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Signaling incentive and drive in the primate ventral pallidum for motivational control of goal-directed action.

Fujimoto A, Hori Y, Nagai Y, Kikuchi E, Oyama K, Suhara T, Minamimoto T.

J Neurosci. 2019 Jan 9. pii: 2399-18. doi: 10.1523/JNEUROSCI.2399-18.2018. [Epub ahead of print]


Castration-resistant prostate cancer patients who had poor response on first androgen deprivation therapy would obtain certain clinical benefit from early docetaxel administration.

Shigeta K, Kosaka T, Hongo H, Yanai Y, Matsumoto K, Morita S, Mizuno R, Shinojima T, Kikuchi E, Oya M.

Int J Clin Oncol. 2019 Jan 2. doi: 10.1007/s10147-018-01388-5. [Epub ahead of print]


Glyoxalase 1 gene is highly expressed in basal-like human breast cancers and contributes to survival of ALDH1-positive breast cancer stem cells.

Tamori S, Nozaki Y, Motomura H, Nakane H, Katayama R, Onaga C, Kikuchi E, Shimada N, Suzuki Y, Noike M, Hara Y, Sato K, Sato T, Yamamoto K, Hanawa T, Imai M, Abe R, Yoshimori A, Takasawa R, Tanuma SI, Akimoto K.

Oncotarget. 2018 Nov 23;9(92):36515-36529. doi: 10.18632/oncotarget.26369. eCollection 2018 Nov 23.


Evaluation of prostate-specific antigen density in the diagnosis of prostate cancer combined with magnetic resonance imaging before biopsy in men aged 70 years and older with elevated PSA.

Yanai Y, Kosaka T, Hongo H, Matsumoto K, Shinojima T, Kikuchi E, Miyajima A, Mizuno R, Mikami S, Jinzaki M, Oya M.

Mol Clin Oncol. 2018 Dec;9(6):656-660. doi: 10.3892/mco.2018.1725. Epub 2018 Sep 19.


Immunoglobulin G4-Related Disease Arising from the Bladder Wall.

Kufukihara R, Niwa N, Mizuno R, Ohara K, Mikami S, Kikuchi E, Oya M.

Urol Int. 2018 Dec 13:1-3. doi: 10.1159/000495570. [Epub ahead of print]


Is transperitoneal laparoscopic radical nephrectomy suitable for patients with a history of abdominal surgery?

Yanai Y, Takeda T, Miyajima A, Matsumoto K, Hagiwara M, Mizuno R, Kikuchi E, Asanuma H, Oya M.

Asian J Endosc Surg. 2018 Dec 2. doi: 10.1111/ases.12673. [Epub ahead of print]


Long-Term Memory Engram Cells Are Established by c-Fos/CREB Transcriptional Cycling.

Miyashita T, Kikuchi E, Horiuchi J, Saitoe M.

Cell Rep. 2018 Dec 4;25(10):2716-2728.e3. doi: 10.1016/j.celrep.2018.11.022.


Single-cell RNA-seq analysis reveals the platinum resistance gene COX7B and the surrogate marker CD63.

Tanaka N, Katayama S, Reddy A, Nishimura K, Niwa N, Hongo H, Ogihara K, Kosaka T, Mizuno R, Kikuchi E, Mikami S, Miyakawa A, Arenas E, Kere J, Oya M, Uhlén P.

Cancer Med. 2018 Dec;7(12):6193-6204. doi: 10.1002/cam4.1828. Epub 2018 Oct 26.


ASO Author Reflections: PD-1 Expression in Bacillus Calmette-Guérin-Relapsing Bladder Cancer.

Fukumoto K, Kikuchi E.

Ann Surg Oncol. 2018 Dec;25(Suppl 3):982-983. doi: 10.1245/s10434-018-6949-9. Epub 2018 Oct 26. No abstract available.


Ureteral pseudodiverticulosis accompanied by urothelial carcinoma diagnosed by CT urography: a case report and review of the literature.

Sugiura H, Akita H, Kikuchi E, Mikami S, Hayakawa N, Narita K, Jinzaki M.

BJR Case Rep. 2018 Jan 18;4(2):20170111. doi: 10.1259/bjrcr.20170111. eCollection 2018.


No significant impact of patient age and prior treatment profile with docetaxel on the efficacy of cabazitaxel in patient with castration-resistant prostate cancer.

Kosaka T, Hongo H, Watanabe K, Mizuno R, Kikuchi E, Oya M.

