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Items: 1 to 50 of 64

1.

Identification of genetic variants predictive of early onset pancreatic cancer through a population science analysis of functional genomic datasets.

Chen J, Wu X, Huang Y, Chen W, Brand RE, Killary AM, Sen S, Frazier ML.

Oncotarget. 2016 Aug 30;7(35):56480-56490. doi: 10.18632/oncotarget.10924.

2.

Definitive Characterization of CA 19-9 in Resectable Pancreatic Cancer Using a Reference Set of Serum and Plasma Specimens.

Haab BB, Huang Y, Balasenthil S, Partyka K, Tang H, Anderson M, Allen P, Sasson A, Zeh H, Kaul K, Kletter D, Ge S, Bern M, Kwon R, Blasutig I, Srivastava S, Frazier ML, Sen S, Hollingsworth MA, Rinaudo JA, Killary AM, Brand RE.

PLoS One. 2015 Oct 2;10(10):e0139049. doi: 10.1371/journal.pone.0139049. eCollection 2015.

3.

Next generation sequencing of pancreatic cyst fluid microRNAs from low grade-benign and high grade-invasive lesions.

Wang J, Paris PL, Chen J, Ngo V, Yao H, Frazier ML, Killary AM, Liu CG, Liang H, Mathy C, Bondada S, Kirkwood K, Sen S.

Cancer Lett. 2015 Jan 28;356(2 Pt B):404-9. doi: 10.1016/j.canlet.2014.09.029. Epub 2014 Oct 7.

4.

DEAR1, a novel tumor suppressor that regulates cell polarity and epithelial plasticity.

Chen N, Balasenthil S, Reuther J, Killary AM.

Cancer Res. 2014 Oct 15;74(20):5683-9. doi: 10.1158/0008-5472.CAN-14-1171. Epub 2014 Sep 26. Review.

5.

Circulating microRNAs in Pancreatic Juice as Candidate Biomarkers of Pancreatic Cancer.

Wang J, Raimondo M, Guha S, Chen J, Diao L, Dong X, Wallace MB, Killary AM, Frazier ML, Woodward TA, Wang J, Sen S.

J Cancer. 2014 Sep 16;5(8):696-705. doi: 10.7150/jca.10094. eCollection 2014.

6.

Loss of the novel tumour suppressor and polarity gene Trim62 (Dear1) synergizes with oncogenic Ras in invasive lung cancer.

Quintás-Cardama A, Post SM, Solis LM, Xiong S, Yang P, Chen N, Wistuba II, Killary AM, Lozano G.

J Pathol. 2014 Sep;234(1):108-19. doi: 10.1002/path.4385. Epub 2014 Jul 16.

7.

DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-β-driven epithelial-mesenchymal transition.

Chen N, Balasenthil S, Reuther J, Frayna A, Wang Y, Chandler DS, Abruzzo LV, Rashid A, Rodriguez J, Lozano G, Cao Y, Lokken E, Chen J, Frazier ML, Sahin AA, Wistuba II, Sen S, Lott ST, Killary AM.

Cancer Discov. 2013 Oct;3(10):1172-89. doi: 10.1158/2159-8290.CD-12-0499. Epub 2013 Jul 9.

8.

Putative tumor suppressor gene SEL1L was downregulated by aberrantly upregulated hsa-mir-155 in human pancreatic ductal adenocarcinoma.

Liu Q, Chen J, Wang J, Amos C, Killary AM, Sen S, Wei C, Frazier ML.

Mol Carcinog. 2014 Sep;53(9):711-21. doi: 10.1002/mc.22023. Epub 2013 May 9.

9.

VGLL3 expression is associated with a tumor suppressor phenotype in epithelial ovarian cancer.

Gambaro K, Quinn MC, Wojnarowicz PM, Arcand SL, de Ladurantaye M, Barrès V, Ripeau JS, Killary AM, Davis EC, Lavoie J, Provencher DM, Mes-Masson AM, Chevrette M, Tonin PN.

Mol Oncol. 2013 Jun;7(3):513-30. doi: 10.1016/j.molonc.2012.12.006. Epub 2013 Jan 16.

10.

Susceptibility locus for lung cancer at 15q25.1 is not associated with risk of pancreatic cancer.

