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Items: 1 to 50 of 54

1.

Facts and conjectures on calmodulin and its cousin proteins, parvalbumin and troponin C.

Haiech J, Moreau M, Leclerc C, Kilhoffer MC.

Biochim Biophys Acta Mol Cell Res. 2019 Jul;1866(7):1046-1053. doi: 10.1016/j.bbamcr.2019.01.014. Epub 2019 Feb 1. Review.

PMID:
30716407
2.

Using Data Mining to Explore Calmodulin Bibliography.

Haiech J, Kilhoffer MC.

Methods Mol Biol. 2019;1929:3-14. doi: 10.1007/978-1-4939-9030-6_1.

PMID:
30710263
3.

Ca2+-Dependent Transcriptional Repressors KCNIP and Regulation of Prognosis Genes in Glioblastoma.

Néant I, Haiech J, Kilhoffer MC, Aulestia FJ, Moreau M, Leclerc C.

Front Mol Neurosci. 2018 Dec 18;11:472. doi: 10.3389/fnmol.2018.00472. eCollection 2018. Review.

4.

Quiescence status of glioblastoma stem-like cells involves remodelling of Ca2+ signalling and mitochondrial shape.

Aulestia FJ, Néant I, Dong J, Haiech J, Kilhoffer MC, Moreau M, Leclerc C.

Sci Rep. 2018 Jun 27;8(1):9731. doi: 10.1038/s41598-018-28157-8.

5.

WNK1 kinase and its partners Akt, SGK1 and NBC-family Na+/HCO3- cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling.

Chen W, Zebaze LN, Dong J, Chézeau L, Inquimbert P, Hugel S, Niu S, Bihel F, Boutant E, Réal E, Villa P, Junier MP, Chneiweiss H, Hibert M, Haiech J, Kilhoffer MC, Zeniou M.

Oncotarget. 2018 Jun 5;9(43):27197-27219. doi: 10.18632/oncotarget.25509. eCollection 2018 Jun 5.

6.

Lebbeckoside C, a new triterpenoid saponin from the stem barks of Albizia lebbeck inhibits the growth of human glioblastoma cells.

Noté OP, Ngo Mbing J, Kilhoffer MC, Pegnyemb DE, Lobstein A.

Nat Prod Res. 2019 Aug;33(16):2292-2299. doi: 10.1080/14786419.2018.1440231. Epub 2018 Feb 19.

PMID:
29457747
7.

Bisacodyl and its cytotoxic activity on human glioblastoma stem-like cells. Implication of inositol 1,4,5-triphosphate receptor dependent calcium signaling.

Dong J, Aulestia FJ, Assad Kahn S, Zeniou M, Dubois LG, El-Habr EA, Daubeuf F, Tounsi N, Cheshier SH, Frossard N, Junier MP, Chneiweiss H, Néant I, Moreau M, Leclerc C, Haiech J, Kilhoffer MC.

Biochim Biophys Acta Mol Cell Res. 2017 Jun;1864(6):1018-1027. doi: 10.1016/j.bbamcr.2017.01.010. Epub 2017 Jan 18.

8.

Cancer Stem Cell Quiescence and Plasticity as Major Challenges in Cancer Therapy.

Chen W, Dong J, Haiech J, Kilhoffer MC, Zeniou M.

Stem Cells Int. 2016;2016:1740936. doi: 10.1155/2016/1740936. Epub 2016 Jun 21. Review.

9.

The anti-hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ-dependent inhibition of the AKT pathway.

Assad Kahn S, Costa SL, Gholamin S, Nitta RT, Dubois LG, Fève M, Zeniou M, Coelho PL, El-Habr E, Cadusseau J, Varlet P, Mitra SS, Devaux B, Kilhoffer MC, Cheshier SH, Moura-Neto V, Haiech J, Junier MP, Chneiweiss H.

EMBO Mol Med. 2016 May 2;8(5):511-26. doi: 10.15252/emmm.201505421. Print 2016 May.

10.

Calcium signaling orchestrates glioblastoma development: Facts and conjunctures.

