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Items: 14

1.

Pharmacological Characterization of a Novel 5-Hydroxybenzothiazolone-Derived β 2-Adrenoceptor Agonist with Functional Selectivity for Anabolic Effects on Skeletal Muscle Resulting in a Wider Cardiovascular Safety Window in Preclinical Studies.

Koziczak-Holbro M, Rigel DF, Dumotier B, Sykes DA, Tsao J, Nguyen NH, Bösch J, Jourdain M, Flotte L, Adachi Y, Kiffe M, Azria M, Fairhurst RA, Charlton SJ, Richardson BP, Lach-Trifilieff E, Glass DJ, Ullrich T, Hatakeyama S.

J Pharmacol Exp Ther. 2019 May;369(2):188-199. doi: 10.1124/jpet.118.255307. Epub 2019 Feb 28.

PMID:
30819762
2.

Targeted inhibition of the COP9 signalosome for treatment of cancer.

Schlierf A, Altmann E, Quancard J, Jefferson AB, Assenberg R, Renatus M, Jones M, Hassiepen U, Schaefer M, Kiffe M, Weiss A, Wiesmann C, Sedrani R, Eder J, Martoglio B.

Nat Commun. 2016 Oct 24;7:13166. doi: 10.1038/ncomms13166.

3.

Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach.

Chen C, Zhu H, Stauffer F, Caravatti G, Vollmer S, Machauer R, Holzer P, Möbitz H, Scheufler C, Klumpp M, Tiedt R, Beyer KS, Calkins K, Guthy D, Kiffe M, Zhang J, Gaul C.

ACS Med Chem Lett. 2016 Jun 1;7(8):735-40. doi: 10.1021/acsmedchemlett.6b00167. eCollection 2016 Aug 11.

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SAR and pH stability of cyano-substituted epothilones.

Regueiro-Ren A, Leavitt K, Kim SH, Höfle G, Kiffe M, Gougoutas JZ, DiMarco JD, Lee FY, Fairchild CR, Long BH, Vite GD.

Org Lett. 2002 Oct 31;4(22):3815-8.

PMID:
12599466
11.

Derivatization of the C12-C13 functional groups of epothilones A, B and C.

Sefkow M, Kiffe M, Höfle G.

Bioorg Med Chem Lett. 1998 Nov 3;8(21):3031-6.

PMID:
9873670
12.

Oxidative and reductive transformations of epothilone A.

Sefkow M, Kiffe M, Schummer D, Höfle G.

Bioorg Med Chem Lett. 1998 Nov 3;8(21):3025-30.

PMID:
9873669
14.

[Twin births at the Universitaets-Frauenklinik Heidelberg 1950-1959].

BACH HG, KIFFE M.

Arch Gynakol. 1962;196:609-21. German. No abstract available.

PMID:
13863698

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