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Items: 1 to 50 of 144

1.

Bacterial Cell Wall Modification with a Glycolipid Substrate.

Calabretta PJ, Hodges HL, Kraft MB, Marando VM, Kiessling LL.

J Am Chem Soc. 2019 Jun 12;141(23):9262-9272. doi: 10.1021/jacs.9b02290. Epub 2019 Jun 4.

PMID:
31081628
2.

Angiomotin Regulates YAP Localization during Neural Differentiation of Human Pluripotent Stem Cells.

Zaltsman Y, Masuko S, Bensen JJ, Kiessling LL.

Stem Cell Reports. 2019 May 14;12(5):869-877. doi: 10.1016/j.stemcr.2019.03.009. Epub 2019 Apr 18.

3.

Chemoselective, Postpolymerization Modification of Bioactive, Degradable Polymers.

Fishman JM, Zwick DB, Kruger AG, Kiessling LL.

Biomacromolecules. 2019 Feb 11;20(2):1018-1027. doi: 10.1021/acs.biomac.8b01631. Epub 2019 Jan 22.

PMID:
30608163
4.

Chemistry-driven glycoscience.

Kiessling LL.

Bioorg Med Chem. 2018 Oct 15;26(19):5229-5238. doi: 10.1016/j.bmc.2018.09.024. Epub 2018 Sep 22.

PMID:
30297120
5.

Polymers at the Interface with Biology.

Deming TJ, Klok HA, Armes SP, Becker ML, Champion JA, Chen EY, Heilshorn SC, van Hest JCM, Irvine DJ, Johnson JA, Kiessling LL, Maynard HD, de la Cruz MO, Sullivan MO, Tirrell MV, Anseth KS, Lecommandoux S, Percec S, Zhong Z, Albertsson AC.

Biomacromolecules. 2018 Aug 13;19(8):3151-3162. doi: 10.1021/acs.biomac.8b01029. No abstract available.

PMID:
30099879
6.

Imaging mycobacterial growth and division with a fluorogenic probe.

Hodges HL, Brown RA, Crooks JA, Weibel DB, Kiessling LL.

Proc Natl Acad Sci U S A. 2018 May 15;115(20):5271-5276. doi: 10.1073/pnas.1720996115. Epub 2018 Apr 27.

7.

Spotlight: A Conversation with Laura Kiessling and Jennifer Doudna.

Kiessling LL, Doudna JA.

ACS Chem Biol. 2018 Feb 16;13(2):290-295. doi: 10.1021/acschembio.8b00108.

PMID:
29448761
8.

How many human proteoforms are there?

Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, Ivanov AR, Jensen ON, Jewett MC, Kelleher NL, Kiessling LL, Krogan NJ, Larsen MR, Loo JA, Ogorzalek Loo RR, Lundberg E, MacCoss MJ, Mallick P, Mootha VK, Mrksich M, Muir TW, Patrie SM, Pesavento JJ, Pitteri SJ, Rodriguez H, Saghatelian A, Sandoval W, Schlüter H, Sechi S, Slavoff SA, Smith LM, Snyder MP, Thomas PM, Uhlén M, Van Eyk JE, Vidal M, Walt DR, White FM, Williams ER, Wohlschlager T, Wysocki VH, Yates NA, Young NL, Zhang B.

Nat Chem Biol. 2018 Feb 14;14(3):206-214. doi: 10.1038/nchembio.2576.

9.

Taxation on Innovation.

Weidmann AG, Kiessling LL.

ACS Chem Biol. 2017 Dec 15;12(12):2915. doi: 10.1021/acschembio.7b01044. No abstract available.

PMID:
29241335
10.

Deleterious Consequences of UDP-Galactopyranose Mutase Inhibition for Nematodes.

Winton VJ, Justen AM, Deng H, Kiessling LL.

ACS Chem Biol. 2017 Sep 15;12(9):2354-2361. doi: 10.1021/acschembio.7b00487. Epub 2017 Aug 16.

11.

Conformational Control of UDP-Galactopyranose Mutase Inhibition.

Wangkanont K, Winton VJ, Forest KT, Kiessling LL.

Biochemistry. 2017 Aug 1;56(30):3983-3992. doi: 10.1021/acs.biochem.7b00189. Epub 2017 Jul 20.