Leclerc C, Haeich J, Aulestia FJ, Kilhoffer MC, Miller AL, Néant I, Webb SE, Schaeffer E, Junier MP, Chneiweiss H, Moreau M.

Biochim Biophys Acta. 2016 Jun;1863(6 Pt B):1447-59. doi: 10.1016/j.bbamcr.2016.01.018. Epub 2016 Jan 28. Review.

11.

Glioblastoma and calcium signaling--analysis of calcium toolbox expression.

Robil N, Petel F, Kilhoffer MC, Haiech J.

Int J Dev Biol. 2015;59(7-9):407-15. doi: 10.1387/ijdb.150200jh.

12.

Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells.

Zeniou M, Fève M, Mameri S, Dong J, Salomé C, Chen W, El-Habr EA, Bousson F, Sy M, Obszynski J, Boh A, Villa P, Assad Kahn S, Didier B, Bagnard D, Junier MP, Chneiweiss H, Haiech J, Hibert M, Kilhoffer MC.

PLoS One. 2015 Aug 13;10(8):e0134793. doi: 10.1371/journal.pone.0134793. eCollection 2015.

13.

Triterpenoid saponins from Albizia lebbeck (L.) Benth and their inhibitory effect on the survival of high grade human brain tumor cells.

Noté OP, Jihu D, Antheaume C, Zeniou M, Pegnyemb DE, Guillaume D, Chneiwess H, Kilhoffer MC, Lobstein A.

Carbohydr Res. 2015 Mar 2;404:26-33. doi: 10.1016/j.carres.2014.12.004. Epub 2015 Jan 23.

PMID:
25662738
14.

Comparative expression study of the endo-G protein coupled receptor (GPCR) repertoire in human glioblastoma cancer stem-like cells, U87-MG cells and non malignant cells of neural origin unveils new potential therapeutic targets.

Fève M, Saliou JM, Zeniou M, Lennon S, Carapito C, Dong J, Van Dorsselaer A, Junier MP, Chneiweiss H, Cianférani S, Haiech J, Kilhoffer MC.

PLoS One. 2014 Mar 24;9(3):e91519. doi: 10.1371/journal.pone.0091519. eCollection 2014.

15.

A general framework improving teaching ligand binding to a macromolecule.

Haiech J, Gendrault Y, Kilhoffer MC, Ranjeva R, Madec M, Lallement C.

Biochim Biophys Acta. 2014 Oct;1843(10):2348-55. doi: 10.1016/j.bbamcr.2014.03.013. Epub 2014 Mar 20.

16.

A general framework to characterize inhibitors of calmodulin: use of calmodulin inhibitors to study the interaction between calmodulin and its calmodulin binding domains.

Audran E, Dagher R, Gioria S, Tsvetkov PO, Kulikova AA, Didier B, Villa P, Makarov AA, Kilhoffer MC, Haiech J.

Biochim Biophys Acta. 2013 Jul;1833(7):1720-31. doi: 10.1016/j.bbamcr.2013.01.008. Epub 2013 Jan 17.

17.

New aspects of calmodulin-calmodulin binding domains recognition.

Audran E, Dagher R, Gioria S, Kilhoffer MC, Haiech J.

Methods Mol Biol. 2013;963:57-72. doi: 10.1007/978-1-62703-230-8_4.

PMID:
23296604
18.

Personalized medicine and education: the challenge.

Haiech J, Kilhoffer MC.

Croat Med J. 2012 Aug;53(4):298-300.

19.

[System biology and synthetic biology modify drug discovery and development].

Haiech J, Ranjeva R, Kilhoffer MC.

Med Sci (Paris). 2012 Feb;28(2):207-12. doi: 10.1051/medsci/2012282020. Epub 2012 Feb 27. Review. French.

20.

Revisiting intracellular calcium signaling semantics.

Haiech J, Audran E, Fève M, Ranjeva R, Kilhoffer MC.

Biochimie. 2011 Dec;93(12):2029-37. doi: 10.1016/j.biochi.2011.05.003. Epub 2011 May 19. Review.

PMID:
21620928
21.

Homodimerization of the death-associated protein kinase catalytic domain: development of a new small molecule fluorescent reporter.

