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Formation Mechanism and Gram-Scale Production of PtNi Hollow Nanoparticles for Oxygen Electrocatalysis through In Situ Galvanic Displacement Reaction.

Kang YS, Jung JY, Choi D, Sohn Y, Lee SH, Lee KS, Kim ND, Kim P, Yoo SJ.

ACS Appl Mater Interfaces. 2020 Mar 24. doi: 10.1021/acsami.9b22615. [Epub ahead of print]


Are Households in Kiribati Nutrition Secure? A Case Study of South Tarawa and Butaritari.

Eme PE, Kim ND, Douwes J, Burlingame B, Foliaki S, Wham C.

Food Nutr Bull. 2020 Mar;41(1):131-146. doi: 10.1177/0379572119891024. Epub 2020 Feb 12.


Identification of a Unique Resorcylic Acid Lactone Derivative That Targets Both Lymphangiogenesis and Angiogenesis.

Han Y, Sengupta S, Lee BJ, Cho H, Kim J, Choi HG, Dash U, Kim JH, Kim ND, Kim JH, Sim T.

J Med Chem. 2019 Oct 24;62(20):9141-9160. doi: 10.1021/acs.jmedchem.9b01025. Epub 2019 Oct 7.


Identification of Novel Resorcinol Amide Derivatives as Potent and Specific Pyruvate Dehydrogenase Kinase (PDHK) Inhibitors.

Cho H, Shin I, Cho K, Yoon H, Yoo EK, Kim MJ, Park S, Lee IK, Kim ND, Sim T.

J Med Chem. 2019 Sep 26;62(18):8461-8479. doi: 10.1021/acs.jmedchem.9b00565. Epub 2019 Sep 13.


Pro-apoptotic effect of the novel benzylidene derivative MHY695 in human colon cancer cells.

Heo G, Kang D, Park C, Kim SJ, Choo J, Lee Y, Yoo JW, Jung Y, Lee J, Kim ND, Chung HY, Moon HR, Im E.

Oncol Lett. 2019 Sep;18(3):3256-3264. doi: 10.3892/ol.2019.10664. Epub 2019 Jul 25.


Characterization of Oncolytic Vaccinia Virus Harboring the Human IFNB1 and CES2 Transgenes.

Cho E, Islam SMBU, Jiang F, Park JE, Lee B, Kim ND, Hwang TH.

Cancer Res Treat. 2020 Jan;52(1):309-319. doi: 10.4143/crt.2019.161. Epub 2019 Aug 6.


An Inhibitor of the Interaction of Survivin with Smac in Mitochondria Promotes Apoptosis.

Park SH, Shin I, Park SH, Kim ND, Shin I.

Chem Asian J. 2019 Nov 18;14(22):4035-4041. doi: 10.1002/asia.201900587. Epub 2019 Jul 24.


Synthesis and structure activity relationships of a series of 4-amino-1H-pyrazoles as covalent inhibitors of CDK14.

Ferguson FM, Doctor ZM, Ficarro SB, Marto JA, Kim ND, Sim T, Gray NS.

Bioorg Med Chem Lett. 2019 Aug 1;29(15):1985-1993. doi: 10.1016/j.bmcl.2019.05.024. Epub 2019 May 23.


PKM2 Knockdown Induces Autophagic Cell Death via AKT/mTOR Pathway in Human Prostate Cancer Cells.

Dey P, Kundu A, Sachan R, Park JH, Ahn MY, Yoon K, Lee J, Kim ND, Kim IS, Lee BM, Kim HS.

Cell Physiol Biochem. 2019;52(6):1535-1552. doi: 10.33594/000000107.


Redefining Chronic Inflammation in Aging and Age-Related Diseases: Proposal of the Senoinflammation Concept.

Chung HY, Kim DH, Lee EK, Chung KW, Chung S, Lee B, Seo AY, Chung JH, Jung YS, Im E, Lee J, Kim ND, Choi YJ, Im DS, Yu BP.

Aging Dis. 2019 Apr 1;10(2):367-382. doi: 10.14336/AD.2018.0324. eCollection 2019 Apr. Review.


Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome.

