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Items: 20

1.

Plasma Protein Biomarkers for the Prediction of CSF Amyloid and Tau and [18F]-Flutemetamol PET Scan Result.

Westwood S, Baird AL, Hye A, Ashton NJ, Nevado-Holgado AJ, Anand SN, Liu B, Newby D, Bazenet C, Kiddle SJ, Ward M, Newton B, Desai K, Tan Hehir C, Zanette M, Galimberti D, Parnetti L, Lleó A, Baker S, Narayan VA, van der Flier WM, Scheltens P, Teunissen CE, Visser PJ, Lovestone S.

Front Aging Neurosci. 2018 Dec 11;10:409. doi: 10.3389/fnagi.2018.00409. eCollection 2018.

2.

Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.

Jansen IE, Savage JE, Watanabe K, Bryois J, Williams DM, Steinberg S, Sealock J, Karlsson IK, Hägg S, Athanasiu L, Voyle N, Proitsi P, Witoelar A, Stringer S, Aarsland D, Almdahl IS, Andersen F, Bergh S, Bettella F, Bjornsson S, Brækhus A, Bråthen G, de Leeuw C, Desikan RS, Djurovic S, Dumitrescu L, Fladby T, Hohman TJ, Jonsson PV, Kiddle SJ, Rongve A, Saltvedt I, Sando SB, Selbæk G, Shoai M, Skene NG, Snaedal J, Stordal E, Ulstein ID, Wang Y, White LR, Hardy J, Hjerling-Leffler J, Sullivan PF, van der Flier WM, Dobson R, Davis LK, Stefansson H, Stefansson K, Pedersen NL, Ripke S, Andreassen OA, Posthuma D.

Nat Genet. 2019 Jan 7. doi: 10.1038/s41588-018-0311-9. [Epub ahead of print]

PMID:
30617256
3.

Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic.

Hampel H, O'Bryant SE, Molinuevo JL, Zetterberg H, Masters CL, Lista S, Kiddle SJ, Batrla R, Blennow K.

Nat Rev Neurol. 2018 Nov;14(11):639-652. doi: 10.1038/s41582-018-0079-7. Review.

PMID:
30297701
4.

A Blood Test for Alzheimer's Disease: Progress, Challenges, and Recommendations.

Kiddle SJ, Voyle N, Dobson RJB.

J Alzheimers Dis. 2018;64(s1):S289-S297. doi: 10.3233/JAD-179904.

5.

Genetic Risk as a Marker of Amyloid-β and Tau Burden in Cerebrospinal Fluid.

Voyle N, Patel H, Folarin A, Newhouse S, Johnston C, Visser PJ, Dobson RJ, Kiddle SJ; EDAR and DESCRIPA study groups and the Alzheimer’s Disease Neuroimaging Initiative.

J Alzheimers Dis. 2017;55(4):1417-1427. doi: 10.3233/JAD-160707.

6.

Alzheimer's disease: are blood and brain markers related? A systematic review.

Khan AT, Dobson RJ, Sattlecker M, Kiddle SJ.

Ann Clin Transl Neurol. 2016 May 11;3(6):455-62. doi: 10.1002/acn3.313. eCollection 2016 Jun.

7.

Blood-Based Biomarker Candidates of Cerebral Amyloid Using PiB PET in Non-Demented Elderly.

Westwood S, Leoni E, Hye A, Lynham S, Khondoker MR, Ashton NJ, Kiddle SJ, Baird AL, Sainz-Fuertes R, Leung R, Graf J, Hehir CT, Baker D, Cereda C, Bazenet C, Ward M, Thambisetty M, Lovestone S.

J Alzheimers Dis. 2016 Mar 29;52(2):561-72. doi: 10.3233/JAD-151155.

8.

Blood metabolite markers of neocortical amyloid-β burden: discovery and enrichment using candidate proteins.

Voyle N, Kim M, Proitsi P, Ashton NJ, Baird AL, Bazenet C, Hye A, Westwood S, Chung R, Ward M, Rabinovici GD, Lovestone S, Breen G, Legido-Quigley C, Dobson RJ, Kiddle SJ; Alzheimer's Disease Neuroimaging Initiative.

Transl Psychiatry. 2016 Jan 26;6:e719. doi: 10.1038/tp.2015.205.

9.

No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer's Disease.

Chiam JT, Lunnon K, Voyle N, Proitsi P, Coppola G, Geschwind D, Nelson S, Johnston C, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Hodges A, Lovestone S, Newhouse S, Dobson RJ, Kiddle SJ, Sattlecker M.

J Alzheimers Dis. 2015;47(3):741-50. doi: 10.3233/JAD-150289.

PMID:
26401708
10.

A Subset of Cerebrospinal Fluid Proteins from a Multi-Analyte Panel Associated with Brain Atrophy, Disease Classification and Prediction in Alzheimer's Disease.

Khan W, Aguilar C, Kiddle SJ, Doyle O, Thambisetty M, Muehlboeck S, Sattlecker M, Newhouse S, Lovestone S, Dobson R, Giampietro V, Westman E, Simmons A; Alzheimer’s Disease Neuroimaging Initiative.