12.

Recognition of microbial glycans by soluble human lectins.

Wesener DA, Dugan A, Kiessling LL.

Curr Opin Struct Biol. 2017 Jun;44:168-178. doi: 10.1016/j.sbi.2017.04.002. Epub 2017 May 5. Review.

PMID:
28482337
13.

Nanoscience and Nanotechnology Cross Borders.

Khademhosseini A, Chan WW, Chhowalla M, Glotzer SC, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Kotov NA, Lee ST, Li Y, Möhwald H, Mulvaney PA, Nel AE, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Brinker J, Chen X, Chi L, Crommie M, Dekker C, Farokhzad O, Gerber C, Ginger DS, Irvine DJ, Kiessling LL, Kostarelos K, Landes C, Lee T, Leggett GJ, Liang XJ, Liz-Marzán L, Millstone J, Odom TW, Ozcan A, Prato M, Rao CN, Sailor MJ, Weiss E, Weiss PS.

ACS Nano. 2017 Feb 28;11(2):1123-1126. doi: 10.1021/acsnano.7b00953. Epub 2017 Feb 15. No abstract available.

PMID:
28199099
14.

Comparing Galactan Biosynthesis in Mycobacterium tuberculosis and Corynebacterium diphtheriae.

Wesener DA, Levengood MR, Kiessling LL.

J Biol Chem. 2017 Feb 17;292(7):2944-2955. doi: 10.1074/jbc.M116.759340. Epub 2016 Dec 30.

15.

ChemRXiv: A Chemistry Preprint Server.

Kiessling LL, Fernandez LE, Alivisatos AP, Weiss PS.

ACS Chem Biol. 2016 Nov 18;11(11):2937. No abstract available.

PMID:
27933802
16.

ChemRXiv: A Chemistry Preprint Server.

Kiessling LL, Fernandez LE, Alivisatos AP, Weiss PS.

ACS Nano. 2016 Oct 25;10(10):9053-9054. No abstract available.

PMID:
27776406
17.

Carboxylate Surrogates Enhance the Antimycobacterial Activity of UDP-Galactopyranose Mutase Probes.

Winton VJ, Aldrich C, Kiessling LL.

ACS Infect Dis. 2016 Aug 12;2(8):538-43. doi: 10.1021/acsinfecdis.6b00021. Epub 2016 Jun 29.

18.

Fidelity and Promiscuity of a Mycobacterial Glycosyltransferase.

Yamatsugu K, Splain RA, Kiessling LL.

J Am Chem Soc. 2016 Jul 27;138(29):9205-11. doi: 10.1021/jacs.6b04481. Epub 2016 Jul 13.

19.

Bioconjugates and Chemical Biology.

Kiessling LL, Rotello VM.

Bioconjug Chem. 2016 Jun 15;27(6):1429. doi: 10.1021/acs.bioconjchem.6b00289. No abstract available.

PMID:
27301428
20.

Focus on Epigenetics.

Kutateladze TG, Kiessling LL.

ACS Chem Biol. 2016 Mar 18;11(3):541-2. doi: 10.1021/acschembio.6b00218. No abstract available.

PMID:
26987448
21.

Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition.

Wangkanont K, Wesener DA, Vidani JA, Kiessling LL, Forest KT.

J Biol Chem. 2016 Mar 11;291(11):5596-610. doi: 10.1074/jbc.M115.709212. Epub 2016 Jan 11.

22.

Carbohydrate-Aromatic Interactions in Proteins.

Hudson KL, Bartlett GJ, Diehl RC, Agirre J, Gallagher T, Kiessling LL, Woolfson DN.

J Am Chem Soc. 2015 Dec 9;137(48):15152-60. doi: 10.1021/jacs.5b08424. Epub 2015 Nov 30.

23.

Virtual Screening for UDP-Galactopyranose Mutase Ligands Identifies a New Class of Antimycobacterial Agents.

Kincaid VA, London N, Wangkanont K, Wesener DA, Marcus SA, Héroux A, Nedyalkova L, Talaat AM, Forest KT, Shoichet BK, Kiessling LL.

ACS Chem Biol. 2015 Oct 16;10(10):2209-18. doi: 10.1021/acschembio.5b00370. Epub 2015 Aug 17.

