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Items: 19


High mobility group box-1 (HMGB1) is increased in injured mouse spinal cord and can elicit neurotoxic inflammation.

Kigerl KA, Lai W, Wallace LM, Yang H, Popovich PG.

Brain Behav Immun. 2018 Aug;72:22-33. doi: 10.1016/j.bbi.2017.11.018. Epub 2017 Nov 23.


Gut Microbiota Are Disease-Modifying Factors After Traumatic Spinal Cord Injury.

Kigerl KA, Mostacada K, Popovich PG.

Neurotherapeutics. 2018 Jan;15(1):60-67. doi: 10.1007/s13311-017-0583-2. Review.


Gut dysbiosis impairs recovery after spinal cord injury.

Kigerl KA, Hall JC, Wang L, Mo X, Yu Z, Popovich PG.

J Exp Med. 2016 Nov 14;213(12):2603-2620. Epub 2016 Oct 17.


TLR4 Deficiency Impairs Oligodendrocyte Formation in the Injured Spinal Cord.

Church JS, Kigerl KA, Lerch JK, Popovich PG, McTigue DM.

J Neurosci. 2016 Jun 8;36(23):6352-64. doi: 10.1523/JNEUROSCI.0353-16.2016.


Traumatic spinal cord injury in mice with human immune systems.

Carpenter RS, Kigerl KA, Marbourg JM, Gaudet AD, Huey D, Niewiesk S, Popovich PG.

Exp Neurol. 2015 Sep;271:432-44. doi: 10.1016/j.expneurol.2015.07.011. Epub 2015 Jul 17.


Pattern recognition receptors and central nervous system repair.

Kigerl KA, de Rivero Vaccari JP, Dietrich WD, Popovich PG, Keane RW.

Exp Neurol. 2014 Aug;258:5-16. doi: 10.1016/j.expneurol.2014.01.001. Review.


p53 Regulates the neuronal intrinsic and extrinsic responses affecting the recovery of motor function following spinal cord injury.

Floriddia EM, Rathore KI, Tedeschi A, Quadrato G, Wuttke A, Lueckmann JM, Kigerl KA, Popovich PG, Di Giovanni S.

J Neurosci. 2012 Oct 3;32(40):13956-70. doi: 10.1523/JNEUROSCI.1925-12.2012.


Achieving CNS axon regeneration by manipulating convergent neuro-immune signaling.

Gensel JC, Kigerl KA, Mandrekar-Colucci SS, Gaudet AD, Popovich PG.

Cell Tissue Res. 2012 Jul;349(1):201-13. doi: 10.1007/s00441-012-1425-5. Epub 2012 May 17. Review.


Macrophage migration inhibitory factor (MIF) is essential for inflammatory and neuropathic pain and enhances pain in response to stress.

Alexander JK, Cox GM, Tian JB, Zha AM, Wei P, Kigerl KA, Reddy MK, Dagia NM, Sielecki T, Zhu MX, Satoskar AR, McTigue DM, Whitacre CC, Popovich PG.

Exp Neurol. 2012 Aug;236(2):351-62. doi: 10.1016/j.expneurol.2012.04.018. Epub 2012 May 1.


System x(c)(-) regulates microglia and macrophage glutamate excitotoxicity in vivo.

Kigerl KA, Ankeny DP, Garg SK, Wei P, Guan Z, Lai W, McTigue DM, Banerjee R, Popovich PG.

Exp Neurol. 2012 Jan;233(1):333-41. doi: 10.1016/j.expneurol.2011.10.025. Epub 2011 Nov 4.


Deficient CX3CR1 signaling promotes recovery after mouse spinal cord injury by limiting the recruitment and activation of Ly6Clo/iNOS+ macrophages.

Donnelly DJ, Longbrake EE, Shawler TM, Kigerl KA, Lai W, Tovar CA, Ransohoff RM, Popovich PG.

J Neurosci. 2011 Jul 6;31(27):9910-22. doi: 10.1523/JNEUROSCI.2114-11.2011.


Progranulin expression is upregulated after spinal contusion in mice.

Naphade SB, Kigerl KA, Jakeman LB, Kostyk SK, Popovich PG, Kuret J.

Acta Neuropathol. 2010 Jan;119(1):123-33. doi: 10.1007/s00401-009-0616-y. Epub 2009 Nov 28.


Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord.

Kigerl KA, Gensel JC, Ankeny DP, Alexander JK, Donnelly DJ, Popovich PG.

J Neurosci. 2009 Oct 28;29(43):13435-44. doi: 10.1523/JNEUROSCI.3257-09.2009.


Toll-like receptors in spinal cord injury.

Kigerl KA, Popovich PG.

Curr Top Microbiol Immunol. 2009;336:121-36. doi: 10.1007/978-3-642-00549-7_7. Review.


Stress exacerbates neuropathic pain via glucocorticoid and NMDA receptor activation.

Alexander JK, DeVries AC, Kigerl KA, Dahlman JM, Popovich PG.

Brain Behav Immun. 2009 Aug;23(6):851-60. doi: 10.1016/j.bbi.2009.04.001. Epub 2009 Apr 8.


Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury.

Kigerl KA, Lai W, Rivest S, Hart RP, Satoskar AR, Popovich PG.

J Neurochem. 2007 Jul;102(1):37-50. Epub 2007 Mar 30.


Invasive and angiogenic phenotype of MCF-7 human breast tumor cells expressing human cyclooxygenase-2.

Prosperi JR, Mallery SR, Kigerl KA, Erfurt AA, Robertson FM.

Prostaglandins Other Lipid Mediat. 2004 Apr;73(3-4):249-64.


Rats and mice exhibit distinct inflammatory reactions after spinal cord injury.

Sroga JM, Jones TB, Kigerl KA, McGaughy VM, Popovich PG.

J Comp Neurol. 2003 Jul 21;462(2):223-40.


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