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Single-dose diclofenac in healthy volunteers can cause decrease in renal perfusion measured by functional magnetic resonance imaging.

Hellms S, Gueler F, Gutberlet M, Schebb NH, Rund K, Kielstein JT, VoChieu V, Rauhut S, Greite R, Martirosian P, Haller H, Wacker F, Derlin K.

J Pharm Pharmacol. 2019 Aug;71(8):1262-1270. doi: 10.1111/jphp.13105. Epub 2019 May 27.


The MATRIX trial.

Meyer TM, Hollenbeck M, Kielstein JT.

Lancet. 2019 May 4;393(10183):1802-1803. doi: 10.1016/S0140-6736(19)30040-6. No abstract available.


Outcomes of renal dysfunction in patients with acute liver failure.

Hadem J, Kielstein JT, Manns MP, Kümpers P, Lukasz A.

United European Gastroenterol J. 2019 Apr;7(3):388-396. doi: 10.1177/2050640618817061. Epub 2018 Dec 3.


Single- and multiple-dose pharmacokinetics and total removal of colistin in critically ill patients with acute kidney injury undergoing prolonged intermittent renal replacement therapy.

Schmidt JJ, Strunk AK, David S, Bode-Böger SM, Martens-Lobenhoffer J, Knitsch W, Scherneck S, Welte T, Kielstein JT.

J Antimicrob Chemother. 2019 Apr 1;74(4):997-1002. doi: 10.1093/jac/dky511.


Drugs linked to plasma homoarginine in chronic kidney disease patients-a cross-sectional analysis of the German Chronic Kidney Disease cohort.

Maas R, Mieth M, Titze SI, Hübner S, Fromm MF, Kielstein JT, Schmid M, Köttgen A, Kronenberg F, Krane V, Hausknecht B, Eckardt KU, Schneider MP; GCKD study investigators .

Nephrol Dial Transplant. 2018 Nov 23. doi: 10.1093/ndt/gfy342. [Epub ahead of print]


Early therapeutic plasma exchange in septic shock: a prospective open-label nonrandomized pilot study focusing on safety, hemodynamics, vascular barrier function, and biologic markers.

Knaup H, Stahl K, Schmidt BMW, Idowu TO, Busch M, Wiesner O, Welte T, Haller H, Kielstein JT, Hoeper MM, David S.

Crit Care. 2018 Oct 30;22(1):285. doi: 10.1186/s13054-018-2220-9.


Improved short- and long-term outcome of allogeneic stem cell recipients admitted to the intensive care unit: a retrospective longitudinal analysis of 942 patients.

Lueck C, Stadler M, Koenecke C, Hoeper MM, Dammann E, Schneider A, Kielstein JT, Ganser A, Eder M, Beutel G.

Intensive Care Med. 2018 Sep;44(9):1483-1492. doi: 10.1007/s00134-018-5347-x. Epub 2018 Aug 23.


Higher levels of SDMA and not ADMA are associated with poorer survival of trial patients with systemic ANCA-associated vasculitis.

Erdbrügger U, Kielstein JT, Westman K, Ma JZ, Xin W, Bode-Böger SM, Segelmark M, Rasmussen N, De Groot K.

Eur J Rheumatol. 2018 Sep;5(3):153-159. doi: 10.5152/eurjrheum.2018.17119. Epub 2018 Apr 2.


Preoperative serum uric acid predicts incident acute kidney injury following cardiac surgery.

Kaufeld T, Foerster KA, Schilling T, Kielstein JT, Kaufeld J, Shrestha M, Haller HG, Haverich A, Schmidt BMW.

BMC Nephrol. 2018 Jul 4;19(1):161. doi: 10.1186/s12882-018-0970-x.


[Prevention of acute kidney injury in critically ill patients : Recommendations from the renal section of the DGIIN, ÖGIAIN and DIVI].

Joannidis M, Klein SJ, John S, Schmitz M, Czock D, Druml W, Jörres A, Kindgen-Milles D, Kielstein JT, Oppert M, Schwenger V, Willam C, Zarbock A.