Zimmermann M, Atmanene C, Xu Q, Fouillen L, Van Dorsselaer A, Bonnet D, Marsol C, Hibert M, Sanglier-Cianferani S, Pigault C, McNamara LK, Watterson DM, Haiech J, Kilhoffer MC.

PLoS One. 2010 Nov 30;5(11):e14120. doi: 10.1371/journal.pone.0014120.

22.

A general strategy to characterize calmodulin-calcium complexes involved in CaM-target recognition: DAPK and EGFR calmodulin binding domains interact with different calmodulin-calcium complexes.

Dagher R, Peng S, Gioria S, Fève M, Zeniou M, Zimmermann M, Pigault C, Haiech J, Kilhoffer MC.

Biochim Biophys Acta. 2011 May;1813(5):1059-67. doi: 10.1016/j.bbamcr.2010.11.004. Epub 2010 Nov 30.

23.

Calcium fingerprints induced by calmodulin interactors in eukaryotic cells.

Dagher R, Brière C, Fève M, Zeniou M, Pigault C, Mazars C, Chneiweiss H, Ranjeva R, Kilhoffer MC, Haiech J.

Biochim Biophys Acta. 2009 Jun;1793(6):1068-77. doi: 10.1016/j.bbamcr.2008.11.019. Epub 2008 Dec 14.

24.

[Calcium binding proteins as therapeutic targets?].

Haiech J, Pigault C, Dagher R, Villa P, Kilhoffer MC.

Med Sci (Paris). 2006 Dec;22(12):1020-2. French. No abstract available.

25.

Use of a fluorescent polarization based high throughput assay to identify new calmodulin ligands.

Dagher R, Pigault C, Bonnet D, Boeglin D, Pourbaix C, Kilhoffer MC, Villa P, Wermuth CG, Hibert M, Haiech J.

Biochim Biophys Acta. 2006 Nov;1763(11):1250-5. Epub 2006 Sep 26.

26.
27.

Unfolding of rabbit muscle creatine kinase induced by acid. A study using electrospray ionization mass spectrometry, isothermal titration calorimetry, and fluorescence spectroscopy.

Liang Y, Du F, Sanglier S, Zhou BR, Xia Y, Van Dorsselaer A, Maechling C, Kilhoffer MC, Haiech J.

J Biol Chem. 2003 Aug 8;278(32):30098-105. Epub 2003 May 27.

28.

Deconvolution of calcium-binding curves. Facts and fantasies.

Haiech J, Kilhoffer MC.

Methods Mol Biol. 2002;173:25-42. No abstract available.

PMID:
11859766
29.

The Q15H mutation enables Crh, a Bacillus subtilis HPr-like protein, to carry out some regulatory HPr functions, but does not make it an effective phosphocarrier for sugar transport.

Martin-Verstraete I, Galinier A, Darbon E, Quentin Y, Kilhoffer MC, Charrier V, Haiech J, Rapoport G, Deutscher J.

Microbiology. 1999 Nov;145 ( Pt 11):3195-204.

PMID:
10589728
30.

Calcium signalling in Bacillus subtilis.

Herbaud ML, Guiseppi A, Denizot F, Haiech J, Kilhoffer MC.

Biochim Biophys Acta. 1998 Dec 10;1448(2):212-26.

31.

Thermodynamic analysis of calcium and magnesium binding to calmodulin.

Gilli R, Lafitte D, Lopez C, Kilhoffer M, Makarov A, Briand C, Haiech J.

Biochemistry. 1998 Apr 21;37(16):5450-6.

PMID:
9548926
32.

New protein kinase and protein phosphatase families mediate signal transduction in bacterial catabolite repression.

Galinier A, Kravanja M, Engelmann R, Hengstenberg W, Kilhoffer MC, Deutscher J, Haiech J.

Proc Natl Acad Sci U S A. 1998 Feb 17;95(4):1823-8.

33.

The Bacillus subtilis crh gene encodes a HPr-like protein involved in carbon catabolite repression.

Galinier A, Haiech J, Kilhoffer MC, Jaquinod M, Stülke J, Deutscher J, Martin-Verstraete I.