Rao S, Gurbani D, Du G, Everley RA, Browne CM, Chaikuad A, Tan L, Schröder M, Gondi S, Ficarro SB, Sim T, Kim ND, Berberich MJ, Knapp S, Marto JA, Westover KD, Sorger PK, Gray NS.

Cell Chem Biol. 2019 Jun 20;26(6):818-829.e9. doi: 10.1016/j.chembiol.2019.02.021. Epub 2019 Apr 11.


Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity.

Ferguson FM, Doctor ZM, Ficarro SB, Browne CM, Marto JA, Johnson JL, Yaron TM, Cantley LC, Kim ND, Sim T, Berberich MJ, Kalocsay M, Sorger PK, Gray NS.

Cell Chem Biol. 2019 Jun 20;26(6):804-817.e12. doi: 10.1016/j.chembiol.2019.02.015. Epub 2019 Mar 28.


Morin enhances auranofin anticancer activity by up-regulation of DR4 and DR5 and modulation of Bcl-2 through reactive oxygen species generation in Hep3B human hepatocellular carcinoma cells.

Hwang-Bo H, Lee WS, Nagappan A, Kim HJ, Panchanathan R, Park C, Chang SH, Kim ND, Leem SH, Chang YC, Kwon TK, Cheong JH, Kim GS, Jung JM, Shin SC, Hong SC, Choi YH.

Phytother Res. 2019 May;33(5):1384-1393. doi: 10.1002/ptr.6329. Epub 2019 Mar 19.


Myricetin Protects Against High Glucose-Induced β-Cell Apoptosis by Attenuating Endoplasmic Reticulum Stress via Inactivation of Cyclin-Dependent Kinase 5.

Karunakaran U, Elumalai S, Moon JS, Jeon JH, Kim ND, Park KG, Won KC, Leem J, Lee IK.

Diabetes Metab J. 2019 Apr;43(2):192-205. doi: 10.4093/dmj.2018.0052. Epub 2019 Jan 16.


Roles of folate in skeletal muscle cell development and functions.

Hwang SY, Sung B, Kim ND.

Arch Pharm Res. 2019 Apr;42(4):319-325. doi: 10.1007/s12272-018-1100-9. Epub 2019 Jan 1. Review.


MHY440, a Novel Topoisomerase Ι Inhibitor, Induces Cell Cycle Arrest and Apoptosis via a ROS-Dependent DNA Damage Signaling Pathway in AGS Human Gastric Cancer Cells.

Jang JY, Kang YJ, Sung B, Kim MJ, Park C, Kang D, Moon HR, Chung HY, Kim ND.

Molecules. 2018 Dec 28;24(1). pii: E96. doi: 10.3390/molecules24010096.


Facile in Situ Synthesis of Multiple-Heteroatom-Doped Carbons Derived from Polyimide Precursors for Flexible All-Solid-State Supercapacitors.

Kim DK, Bong S, Jin X, Seong KD, Hwang M, Kim ND, You NH, Piao Y.

ACS Appl Mater Interfaces. 2019 Jan 16;11(2):1996-2005. doi: 10.1021/acsami.8b15162. Epub 2019 Jan 3.


Inhibitory Effects of 2N1HIA (2-(3-(2-Fluoro-4-Methoxyphenyl)-6-Oxo-1(6H)-Pyridazinyl)-N-1H-Indol-5-Ylacetamide) on Osteoclast Differentiation via Suppressing Cathepsin K Expression.

Ahn SH, Chen Z, Lee J, Lee SW, Min SH, Kim ND, Lee TH.

Molecules. 2018 Nov 29;23(12). pii: E3139. doi: 10.3390/molecules23123139.


BCPA {N,N'-1,4-Butanediylbis[3-(2-chlorophenyl)acrylamide]} Inhibits Osteoclast Differentiation through Increased Retention of Peptidyl-Prolyl cis-trans Isomerase Never in Mitosis A-Interacting 1.

Cho E, Lee JK, Lee JY, Chen Z, Ahn SH, Kim ND, Kook MS, Min SH, Park BJ, Lee TH.

Int J Mol Sci. 2018 Nov 1;19(11). pii: E3436. doi: 10.3390/ijms19113436.


First SAR Study for Overriding NRAS Mutant Driven Acute Myeloid Leukemia.