Cancer Chemother Pharmacol. 2018 Dec;82(6):1061-1066. doi: 10.1007/s00280-018-3698-1. Epub 2018 Oct 3.


Performance of diffusion-weighted MRI post-CT urography for the diagnosis of upper tract urothelial carcinoma: Comparison with selective urine cytology sampling.

Akita H, Kikuchi E, Hayakawa N, Mikami S, Sugiura H, Oya M, Jinzaki M.

Clin Imaging. 2018 Nov - Dec;52:208-215. doi: 10.1016/j.clinimag.2018.08.012. Epub 2018 Aug 16.


Numb has distinct function in lung adenocarcinoma and squamous cell carcinoma.

Kikuchi H, Sakakibara-Konishi J, Furuta M, Kikuchi E, Kikuchi J, Oizumi S, Hida Y, Kaga K, Kinoshita I, Dosaka-Akita H, Nishimura M.

Oncotarget. 2018 Jun 29;9(50):29379-29391. doi: 10.18632/oncotarget.25585. eCollection 2018 Jun 29.


PKM2 under hypoxic environment causes resistance to mTOR inhibitor in human castration resistant prostate cancer.

Yasumizu Y, Hongo H, Kosaka T, Mikami S, Nishimoto K, Kikuchi E, Oya M.

Oncotarget. 2018 Jun 12;9(45):27698-27707. doi: 10.18632/oncotarget.25498. eCollection 2018 Jun 12.


History of Non-Muscle-Invasive Bladder Cancer May Have a Worse Prognostic Impact in cT2-4aN0M0 Bladder Cancer Patients Treated With Radical Cystectomy.

Kayama E, Kikuchi E, Fukumoto K, Shirotake S, Miyazaki Y, Hakozaki K, Kaneko G, Yoshimine S, Tanaka N, Takahiro M, Kanai K, Oyama M, Nakajima Y, Hara S, Monma T, Oya M.

Clin Genitourin Cancer. 2018 Oct;16(5):e969-e976. doi: 10.1016/j.clgc.2018.04.004. Epub 2018 Apr 28.


Establishment of the optimal follow-up schedule after radical prostatectomy.

Matsumoto K, Niwa N, Hattori S, Takeda T, Morita S, Kosaka T, Mizuno R, Shinojima T, Kikuchi E, Asanuma H, Oya M.

Urol Oncol. 2018 Jul;36(7):341.e9-341.e14. doi: 10.1016/j.urolonc.2018.04.003. Epub 2018 May 3.


Clinical Role of Programmed Cell Death-1 Expression in Patients with Non-muscle-invasive Bladder Cancer Recurring After Initial Bacillus Calmette-Guérin Therapy.

Fukumoto K, Kikuchi E, Mikami S, Hayakawa N, Matsumoto K, Niwa N, Oya M.

Ann Surg Oncol. 2018 Aug;25(8):2484-2491. doi: 10.1245/s10434-018-6498-2. Epub 2018 May 1.


Prognostic Value of Baseline Serum C-Reactive Protein Level in Intermediate-Risk Group Patients With Metastatic Renal-Cell Carcinoma Treated by First-Line Vascular Endothelial Growth Factor-Targeted Therapy.

Takamatsu K, Mizuno R, Omura M, Morita S, Matsumoto K, Shinoda K, Kosaka T, Takeda T, Shinojima T, Kikuchi E, Asanuma H, Oyama M, Mikami S, Oya M.

Clin Genitourin Cancer. 2018 Aug;16(4):e927-e933. doi: 10.1016/j.clgc.2018.03.012. Epub 2018 Mar 27.


Change of the 5α/5β ratio of urinary steroid metabolites in benign prostatic hyperplasia patients treated with dutasteride.

Maeda T, Kikuchi E, Hasegawa M, Homma K, Yasumizu Y, Hattori S, Kosaka T, Shinoda K, Miyajima A, Oya M.

Clin Biochem. 2018 May;55:36-41. doi: 10.1016/j.clinbiochem.2018.03.021. Epub 2018 Mar 31.


Incidence and timing of inadvertent nephrostomy catheter displacement in patients with ureteral obstruction

Niwa N, Matsumoto K, Kikuchi E, Yazawa S, Takeda T, Morita S, Kosaka T, Shinoda K, Mizuno R, Shinojima T, Asanuma H, Oya M.

Clin Nephrol. 2018 Aug;90(2):112-116. doi: 10.5414/CN109294.


Ancylostoma ceylanicum, novel etiological agent for traveler's diarrhea-report of four Japanese patients who returned from Southeast Asia and Papua New Guinea.

