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Items: 50

1.

Modulation of LPS-induced pulmonary neutrophil infiltration and cytokine production by the selective PPARbeta/delta ligand GW0742.

Haskova Z, Hoang B, Luo G, Morgan LA, Billin AN, Barone FC, Shearer BG, Barton ME, Kilgore KS.

Inflamm Res. 2008 Jul;57(7):314-21. doi: 10.1007/s00011-007-7157-4.

PMID:
18622687
2.

PPARbeta/delta ligands as modulators of the inflammatory response.

Kilgore KS, Billin AN.

Curr Opin Investig Drugs. 2008 May;9(5):463-9. Review.

PMID:
18465655
3.

Use of a portable thermal imaging unit as a rapid, quantitative method of evaluating inflammation and experimental arthritis.

Sanchez BM, Lesch M, Brammer D, Bove SE, Thiel M, Kilgore KS.

J Pharmacol Toxicol Methods. 2008 May-Jun;57(3):169-75. doi: 10.1016/j.vascn.2008.01.003. Epub 2008 Feb 9.

PMID:
18367413
4.

Synthesis and SAR comparison of regioisomeric aryl naphthyridines as potent mGlu5 receptor antagonists.

Galatsis P, Yamagata K, Wendt JA, Connolly CJ, Mickelson JW, Milbank JB, Bove SE, Knauer CS, Brooker RM, Augelli-Szafran CE, Schwarz RD, Kinsora JJ, Kilgore KS.

Bioorg Med Chem Lett. 2007 Dec 1;17(23):6525-8. Epub 2007 Sep 29.

PMID:
17936624
5.

Synthesis and SAR of 2-aryl pyrido[2,3-d]pyrimidines as potent mGlu5 receptor antagonists.

Wendt JA, Deeter SD, Bove SE, Knauer CS, Brooker RM, Augelli-Szafran CE, Schwarz RD, Kinsora JJ, Kilgore KS.

Bioorg Med Chem Lett. 2007 Oct 1;17(19):5396-9. Epub 2007 Aug 6.

PMID:
17723296
6.

Surgically induced osteoarthritis in the rat results in the development of both osteoarthritis-like joint pain and secondary hyperalgesia.

Bove SE, Laemont KD, Brooker RM, Osborn MN, Sanchez BM, Guzman RE, Hook KE, Juneau PL, Connor JR, Kilgore KS.

Osteoarthritis Cartilage. 2006 Oct;14(10):1041-8. Epub 2006 Jun 12.

7.

Central role of complement membrane attack complex in monosodium urate crystal-induced neutrophilic rabbit knee synovitis.

Tramontini N, Huber C, Liu-Bryan R, Terkeltaub RA, Kilgore KS.

Arthritis Rheum. 2004 Aug;50(8):2633-9.

8.

In vivo micro computed tomography of subchondral bone in the rat after intra-articular administration of monosodium iodoacetate.

Morenko BJ, Bove SE, Chen L, Guzman RE, Juneau P, Bocan TM, Peter GK, Arora R, Kilgore KS.

Contemp Top Lab Anim Sci. 2004 Jan;43(1):39-43.

PMID:
14984289
9.

Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis.

Bove SE, Calcaterra SL, Brooker RM, Huber CM, Guzman RE, Juneau PL, Schrier DJ, Kilgore KS.

Osteoarthritis Cartilage. 2003 Nov;11(11):821-30.

10.

Modulation of leukocyte recruitment and IL-8 expression by the membrane attack complex of complement (C5b-9) in a rabbit model of antigen-induced arthritis.

Tramontini NL, Kuipers PJ, Huber CM, Murphy K, Naylor KB, Broady AJ, Kilgore KS.

Inflammation. 2002 Dec;26(6):311-9.

PMID:
12546141
11.

Role of inflammatory mediators in thrombogenesis.

Shebuski RJ, Kilgore KS.

J Pharmacol Exp Ther. 2002 Mar;300(3):729-35. Review.

PMID:
11861775
12.

Conditioned blood reperfusion during angioplasty (CoBRA) treatment of acute myocardial infarction.

Patel MB, Kilgore KS, Ortolano GA, Gryboski CL, Qureshi MA, Marcovitz P, Naylor KB, Park JL, Wenz B, Gikakis N, Freedman RJ Jr, Lucchesi BR, O'Neill WW.

Perfusion. 2001 Mar;16 Suppl:39-49.

PMID:
11334205
13.

Neutrophils and altered myocardial function.

Kilgore KS, Lucchesi BR.

Am Heart J. 2000 Jan;139(1 Pt 1):32-4. Review. No abstract available.

PMID:
10618559
14.

Delta opioid receptors and low temperature myocardial protection.

Schwartz CF, Georges AJ, Gallagher MA, Yu L, Kilgore KS, Bolling SF.

Ann Thorac Surg. 1999 Dec;68(6):2089-92.

PMID:
10616982
15.