Chen J, Wu X, Pande M, Amos CI, Killary AM, Sen S, Frazier ML.

Pancreas. 2011 Aug;40(6):872-5. doi: 10.1097/MPA.0b013e318219dafe.

11.

A single-nucleotide polymorphism in tumor suppressor gene SEL1L as a predictive and prognostic marker for pancreatic ductal adenocarcinoma in Caucasians.

Liu Q, Chen J, Mai B, Amos C, Killary AM, Sen S, Wei C, Frazier ML.

Mol Carcinog. 2012 May;51(5):433-8. doi: 10.1002/mc.20808. Epub 2011 Jun 7.

12.

A migration signature and plasma biomarker panel for pancreatic adenocarcinoma.

Balasenthil S, Chen N, Lott ST, Chen J, Carter J, Grizzle WE, Frazier ML, Sen S, Killary AM.

Cancer Prev Res (Phila). 2011 Jan;4(1):137-49. doi: 10.1158/1940-6207.CAPR-10-0025. Epub 2010 Nov 11.

13.

Genetic variations of the PI3K-AKT-mTOR pathway and clinical outcome in muscle invasive and metastatic bladder cancer patients.

Chen M, Gu J, Delclos GL, Killary AM, Fan Z, Hildebrandt MA, Chamberlain RM, Grossman HB, Dinney CP, Wu X.

Carcinogenesis. 2010 Aug;31(8):1387-91. doi: 10.1093/carcin/bgq110. Epub 2010 Jun 7.

14.

Genetic variants of p21 and p27 and pancreatic cancer risk in non-Hispanic Whites: a case-control study.

Chen J, Amos CI, Merriman KW, Wei Q, Sen S, Killary AM, Frazier ML.

Pancreas. 2010 Jan;39(1):1-4. doi: 10.1097/MPA.0b013e3181bd51c8.

15.

MicroRNAs in plasma of pancreatic ductal adenocarcinoma patients as novel blood-based biomarkers of disease.

Wang J, Chen J, Chang P, LeBlanc A, Li D, Abbruzzesse JL, Frazier ML, Killary AM, Sen S.

Cancer Prev Res (Phila). 2009 Sep;2(9):807-13. doi: 10.1158/1940-6207.CAPR-09-0094. Epub 2009 Sep 1.

16.

DEAR1 is a dominant regulator of acinar morphogenesis and an independent predictor of local recurrence-free survival in early-onset breast cancer.

Lott ST, Chen N, Chandler DS, Yang Q, Wang L, Rodriguez M, Xie H, Balasenthil S, Buchholz TA, Sahin AA, Chaung K, Zhang B, Olufemi SE, Chen J, Adams H, Band V, El-Naggar AK, Frazier ML, Keyomarsi K, Hunt KK, Sen S, Haffty B, Hewitt SM, Krahe R, Killary AM.

PLoS Med. 2009 May 26;6(5):e1000068. doi: 10.1371/journal.pmed.1000068. Epub 2009 May 5.

17.

Polymorphisms of p16, p27, p73, and MDM2 modulate response and survival of pancreatic cancer patients treated with preoperative chemoradiation.

Chen J, Li D, Killary AM, Sen S, Amos CI, Evans DB, Abbruzzese JL, Frazier ML.

Ann Surg Oncol. 2009 Feb;16(2):431-9. doi: 10.1245/s10434-008-0220-8. Epub 2008 Nov 20.

PMID:
19020940
18.

Polymorphisms of p21 and p27 jointly contribute to an earlier age at diagnosis of pancreatic cancer.

Chen J, Killary AM, Sen S, Amos CI, Evans DB, Abbruzzese JL, Frazier ML.

Cancer Lett. 2008 Dec 8;272(1):32-9. doi: 10.1016/j.canlet.2008.06.022. Epub 2008 Aug 9.

19.

Targeted disruption of Aurora A causes abnormal mitotic spindle assembly, chromosome misalignment and embryonic lethality.

Sasai K, Parant JM, Brandt ME, Carter J, Adams HP, Stass SA, Killary AM, Katayama H, Sen S.

Oncogene. 2008 Jul 3;27(29):4122-7. doi: 10.1038/onc.2008.47. Epub 2008 Mar 17.

PMID:
18345035
20.

Fine mapping of the NRC-1 tumor suppressor locus within chromosome 3p12.

