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Items: 1 to 50 of 92


T-cell prolymphocytic leukaemia in a patient with chronic myeloid leukaemia receiving nilotinib: first documented report.

Hanley B, Nesr G, Yebra-Fernandez E, Brown L, Rabitsch A, Killeen N, Claudiani S, Milojkovic D, Kanfer E, Apperley J, Naresh KN.

J Clin Pathol. 2019 Jul;72(7):511-512. doi: 10.1136/jclinpath-2019-205799. Epub 2019 Apr 19. No abstract available.


The Generation and Use of Allergen-Specific TCR Transgenic Animals.

Vanheerswynghels M, Toussaint W, Schuijs M, Vanhoutte L, Killeen N, Hammad H, Lambrecht BN.

Methods Mol Biol. 2018;1799:183-210. doi: 10.1007/978-1-4939-7896-0_15.


The molecular characterization of Beta globin gene in thalassemia patients reveals rare and a novel mutations in Pakistani population.

Yasmeen H, Toma S, Killeen N, Hasnain S, Foroni L.

Eur J Med Genet. 2016 Aug;59(8):355-62. doi: 10.1016/j.ejmg.2016.05.016. Epub 2016 Jun 1.


The multi-modal Australian ScienceS Imaging and Visualization Environment (MASSIVE) high performance computing infrastructure: applications in neuroscience and neuroinformatics research.

Goscinski WJ, McIntosh P, Felzmann U, Maksimenko A, Hall CJ, Gureyev T, Thompson D, Janke A, Galloway G, Killeen NE, Raniga P, Kaluza O, Ng A, Poudel G, Barnes DG, Nguyen T, Bonnington P, Egan GF.

Front Neuroinform. 2014 Mar 27;8:30. doi: 10.3389/fninf.2014.00030. eCollection 2014.


Conventional and monocyte-derived CD11b(+) dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen.

Plantinga M, Guilliams M, Vanheerswynghels M, Deswarte K, Branco-Madeira F, Toussaint W, Vanhoutte L, Neyt K, Killeen N, Malissen B, Hammad H, Lambrecht BN.

Immunity. 2013 Feb 21;38(2):322-35. doi: 10.1016/j.immuni.2012.10.016. Epub 2013 Jan 24.


Targeting macrophages in the tumour environment to enhance the efficacy of αOX40 therapy.

Gough MJ, Killeen N, Weinberg AD.

Immunology. 2012 Aug;136(4):437-47. doi: 10.1111/j.1365-2567.2012.03600.x.


Modulation of the murine CD8 gene complex following the targeted integration of human CD2-locus control region sequences.

Menzel U, Kosteas T, Tolaini M, Killeen N, Roderick K, Kioussis D.

J Immunol. 2011 Oct 1;187(7):3712-20. doi: 10.4049/jimmunol.1100709. Epub 2011 Aug 31.


A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity.

Au-Yeung BB, Levin SE, Zhang C, Hsu LY, Cheng DA, Killeen N, Shokat KM, Weiss A.

Nat Immunol. 2010 Dec;11(12):1085-92. doi: 10.1038/ni.1955. Epub 2010 Oct 31.


Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction.

Rolf J, Bell SE, Kovesdi D, Janas ML, Soond DR, Webb LM, Santinelli S, Saunders T, Hebeis B, Killeen N, Okkenhaug K, Turner M.

J Immunol. 2010 Oct 1;185(7):4042-52. doi: 10.4049/jimmunol.1001730. Epub 2010 Sep 8.


Mammalian target of rapamycin protein complex 2 regulates differentiation of Th1 and Th2 cell subsets via distinct signaling pathways.

Lee K, Gudapati P, Dragovic S, Spencer C, Joyce S, Killeen N, Magnuson MA, Boothby M.

Immunity. 2010 Jun 25;32(6):743-53. doi: 10.1016/j.immuni.2010.06.002.


Reporter alleles that inform on differences in Cre recombinase expression.

Klinger M, Chmura SA, Killeen N.

J Immunol. 2010 Jun 1;184(11):6170-6. doi: 10.4049/jimmunol.1000089. Epub 2010 Apr 28.


Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies.

Wong JC, Zhang Y, Lieuw KH, Tran MT, Forgo E, Weinfurtner K, Alzamora P, Kogan SC, Akagi K, Wolff L, Le Beau MM, Killeen N, Shannon K.

Blood. 2010 Jun 3;115(22):4524-32. doi: 10.1182/blood-2009-07-232504. Epub 2010 Mar 16.


Generalized immune activation as a direct result of activated CD4+ T cell killing.