Med Klin Intensivmed Notfmed. 2018 Jun;113(5):358-369. doi: 10.1007/s00063-018-0413-2. Epub 2018 Mar 28. Review. German.


[Dose adjustment of anti-infective drugs in patients with renal failure and renal replacement therapy in intensive care medicine : Recommendations from the renal section of the DGIIN, ÖGIAIN and DIVI].

Czock D, Schwenger V, Kindgen-Milles D, Joannidis M, John S, Schmitz M, Jörres A, Zarbock A, Oppert M, Kielstein JT, Willam C.

Med Klin Intensivmed Notfmed. 2018 Jun;113(5):384-392. doi: 10.1007/s00063-018-0416-z. Epub 2018 Mar 15. Review. German.


[Extracorporeal renal replacement therapy in acute kidney injury : Recommendations from the renal section of the DGIIN, ÖGIAIN and DIVI].

Schwenger V, Kindgen-Milles D, Willam C, Jörres A, Druml W, Czock D, Klein SJ, Oppert M, Schmitz M, Kielstein JT, Zarbock A, Joannidis M, John S.

Med Klin Intensivmed Notfmed. 2018 Jun;113(5):370-376. doi: 10.1007/s00063-018-0418-x. Epub 2018 Mar 15. Review. German.


Population pharmacokinetics of vancomycin in critically ill patients receiving prolonged intermittent renal replacement therapy.

Economou CJP, Kielstein JT, Czock D, Xie J, Field J, Richards B, Tallott M, Visser A, Koenig C, Hafer C, Schmidt JJ, Lipman J, Roberts JA.

Int J Antimicrob Agents. 2018 Aug;52(2):151-157. doi: 10.1016/j.ijantimicag.2018.03.001. Epub 2018 Mar 9.


Hypoxia-induced long non-coding RNA Malat1 is dispensable for renal ischemia/reperfusion-injury.

Kölling M, Genschel C, Kaucsar T, Hübner A, Rong S, Schmitt R, Sörensen-Zender I, Haddad G, Kistler A, Seeger H, Kielstein JT, Fliser D, Haller H, Wüthrich R, Zörnig M, Thum T, Lorenzen J.

Sci Rep. 2018 Feb 21;8(1):3438. doi: 10.1038/s41598-018-21720-3.


Therapeutic plasma exchange in a tertiary care center: 185 patients undergoing 912 treatments - a one-year retrospective analysis.

Schmidt JJ, Asper F, Einecke G, Eden G, Hafer C, Kielstein JT.

BMC Nephrol. 2018 Jan 15;19(1):12. doi: 10.1186/s12882-017-0803-3.


Enhanced elimination of cyclophosphamide by high cut-off haemodialysis: single-dose pharmacokinetics in a patient with cast nephropathy.

Eden G, Kühn-Velten WN, Hafer C, Kielstein JT.

BMJ Case Rep. 2018 Jan 4;2018. pii: bcr-2017-221735. doi: 10.1136/bcr-2017-221735.


Dimethylarginines in patients with intracerebral hemorrhage: association with outcome, hematoma enlargement, and edema.

Worthmann H, Li N, Martens-Lobenhoffer J, Dirks M, Schuppner R, Lichtinghagen R, Kielstein JT, Raab P, Lanfermann H, Bode-Böger SM, Weissenborn K.

J Neuroinflammation. 2017 Dec 13;14(1):247. doi: 10.1186/s12974-017-1016-1.


Opponent's comments.

Hafer C, Kielstein JT.

Nephrol Dial Transplant. 2017 Sep 1;32(9):1463-1464. doi: 10.1093/ndt/gfx090a. No abstract available.


Pro: High dose of therapeutic plasma exchange-mind the gap!

Hafer C, Kielstein JT.

Nephrol Dial Transplant. 2017 Sep 1;32(9):1457-1460. doi: 10.1093/ndt/gfx084.


International registry on the use of the CytoSorb® adsorber in ICU patients : Study protocol and preliminary results.