Zhang K, Lott ST, Jin L, Killary AM.

Biochem Biophys Res Commun. 2007 Aug 31;360(3):531-8. Epub 2007 Jun 19.

PMID:
17624313
21.

Aurora-A and p16 polymorphisms contribute to an earlier age at diagnosis of pancreatic cancer in Caucasians.

Chen J, Li D, Wei C, Sen S, Killary AM, Amos CI, Evans DB, Abbruzzese JL, Frazier ML.

Clin Cancer Res. 2007 May 15;13(10):3100-4.

22.

High frequency loss of heterozygosity in von Hippel-Lindau (VHL)-associated and sporadic pancreatic islet cell tumors: evidence for a stepwise mechanism for malignant conversion in VHL tumorigenesis.

Lott ST, Chandler DS, Curley SA, Foster CJ, El-Naggar A, Frazier M, Strong LC, Lovell M, Killary AM.

Cancer Res. 2002 Apr 1;62(7):1952-5.

23.

Functional evidence for an ovarian cancer tumor suppressor gene on chromosome 22 by microcell-mediated chromosome transfer.

Kruzelock RP, Cuevas BD, Wiener JR, Xu FJ, Yu Y, Cabeza-Arvelaiz Y, Pershouse M, Lovell MM, Killary AM, Mills GB, Bast RC Jr.

Oncogene. 2000 Dec 14;19(54):6277-85.

24.

Chromosome 18 suppresses the tumorigenicity of prostate cancer cells.

Padalecki SS, Johnson-Pais TL, Killary AM, Leach RJ.

Genes Chromosomes Cancer. 2001 Mar;30(3):221-9.

PMID:
11170278
25.

Cytogenetic analysis of a primary salivary gland myoepithelioma.

el-Naggar AK, Lovell M, Callender DL, Ordonez NG, Killary AM.

Cancer Genet Cytogenet. 1999 Aug;113(1):49-53.

PMID:
10459346
26.
27.

Limited nonrandom chromosomal aberrations in a recurrent adenoid cystic carcinoma of the parotid gland.

el-Naggar AK, Lovell M, Callender DL, Killary AM.

Cancer Genet Cytogenet. 1999 Feb;109(1):66-9.

PMID:
9973962
28.

Concurrent cytogenetic, interphase fluorescence in situ hybridization and DNA flow cytometric analyses of a carcinoma ex-pleomorphic adenoma of parotid gland.

el-Naggar AK, Lovell M, Callender DL, Ordonez NG, Killary AM.

Cancer Genet Cytogenet. 1998 Dec;107(2):132-6. Review.

PMID:
9844608
29.

Physical and functional mapping of a tumor suppressor locus for renal cell carcinoma within chromosome 3p12.

Lott ST, Lovell M, Naylor SL, Killary AM.

Cancer Res. 1998 Aug 15;58(16):3533-7.

30.
31.

Multiple unrelated translocations in a metastatic epimyoepithelial carcinoma of the parotid gland.

el-Naggar AK, Lovell M, Ordonez NG, Killary AM.

Cancer Genet Cytogenet. 1998 Jan 15;100(2):155-8.

PMID:
9428361
32.

Suppression of transformed phenotype and tumorigenicity after transfer of chromosome 4 into U251 human glioma cells.

Pershouse MA, Ligon AH, Pereira-Smith OM, Killary AM, Yung WK, Steck PA.

Genes Chromosomes Cancer. 1997 Nov;20(3):260-7.

PMID:
9365833
33.

An 80 Kb P1 clone from chromosome 3p21.3 suppresses tumor growth in vivo.

Todd MC, Xiang RH, Garcia DK, Kerbacher KE, Moore SL, Hensel CH, Liu P, Siciliano MJ, Kok K, van den Berg A, Veldhuis P, Buys CH, Killary AM, Naylor SL.

Oncogene. 1996 Dec 5;13(11):2387-96.

PMID:
8957080
34.
35.

Tumor suppression and apoptosis of human prostate carcinoma mediated by a genetic locus within human chromosome 10pter-q11.

Sanchez Y, Lovell M, Marin MC, Wong PE, Wolf-Ledbetter ME, McDonnell TJ, Killary AM.

Proc Natl Acad Sci U S A. 1996 Mar 19;93(6):2551-6.