Yoshikawa M, Ouji Y, Hirai N, Nakamura-Uchiyama F, Yamada M, Arizono N, Akamatsu N, Yoh T, Kaya D, Nakatani T, Kikuchi E, Katanami Y, Satoh K, Maki R, Miyazato Y, Oba Y, Kasahara K, Mikasa K.

Trop Med Health. 2018 Mar 13;46:6. doi: 10.1186/s41182-018-0087-8. eCollection 2018.


A comparison of nephrotoxicity between patients with a solitary-functioning kidney and those with bilateral-functioning kidneys in cisplatin-based chemotherapy for advanced urothelial carcinoma: a Japanese retrospective multi-institutional study.

Inoue T, Miyazaki J, Ichioka D, Narita S, Kageyama S, Sugimoto M, Mitsuzuka K, Shiraishi Y, Kinoshita H, Wakeda H, Nomoto T, Kikuchi E, Matsui Y, Fujie K, Habuchi T, Nishiyama H.

BMC Cancer. 2018 Mar 14;18(1):290. doi: 10.1186/s12885-018-4186-z.


Vasohibin-1 as a novel microenvironmental biomarker for patient risk reclassification in low-risk prostate cancer.

Kobayashi H, Kosaka T, Mikami S, Miyazaki Y, Matsumoto K, Kikuchi E, Miyajima A, Kameyama K, Sato Y, Oya M.

Oncotarget. 2017 Dec 7;9(12):10203-10210. doi: 10.18632/oncotarget.23011. eCollection 2018 Feb 13.


Does switching the bacillus Calmette-Guérin strain affect clinical outcome in patients with recurrent non-muscle-invasive bladder cancer after initial bacillus Calmette-Guérin therapy?

Niwa N, Kikuchi E, Matsumoto K, Kosaka T, Mizuno R, Oya M.

Urol Oncol. 2018 Jun;36(6):306.e1-306.e8. doi: 10.1016/j.urolonc.2018.02.005. Epub 2018 Mar 9.


Successful Application of Edoxaban in the Treatment of Venous Thromboembolism Recurrence in a Patient with Non-small Cell Lung Cancer after Tumor Shrinkage.

Shoji T, Mizugaki H, Ikezawa Y, Furuta M, Takashima Y, Kikuchi H, Goudarzi H, Asahina H, Kikuchi J, Kikuchi E, Sakakibara-Konishi J, Shinagawa N, Tsujino I, Nishimura M.

Intern Med. 2018 Jun 15;57(12):1769-1772. doi: 10.2169/internalmedicine.9741-17. Epub 2018 Feb 9.


Variant isoforms of CD44 involves acquisition of chemoresistance to cisplatin and has potential as a novel indicator for identifying a cisplatin-resistant population in urothelial cancer.

Hagiwara M, Kikuchi E, Tanaka N, Kosaka T, Mikami S, Saya H, Oya M.

BMC Cancer. 2018 Jan 31;18(1):113. doi: 10.1186/s12885-018-3988-3.


Can urologists introduce the concept of "oligometastasis" for metastatic bladder cancer after total cystectomy?

Ogihara K, Kikuchi E, Watanabe K, Kufukihara R, Yanai Y, Takamatsu K, Matsumoto K, Hara S, Oyama M, Monma T, Masuda T, Hasegawa S, Oya M.

Oncotarget. 2017 Dec 4;8(67):111819-111835. doi: 10.18632/oncotarget.22911. eCollection 2017 Dec 19.


Purified Protein Derivative Skin test prior to bacillus Calmette-Guérin Therapy May have Therapeutic Impact in Patients with Nonmuscle Invasive Bladder Cancer.

Niwa N, Kikuchi E, Matsumoto K, Kosaka T, Mizuno R, Oya M.

J Urol. 2018 Jun;199(6):1446-1451. doi: 10.1016/j.juro.2017.12.057. Epub 2018 Jan 4.


Preoperative sarcopenia status is associated with lymphovascular invasion in upper tract urothelial carcinoma patients treated with radical nephroureterectomy.

Anno T, Kikuchi E, Fukumoto K, Ogihara K, Oya M.

Can Urol Assoc J. 2018 Mar;12(3):E132-E136. doi: 10.5489/cuaj.4786. Epub 2017 Dec 22.


Pre-operative and post-operative estimated glomerular filtration rate in Japanese patients with urological malignancies.

Niwa N, Yoshida T, Mizuno R, Kikuchi E, Miyajima A, Hayashi M, Oya M.