Friesecke S, Träger K, Schittek GA, Molnar Z, Bach F, Kogelmann K, Bogdanski R, Weyland A, Nierhaus A, Nestler F, Olboeter D, Tomescu D, Jacob D, Haake H, Grigoryev E, Nitsch M, Baumann A, Quintel M, Schott M, Kielstein JT, Meier-Hellmann A, Born F, Schumacher U, Singer M, Kellum J, Brunkhorst FM.

Med Klin Intensivmed Notfmed. 2017 Sep 4. doi: 10.1007/s00063-017-0342-5. [Epub ahead of print] Review.


[Hot rods in the ICU : What is the antibiotic mileage of your renal replacement therapy?]

Kielstein JT, Kruse AK, Anderson N, Vaitiekunas H, Scherneck S.

Med Klin Intensivmed Notfmed. 2019 Mar;114(2):139-145. doi: 10.1007/s00063-017-0303-z. Epub 2017 May 8. Review. German.


Have renal biomarkers failed in acute kidney injury? Yes.

Vanmassenhove J, Kielstein JT, Ostermann M.

Intensive Care Med. 2017 Jun;43(6):883-886. doi: 10.1007/s00134-017-4759-3. Epub 2017 Apr 24. No abstract available.


A comparative study of bone biopsies from the iliac crest, the tibial bone, and the lumbar spine.

Hiller RG, Patecki M, Neunaber C, Reifenrath J, Kielstein JT, Kielstein H.

BMC Nephrol. 2017 Apr 13;18(1):134. doi: 10.1186/s12882-017-0550-5.


The answer is blowing in the wind: an uncommon cause for severe ARDS accompanied by circulatory insufficiency requiring extracorporeal membrane oxygenation.

Einecke G, Beutel G, Hoeper MM, Kielstein JT.

BMJ Case Rep. 2017 Mar 24;2017. pii: bcr2016218079. doi: 10.1136/bcr-2016-218079.


[Acute kidney injury from intravenous immunoglobulins - an avoidable complication].

Hansen-Hagge C, Bräsen JH, Kielstein JT.

Z Rheumatol. 2017 Apr;76(3):279-280. doi: 10.1007/s00393-017-0273-9. German. No abstract available.


Effect of extracorporeal cytokine removal on vascular barrier function in a septic shock patient.

David S, Thamm K, Schmidt BMW, Falk CS, Kielstein JT.

J Intensive Care. 2017 Jan 21;5:12. doi: 10.1186/s40560-017-0208-1. eCollection 2017.


Therapy of Treatment-Related Hypertension in Metastatic Renal-Cell Cancer Patients Receiving Sunitinib.

Ivanyi P, Beutel G, Drewes N, Pirr J, Kielstein JT, Morgan M, Ganser A, Grünwald V.

Clin Genitourin Cancer. 2017 Apr;15(2):280-290.e3. doi: 10.1016/j.clgc.2016.10.004. Epub 2016 Oct 19.


[Role of plasmapheresis and immunoadsorption in salvage therapy of rheumatological diseases].

Boser M, Kielstein JT.

Z Rheumatol. 2016 Dec;75(10):964-972. Review. German.


[Therapeutic plasma exchange for the treatment of hypertriglyceridemia-induced pancreatitis : A case report].

Eden G, Gradaus F, Brown K, Gauert I, Sass C, Kielstein JT.

Med Klin Intensivmed Notfmed. 2017 Jun;112(5):471-474. doi: 10.1007/s00063-016-0219-z. Epub 2016 Sep 27. German.


Clinical and Laboratory Consequences of Platelet Transfusion in Shiga Toxin-Mediated Hemolytic Uremic Syndrome.

Beneke J, Sartison A, Kielstein JT, Haller H, Nitschke M, Kunzendorf U, Loos S, Kemper MJ, Stahl RA, Menne J; German 2011 STEC-HUS outbreak study group.

Transfus Med Rev. 2017 Jan;31(1):51-55. doi: 10.1016/j.tmrv.2016.06.004. Epub 2016 Jun 21.


Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies.

