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Items: 1 to 50 of 219

1.

A potential central role of Thaumarchaeota in N-Cycling in a semi-arid environment, Fort Stanton Cave, Snowy River passage, New Mexico, USA.

Kimble JC, Winter AS, Spilde MN, Sinsabaugh RL, Northup DE.

FEMS Microbiol Ecol. 2018 Nov 1;94(11). doi: 10.1093/femsec/fiy173.

PMID:
30165514
2.

C. elegans germ cells divide and differentiate in a folded tissue.

Seidel HS, Smith TA, Evans JK, Stamper JQ, Mast TG, Kimble J.

Dev Biol. 2018 Oct 1;442(1):173-187. doi: 10.1016/j.ydbio.2018.07.013. Epub 2018 Jul 19.

3.

An RNA-Binding Multimer Specifies Nematode Sperm Fate.

Aoki ST, Porter DF, Prasad A, Wickens M, Bingman CA, Kimble J.

Cell Rep. 2018 Jun 26;23(13):3769-3775. doi: 10.1016/j.celrep.2018.05.095.

4.

STAT4 is required for the generation of Th1 and Th2, but not Th17 immune responses during monophosphoryl lipid A adjuvant activity.

Varikuti S, Oghumu S, Natarajan G, Kimble J, Sperling RH, Moretti E, Kaplan MH, Satoskar AR.

Int Immunol. 2018 Jul 24;30(8):385. doi: 10.1093/intimm/dxy037. No abstract available.

5.

John Sulston (1942-2018).

Kimble J.

Science. 2018 Apr 13;360(6385):157. doi: 10.1126/science.aat6705. No abstract available.

PMID:
29650662
6.

SYGL-1 and LST-1 link niche signaling to PUF RNA repression for stem cell maintenance in Caenorhabditis elegans.

Shin H, Haupt KA, Kershner AM, Kroll-Conner P, Wickens M, Kimble J.

PLoS Genet. 2017 Dec 12;13(12):e1007121. doi: 10.1371/journal.pgen.1007121. eCollection 2017 Dec.

7.

STAT1 gene deficient mice develop accelerated breast cancer growth and metastasis which is reduced by IL-17 blockade.

Varikuti S, Oghumu S, Elbaz M, Volpedo G, Ahirwar DK, Alarcon PC, Sperling RH, Moretti E, Pioso MS, Kimble J, Nasser MW, Ganju RK, Terrazas C, Satoskar AR.

Oncoimmunology. 2017 Aug 14;6(11):e1361088. doi: 10.1080/2162402X.2017.1361088. eCollection 2017.

8.

Skin and fur bacterial diversity and community structure on American southwestern bats: effects of habitat, geography and bat traits.

Winter AS, Hathaway JJM, Kimble JC, Buecher DC, Valdez EW, Porras-Alfaro A, Young JM, Read KJH, Northup DE.

PeerJ. 2017 Oct 27;5:e3944. doi: 10.7717/peerj.3944. eCollection 2017.

9.

Ly6Chi inflammatory monocytes promote susceptibility to Leishmania donovani infection.

Terrazas C, Varikuti S, Oghumu S, Steinkamp HM, Ardic N, Kimble J, Nakhasi H, Satoskar AR.

Sci Rep. 2017 Oct 31;7(1):14693. doi: 10.1038/s41598-017-14935-3.

10.

Not just Salk.

Greider C, Hopkins N, Steitz J, Amon A, Asai D, Barres B, Bass B, Bassler B, Birgeneau R, Bjorkman P, Botchan M, Brugge J, Cech T, Colwell R, Craig N, deLange T, Eisen M, Gottesman S, Green R, Handelsman J, Kimble J, King MC, Lehmann R, Marder E, Mullins D, O'Shea E, Schmid S, Seydoux G, Spradling A, Storz G, Szostak J, Telesnitsky A, Tilghman S, Tjian R, Vale R, Wolberger C, Zakian V.

Science. 2017 Sep 15;357(6356):1105-1106. doi: 10.1126/science.aao6221. No abstract available.

PMID:
28912235
11.

C. elegans GLP-1/Notch activates transcription in a probability gradient across the germline stem cell pool.

Lee C, Sorensen EB, Lynch TR, Kimble J.

Elife. 2016 Oct 5;5. pii: e18370. doi: 10.7554/eLife.18370.

