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Items: 1 to 50 of 105

1.

Enhanced chondrogenesis from human embryonic stem cells.

Wang T, Nimkingratana P, Smith CA, Cheng A, Hardingham TE, Kimber SJ.

Stem Cell Res. 2019 Aug;39:101497. doi: 10.1016/j.scr.2019.101497. Epub 2019 Jul 9.

2.

The role of Trp53 in the mouse embryonic response to DNA damage.

Wilson Y, Morris ID, Kimber SJ, Brison DR.

Mol Hum Reprod. 2019 Jul 1;25(7):397-407. doi: 10.1093/molehr/gaz029.

PMID:
31227838
3.

Establishment of porcine and human expanded potential stem cells.

Gao X, Nowak-Imialek M, Chen X, Chen D, Herrmann D, Ruan D, Chen ACH, Eckersley-Maslin MA, Ahmad S, Lee YL, Kobayashi T, Ryan D, Zhong J, Zhu J, Wu J, Lan G, Petkov S, Yang J, Antunes L, Campos LS, Fu B, Wang S, Yong Y, Wang X, Xue SG, Ge L, Liu Z, Huang Y, Nie T, Li P, Wu D, Pei D, Zhang Y, Lu L, Yang F, Kimber SJ, Reik W, Zou X, Shang Z, Lai L, Surani A, Tam PPL, Ahmed A, Yeung WSB, Teichmann SA, Niemann H, Liu P.

Nat Cell Biol. 2019 Jun;21(6):687-699. doi: 10.1038/s41556-019-0333-2. Epub 2019 Jun 3.

PMID:
31160711
4.

Characterisation of Osteopontin in an In Vitro Model of Embryo Implantation.

Berneau SC, Ruane PT, Brison DR, Kimber SJ, Westwood M, Aplin JD.

Cells. 2019 May 9;8(5). pii: E432. doi: 10.3390/cells8050432.

5.

Investigating the role of CD44 and hyaluronate in embryo-epithelial interaction using an in vitro model.

Berneau SC, Ruane PT, Brison DR, Kimber SJ, Westwood M, Aplin JD.

Mol Hum Reprod. 2019 May 1;25(5):265-273. doi: 10.1093/molehr/gaz011.

PMID:
30865276
6.

Systems based analysis of human embryos and gene networks involved in cell lineage allocation.

Smith HL, Stevens A, Minogue B, Sneddon S, Shaw L, Wood L, Adeniyi T, Xiao H, Lio P, Kimber SJ, Brison DR.

BMC Genomics. 2019 Mar 5;20(1):171. doi: 10.1186/s12864-019-5558-8.

7.

From human pluripotent stem cells to functional kidney organoids and models of renal disease.

Kimber SJ, Woolf AS.

Stem Cell Investig. 2018 Jul 21;5:20. doi: 10.21037/sci.2018.07.02. eCollection 2018. No abstract available.

8.

Osmotic stress induces JNK-dependent embryo invasion in a model of implantation.

Ruane PT, Koeck R, Berneau SC, Kimber SJ, Westwood M, Brison DR, Aplin JD.

Reproduction. 2018 Oct 16;156(5):421-428. doi: 10.1530/REP-18-0154.

PMID:
30131400
9.

Generation of Functioning Nephrons by Implanting Human Pluripotent Stem Cell-Derived Kidney Progenitors.

Bantounas I, Ranjzad P, Tengku F, Silajdžić E, Forster D, Asselin MC, Lewis P, Lennon R, Plagge A, Wang Q, Woolf AS, Kimber SJ.

Stem Cell Reports. 2018 Mar 13;10(3):766-779. doi: 10.1016/j.stemcr.2018.01.008. Epub 2018 Feb 8.

10.

Recombinant Extracellular Matrix Protein Fragments Support Human Embryonic Stem Cell Chondrogenesis.

Cheng A, Cain SA, Tian P, Baldwin AK, Uppanan P, Kielty CM, Kimber SJ.

Tissue Eng Part A. 2018 Jun;24(11-12):968-978. doi: 10.1089/ten.TEA.2017.0285. Epub 2018 Feb 7.

11.

Integrin and FAK Regulation of Human Pluripotent Stem Cells.

Vitillo L, Kimber SJ.

Curr Stem Cell Rep. 2017;3(4):358-365. doi: 10.1007/s40778-017-0100-x. Epub 2017 Oct 13. Review.

12.

Apposition to endometrial epithelial cells activates mouse blastocysts for implantation.