Cho H, Shin I, Ju E, Choi S, Hur W, Kim H, Hong E, Kim ND, Choi HG, Gray NS, Sim T.

J Med Chem. 2018 Sep 27;61(18):8353-8373. doi: 10.1021/acs.jmedchem.8b00882. Epub 2018 Sep 11.


Preclinical safety evaluation of hepatic arterial infusion of oncolytic poxvirus.

Cho E, Ryu EJ, Jiang F, Jeon UB, Cho M, Kim CH, Kim M, Kim ND, Hwang TH.

Drug Des Devel Ther. 2018 Aug 8;12:2467-2474. doi: 10.2147/DDDT.S171269. eCollection 2018.


Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains.

Wang J, Erazo T, Ferguson FM, Buckley DL, Gomez N, Muñoz-Guardiola P, Diéguez-Martínez N, Deng X, Hao M, Massefski W, Fedorov O, Offei-Addo NK, Park PM, Dai L, DiBona A, Becht K, Kim ND, McKeown MR, Roberts JM, Zhang J, Sim T, Alessi DR, Bradner JE, Lizcano JM, Blacklow SC, Qi J, Xu X, Gray NS.

ACS Chem Biol. 2018 Sep 21;13(9):2438-2448. doi: 10.1021/acschembio.7b00638. Epub 2018 Aug 31.


Oligodendrocytic but not neuronal Nogo restricts corticospinal axon sprouting after CNS injury.

Meves JM, Geoffroy CG, Kim ND, Kim JJ, Zheng B.

Exp Neurol. 2018 Nov;309:32-43. doi: 10.1016/j.expneurol.2018.07.013. Epub 2018 Jul 25.


DPIE [2-(1,2-diphenyl-1H-indol-3-yl)ethanamine] Augments Pro-Inflammatory Cytokine Production in IL-1β-Stimulated Primary Human Oral Cells.

Ahn SH, Lee JK, Kim ND, Kim SH, Lee S, Jung S, Chay KO, Lee TH.

Int J Mol Sci. 2018 Jun 22;19(7). pii: E1835. doi: 10.3390/ijms19071835.


Discovery of a novel potent peptide agonist to adiponectin receptor 1.

Kim S, Lee Y, Kim JW, Son YJ, Ma MJ, Um JH, Kim ND, Min SH, Kim DI, Kim BB.

PLoS One. 2018 Jun 18;13(6):e0199256. doi: 10.1371/journal.pone.0199256. eCollection 2018.


15-Deoxy-Δ12,14-prostaglandin J2 activates PI3K-Akt signaling in human breast cancer cells through covalent modification of the tumor suppressor PTEN at cysteine 136.

Suh J, Kim DH, Kim EH, Park SA, Park JM, Jang JH, Kim SJ, Na HK, Kim ND, Kim NJ, Suh YG, Surh YJ.

Cancer Lett. 2018 Jun 28;424:30-45. doi: 10.1016/j.canlet.2018.03.016. Epub 2018 Mar 14.


Induction of apoptosis by ethanol extract of Citrus unshiu Markovich peel in human bladder cancer T24 cells through ROS-mediated inactivation of the PI3K/Akt pathway.

Ahn KI, Choi EO, Kwon DH, HwangBo H, Kim MY, Kim HJ, Ji SY, Hong SH, Jeong JW, Park C, Kim ND, Kim WJ, Choi YH.

Biosci Trends. 2017 Nov 20;11(5):565-573. doi: 10.5582/bst.2017.01218. Epub 2017 Oct 24.


A small-molecule inhibitor targeting the AURKC-IκBα interaction decreases transformed growth of MDA-MB-231 breast cancer cells.

Han EH, Min JY, Yoo SA, Park SJ, Choe YJ, Yun HS, Lee ZW, Jin SW, Kim HG, Jeong HG, Kim HK, Kim ND, Chung YH.

Oncotarget. 2017 Jun 29;8(41):69691-69708. doi: 10.18632/oncotarget.18883. eCollection 2017 Sep 19.


Transformation of liver cells by 3-methylcholanthrene potentiates oxidative stress via the downregulation of glutathione synthesis.

Kim SH, Yoon D, Lee YH, Lee J, Kim ND, Kim S, Jung YS.