36.

A mucoepidermoid carcinoma of minor salivary gland with t(11;19)(q21;p13.1) as the only karyotypic abnormality.

El-Naggar AK, Lovell M, Killary AM, Clayman GL, Batsakis JG.

Cancer Genet Cytogenet. 1996 Mar;87(1):29-33. Review.

PMID:
8646736
37.

Production of Microcell Hybrids

Killary AM, Lott ST.

Methods. 1996 Feb;9(1):3-11.

PMID:
9245337
38.

Metastasis suppressor genes for prostate cancer.

Ichikawa T, Nihei N, Kuramochi H, Kawana Y, Killary AM, Rinker-SchaefferCW, Barrett JC, Isaacs JT, Kugoh H, Oshimura M, Shimazaki J.

Prostate Suppl. 1996;6:31-5.

PMID:
8630227
39.

Localization of metastasis suppressor gene(s) for rat prostatic cancer to the long arm of human chromosome 10.

Nihei N, Ichikawa T, Kawana Y, Kuramochi H, Kugo H, Oshimura M, Killary AM, Rinker-Schaeffer CW, Barrett JC, Isaacs JT, et al.

Genes Chromosomes Cancer. 1995 Oct;14(2):112-9.

PMID:
8527392
40.

Gene expression in response to retinoic acid in novel human chromosome 21 monochromosomal cell hybrids.

Yulug IG, Killary AM, Sandhu AK, Athwal RS, Fox M, Fisher EM.

Somat Cell Mol Genet. 1995 Sep;21(5):357-65.

PMID:
8619133
41.

MSX1 inhibits myoD expression in fibroblast x 10T1/2 cell hybrids.

Woloshin P, Song K, Degnin C, Killary AM, Goldhamer DJ, Sassoon D, Thayer MJ.

Cell. 1995 Aug 25;82(4):611-20.

42.

Microcell fusion.

Killary AM, Fournier RE.

Methods Enzymol. 1995;254:133-52. No abstract available.

PMID:
8531682
43.

A tumor suppressor locus within 3p14-p12 mediates rapid cell death of renal cell carcinoma in vivo.

Sanchez Y, el-Naggar A, Pathak S, Killary AM.

Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):3383-7.

44.

Analysis of the functional role of chromosome 10 loss in human glioblastomas.

Pershouse MA, Stubblefield E, Hadi A, Killary AM, Yung WK, Steck PA.

Cancer Res. 1993 Oct 15;53(20):5043-50.

45.

A homozygous deletion on chromosome 3 in a small cell lung cancer cell line correlates with a region of tumor suppressor activity.

Daly MC, Xiang RH, Buchhagen D, Hensel CH, Garcia DK, Killary AM, Minna JD, Naylor SL.

Oncogene. 1993 Jul;8(7):1721-9.

PMID:
8390035
46.

Definition of a tumor suppressor locus within human chromosome 3p21-p22.

Killary AM, Wolf ME, Giambernardi TA, Naylor SL.

Proc Natl Acad Sci U S A. 1992 Nov 15;89(22):10877-81.

47.

Construction of a human chromosome 4 YAC pool and analysis of artificial chromosome stability.

Sleister HM, Mills KA, Blackwell SE, Killary AM, Murray JC, Malone RE.

Nucleic Acids Res. 1992 Jul 11;20(13):3419-25.

48.

Dissociation of cytotoxicity and DNA cleavage activity induced by topoisomerase II-reactive intercalating agents in hamster-human somatic cell hybrids.

Glisson BS, Killary AM, Merta P, Ross WE, Siciliano J, Siciliano MJ.

Cancer Chemother Pharmacol. 1992;31(2):131-8.

PMID:
1333369
49.

Genetic analysis of indefinite division in human cells: evidence for a cell senescence-related gene(s) on human chromosome 4.

Ning Y, Weber JL, Killary AM, Ledbetter DH, Smith JR, Pereira-Smith OM.

Proc Natl Acad Sci U S A. 1991 Jul 1;88(13):5635-9.

50.

Chromosomal localization of the human annexin III (ANX3) gene.

Tait JF, Frankenberry DA, Miao CH, Killary AM, Adler DA, Disteche CM.

Genomics. 1991 Jun;10(2):441-8.

PMID:
1830024

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