Marques R, Williams A, Eksmond U, Wullaert A, Killeen N, Pasparakis M, Kioussis D, Kassiotis G.

J Biol. 2009;8(10):93. doi: 10.1186/jbiol194.


Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking.

Kim JK, Klinger M, Benjamin J, Xiao Y, Erle DJ, Littman DR, Killeen N.

PLoS One. 2009 Aug 11;4(8):e6580. doi: 10.1371/journal.pone.0006580.


An Integrated Object Model and Method Framework for Subject-Centric e-Research Applications.

Lohrey JM, Killeen NE, Egan GF.

Front Neuroinform. 2009 Jul 8;3:19. doi: 10.3389/neuro.11.019.2009. eCollection 2009.


The protein disulfide isomerase AGR2 is essential for production of intestinal mucus.

Park SW, Zhen G, Verhaeghe C, Nakagami Y, Nguyenvu LT, Barczak AJ, Killeen N, Erle DJ.

Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):6950-5. doi: 10.1073/pnas.0808722106. Epub 2009 Apr 9.


Thymic OX40 expression discriminates cells undergoing strong responses to selection ligands.

Klinger M, Kim JK, Chmura SA, Barczak A, Erle DJ, Killeen N.

J Immunol. 2009 Apr 15;182(8):4581-9. doi: 10.4049/jimmunol.0900010.


MLL5 contributes to hematopoietic stem cell fitness and homeostasis.

Zhang Y, Wong J, Klinger M, Tran MT, Shannon KM, Killeen N.

Blood. 2009 Feb 12;113(7):1455-63. doi: 10.1182/blood-2008-05-159905. Epub 2008 Sep 25.


CCR7 expression in developing thymocytes is linked to the CD4 versus CD8 lineage decision.

Yin X, Ladi E, Chan SW, Li O, Killeen N, Kappes DJ, Robey EA.

J Immunol. 2007 Dec 1;179(11):7358-64.


Direct alpha-oxytosylation of carbonyl compounds: one-pot synthesis of heterocycles.

John OR, Killeen NM, Knowles DA, Yau SC, Bagley MC, Tomkinson NC.

Org Lett. 2007 Sep 27;9(20):4009-12. Epub 2007 Sep 8.


OX40 costimulation turns off Foxp3+ Tregs.

Vu MD, Xiao X, Gao W, Degauque N, Chen M, Kroemer A, Killeen N, Ishii N, Li XC.

Blood. 2007 Oct 1;110(7):2501-10. Epub 2007 Jun 15.


Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

Chang JT, Palanivel VR, Kinjyo I, Schambach F, Intlekofer AM, Banerjee A, Longworth SA, Vinup KE, Mrass P, Oliaro J, Killeen N, Orange JS, Russell SM, Weninger W, Reiner SL.

Science. 2007 Mar 23;315(5819):1687-91. Epub 2007 Mar 1.


Neutrophil histamine contributes to inflammation in mycoplasma pneumonia.

Xu X, Zhang D, Zhang H, Wolters PJ, Killeen NP, Sullivan BM, Locksley RM, Lowell CA, Caughey GH.

J Exp Med. 2006 Dec 25;203(13):2907-17. Epub 2006 Dec 11.


Activation of an oncogenic microRNA cistron by provirus integration.

Wang CL, Wang BB, Bartha G, Li L, Channa N, Klinger M, Killeen N, Wabl M.

Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18680-4. Epub 2006 Nov 22.


A general method for the alpha-acyloxylation of carbonyl compounds.

Beshara CS, Hall A, Jenkins RL, Jones KL, Jones TC, Killeen NM, Taylor PH, Thomas SP, Tomkinson NC.

Org Lett. 2005 Dec 8;7(25):5729-32.


Immune complex-dependent remodeling of the airway vasculature in response to a chronic bacterial infection.

Aurora AB, Baluk P, Zhang D, Sidhu SS, Dolganov GM, Basbaum C, McDonald DM, Killeen N.

J Immunol. 2005 Nov 15;175(10):6319-26.


A two-step process for cytokine production revealed by IL-4 dual-reporter mice.

Mohrs K, Wakil AE, Killeen N, Locksley RM, Mohrs M.

Immunity. 2005 Oct;23(4):419-29.


Mast cells protect mice from Mycoplasma pneumonia.

Xu X, Zhang D, Lyubynska N, Wolters PJ, Killeen NP, Baluk P, McDonald DM, Hawgood S, Caughey GH.

Am J Respir Crit Care Med. 2006 Jan 15;173(2):219-25. Epub 2005 Oct 6.


New haplotype for the Glu104Asp mutation in triose-phosphate isomerase deficiency and prenatal diagnosis in a Spanish family.