24.

Recognition of microbial glycans by human intelectin-1.

Wesener DA, Wangkanont K, McBride R, Song X, Kraft MB, Hodges HL, Zarling LC, Splain RA, Smith DF, Cummings RD, Paulson JC, Forest KT, Kiessling LL.

Nat Struct Mol Biol. 2015 Aug;22(8):603-10. doi: 10.1038/nsmb.3053. Epub 2015 Jul 6.

25.

The non-detergent sulfobetaine-201 acts as a pharmacological chaperone to promote folding and crystallization of the type II TGF-β receptor extracellular domain.

Wangkanont K, Forest KT, Kiessling LL.

Protein Expr Purif. 2015 Nov;115:19-25. doi: 10.1016/j.pep.2015.06.001. Epub 2015 Jun 11.

26.

Multivalent Antigens for Promoting B and T Cell Activation.

Bennett NR, Zwick DB, Courtney AH, Kiessling LL.

ACS Chem Biol. 2015 Aug 21;10(8):1817-24. doi: 10.1021/acschembio.5b00239. Epub 2015 Jun 2.

27.

Forces of Change: Mechanics Underlying Formation of Functional 3D Organ Buds.

Wrighton PJ, Kiessling LL.

Cell Stem Cell. 2015 May 7;16(5):453-4. doi: 10.1016/j.stem.2015.04.018.

28.

Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins.

Wrighton PJ, Klim JR, Hernandez BA, Koonce CH, Kamp TJ, Kiessling LL.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18126-31. doi: 10.1073/pnas.1409525111. Epub 2014 Nov 24.

29.

Polyspecific pyrrolysyl-tRNA synthetases from directed evolution.

Guo LT, Wang YS, Nakamura A, Eiler D, Kavran JM, Wong M, Kiessling LL, Steitz TA, O'Donoghue P, Söll D.

Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16724-9. doi: 10.1073/pnas.1419737111. Epub 2014 Nov 10.

30.

Substratum-induced differentiation of human pluripotent stem cells reveals the coactivator YAP is a potent regulator of neuronal specification.

Musah S, Wrighton PJ, Zaltsman Y, Zhong X, Zorn S, Parlato MB, Hsiao C, Palecek SP, Chang Q, Murphy WL, Kiessling LL.

Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13805-10. doi: 10.1073/pnas.1415330111. Epub 2014 Sep 8.

31.

A symposium in honor of Peter B. Dervan, the 2014 ACS Chemical Biology Lectureship Award Winner.

Soares JA, Kiessling LL.

ACS Chem Biol. 2014 Jun 20;9(6):1221-3. doi: 10.1021/cb5003703. No abstract available.

PMID:
25120068
32.

Rhamnose glycoconjugates for the recruitment of endogenous anti-carbohydrate antibodies to tumor cells.

Sheridan RT, Hudon J, Hank JA, Sondel PM, Kiessling LL.

Chembiochem. 2014 Jul 7;15(10):1393-8. doi: 10.1002/cbic.201402019. Epub 2014 Jun 6.

33.

Isoprenoid phosphonophosphates as glycosyltransferase acceptor substrates.

Martinez Farias MA, Kincaid VA, Annamalai VR, Kiessling LL.

J Am Chem Soc. 2014 Jun 18;136(24):8492-5. doi: 10.1021/ja500622v. Epub 2014 Jun 10.

34.

New insights into bacterial chemoreceptor array structure and assembly from electron cryotomography.

Briegel A, Wong ML, Hodges HL, Oikonomou CM, Piasta KN, Harris MJ, Fowler DJ, Thompson LK, Falke JJ, Kiessling LL, Jensen GJ.

Biochemistry. 2014 Mar 18;53(10):1575-85. doi: 10.1021/bi5000614. Epub 2014 Mar 6. Erratum in: Biochemistry. 2014 Oct 21;53(41):6624.

35.

Synthetic antigens reveal dynamics of BCR endocytosis during inhibitory signaling.

Courtney AH, Bennett NR, Zwick DB, Hudon J, Kiessling LL.

ACS Chem Biol. 2014 Jan 17;9(1):202-10. doi: 10.1021/cb400532y. Epub 2013 Nov 14.

36.

