

D'Alexandri FL, Kimura EA, Peres VJ, Katzin AM.

FEBS Lett. 2006 Nov 27;580(27):6343-8. Epub 2006 Oct 30.


Identification, molecular cloning and functional characterization of an octaprenyl pyrophosphate synthase in intra-erythrocytic stages of Plasmodium falciparum.

Tonhosolo R, D'Alexandri FL, Genta FA, Wunderlich G, Gozzo FC, Eberlin MN, Peres VJ, Kimura EA, Katzin AM.

Biochem J. 2005 Nov 15;392(Pt 1):117-26.


The methylerythritol phosphate pathway is functionally active in all intraerythrocytic stages of Plasmodium falciparum.

Cassera MB, Gozzo FC, D'Alexandri FL, Merino EF, del Portillo HA, Peres VJ, Almeida IC, Eberlin MN, Wunderlich G, Wiesner J, Jomaa H, Kimura EA, Katzin AM.

J Biol Chem. 2004 Dec 10;279(50):51749-59. Epub 2004 Sep 27.


Terpenes arrest parasite development and inhibit biosynthesis of isoprenoids in Plasmodium falciparum.

Rodrigues Goulart H, Kimura EA, Peres VJ, Couto AS, Aquino Duarte FA, Katzin AM.

Antimicrob Agents Chemother. 2004 Jul;48(7):2502-9.


Farnesyltransferase inhibitors inhibit the growth of malaria parasites in vitro and in vivo.

Wiesner J, Kettler K, Sakowski J, Ortmann R, Katzin AM, Kimura EA, Silber K, Klebe G, Jomaa H, Schlitzer M.

Angew Chem Int Ed Engl. 2004 Jan;43(2):251-4. No abstract available.


Characterization of the isoprenoid chain of coenzyme Q in Plasmodium falciparum.

de Macedo CS, Uhrig ML, Kimura EA, Katzin AM.

FEMS Microbiol Lett. 2002 Jan 22;207(1):13-20.


Limonene arrests parasite development and inhibits isoprenylation of proteins in Plasmodium falciparum.

Moura IC, Wunderlich G, Uhrig ML, Couto AS, Peres VJ, Katzin AM, Kimura EA.

Antimicrob Agents Chemother. 2001 Sep;45(9):2553-8.


More on protein glycosylation in the malaria parasite.

Kimura EA, Katzin AM, Couto AS.

Parasitol Today. 2000 Jan;16(1):38-40. No abstract available.


Allelic diversity and antibody recognition of Plasmodium falciparum merozoite surface protein 1 during hypoendemic malaria transmission in the Brazilian amazon region.

Da Silveira LA, Dorta ML, Kimura EA, Katzin AM, Kawamoto F, Tanabe K, Ferreira MU.

Infect Immun. 1999 Nov;67(11):5906-16.


Allelic diversity at the merozoite surface protein-1 locus of Plasmodium falciparum in clinical isolates from the southwestern Brazilian Amazon.

Ferreira MU, Liu Q, Kaneko O, Kimura M, Tanabe K, Kimura EA, Katzin AM, Isomura S, Kawamoto F.

Am J Trop Med Hyg. 1998 Sep;59(3):474-80.


The IgG-subclass distribution of naturally acquired antibodies to Plasmodium falciparum, in relation to malaria exposure and severity.

Ferreira MU, Kimura EA, Katzin AM, Santos-Neto LL, Ferrari JO, Villalobos JM, de Carvalho ME.

Ann Trop Med Parasitol. 1998 Apr;92(3):245-56.


N-linked glycoproteins are related to schizogony of the intraerythrocytic stage in Plasmodium falciparum.

Kimura EA, Couto AS, Peres VJ, Casal OL, Katzin AM.

J Biol Chem. 1996 Jun 14;271(24):14452-61.


Non-phenolic method of DNA purification from bacteria, blood samples and other biological sources for restriction enzyme assays and the polymerase chain reaction.

Ikuta N, Kimura EA, Taque J, Lunge VR, Da Silva LP, Debes A, Ozaki LS.

Mem Inst Oswaldo Cruz. 1992 Oct-Dec;87(4):589-91. No abstract available.

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