12.

STAT4 is required for the generation of Th1 and Th2, but not Th17 immune responses during monophosphoryl lipid A adjuvant activity.

Varikuti S, Oghumu S, Natarajan G, Kimble J, Sperling RH, Moretti E, Kaplan MH, Satoskar AR.

Int Immunol. 2016 Nov;28(11):565-570. Epub 2016 Aug 30.

13.

Analysis of the C. elegans Germline Stem Cell Pool.

Crittenden SL, Seidel HS, Kimble J.

Methods Mol Biol. 2017;1463:1-33.

PMID:
27734344
14.

The PUF binding landscape in metazoan germ cells.

Prasad A, Porter DF, Kroll-Conner PL, Mohanty I, Ryan AR, Crittenden SL, Wickens M, Kimble J.

RNA. 2016 Jul;22(7):1026-43. doi: 10.1261/rna.055871.116. Epub 2016 May 10.

15.

PGL germ granule assembly protein is a base-specific, single-stranded RNase.

Aoki ST, Kershner AM, Bingman CA, Wickens M, Kimble J.

Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1279-84. doi: 10.1073/pnas.1524400113. Epub 2016 Jan 19.

16.

IL-17A promotes susceptibility during experimental visceral leishmaniasis caused by Leishmania donovani.

Terrazas C, Varikuti S, Kimble J, Moretti E, Boyaka PN, Satoskar AR.

FASEB J. 2016 Mar;30(3):1135-43. doi: 10.1096/fj.15-277202. Epub 2015 Nov 18.

17.

Genomic Analyses of Sperm Fate Regulator Targets Reveal a Common Set of Oogenic mRNAs in Caenorhabditis elegans.

Noble DC, Aoki ST, Ortiz MA, Kim KW, Verheyden JM, Kimble J.

Genetics. 2016 Jan;202(1):221-34. doi: 10.1534/genetics.115.182592. Epub 2015 Nov 12.

18.

Cell-cycle quiescence maintains Caenorhabditis elegans germline stem cells independent of GLP-1/Notch.

Seidel HS, Kimble J.

Elife. 2015 Nov 9;4. pii: e10832. doi: 10.7554/eLife.10832.

19.

Embryonic Stem Cell Growth Factors Regulate eIF2α Phosphorylation.

Friend K, Brooks HA, Propson NE, Thomson JA, Kimble J.

PLoS One. 2015 Sep 25;10(9):e0139076. doi: 10.1371/journal.pone.0139076. eCollection 2015.

20.

NeuCode Labeling in Nematodes: Proteomic and Phosphoproteomic Impact of Ascaroside Treatment in Caenorhabditis elegans.

Rhoads TW, Prasad A, Kwiecien NW, Merrill AE, Zawack K, Westphall MS, Schroeder FC, Kimble J, Coon JJ.

Mol Cell Proteomics. 2015 Nov;14(11):2922-35. doi: 10.1074/mcp.M115.049684. Epub 2015 Sep 21.

21.

Strategies from UW-Madison for rescuing biomedical research in the US.

Kimble J, Bement WM, Chang Q, Cox BL, Drinkwater NR, Gourse RL, Hoskins AA, Huttenlocher A, Kreeger PK, Lambert PF, Mailick MR, Miyamoto S, Moss RL, O'Connor-Giles KM, Roopra A, Saha K, Seidel HS.

Elife. 2015 Jun 30;4:e09305. doi: 10.7554/eLife.09305.

22.

Signal transducer and activator of transcription 1 (STAT-1) plays a critical role in control of Trypanosoma cruzi infection.

Kulkarni MM, Varikuti S, Terrazas C, Kimble JL, Satoskar AR, McGwire BS.

Immunology. 2015 Jun;145(2):225-31. doi: 10.1111/imm.12438.

23.

CXCR3 expression defines a novel subset of innate CD8+ T cells that enhance immunity against bacterial infection and cancer upon stimulation with IL-15.

Oghumu S, Terrazas CA, Varikuti S, Kimble J, Vadia S, Yu L, Seveau S, Satoskar AR.

FASEB J. 2015 Mar;29(3):1019-28. doi: 10.1096/fj.14-264507. Epub 2014 Dec 2.

24.