Ruane PT, Berneau SC, Koeck R, Watts J, Kimber SJ, Brison DR, Westwood M, Aplin JD.

Mol Hum Reprod. 2017 Sep 1;23(9):617-627. doi: 10.1093/molehr/gax043.

PMID:
28911212
13.

PTHrP is essential for normal morphogenetic and functional development of the murine placenta.

Duval C, Dilworth MR, Tunster SJ, Kimber SJ, Glazier JD.

Dev Biol. 2017 Oct 15;430(2):325-336. doi: 10.1016/j.ydbio.2017.08.033. Epub 2017 Aug 31. No abstract available.

14.

High quality clinical grade human embryonic stem cell lines derived from fresh discarded embryos.

Ye J, Bates N, Soteriou D, Grady L, Edmond C, Ross A, Kerby A, Lewis PA, Adeniyi T, Wright R, Poulton KV, Lowe M, Kimber SJ, Brison DR.

Stem Cell Res Ther. 2017 Jun 5;8(1):128. doi: 10.1186/s13287-017-0561-y.

15.

LEF1-mediated MMP13 gene expression is repressed by SIRT1 in human chondrocytes.

Elayyan J, Lee EJ, Gabay O, Smith CA, Qiq O, Reich E, Mobasheri A, Henrotin Y, Kimber SJ, Dvir-Ginzberg M.

FASEB J. 2017 Jul;31(7):3116-3125. doi: 10.1096/fj.201601253R. Epub 2017 Apr 7. Erratum in: FASEB J. 2018 Dec;32(12):7028.

16.

Integrin-Associated Focal Adhesion Kinase Protects Human Embryonic Stem Cells from Apoptosis, Detachment, and Differentiation.

Vitillo L, Baxter M, Iskender B, Whiting P, Kimber SJ.

Stem Cell Reports. 2016 Aug 9;7(2):167-76. doi: 10.1016/j.stemcr.2016.07.006.

17.

Corrigendum: Graphene Oxide promotes embryonic stem cell differentiation to haematopoietic lineage.

Garcia-Alegria E, Iliut M, Stefanska M, Silva C, Heeg S, Kimber SJ, Kouskoff V, Lacaud G, Vijayaraghavan A, Batta K.

Sci Rep. 2016 Jul 4;6:28723. doi: 10.1038/srep28723. No abstract available.

18.

Graphene Oxide promotes embryonic stem cell differentiation to haematopoietic lineage.

Garcia-Alegria E, Iliut M, Stefanska M, Silva C, Heeg S, Kimber SJ, Kouskoff V, Lacaud G, Vijayaraghavan A, Batta K.

Sci Rep. 2016 May 20;6:25917. doi: 10.1038/srep25917. Erratum in: Sci Rep. 2016 Jul 04;6:28723.

19.

Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived Hepatocytes.

Cameron K, Tan R, Schmidt-Heck W, Campos G, Lyall MJ, Wang Y, Lucendo-Villarin B, Szkolnicka D, Bates N, Kimber SJ, Hengstler JG, Godoy P, Forbes SJ, Hay DC.

Stem Cell Reports. 2015 Dec 8;5(6):1250-1262. doi: 10.1016/j.stemcr.2015.10.016. Epub 2015 Nov 25.

20.

The Molecular Karyotype of 25 Clinical-Grade Human Embryonic Stem Cell Lines.

Canham MA, Van Deusen A, Brison DR, De Sousa PA, Downie J, Devito L, Hewitt ZA, Ilic D, Kimber SJ, Moore HD, Murray H, Kunath T.

Sci Rep. 2015 Nov 26;5:17258. doi: 10.1038/srep17258.

21.

Polyurethane: Stable Cell Phenotype Requires Plasticity: Polymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance (Adv. Healthcare Mater. 12/2015).

Villarin BL, Cameron K, Szkolnicka D, Rashidi H, Bates N, Kimber SJ, Flint O, Forbes SJ, Iredale JP, Bradley M, Hay DC.

Adv Healthc Mater. 2015 Aug 26;4(12):1819. doi: 10.1002/adhm.201570072.

PMID:
26308957
22.

Proteomic analysis of integrin-associated complexes from mesenchymal stem cells.

Ajeian JN, Horton ER, Astudillo P, Byron A, Askari JA, Millon-Frémillon A, Knight D, Kimber SJ, Humphries MJ, Humphries JD.