Clin Exp Nephrol. 2018 Oct;22(5):1205-1212. doi: 10.1007/s10157-017-1509-3. Epub 2017 Nov 27.


The Role of PD-1 Positivity in the Tumour Nest on Clinical Outcome in Upper Tract Urothelial Carcinoma Patients Treated with Radical Nephroureterectomy.

Hayakawa N, Kikuchi E, Mikami S, Fukumoto K, Oya M.

Clin Oncol (R Coll Radiol). 2018 Jan;30(1):e1-e8. doi: 10.1016/j.clon.2017.10.019. Epub 2017 Nov 15.


Purified protein derivative skin test reactions are associated with clinical outcomes of patients with nonmuscle invasive bladder cancer treated with induction bacillus Calmette-Guérin therapy.

Niwa N, Kikuchi E, Matsumoto K, Kosaka T, Mizuno R, Oya M.

Urol Oncol. 2018 Feb;36(2):77.e15-77.e21. doi: 10.1016/j.urolonc.2017.10.005. Epub 2017 Oct 31.


Significance of a frozen section analysis of the ureteral margin in bladder cancer patients treated with radical cystectomy and neoadjuvant chemotherapy.

Hakozaki K, Kikuchi E, Fukumoto K, Shirotake S, Miyazaki Y, Maeda T, Kaneko G, Yoshimine S, Tanaka N, Kanai K, Oyama M, Nakajima Y, Momma T, Oya M.

Med Oncol. 2017 Oct 23;34(12):187. doi: 10.1007/s12032-017-1048-5.


Factors influencing the operating time for single-port laparoscopic radical nephrectomy: focus on the anatomy and distribution of the renal artery and vein.

Matsumoto K, Miyajima A, Fukumoto K, Komatsuda A, Niwa N, Hattori S, Takeda T, Kikuchi E, Asanuma H, Oya M.

Jpn J Clin Oncol. 2017 Oct 1;47(10):976-980. doi: 10.1093/jjco/hyx105.


Baseline risk stratification or duration of prior therapy predicts prognosis in patients with metastatic renal cell carcinoma treated with axitinib.

Mizuno R, Mikami S, Takamatsu K, Shinojima T, Kikuchi E, Oya M.

Jpn J Clin Oncol. 2017 Dec 1;47(12):1170-1174. doi: 10.1093/jjco/hyx134.


Influence of dutasteride treatment on serum hormone levels and aging male symptoms in patients with benign prostatic enlargement.

Maeda T, Kikuchi E, Hasegawa M, Homma K, Ando T, Suzuki K, Kaneko G, Mizuno R, Miyajima A, Oya M.

Int J Urol. 2018 Jan;25(1):70-74. doi: 10.1111/iju.13470. Epub 2017 Oct 3.


Frequency and prognostic significance of incidental prostate cancer at radical cystectomy: Results from an international retrospective study.

Malte R, Kluth LA, Kaushik D, Boorjian SA, Abufaraj M, Foerster B, Rink M, Gust K, Roghmann F, Noldus J, Vordos D, Hagiwara M, Kikuchi E, Ikeda M, Matsumoto K, Karakiewicz PI, Rouprêt M, Briganti A, Scherr DS, Shariat SF, Seebacher V.

Eur J Surg Oncol. 2017 Nov;43(11):2193-2199. doi: 10.1016/j.ejso.2017.08.013. Epub 2017 Sep 7.


Drug-Repositioning Screening for Keap1-Nrf2 Binding Inhibitors using Fluorescence Correlation Spectroscopy.

Yoshizaki Y, Mori T, Ishigami-Yuasa M, Kikuchi E, Takahashi D, Zeniya M, Nomura N, Mori Y, Araki Y, Ando F, Mandai S, Kasagi Y, Arai Y, Sasaki E, Yoshida S, Kagechika H, Rai T, Uchida S, Sohara E.

Sci Rep. 2017 Jun 21;7(1):3945. doi: 10.1038/s41598-017-04233-3.


The Conditional Survival with Time of Intravesical Recurrence of Upper Tract Urothelial Carcinoma.

Shigeta K, Kikuchi E, Hagiwara M, Ando T, Mizuno R, Abe T, Mikami S, Miyajima A, Nakagawa K, Oya M.

J Urol. 2017 Dec;198(6):1278-1285. doi: 10.1016/j.juro.2017.06.073. Epub 2017 Jun 17.


Accumulation of porphyrins in Propionibacterium acnes by 5-aminolevulinic acid and its esters.