Sekula P, Li Y, Stanescu HC, Wuttke M, Ekici AB, Bockenhauer D, Walz G, Powis SH, Kielstein JT, Brenchley P; GCKD Investigators, Eckardt KU, Kronenberg F, Kleta R, Köttgen A.

Nephrol Dial Transplant. 2017 Feb 1;32(2):325-332. doi: 10.1093/ndt/gfw001. Epub 2016 Feb 4.


Glycaemic control and antidiabetic therapy in patients with diabetes mellitus and chronic kidney disease - cross-sectional data from the German Chronic Kidney Disease (GCKD) cohort.

Busch M, Nadal J, Schmid M, Paul K, Titze S, Hübner S, Köttgen A, Schultheiss UT, Baid-Agrawal S, Lorenzen J, Schlieper G, Sommerer C, Krane V, Hilge R, Kielstein JT, Kronenberg F, Wanner C, Eckardt KU, Wolf G; GCKD Study Investigators.

BMC Nephrol. 2016 Jun 11;17(1):59. doi: 10.1186/s12882-016-0273-z.


Health status, renal function, and quality of life after multiorgan failure and acute kidney injury requiring renal replacement therapy.

Faulhaber-Walter R, Scholz S, Haller H, Kielstein JT, Hafer C.

Int J Nephrol Renovasc Dis. 2016 May 23;9:119-28. doi: 10.2147/IJNRD.S89128. eCollection 2016.


Pharmacokinetics and total removal of fosfomycin in two patients undergoing intermittent haemodialysis and extended dialysis: prescription needs to avoid under-dosing.

Schmidt JJ, Bode-Böger SM, Wilhelmi M, Omar M, Martens-Lobenhoffer J, Welte T, Kielstein JT.

J Antimicrob Chemother. 2016 Sep;71(9):2673-4. doi: 10.1093/jac/dkw187. Epub 2016 Jun 5. No abstract available.


Removal of methadone by extended dialysis using a high cut-off dialyzer: implications for the treatment of overdose and for pain management in patients undergoing light chain removal.

Arelin V, Schmidt JJ, Kayser N, Kühn-Velten WN, Suhling H, Eden G, Kielstein JT.

Clin Nephrol. 2016 Jun;85(6):353-7. doi: 10.5414/CN108724.


Acute interstitial nephritis due to flecainide therapy in the 38(th) week of pregnancy.

Schmidt JJ, Ramazan L, Bockemeyer C, Günter HH, Martens-Lobenhoffer J, Ganzenmüller T, Bode-Böger SM, Kielstein JT.

BMC Nephrol. 2016 Mar 15;17:28. doi: 10.1186/s12882-016-0240-8.


Neurological Sequelae in Adults After E coli O104: H4 Infection-Induced Hemolytic-Uremic Syndrome.

Schuppner R, Maehlmann J, Dirks M, Worthmann H, Tryc AB, Sandorski K, Bahlmann E, Kielstein JT, Giesemann AM, Lanfermann H, Weissenborn K.

Medicine (Baltimore). 2016 Feb;95(6):e2337. doi: 10.1097/MD.0000000000002337.


Involvement of Angiopoietin-2 and Tie2 Receptor Phosphorylation in STEC-HUS Mediated by Escherichia coli O104:H4.

Lukasz A, Beneke J, Thamm K, Kielstein JT, Menne J, Mikesch JH, Schmidt BM, Haller H, Kümpers P, David S, Schiffer M.

Mediators Inflamm. 2015;2015:670248. doi: 10.1155/2015/670248. Epub 2015 Dec 24.


Ultrasound findings in EHEC-associated hemolytic-uremic syndrome and their clinical relevance.

Reising A, Hafer C, Hiss M, Kielstein JT, Menne J, Gueler F, Beneke J, Linnenweber-Held S, Haller H, Einecke G.

Int Urol Nephrol. 2016 Apr;48(4):561-70. doi: 10.1007/s11255-015-1194-7. Epub 2016 Jan 12.


Treatment of amitriptyline intoxications by extended high cut-off dialysis.