Proc Natl Acad Sci U S A. 1997 Aug 5;94(16):8439-44.

34.

Microbial and genetic approaches to the study of structure-function relationships of proteins.

Barras F, Kilhoffer MC, Bortoli-German I, Haiech J.

Prog Mol Subcell Biol. 1994;13:81-99. Review. No abstract available.

PMID:
8162233
35.

The heterodimer calmodulin: myosin light-chain kinase as a prototype vertebrate calcium signal transduction complex.

Kilhoffer MC, Lukas TJ, Watterson DM, Haiech J.

Biochim Biophys Acta. 1992 Nov 10;1160(1):8-15.

PMID:
1420336
37.

Distribution of separations between groups in an engineered calmodulin.

Steiner RF, Albaugh S, Kilhoffer MC.

J Fluoresc. 1991 Mar;1(1):15-22. doi: 10.1007/BF00865254.

PMID:
24242906
38.

Restoration of the calcium binding activity of mutant calmodulins toward normal by the presence of a calmodulin binding structure.

Haiech J, Kilhoffer MC, Lukas TJ, Craig TA, Roberts DM, Watterson DM.

J Biol Chem. 1991 Feb 25;266(6):3427-31.

39.

Mutant analysis approaches to understanding calcium signal transduction through calmodulin and calmodulin regulated enzymes.

Haiech J, Kilhoffer MC, Craig TA, Lukas TJ, Wilson E, Guerra-Santos L, Watterson DM.

Adv Exp Med Biol. 1990;269:43-56. Review.

PMID:
2191562
40.

Time-resolved fluorescence study of VU-9 calmodulin, an engineered calmodulin possessing a single tryptophan residue.

Chabbert M, Kilhoffer MC, Watterson DM, Haiech J, Lami H.

Biochemistry. 1989 Jul 11;28(14):6093-8.

PMID:
2775754
41.

Fluorescence characterization of VU-9 calmodulin, an engineered calmodulin with one tryptophan in calcium binding domain III.

Kilhoffer MC, Roberts DM, Adibi A, Watterson DM, Haiech J.

Biochemistry. 1989 Jul 11;28(14):6086-92.

PMID:
2775753
42.
43.

Calmodulin and its role in intracellular calcium regulation.

Stoclet JC, Gérard D, Kilhoffer MC, Lugnier C, Miller R, Schaeffer P.

Prog Neurobiol. 1987;29(4):321-64. Review. No abstract available.

PMID:
3303136
44.

The effect of plasma gelsolin on actin filaments. Ca2+-dependency of the capping and severing activities.

Kilhoffer MC, Mely Y, Gérard D.

Biochem Biophys Res Commun. 1985 Sep 30;131(3):1132-8.

PMID:
2996537
46.

Calcium-independent activation of adenylate cyclase by calmodulin.

Kilhoffer MC, Cook GH, Wolff J.

Eur J Biochem. 1983 Jun 1;133(1):11-5.

47.

Ion binding to calmodulin. A comparison with other intracellular calcium-binding proteins.

Kilhoffer MC, Haiech J, Demaille JG.

Mol Cell Biochem. 1983;51(1):33-54. Review.

PMID:
6343834
48.

Forskolin stimulation of thyroid adenylate cyclase and cyclic 3',5'-adenosine monophosphate accumulation.

Fradkin JE, Cook GH, Kilhoffer MC, Wolff J.

Endocrinology. 1982 Sep;111(3):849-56.

PMID:
6286284
49.

Tyrosine fluorescence of ram testis and octopus calmodulins. Effects of calcium, magnesium, and ionic strength.

Kilhoffer MC, Demaille JG, Gérard D.

Biochemistry. 1981 Jul 21;20(15):4407-14. No abstract available.

PMID:
7284330
50.

Octopus calmodulin. The trimethyllysyl residue is not required for myosin light chain kinase activation.

Molla A, Kilhoffer MC, Ferraz C, Audemard E, Walsh MP, Demaille JG.

J Biol Chem. 1981 Jan 10;256(1):15-8.

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