Proteomics Clin Appl. 2016 Jan;10(1):51-7. doi: 10.1002/prca.201500033. Epub 2015 Sep 17.

23.

Polymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance.

Villarin BL, Cameron K, Szkolnicka D, Rashidi H, Bates N, Kimber SJ, Flint O, Forbes SJ, Iredale JP, Bradley M, Hay DC.

Adv Healthc Mater. 2015 Aug 26;4(12):1820-5. doi: 10.1002/adhm.201500391. Epub 2015 Jun 24.

24.

Maternal nutrition modifies trophoblast giant cell phenotype and fetal growth in mice.

Watkins AJ, Lucas ES, Marfy-Smith S, Bates N, Kimber SJ, Fleming TP.

Reproduction. 2015 Jun;149(6):563-75. doi: 10.1530/REP-14-0667. Epub 2015 Mar 9.

25.

MiR-145 suppresses embryo-epithelial juxtacrine communication at implantation by modulating maternal IGF1R.

Kang YJ, Lees M, Matthews LC, Kimber SJ, Forbes K, Aplin JD.

J Cell Sci. 2015 Feb 15;128(4):804-14. doi: 10.1242/jcs.164004. Epub 2015 Jan 20.

26.

Cartilage repair using human embryonic stem cell-derived chondroprogenitors.

Cheng A, Kapacee Z, Peng J, Lu S, Lucas RJ, Hardingham TE, Kimber SJ.

Stem Cells Transl Med. 2014 Nov;3(11):1287-94. doi: 10.5966/sctm.2014-0101. Epub 2014 Oct 1.

27.

How should we assess the safety of IVF technologies?

Brison DR, Roberts SA, Kimber SJ.

Reprod Biomed Online. 2013 Dec;27(6):710-21. doi: 10.1016/j.rbmo.2013.09.006. Epub 2013 Sep 14. Review.

PMID:
24145118
28.

Generating cartilage repair from pluripotent stem cells.

Cheng A, Hardingham TE, Kimber SJ.

Tissue Eng Part B Rev. 2014 Aug;20(4):257-66. doi: 10.1089/ten.TEB.2012.0757. Epub 2013 Sep 24. Review.

29.

Global gene expression profiling of individual human oocytes and embryos demonstrates heterogeneity in early development.

Shaw L, Sneddon SF, Zeef L, Kimber SJ, Brison DR.

PLoS One. 2013 May 22;8(5):e64192. doi: 10.1371/journal.pone.0064192. Print 2013.

30.

Chondrocyte protocol.

Oldershaw RA, Baxter MA, Lowe ET, Bates N, Grady LM, Soncin F, Brison DR, Hardingham TE, Kimber SJ.

StemBook [Internet]. Cambridge (MA): Harvard Stem Cell Institute; 2008-.
2012 Jun 10.

31.

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

Soteriou D, Iskender B, Byron A, Humphries JD, Borg-Bartolo S, Haddock MC, Baxter MA, Knight D, Humphries MJ, Kimber SJ.

J Biol Chem. 2013 Jun 28;288(26):18716-31. doi: 10.1074/jbc.M113.463372. Epub 2013 May 8.

32.

Comparison of gene expression in fresh and frozen-thawed human preimplantation embryos.

Shaw L, Sneddon SF, Brison DR, Kimber SJ.

Reproduction. 2012 Nov;144(5):569-82. doi: 10.1530/REP-12-0047. Epub 2012 Sep 20.

PMID:
22996807
33.

Human feeder cell line for derivation and culture of hESc/hiPSc.

McKay TR, Camarasa MV, Iskender B, Ye J, Bates N, Miller D, Fitzsimmons JC, Foxler D, Mee M, Sharp TV, Aplin J, Brison DR, Kimber SJ.

Stem Cell Res. 2011 Sep;7(2):154-62. doi: 10.1016/j.scr.2011.04.005. Epub 2011 May 16.

34.

Sox2 is essential for formation of trophectoderm in the preimplantation embryo.

Keramari M, Razavi J, Ingman KA, Patsch C, Edenhofer F, Ward CM, Kimber SJ.

PLoS One. 2010 Nov 12;5(11):e13952. doi: 10.1371/journal.pone.0013952.

35.

Directed differentiation of human embryonic stem cells toward chondrocytes.

Oldershaw RA, Baxter MA, Lowe ET, Bates N, Grady LM, Soncin F, Brison DR, Hardingham TE, Kimber SJ.