PLoS One. 2015 Aug 18;10(8):e0134368. doi: 10.1371/journal.pone.0134368. eCollection 2015.

11.

Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes.

Kiddle SJ, Steves CJ, Mehta M, Simmons A, Xu X, Newhouse S, Sattlecker M, Ashton NJ, Bazenet C, Killick R, Adnan J, Westman E, Nelson S, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Curtis C, Breen G, Williams SC, Lovestone S, Spector TD, Dobson RJ.

Transl Psychiatry. 2015 Jun 16;5:e584. doi: 10.1038/tp.2015.78.

12.

Blood protein predictors of brain amyloid for enrichment in clinical trials?

Ashton NJ, Kiddle SJ, Graf J, Ward M, Baird AL, Hye A, Westwood S, Wong KV, Dobson RJ, Rabinovici GD, Miller BL, Rosen HJ, Torres A, Zhang Z, Thurfjell L, Covin A, Hehir CT, Baker D, Bazenet C, Lovestone S; AIBL Research Group.

Alzheimers Dement (Amst). 2015 Mar 29;1(1):48-60. doi: 10.1016/j.dadm.2014.11.005. eCollection 2015 Mar.

13.

Circulating Proteomic Signatures of Chronological Age.

Menni C, Kiddle SJ, Mangino M, Viñuela A, Psatha M, Steves C, Sattlecker M, Buil A, Newhouse S, Nelson S, Williams S, Voyle N, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Spector TD, Dobson R, Valdes AM.

J Gerontol A Biol Sci Med Sci. 2015 Jul;70(7):809-16. doi: 10.1093/gerona/glu121. Epub 2014 Aug 14.

14.

Are blood-based protein biomarkers for Alzheimer's disease also involved in other brain disorders? A systematic review.

Chiam JT, Dobson RJ, Kiddle SJ, Sattlecker M.

J Alzheimers Dis. 2015;43(1):303-14. doi: 10.3233/JAD-140816. Review.

PMID:
25096613
15.

Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology.

Sattlecker M, Kiddle SJ, Newhouse S, Proitsi P, Nelson S, Williams S, Johnston C, Killick R, Simmons A, Westman E, Hodges A, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S; AddNeuroMed Consortium, Dobson RJ.

Alzheimers Dement. 2014 Nov;10(6):724-34. doi: 10.1016/j.jalz.2013.09.016. Epub 2014 Apr 25.

16.

Wigwams: identifying gene modules co-regulated across multiple biological conditions.

Polanski K, Rhodes J, Hill C, Zhang P, Jenkins DJ, Kiddle SJ, Jironkin A, Beynon J, Buchanan-Wollaston V, Ott S, Denby KJ.

Bioinformatics. 2014 Apr 1;30(7):962-70. doi: 10.1093/bioinformatics/btt728. Epub 2013 Dec 18.

17.

Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study.

Kiddle SJ, Sattlecker M, Proitsi P, Simmons A, Westman E, Bazenet C, Nelson SK, Williams S, Hodges A, Johnston C, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Newhouse S, Lovestone S, Dobson RJ.

J Alzheimers Dis. 2014;38(3):515-31. doi: 10.3233/JAD-130380. Review.

PMID:
24121966
18.

Plasma based markers of [11C] PiB-PET brain amyloid burden.

Kiddle SJ, Thambisetty M, Simmons A, Riddoch-Contreras J, Hye A, Westman E, Pike I, Ward M, Johnston C, Lupton MK, Lunnon K, Soininen H, Kloszewska I, Tsolaki M, Vellas B, Mecocci P, Lovestone S, Newhouse S, Dobson R; Alzheimers Disease Neuroimaging Initiative.

PLoS One. 2012;7(9):e44260. doi: 10.1371/journal.pone.0044260. Epub 2012 Sep 24.

19.

Arabidopsis defense against Botrytis cinerea: chronology and regulation deciphered by high-resolution temporal transcriptomic analysis.

Windram O, Madhou P, McHattie S, Hill C, Hickman R, Cooke E, Jenkins DJ, Penfold CA, Baxter L, Breeze E, Kiddle SJ, Rhodes J, Atwell S, Kliebenstein DJ, Kim YS, Stegle O, Borgwardt K, Zhang C, Tabrett A, Legaie R, Moore J, Finkenstadt B, Wild DL, Mead A, Rand D, Beynon J, Ott S, Buchanan-Wollaston V, Denby KJ.

Plant Cell. 2012 Sep;24(9):3530-57. doi: 10.1105/tpc.112.102046. Epub 2012 Sep 28.

20.

Temporal clustering by affinity propagation reveals transcriptional modules in Arabidopsis thaliana.

Kiddle SJ, Windram OP, McHattie S, Mead A, Beynon J, Buchanan-Wollaston V, Denby KJ, Mukherjee S.

Bioinformatics. 2010 Feb 1;26(3):355-62. doi: 10.1093/bioinformatics/btp673. Epub 2009 Dec 8.

PMID:
19996165

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