Schmidt JJ, Bertram A, Kühn-Velten WN, Suhling H, Wiesner O, Schneider A, Kielstein JT.

Clin Kidney J. 2015 Dec;8(6):796-9. doi: 10.1093/ckj/sfv094. Epub 2015 Sep 29.


Prolonged Mechanical Ventilation After Lung Transplantation-A Single-Center Study.

Hadem J, Gottlieb J, Seifert D, Fegbeutel C, Sommer W, Greer M, Wiesner O, Kielstein JT, Schneider AS, Ius F, Fuge J, Kühn C, Tudorache I, Haverich A, Welte T, Warnecke G, Hoeper MM.

Am J Transplant. 2016 May;16(5):1579-87. doi: 10.1111/ajt.13632. Epub 2016 Feb 26.


[Plasma exchange in treatment refractory septic shock : Presentation of a therapeutic add-on strategy].

David S, Hoeper MM, Kielstein JT.

Med Klin Intensivmed Notfmed. 2017 Feb;112(1):42-46. doi: 10.1007/s00063-015-0117-9. Epub 2015 Nov 24. German.


Membrane versus centrifuge-based therapeutic plasma exchange: a randomized prospective crossover study.

Hafer C, Golla P, Gericke M, Eden G, Beutel G, Schmidt JJ, Schmidt BM, De Reys S, Kielstein JT.

Int Urol Nephrol. 2016 Jan;48(1):133-8. doi: 10.1007/s11255-015-1137-3. Epub 2015 Nov 3.


Single- and multiple-dose pharmacokinetics of ethambutol and rifampicin in a tuberculosis patient with acute respiratory distress syndrome undergoing extended daily dialysis and ECMO treatment.

Strunk AK, Ciesek S, Schmidt JJ, Kühn C, Hoeper MM, Welte T, Kielstein JT.

Int J Infect Dis. 2016 Jan;42:1-3. doi: 10.1016/j.ijid.2015.10.018. Epub 2015 Oct 27.


Ceftolozane-tazobactam versus levofloxacin in urinary tract infection.

Kielstein JT, Schmidt JJ.

Lancet. 2015 Sep 26;386(10000):1241. doi: 10.1016/S0140-6736(15)00261-5. No abstract available.


Effect of therapeutic plasma exchange on plasma levels and total removal of adipokines and inflammatory markers.

Schmidt JJ, Jahn J, Golla P, Hafer C, Kielstein JT, Kielstein H.

BMC Obes. 2015 Sep 30;2:37. doi: 10.1186/s40608-015-0067-z. eCollection 2015.


Cognitive Function in Patients With Chronic Kidney Disease: Challenges in Neuropsychological Assessments.

Schneider SM, Kielstein JT, Braverman J, Novak M.

Semin Nephrol. 2015 Jul;35(4):304-10. doi: 10.1016/j.semnephrol.2015.06.002. Review.


Role of the endogenous nitric oxide inhibitor asymmetric dimethylarginine (ADMA) and brain-derived neurotrophic factor (BDNF) in depression and behavioural changes: clinical and preclinical data in chronic kidney disease.

Kielstein H, Suntharalingam M, Perthel R, Song R, Schneider SM, Martens-Lobenhoffer J, Jäger K, Bode-Böger SM, Kielstein JT.

Nephrol Dial Transplant. 2015 Oct;30(10):1699-705. doi: 10.1093/ndt/gfv253. Epub 2015 Jul 13.


[After the crisis is before the crisis: Coping-strategies for public health emergency situations on different levels--experiences of the German E. coli outbreak 2011].

Auschra C, Kielstein JT, Tecklenburg A, Müller-Seitz G.

MMW Fortschr Med. 2014 Dec 15;156 Suppl 4:115-9. German.


Serum uric acid and the risk of cardiovascular and renal disease.

Borghi C, Rosei EA, Bardin T, Dawson J, Dominiczak A, Kielstein JT, Manolis AJ, Perez-Ruiz F, Mancia G.

J Hypertens. 2015 Sep;33(9):1729-41; discussion 1741. doi: 10.1097/HJH.0000000000000701. Review.


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