Competence for chemical reprogramming of sexual fate correlates with an intersexual molecular signature in Caenorhabditis elegans.

Sorokin EP, Gasch AP, Kimble J.

Genetics. 2014 Oct;198(2):561-75. doi: 10.1534/genetics.114.169409. Epub 2014 Aug 21.

25.

A new dataset of spermatogenic vs. oogenic transcriptomes in the nematode Caenorhabditis elegans.

Ortiz MA, Noble D, Sorokin EP, Kimble J.

G3 (Bethesda). 2014 Jul 24;4(9):1765-72. doi: 10.1534/g3.114.012351.

26.

The physical activity energy cost of the latest active video games in young adults.

Howe CA, Barr MW, Winner BC, Kimble JR, White JB.

J Phys Act Health. 2015 Feb;12(2):171-7. doi: 10.1123/jpah.2013-0023. Epub 2014 Jun 5.

PMID:
24905451
27.

Comprehensive analysis of gene expression in human retina and supporting tissues.

Li M, Jia C, Kazmierkiewicz KL, Bowman AS, Tian L, Liu Y, Gupta NA, Gudiseva HV, Yee SS, Kim M, Dentchev T, Kimble JA, Parker JS, Messinger JD, Hakonarson H, Curcio CA, Stambolian D.

Hum Mol Genet. 2014 Aug 1;23(15):4001-14. doi: 10.1093/hmg/ddu114. Epub 2014 Mar 14.

PMID:
24634144
28.

A DTC niche plexus surrounds the germline stem cell pool in Caenorhabditis elegans.

Byrd DT, Knobel K, Affeldt K, Crittenden SL, Kimble J.

PLoS One. 2014 Feb 19;9(2):e88372. doi: 10.1371/journal.pone.0088372. eCollection 2014.

29.

Discovery of two GLP-1/Notch target genes that account for the role of GLP-1/Notch signaling in stem cell maintenance.

Kershner AM, Shin H, Hansen TJ, Kimble J.

Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3739-44. doi: 10.1073/pnas.1401861111. Epub 2014 Feb 24.

30.

C. elegans germline stem cells and their niche.

Kimble J, Seidel H.

StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008-.
2013 Nov 15.

31.

Alternative reassortment events leading to transmissible H9N1 influenza viruses in the ferret model.

Kimble JB, Angel M, Wan H, Sutton TC, Finch C, Perez DR.

J Virol. 2014 Jan;88(1):66-71. doi: 10.1128/JVI.02677-13. Epub 2013 Oct 16.

32.

Germline stem cells and their regulation in the nematode Caenorhabditis elegans.

Kershner A, Crittenden SL, Friend K, Sorensen EB, Porter DF, Kimble J.

Adv Exp Med Biol. 2013;786:29-46. doi: 10.1007/978-94-007-6621-1_3.

PMID:
23696350
33.

Mitosis-meiosis and sperm-oocyte fate decisions are separable regulatory events.

Morgan CT, Noble D, Kimble J.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3411-6. doi: 10.1073/pnas.1300928110. Epub 2013 Feb 11.

34.

In vivo selection of H1N2 influenza virus reassortants in the ferret model.

Angel M, Kimble JB, Pena L, Wan H, Perez DR.

J Virol. 2013 Mar;87(6):3277-83. doi: 10.1128/JVI.02591-12. Epub 2013 Jan 9.

35.

RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans.

LeGendre JB, Campbell ZT, Kroll-Conner P, Anderson P, Kimble J, Wickens M.

J Biol Chem. 2013 Jan 25;288(4):2532-45. doi: 10.1074/jbc.M112.397349. Epub 2012 Nov 29.

36.

The Ras-ERK MAPK regulatory network controls dedifferentiation in Caenorhabditis elegans germline.

Cha DS, Datla US, Hollis SE, Kimble J, Lee MH.

Biochim Biophys Acta. 2012 Oct;1823(10):1847-55. doi: 10.1016/j.bbamcr.2012.07.006. Epub 2012 Jul 20.

37.

A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality.

Buckley BA, Burkhart KB, Gu SG, Spracklin G, Kershner A, Fritz H, Kimble J, Fire A, Kennedy S.

Nature. 2012 Sep 20;489(7416):447-51. doi: 10.1038/nature11352. Epub 2012 Jul 18.

38.