Nat Biotechnol. 2010 Nov;28(11):1187-94. doi: 10.1038/nbt.1683. Epub 2010 Oct 22.

PMID:
20967028
36.

Gene expression analysis of a new source of human oocytes and embryos for research and human embryonic stem cell derivation.

Sneddon SF, DeSousa PA, Arnesen RE, Lieberman BA, Kimber SJ, Brison DR.

Fertil Steril. 2011 Mar 15;95(4):1410-5. doi: 10.1016/j.fertnstert.2010.08.050. Epub 2010 Oct 6.

PMID:
20926071
37.

Early stages of implantation as revealed by an in vitro model.

Singh H, Nardo L, Kimber SJ, Aplin JD.

Reproduction. 2010 May;139(5):905-14. doi: 10.1530/REP-09-0271. Epub 2010 Feb 23.

PMID:
20179188
38.

Derivation of Man-1 and Man-2 research grade human embryonic stem cell lines.

Camarasa MV, Kerr RW, Sneddon SF, Bates N, Shaw L, Oldershaw RA, Small F, Baxter MA, Mckay TR, Brison DR, Kimber SJ.

In Vitro Cell Dev Biol Anim. 2010 Apr;46(3-4):386-94. doi: 10.1007/s11626-010-9291-5. Epub 2010 Feb 23.

PMID:
20177994
39.

Gene expression profiling of the developing mouse kidney and embryo.

Shaw L, Johnson PA, Kimber SJ.

In Vitro Cell Dev Biol Anim. 2010 Feb;46(2):155-65. doi: 10.1007/s11626-009-9254-x. Epub 2009 Dec 9.

PMID:
19998061
40.

Genes and signals regulating murine trophoblast cell development.

El-Hashash AH, Warburton D, Kimber SJ.

Mech Dev. 2010 Jan-Feb;127(1-2):1-20. doi: 10.1016/j.mod.2009.09.004. Epub 2009 Sep 13. Review.

41.

Determining the LIF-sensitive period for implantation using a LIF-receptor antagonist.

Mohamet L, Heath JK, Kimber SJ.

Reproduction. 2009 Nov;138(5):827-36. doi: 10.1530/REP-09-0113. Epub 2009 Jul 27.

PMID:
19635738
42.

Naturally immortalised mouse embryonic fibroblast lines support human embryonic stem cell growth.

Camarasa M, Brison D, Kimber SJ, Handyside AH.

Cloning Stem Cells. 2009 Sep;11(3):453-62. doi: 10.1089/clo.2008.0082.

PMID:
19594387
43.

Analysis of the distinct functions of growth factors and tissue culture substrates necessary for the long-term self-renewal of human embryonic stem cell lines.

Baxter MA, Camarasa MV, Bates N, Small F, Murray P, Edgar D, Kimber SJ.

Stem Cell Res. 2009 Jul;3(1):28-38. doi: 10.1016/j.scr.2009.03.002. Epub 2009 Apr 5.

44.

Clinically failed eggs as a source of normal human embryo stem cells.

De Sousa PA, Gardner J, Sneddon S, Pells S, Tye BJ, Dand P, Collins DM, Stewart K, Shaw L, Przyborski S, Cooke M, McLaughlin KJ, Kimber SJ, Lieberman BA, Wilmut I, Brison DR.

Stem Cell Res. 2009 May;2(3):188-97. doi: 10.1016/j.scr.2009.01.002. Epub 2009 Feb 6.

45.

Expression of genes involved in early cell fate decisions in human embryos and their regulation by growth factors.

Kimber SJ, Sneddon SF, Bloor DJ, El-Bareg AM, Hawkhead JA, Metcalfe AD, Houghton FD, Leese HJ, Rutherford A, Lieberman BA, Brison DR.

Reproduction. 2008 May;135(5):635-47. doi: 10.1530/REP-07-0359.

PMID:
18411410
46.

Interleukin 1 signaling is regulated by leukemia inhibitory factor (LIF) and is aberrant in Lif-/- mouse uterus.

Fouladi-Nashta AA, Mohamet L, Heath JK, Kimber SJ.

Biol Reprod. 2008 Jul;79(1):142-53. doi: 10.1095/biolreprod.107.065219. Epub 2008 Mar 12.

PMID:
18337516
47.
48.
49.

Leukaemia inhibitory factor in implantation and uterine biology.

Kimber SJ.

Reproduction. 2005 Aug;130(2):131-45. Review.

PMID:
16049151

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