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Items: 17


Patterns of expression of factor VIII and von Willebrand factor by endothelial cell subsets in vivo.

Pan J, Dinh TT, Rajaraman A, Lee M, Scholz A, Czupalla CJ, Kiefel H, Zhu L, Xia L, Morser J, Jiang H, Santambrogio L, Butcher EC.

Blood. 2016 Jul 7;128(1):104-9. doi: 10.1182/blood-2015-12-684688. Epub 2016 May 12.


Angiogenic cytokines are antibody targets during graft-versus-leukemia reactions.

Piesche M, Ho VT, Kim H, Nakazaki Y, Nehil M, Yaghi NK, Kolodin D, Weiser J, Altevogt P, Kiefel H, Alyea EP, Antin JH, Cutler C, Koreth J, Canning C, Ritz J, Soiffer RJ, Dranoff G.

Clin Cancer Res. 2015 Mar 1;21(5):1010-8. doi: 10.1158/1078-0432.CCR-14-1956. Epub 2014 Dec 23.


Transcriptional programs of lymphoid tissue capillary and high endothelium reveal control mechanisms for lymphocyte homing.

Lee M, Kiefel H, LaJevic MD, Macauley MS, Kawashima H, O'Hara E, Pan J, Paulson JC, Butcher EC.

Nat Immunol. 2014 Oct;15(10):982-95. doi: 10.1038/ni.2983. Epub 2014 Aug 31. Erratum in: Nat Immunol. 2015 Feb;16(2):214. Kawashima, Hiroto [added].


Role of miR-34a as a suppressor of L1CAM in endometrial carcinoma.

Schirmer U, Doberstein K, Rupp AK, Bretz NP, Wuttig D, Kiefel H, Breunig C, Fiegl H, Müller-Holzner E, Zeillinger R, Schuster E, Zeimet AG, Sültmann H, Altevogt P.

Oncotarget. 2014 Jan 30;5(2):462-72.


L1CAM: a major driver for tumor cell invasion and motility.

Kiefel H, Bondong S, Hazin J, Ridinger J, Schirmer U, Riedle S, Altevogt P.

Cell Adh Migr. 2012 Jul-Aug;6(4):374-84. doi: 10.4161/cam.20832. Epub 2012 Jul 1. Review.


EMT-associated up-regulation of L1CAM provides insights into L1CAM-mediated integrin signalling and NF-κB activation.

Kiefel H, Bondong S, Pfeifer M, Schirmer U, Erbe-Hoffmann N, Schäfer H, Sebens S, Altevogt P.

Carcinogenesis. 2012 Oct;33(10):1919-29. doi: 10.1093/carcin/bgs220. Epub 2012 Jul 4.


Prognostic significance of L1CAM in ovarian cancer and its role in constitutive NF-κB activation.

Bondong S, Kiefel H, Hielscher T, Zeimet AG, Zeillinger R, Pils D, Schuster E, Castillo-Tong DC, Cadron I, Vergote I, Braicu I, Sehouli J, Mahner S, Fogel M, Altevogt P.

Ann Oncol. 2012 Jul;23(7):1795-802. doi: 10.1093/annonc/mdr568. Epub 2012 Jan 6.


Combined treatment of L1CAM antibodies and cytostatic drugs improve the therapeutic response of pancreatic and ovarian carcinoma.

Schäfer H, Dieckmann C, Korniienko O, Moldenhauer G, Kiefel H, Salnikov A, Krüger A, Altevogt P, Sebens S.

Cancer Lett. 2012 Jun 1;319(1):66-82. doi: 10.1016/j.canlet.2011.12.035. Epub 2011 Dec 27.


Myofibroblast-induced tumorigenicity of pancreatic ductal epithelial cells is L1CAM dependent.

Schäfer H, Geismann C, Heneweer C, Egberts JH, Korniienko O, Kiefel H, Moldenhauer G, Bachem MG, Kalthoff H, Altevogt P, Sebens S.

Carcinogenesis. 2012 Jan;33(1):84-93. doi: 10.1093/carcin/bgr262. Epub 2011 Nov 17.


Regulation of transcription factor E2F3a and its clinical relevance in ovarian cancer.

Reimer D, Hubalek M, Kiefel H, Riedle S, Skvortsov S, Erdel M, Hofstetter G, Concin N, Fiegl H, Müller-Holzner E, Marth C, Altevogt P, Zeimet AG.

Oncogene. 2011 Sep 22;30(38):4038-49. doi: 10.1038/onc.2011.119. Epub 2011 Apr 25.


Linking L1CAM-mediated signaling to NF-κB activation.

Kiefel H, Pfeifer M, Bondong S, Hazin J, Altevogt P.

Trends Mol Med. 2011 Apr;17(4):178-87. doi: 10.1016/j.molmed.2010.11.005. Epub 2010 Dec 30. Review.


L1CAM-integrin interaction induces constitutive NF-kappaB activation in pancreatic adenocarcinoma cells by enhancing IL-1beta expression.

Kiefel H, Bondong S, Erbe-Hoffmann N, Hazin J, Riedle S, Wolf J, Pfeifer M, Arlt A, Schäfer H, Müerköster SS, Altevogt P.

Oncogene. 2010 Aug 26;29(34):4766-78. doi: 10.1038/onc.2010.230. Epub 2010 Jun 14.


Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma.

Wolterink S, Moldenhauer G, Fogel M, Kiefel H, Pfeifer M, Lüttgau S, Gouveia R, Costa J, Endell J, Moebius U, Altevogt P.

Cancer Res. 2010 Mar 15;70(6):2504-15. doi: 10.1158/0008-5472.CAN-09-3730. Epub 2010 Mar 9.


Up-regulation of L1CAM is linked to loss of hormone receptors and E-cadherin in aggressive subtypes of endometrial carcinomas.

Huszar M, Pfeifer M, Schirmer U, Kiefel H, Konecny GE, Ben-Arie A, Edler L, Münch M, Müller-Holzner E, Jerabek-Klestil S, Abdel-Azim S, Marth C, Zeimet AG, Altevogt P, Fogel M.

J Pathol. 2010 Apr;220(5):551-61. doi: 10.1002/path.2673.


Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/gamma-secretase activity.

Riedle S, Kiefel H, Gast D, Bondong S, Wolterink S, Gutwein P, Altevogt P.

Biochem J. 2009 May 27;420(3):391-402. doi: 10.1042/BJ20081625.


The RGD integrin binding site in human L1-CAM is important for nuclear signaling.

Gast D, Riedle S, Kiefel H, Müerköster SS, Schäfer H, Schäfer MK, Altevogt P.

Exp Cell Res. 2008 Aug 1;314(13):2411-8. doi: 10.1016/j.yexcr.2008.04.004. Epub 2008 Apr 12.


L1 cell adhesion molecule (L1CAM) as a pathogenetic factor in endometriosis.

Finas D, Huszar M, Agic A, Dogan S, Kiefel H, Riedle S, Gast D, Marcovich R, Noack F, Altevogt P, Fogel M, Hornung D.

Hum Reprod. 2008 May;23(5):1053-62. doi: 10.1093/humrep/den044. Epub 2008 Mar 10.


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