Int J Mol Med. 2017 Dec;40(6):2011-2017. doi: 10.3892/ijmm.2017.3184. Epub 2017 Oct 11.


Structurally Engineered Nanoporous Ta2O5-x Selector-Less Memristor for High Uniformity and Low Power Consumption.

Kwon S, Kim TW, Jang S, Lee JH, Kim ND, Ji Y, Lee CH, Tour JM, Wang G.

ACS Appl Mater Interfaces. 2017 Oct 4;9(39):34015-34023. doi: 10.1021/acsami.7b06918. Epub 2017 Sep 19.


Characterization of a highly selective inhibitor of the Aurora kinases.

Ferguson FM, Doctor ZM, Chaikuad A, Sim T, Kim ND, Knapp S, Gray NS.

Bioorg Med Chem Lett. 2017 Sep 15;27(18):4405-4408. doi: 10.1016/j.bmcl.2017.08.016. Epub 2017 Aug 10.


MHY451 induces cell cycle arrest and apoptosis by ROS generation in HCT116 human colorectal cancer cells.

Hwang NL, Kang YJ, Sung B, Hwang SY, Jang JY, Oh HJ, Ahn YR, Kim DH, Kim SJ, Ullah S, Hossain MA, Moon HR, Chung HY, Kim ND.

Oncol Rep. 2017 Sep;38(3):1783-1789. doi: 10.3892/or.2017.5836. Epub 2017 Jul 18.


The Application of REDOR NMR to Understand the Conformation of Epothilone B.

Lee JH, Kim MS, Lee HW, Lee IC, Kim HK, Kim ND, Lee S, Seo H, Paik Y.

Int J Mol Sci. 2017 Jul 9;18(7). pii: E1472. doi: 10.3390/ijms18071472.


HS-1793, a resveratrol analogue, downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model.

Kim DH, Sung B, Kim JA, Kang YJ, Hwang SY, Hwang NL, Suh H, Choi YH, Im E, Chung HY, Kim ND.

Int J Oncol. 2017 Aug;51(2):715-723. doi: 10.3892/ijo.2017.4058. Epub 2017 Jun 27.


Complement C5a Receptor is the Key Initiator of Neutrophil Adhesion Igniting Immune Complex-induced Arthritis.

Miyabe Y, Miyabe C, Murooka TT, Kim EY, Newton GA, Kim ND, Haribabu B, Luscinskas FW, Mempel TR, Luster AD.

Sci Immunol. 2017 Jan;2(7). pii: eaaj2195. doi: 10.1126/sciimmunol.aaj2195. Epub 2017 Jan 20.


Lithium Batteries with Nearly Maximum Metal Storage.

Raji AO, Villegas Salvatierra R, Kim ND, Fan X, Li Y, Silva GAL, Sha J, Tour JM.

ACS Nano. 2017 Jun 27;11(6):6362-6369. doi: 10.1021/acsnano.7b02731. Epub 2017 May 19.


Folic acid is necessary for proliferation and differentiation of C2C12 myoblasts.

Hwang SY, Kang YJ, Sung B, Jang JY, Hwang NL, Oh HJ, Ahn YR, Kim HJ, Shin JH, Yoo MA, Kim CM, Chung HY, Kim ND.

J Cell Physiol. 2018 Feb;233(2):736-747. doi: 10.1002/jcp.25989. Epub 2017 Jun 7.


Improved Hydrolysis of Organophosphorus Compounds by Engineered Human Prolidases.

Yun H, Lee S, Kim S, Yu J, Lee N, Lee J, Kim ND, Yu C, Rho J.

Protein Pept Lett. 2017;24(7):617-625. doi: 10.2174/0929866524666170428143759.


Graphene Carbon Nanotube Carpets Grown Using Binary Catalysts for High-Performance Lithium-Ion Capacitors.

Salvatierra RV, Zakhidov D, Sha J, Kim ND, Lee SK, Raji AO, Zhao N, Tour JM.

ACS Nano. 2017 Mar 28;11(3):2724-2733. doi: 10.1021/acsnano.6b07707. Epub 2017 Mar 9.


In situ mechanical investigation of carbon nanotube-graphene junction in three-dimensional carbon nanostructures.