Chemistry. A path to complex carbohydrates.

Kiessling LL, Kraft MB.

Science. 2013 Jul 26;341(6144):357-8. doi: 10.1126/science.1241788. No abstract available.

PMID:
23888030
37.

UDP-galactopyranose mutase in nematodes.

Wesener DA, May JF, Huffman EM, Kiessling LL.

Biochemistry. 2013 Jun 25;52(25):4391-8. doi: 10.1021/bi400264d. Epub 2013 Jun 11.

38.

Glycopolymer probes of signal transduction.

Kiessling LL, Grim JC.

Chem Soc Rev. 2013 May 21;42(10):4476-91. doi: 10.1039/c3cs60097a. Epub 2013 Apr 18. Review.

39.

Synthesis of functionalizable and degradable polymers by ring-opening metathesis polymerization.

Fishman JM, Kiessling LL.

Angew Chem Int Ed Engl. 2013 May 3;52(19):5061-4. doi: 10.1002/anie.201300293. Epub 2013 Apr 8. No abstract available.

40.

Synthesis of lipid-linked arabinofuranose donors for glycosyltransferases.

Kraft MB, Martinez Farias MA, Kiessling LL.

J Org Chem. 2013 Mar 1;78(5):2128-33. doi: 10.1021/jo302507p. Epub 2013 Feb 7.

41.

Glycosaminoglycan-binding hydrogels enable mechanical control of human pluripotent stem cell self-renewal.

Musah S, Morin SA, Wrighton PJ, Zwick DB, Jin S, Kiessling LL.

ACS Nano. 2012 Nov 27;6(11):10168-77. doi: 10.1021/nn3039148. Epub 2012 Oct 1.

42.

Noncarbohydrate glycomimetics and glycoprotein surrogates as DC-SIGN antagonists and agonists.

Prost LR, Grim JC, Tonelli M, Kiessling LL.

ACS Chem Biol. 2012 Sep 21;7(9):1603-8. Epub 2012 Jul 19.

43.

Quinoxalinone Inhibitors of the Lectin DC-SIGN.

Mangold SL, Prost LR, Kiessling LL.

Chem Sci. 2012 Mar;3(3):772-777. Epub 2011 Nov 24.

44.

Fluorosugar chain termination agents as probes of the sequence specificity of a carbohydrate polymerase.

Brown CD, Rusek MS, Kiessling LL.

J Am Chem Soc. 2012 Apr 18;134(15):6552-5. doi: 10.1021/ja301723p. Epub 2012 Apr 10.

45.

An asymmetric synthesis of L-pyrrolysine.

Wong ML, Guzei IA, Kiessling LL.

Org Lett. 2012 Mar 16;14(6):1378-81. doi: 10.1021/ol300045c. Epub 2012 Mar 6.

46.

A processive carbohydrate polymerase that mediates bifunctional catalysis using a single active site.

May JF, Levengood MR, Splain RA, Brown CD, Kiessling LL.

Biochemistry. 2012 Feb 14;51(6):1148-59. doi: 10.1021/bi201820p. Epub 2012 Feb 3.

47.

Small-molecule-modified surfaces engage cells through the αvβ3 integrin.

Klim JR, Fowler AJ, Courtney AH, Wrighton PJ, Sheridan RT, Wong ML, Kiessling LL.

ACS Chem Biol. 2012 Mar 16;7(3):518-25. doi: 10.1021/cb2004725. Epub 2012 Jan 26.

48.

Monitoring processivity and length control of a carbohydrate polymerase.

Levengood MR, Splain RA, Kiessling LL.

J Am Chem Soc. 2011 Aug 17;133(32):12758-66. doi: 10.1021/ja204448t. Epub 2011 Jul 25.

49.

Spatial control of cell fate using synthetic surfaces to potentiate TGF-beta signaling.

Li L, Klim JR, Derda R, Courtney AH, Kiessling LL.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11745-50. doi: 10.1073/pnas.1101454108. Epub 2011 Jun 30.

50.

Glycomimetic building blocks: a divergent synthesis of epimers of shikimic acid.

Grim JC, Garber KC, Kiessling LL.

Org Lett. 2011 Aug 5;13(15):3790-3. doi: 10.1021/ol201252x. Epub 2011 Jun 28.

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