C. elegans FOG-3/Tob can either promote or inhibit germline proliferation, depending on gene dosage and genetic context.

Snow JJ, Lee MH, Verheyden J, Kroll-Conner PL, Kimble J.

Oncogene. 2013 May 23;32(21):2614-21. doi: 10.1038/onc.2012.291. Epub 2012 Jul 16.

39.

mig-38, a novel gene that regulates distal tip cell turning during gonadogenesis in C. elegans hermaphrodites.

Martynovsky M, Wong MC, Byrd DT, Kimble J, Schwarzbauer JE.

Dev Biol. 2012 Aug 15;368(2):404-14. doi: 10.1016/j.ydbio.2012.06.011. Epub 2012 Jun 23.

40.

Identification of a conserved interface between PUF and CPEB proteins.

Campbell ZT, Menichelli E, Friend K, Wu J, Kimble J, Williamson JR, Wickens M.

J Biol Chem. 2012 May 25;287(22):18854-62. doi: 10.1074/jbc.M112.352815. Epub 2012 Apr 11.

41.

What does the concept of the stem cell niche really mean today?

Lander AD, Kimble J, Clevers H, Fuchs E, Montarras D, Buckingham M, Calof AL, Trumpp A, Oskarsson T.

BMC Biol. 2012 Mar 9;10:19. doi: 10.1186/1741-7007-10-19. No abstract available.

42.

A conserved PUF-Ago-eEF1A complex attenuates translation elongation.

Friend K, Campbell ZT, Cooke A, Kroll-Conner P, Wickens MP, Kimble J.

Nat Struct Mol Biol. 2012 Jan 8;19(2):176-83. doi: 10.1038/nsmb.2214.

43.

Divergence of Pumilio/fem-3 mRNA binding factor (PUF) protein specificity through variations in an RNA-binding pocket.

Qiu C, Kershner A, Wang Y, Holley CP, Wilinski D, Keles S, Kimble J, Wickens M, Hall TM.

J Biol Chem. 2012 Feb 24;287(9):6949-57. doi: 10.1074/jbc.M111.326264. Epub 2011 Dec 28.

44.

The oogenic germline starvation response in C. elegans.

Seidel HS, Kimble J.

PLoS One. 2011;6(12):e28074. doi: 10.1371/journal.pone.0028074. Epub 2011 Dec 2.

45.

Quantification of fluorescein-stained drusen associated with age-related macular degeneration.

Friedman D, Parker JS, Kimble JA, Delori FC, McGwin G Jr, Curcio CA.

Retina. 2012 Jan;32(1):19-24. doi: 10.1097/IAE.0b013e318219e5e9.

46.

Compatibility of H9N2 avian influenza surface genes and 2009 pandemic H1N1 internal genes for transmission in the ferret model.

Kimble JB, Sorrell E, Shao H, Martin PL, Perez DR.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12084-8. doi: 10.1073/pnas.1108058108. Epub 2011 Jul 5.

47.

Retinal pigment epithelial expression of complement regulator CD46 is altered early in the course of geographic atrophy.

Vogt SD, Curcio CA, Wang L, Li CM, McGwin G Jr, Medeiros NE, Philp NJ, Kimble JA, Read RW.

Exp Eye Res. 2011 Oct;93(4):413-23. doi: 10.1016/j.exer.2011.06.002. Epub 2011 Jun 12.

48.

Molecular regulation of the mitosis/meiosis decision in multicellular organisms.

Kimble J.

Cold Spring Harb Perspect Biol. 2011 Aug 1;3(8):a002683. doi: 10.1101/cshperspect.a002683. Review.

49.

Phosphorylation state of a Tob/BTG protein, FOG-3, regulates initiation and maintenance of the Caenorhabditis elegans sperm fate program.

Lee MH, Kim KW, Morgan CT, Morgan DE, Kimble J.

Proc Natl Acad Sci U S A. 2011 May 31;108(22):9125-30. doi: 10.1073/pnas.1106027108. Epub 2011 May 12.

50.

The impact of mitotic versus interphase chromatin architecture on the molecular flow of EGFP by pair correlation analysis.

Hinde E, Cardarelli F, Digman MA, Kershner A, Kimble J, Gratton E.

Biophys J. 2011 Apr 6;100(7):1829-36. doi: 10.1016/j.bpj.2011.02.024.

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