Preconditioning reduces tissue complement gene expression in the rabbit isolated heart.

Tanhehco EJ, Yasojima K, McGeer PL, Washington RA, Kilgore KS, Homeister JW, Lucchesi BR.

Am J Physiol. 1999 Dec;277(6):H2373-80. doi: 10.1152/ajpheart.1999.277.6.H2373.

PMID:
10600858
16.

RSR13, a synthetic allosteric modifier of hemoglobin, improves myocardial recovery following hypothermic cardiopulmonary bypass.

Kilgore KS, Shwartz CF, Gallagher MA, Steffen RP, Mosca RS, Bolling SF.

Circulation. 1999 Nov 9;100(19 Suppl):II351-6.

PMID:
10567328
17.

The anti-factor D antibody, MAb 166-32, inhibits the alternative pathway of the human complement system.

Tanhehco EJ, Kilgore KS, Liff DA, Murphy KL, Fung MS, Sun WN, Sun C, Lucchesi BR.

Transplant Proc. 1999 Aug;31(5):2168-71. No abstract available.

PMID:
10456004
18.

Ex vivo reversal of heparin-mediated cardioprotection by heparinase after ischemia and reperfusion.

Kilgore KS, Tanhehco EJ, Naylor KB, Lucchesi BR.

J Pharmacol Exp Ther. 1999 Sep;290(3):1041-7.

PMID:
10454476
19.

Increased rat cardiac allograft survival by the glycosaminoglycan pentosan polysulfate.

Schwartz CF, Kilgore KS, Homeister JW, Levy BA, Lucchesi BR, Bolling SF.

J Surg Res. 1999 Sep;86(1):24-8.

PMID:
10452864
20.

Reduction of myocardial infarct size after ischemia and reperfusion by the glycosaminoglycan pentosan polysulfate.

Tanhehco EJ, Kilgore KS, Naylor KB, Park JL, Booth EA, Lucchesi BR.

J Cardiovasc Pharmacol. 1999 Jul;34(1):153-61.

PMID:
10413082
21.

N-Acetylheparin pretreatment reduces infarct size in the rabbit.

Park JL, Kilgore KS, Naylor KB, Booth EA, Murphy KL, Lucchesi BR.

Pharmacology. 1999 Mar;58(3):120-31.

PMID:
9925968
22.

Hibernation triggers and myocardial protection.

Bolling SF, Benedict MB, Tramontini NL, Kilgore KS, Harlow HH, Su TP, Oeltgen PR.

Circulation. 1998 Nov 10;98(19 Suppl):II220-3; discussion II223-4.

PMID:
9852906
24.

The carbohydrate sialyl Lewis(x) (sLe(x)) sulfated glycomimetic GM2941 attenuates glucan-induced pulmonary granulomatous vasculitis in the rat.

Kilgore KS, Powers KL, Imlay MM, Malani A, Allen DI, Beyer JT, Anderson MB, Warren JS.

J Pharmacol Exp Ther. 1998 Jul;286(1):439-46.

PMID:
9655889
25.

Postischemic function and protein kinase C signal transduction.

Rohs TJ, Kilgore KS, Georges AJ, Bolling SF.

Ann Thorac Surg. 1998 Jun;65(6):1680-4.

PMID:
9647081
26.

Complement gene expression by rabbit heart: upregulation by ischemia and reperfusion.

Yasojima K, Kilgore KS, Washington RA, Lucchesi BR, McGeer PL.

Circ Res. 1998 Jun 15;82(11):1224-30.

PMID:
9633921
27.

The semisynthetic polysaccharide pentosan polysulfate prevents complement-mediated myocardial injury in the rabbit perfused heart.

Kilgore KS, Naylor KB, Tanhehco EJ, Park JL, Booth EA, Washington RA, Lucchesi BR.

J Pharmacol Exp Ther. 1998 Jun;285(3):987-94.

PMID:
9618399
28.

Attenuation of interleukin-8 expression in C6-deficient rabbits after myocardial ischemia/reperfusion.

Kilgore KS, Park JL, Tanhehco EJ, Booth EA, Marks RM, Lucchesi BR.

J Mol Cell Cardiol. 1998 Jan;30(1):75-85.

PMID:
9500866
29.

Complement inhibitors in myocardial ischemia/reperfusion injury.

Lucchesi BR, Kilgore KS.

Immunopharmacology. 1997 Dec;38(1-2):27-42. Review.

PMID:
9476112
30.

Reduction of myocardial infarct size in vivo by carbohydrate-based glycomimetics.

Kilgore KS, Tanhehco EJ, Park JL, Naylor KB, Anderson MB, Lucchesi BR.

J Pharmacol Exp Ther. 1998 Jan;284(1):427-35.

PMID:
9435207
31.

Reviparin-sodium prevents complement-mediated myocardial injury in the isolated rabbit heart.

Park JL, Tanhehco EJ, Kilgore KS, Gralinski MR, Lucchesi BR.