Repiso A, Corrons JL, Vulliamy T, Killeen N, Layton M, Carreras J, Climent F.

J Inherit Metab Dis. 2005;28(5):807-9.


Selective expression of the Cre recombinase in late-stage thymocytes using the distal promoter of the Lck gene.

Zhang DJ, Wang Q, Wei J, Baimukanova G, Buchholz F, Stewart AF, Mao X, Killeen N.

J Immunol. 2005 Jun 1;174(11):6725-31.


Triggering of OX40 (CD134) on CD4(+)CD25+ T cells blocks their inhibitory activity: a novel regulatory role for OX40 and its comparison with GITR.

Valzasina B, Guiducci C, Dislich H, Killeen N, Weinberg AD, Colombo MP.

Blood. 2005 Apr 1;105(7):2845-51. Epub 2004 Dec 9.


Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.

Zhu J, Min B, Hu-Li J, Watson CJ, Grinberg A, Wang Q, Killeen N, Urban JF Jr, Guo L, Paul WE.

Nat Immunol. 2004 Nov;5(11):1157-65. Epub 2004 Oct 10.


CCR7 directs the migration of thymocytes into the thymic medulla.

Kwan J, Killeen N.

J Immunol. 2004 Apr 1;172(7):3999-4007.


Distinct roles for the OX40-OX40 ligand interaction in regulatory and nonregulatory T cells.

Takeda I, Ine S, Killeen N, Ndhlovu LC, Murata K, Satomi S, Sugamura K, Ishii N.

J Immunol. 2004 Mar 15;172(6):3580-9.


A mouse genetic model for familial cholestasis caused by ATP8B1 mutations reveals perturbed bile salt homeostasis but no impairment in bile secretion.

Pawlikowska L, Groen A, Eppens EF, Kunne C, Ottenhoff R, Looije N, Knisely AS, Killeen NP, Bull LN, Elferink RP, Freimer NB.

Hum Mol Genet. 2004 Apr 15;13(8):881-92. Epub 2004 Feb 19.


CD134 plays a crucial role in the pathogenesis of EAE and is upregulated in the CNS of patients with multiple sclerosis.

Carboni S, Aboul-Enein F, Waltzinger C, Killeen N, Lassmann H, Peña-Rossi C.

J Neuroimmunol. 2003 Dec;145(1-2):1-11.


Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients.

Blazar BR, Sharpe AH, Chen AI, Panoskaltsis-Mortari A, Lees C, Akiba H, Yagita H, Killeen N, Taylor PA.

Blood. 2003 May 1;101(9):3741-8. Epub 2003 Jan 9.


Generation and characterization of ecto-ADP-ribosyltransferase ART2.1/ART2.2-deficient mice.

Ohlrogge W, Haag F, Löhler J, Seman M, Littman DR, Killeen N, Koch-Nolte F.

Mol Cell Biol. 2002 Nov;22(21):7535-42.


A new spin on an unusual tail.

Killeen N.

Nat Immunol. 2002 May;3(5):419-21. No abstract available.


Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage.

Zou YR, Sunshine MJ, Taniuchi I, Hatam F, Killeen N, Littman DR.

Nat Genet. 2001 Nov;29(3):332-6.


CD4 promotes breadth in the TCR repertoire.

Wang Q, Malherbe L, Zhang D, Zingler K, Glaichenhaus N, Killeen N.

J Immunol. 2001 Oct 15;167(8):4311-20.


OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells.

Rogers PR, Song J, Gramaglia I, Killeen N, Croft M.

Immunity. 2001 Sep;15(3):445-55.


Modeling myeloid leukemia tumor suppressor gene inactivation in the mouse.

Shannon KM, Le Beau MM, Largaespada DA, Killeen N.

Semin Cancer Biol. 2001 Jun;11(3):191-200. Review.


The TNF and TNF receptor superfamilies: integrating mammalian biology.

Locksley RM, Killeen N, Lenardo MJ.

Cell. 2001 Feb 23;104(4):487-501. Review. No abstract available.


Impaired survival of T helper cells in the absence of CD4.

Strong J, Wang Q, Killeen N.

Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2566-71. Epub 2001 Feb 20.


An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity.

Majeti R, Xu Z, Parslow TG, Olson JL, Daikh DI, Killeen N, Weiss A.

Cell. 2000 Dec 22;103(7):1059-70.


Determination of the tyrosine phosphorylation sites in the T cell transmembrane glycoprotein CD5.

Dennehy KM, Ferris WF, Veenstra H, Zuckerman LA, Killeen N, Beyers AD.

Int Immunol. 2001 Feb;13(2):149-56.


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