Yang Y, Kim ND, Varshney V, Sihn S, Li Y, Roy AK, Tour JM, Lou J.

Nanoscale. 2017 Feb 23;9(8):2916-2924. doi: 10.1039/c6nr09897e.


Identification of TG100-115 as a new and potent TRPM7 kinase inhibitor, which suppresses breast cancer cell migration and invasion.

Song C, Bae Y, Jun J, Lee H, Kim ND, Lee KB, Hur W, Park JY, Sim T.

Biochim Biophys Acta Gen Subj. 2017 Apr;1861(4):947-957. doi: 10.1016/j.bbagen.2017.01.034. Epub 2017 Feb 1.


Identification of acetylshikonin as the novel CYP2J2 inhibitor with anti-cancer activity in HepG2 cells.

Park SH, Phuc NM, Lee J, Wu Z, Kim J, Kim H, Kim ND, Lee T, Song KS, Liu KH.

Phytomedicine. 2017 Jan 15;24:134-140. doi: 10.1016/j.phymed.2016.12.001. Epub 2016 Dec 2.


Identification of the First Selective Activin Receptor-Like Kinase 1 Inhibitor, a Reversible Version of L-783277.

Cho H, Sengupta S, Jeon SS, Hur W, Choi HG, Seo HS, Lee BJ, Kim JH, Chung M, Jeon NL, Kim ND, Sim T.

J Med Chem. 2017 Feb 23;60(4):1495-1508. doi: 10.1021/acs.jmedchem.6b01679. Epub 2017 Feb 6.


OCLI-023, a Novel Pyrimidine Compound, Suppresses Osteoclastogenesis In Vitro and Alveolar Bone Resorption In Vivo.

Ihn HJ, Lee T, Kim JA, Lee D, Kim ND, Shin HI, Bae YC, Park EK.

PLoS One. 2017 Jan 13;12(1):e0170159. doi: 10.1371/journal.pone.0170159. eCollection 2017.


MicroRNA Expression Shows Inflammatory Dysregulation and Tumor-Like Proliferative Responses in Joints of Patients With Postinfectious Lyme Arthritis.

Lochhead RB, Strle K, Kim ND, Kohler MJ, Arvikar SL, Aversa JM, Steere AC.

Arthritis Rheumatol. 2017 May;69(5):1100-1110. doi: 10.1002/art.40039.


Role of Apigenin in Cancer Prevention via the Induction of Apoptosis and Autophagy.

Sung B, Chung HY, Kim ND.

J Cancer Prev. 2016 Dec;21(4):216-226. doi: 10.15430/JCP.2016.21.4.216. Epub 2016 Dec 30. Review.


Effect of Loquat Leaf Extract on Muscle Strength, Muscle Mass, and Muscle Function in Healthy Adults: A Randomized, Double-Blinded, and Placebo-Controlled Trial.

Cho YH, Lee SY, Kim CM, Kim ND, Choe S, Lee CH, Shin JH.

Evid Based Complement Alternat Med. 2016;2016:4301621. doi: 10.1155/2016/4301621. Epub 2016 Nov 24.


Targeting ASC in NLRP3 inflammasome by caffeic acid phenethyl ester: a novel strategy to treat acute gout.

Lee HE, Yang G, Kim ND, Jeong S, Jung Y, Choi JY, Park HH, Lee JY.

Sci Rep. 2016 Dec 9;6:38622. doi: 10.1038/srep38622.


An expanded population of pathogenic regulatory T cells in giant cell arteritis is abrogated by IL-6 blockade therapy.

Miyabe C, Miyabe Y, Strle K, Kim ND, Stone JH, Luster AD, Unizony S.

Ann Rheum Dis. 2017 May;76(5):898-905. doi: 10.1136/annrheumdis-2016-210070. Epub 2016 Dec 7.


Resveratrol analogue, HS-1793, induces apoptotic cell death and cell cycle arrest through downregulation of AKT in human colon cancer cells.

Kim DH, Kim MJ, Sung B, Suh H, Jung JH, Chung HY, Kim ND.

Oncol Rep. 2017 Jan;37(1):281-288. doi: 10.3892/or.2016.5219. Epub 2016 Nov 7.


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