J Cardiovasc Pharmacol. 1997 Nov;30(5):658-66.

PMID:
9388049
32.

Use of "natural" hibernation induction triggers for myocardial protection.

Bolling SF, Tramontini NL, Kilgore KS, Su TP, Oeltgen PR, Harlow HH.

Ann Thorac Surg. 1997 Sep;64(3):623-7.

PMID:
9307448
33.

Sublytic concentrations of the membrane attack complex of complement induce endothelial interleukin-8 and monocyte chemoattractant protein-1 through nuclear factor-kappa B activation.

Kilgore KS, Schmid E, Shanley TP, Flory CM, Maheswari V, Tramontini NL, Cohen H, Ward PA, Friedl HP, Warren JS.

Am J Pathol. 1997 Jun;150(6):2019-31.

34.

Neutrophils and reactive oxygen intermediates mediate glucan-induced pulmonary granuloma formation through the local induction of monocyte chemoattractant protein-1.

Kilgore KS, Imlay MM, Szaflarski JP, Silverstein FS, Malani AN, Evans VM, Warren JS.

Lab Invest. 1997 Feb;76(2):191-201.

PMID:
9042155
35.
36.

Heat stress protects the perfused rabbit heart from complement-mediated injury.

Gralinski MR, Black SC, Stancato LF, Kilgore KS, Campau PA, Park JL, Ozeck MJ, Pratt WB, Lucchesi BR.

Am J Physiol. 1996 Aug;271(2 Pt 2):H571-8.

PMID:
8770098
37.

Reduction of Myocardial Infarct Size in the Rabbit by a Carbohydrate Analog of Sialyl Lewis(x).

Kilgore KS, Park JL, Chi L, Musser JH, Date V V, Abbas S, Lucchesi BR.

J Cardiovasc Pharmacol Ther. 1996 Jan;1(1):49-56.

PMID:
10684399
38.

Antibodies to neutrophil cytoplasmic antigens induce monocyte chemoattractant protein-1 secretion from human monocytes.

Casselman BL, Kilgore KS, Miller BF, Warren JS.

J Lab Clin Med. 1995 Nov;126(5):495-502.

PMID:
7595035
39.
40.

Monoclonal antibody [7E3 F(ab')2] prevents arterial but not venous rethrombosis.

Sudo Y, Kilgore KS, Lucchesi BR.

J Cardiovasc Pharmacol. 1995 Aug;26(2):241-50.

PMID:
7475049
41.

Cardioprotective effects of heparin or N-acetylheparin in an in vivo model of myocardial ischaemic and reperfusion injury.

Black SC, Gralinski MR, Friedrichs GS, Kilgore KS, Driscoll EM, Lucchesi BR.

Cardiovasc Res. 1995 May;29(5):629-36.

PMID:
7606750
42.

Effects of heparin and N-acetyl heparin on ischemia/reperfusion-induced alterations in myocardial function in the rabbit isolated heart.

Friedrichs GS, Kilgore KS, Manley PJ, Gralinski MR, Lucchesi BR.

Circ Res. 1994 Oct;75(4):701-10.

PMID:
7923616
43.

Cardioprotective effects of ranolazine (RS-43285) in the isolated perfused rabbit heart.

Gralinski MR, Black SC, Kilgore KS, Chou AY, McCormack JG, Lucchesi BR.

Cardiovasc Res. 1994 Aug;28(8):1231-7.

PMID:
7954626
44.

Protective effects of the SOD-mimetic SC-52608 against ischemia/reperfusion damage in the rabbit isolated heart.

Kilgore KS, Friedrichs GS, Johnson CR, Schasteen CS, Riley DP, Weiss RH, Ryan U, Lucchesi BR.

J Mol Cell Cardiol. 1994 Aug;26(8):995-1006.

45.

The complement system in myocardial ischaemia/reperfusion injury.

Kilgore KS, Friedrichs GS, Homeister JW, Lucchesi BR.

Cardiovasc Res. 1994 Apr;28(4):437-44. Review. No abstract available.

PMID:
8181029
46.

Sulfhydryl compounds, captopril, and MPG inhibit complement-mediated myocardial injury.

Kilgore KS, Homeister JW, Satoh PS, Lucchesi BR.

Am J Physiol. 1994 Jan;266(1 Pt 2):H28-35.

PMID:
8304510
47.
48.
49.

Platelet GPIIb/IIIa receptor inhibition by SC-49992 prevents thrombosis and rethrombosis in the canine carotid artery.

Rote WE, Werns SW, Davis JH, Feigen LP, Kilgore KS, Lucchesi BR.

Cardiovasc Res. 1993 Mar;27(3):500-7.

PMID:
8490951
50.

Soluble complement receptor type 1 prevents human complement-mediated damage of the rabbit isolated heart.

Homeister JW, Satoh PS, Kilgore KS, Lucchesi BR.

J Immunol. 1993 Feb 1;150(3):1055-64.

PMID:
8423331

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