Ogata A, Hasunuma Y, Kikuchi E, Ishii T, Ishizuka M, Tokuoka Y.

Photodiagnosis Photodyn Ther. 2017 Sep;19:167-169. doi: 10.1016/j.pdpdt.2017.06.004. Epub 2017 Jun 15.


Development of WNK signaling inhibitors as a new class of antihypertensive drugs.

Ishigami-Yuasa M, Watanabe Y, Mori T, Masuno H, Fujii S, Kikuchi E, Uchida S, Kagechika H.

Bioorg Med Chem. 2017 Jul 15;25(14):3845-3852. doi: 10.1016/j.bmc.2017.05.034. Epub 2017 May 19.


Prognostic significance of erythrocyte protein band 4.1-like5 expression in upper urinary tract urothelial carcinoma.

Daimon T, Kosaka T, Kikuchi E, Mikami S, Miyazaki Y, Hashimoto A, Hashimoto S, Mizuno R, Miyajima A, Okada Y, Sabe H, Oya M.

Urol Oncol. 2017 Sep;35(9):543.e17-543.e24. doi: 10.1016/j.urolonc.2017.04.008. Epub 2017 May 5.


Impact of lymph node dissection on clinical outcomes during nephroureterectomy in patients with clinically node-negative upper urinary tract urothelial cancer: subanalysis of a multi-institutional nationwide case series of the Japanese Urological Association.

Inokuchi J, Eto M, Hara T, Fujimoto H, Nishiyama H, Miyazaki J, Kikuchi E, Hinotsu S, Koie T, Ohyama C; Cancer Registration Committee of the Japanese Urological Association.

Jpn J Clin Oncol. 2017 Jul 1;47(7):652-659. doi: 10.1093/jjco/hyx051.


Prolonged pneumoperitoneum time is an independent risk factor for intravesical recurrence after laparoscopic radical nephroureterectomy in upper tract urothelial carcinoma.

Shigeta K, Kikuchi E, Hagiwara M, Ando T, Mizuno R, Miyajima A, Nakagawa K, Oya M.

Surg Oncol. 2017 Mar;26(1):73-79. doi: 10.1016/j.suronc.2017.01.003. Epub 2017 Jan 23.


Obstructive sleep apnea syndrome should be considered as a cause of nocturia in younger patients without other voiding symptoms.

Maeda T, Fukunaga K, Nagata H, Haraguchi M, Kikuchi E, Miyajima A, Yamasawa W, Shirahama R, Narita M, Betsuyaku T, Asano K, Oya M.

Can Urol Assoc J. 2016 Jul-Aug;10(7-8):E241-E245. doi: 10.5489/cuaj.3508. Epub 2016 Jul 12.


Simple and practical nomograms for predicting the stone-free rate after shock wave lithotripsy in patients with a solitary upper ureteral stone.

Niwa N, Matsumoto K, Miyahara M, Omura M, Kobayashi H, Kikuchi E, Miyajima A, Miyata K, Oya M.

World J Urol. 2017 Sep;35(9):1455-1461. doi: 10.1007/s00345-017-2014-8. Epub 2017 Feb 20.


Impact of baseline visceral fat accumulation on prognosis in patients with metastatic renal cell carcinoma treated with systemic therapy.

Mizuno R, Miyajima A, Hibi T, Masuda A, Shinojima T, Kikuchi E, Jinzaki M, Oya M.

Med Oncol. 2017 Apr;34(4):47. doi: 10.1007/s12032-017-0908-3. Epub 2017 Feb 17.


Natural course of asymptomatic abnormal prostate findings incidentally detected by CT after intravesical BCG therapy.

Matsushima M, Kikuchi E, Akita H, Miyajima A, Oya M, Jinzaki M.

Int J Clin Oncol. 2017 Jun;22(3):554-562. doi: 10.1007/s10147-017-1096-z. Epub 2017 Feb 10.


Characterizing intermediate-risk non-muscle-invasive bladder cancer: Implications for the definition of intermediate risk and treatment strategy.

Matsumoto K, Kikuchi E, Yanai Y, Hayakawa N, Ito Y, Maeda T, Nagata H, Miyajima A, Oya M.

Urol Oncol. 2017 May;35(5):208-214. doi: 10.1016/j.urolonc.2016.11.014. Epub 2017 Jan 3.


Influence of physician years on urological journal publication productivity among Japanese urologists.

Niwa N, Kikuchi E, Matsumoto K, Miyajima A, Oya M.

Springerplus. 2016 Nov 29;5(1):2040. eCollection 2016.

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