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Items: 19

1.

Mixed-model association for biobank-scale datasets.

Loh PR, Kichaev G, Gazal S, Schoech AP, Price AL.

Nat Genet. 2018 Jun 11. doi: 10.1038/s41588-018-0144-6. [Epub ahead of print] No abstract available.

PMID:
29892013
2.

Methods for fine-mapping with chromatin and expression data.

Roytman M, Kichaev G, Gusev A, Pasaniuc B.

PLoS Genet. 2018 Feb 26;14(2):e1007240. doi: 10.1371/journal.pgen.1007240. eCollection 2018 Feb.

3.

Widespread Allelic Heterogeneity in Complex Traits.

Hormozdiari F, Zhu A, Kichaev G, Ju CJ, Segrè AV, Joo JWJ, Won H, Sankararaman S, Pasaniuc B, Shifman S, Eskin E.

Am J Hum Genet. 2017 May 4;100(5):789-802. doi: 10.1016/j.ajhg.2017.04.005.

4.

Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci.

Zubair N, Graff M, Luis Ambite J, Bush WS, Kichaev G, Lu Y, Manichaikul A, Sheu WH, Absher D, Assimes TL, Bielinski SJ, Bottinger EP, Buzkova P, Chuang LM, Chung RH, Cochran B, Dumitrescu L, Gottesman O, Haessler JW, Haiman C, Heiss G, Hsiung CA, Hung YJ, Hwu CM, Juang JJ, Le Marchand L, Lee IT, Lee WJ, Lin LA, Lin D, Lin SY, Mackey RH, Martin LW, Pasaniuc B, Peters U, Predazzi I, Quertermous T, Reiner AP, Robinson J, Rotter JI, Ryckman KK, Schreiner PJ, Stahl E, Tao R, Tsai MY, Waite LL, Wang TD, Buyske S, Ida Chen YD, Cheng I, Crawford DC, Loos RJF, Rich SS, Fornage M, North KE, Kooperberg C, Carty CL.

Hum Mol Genet. 2016 Dec 15;25(24):5500-5512. doi: 10.1093/hmg/ddw358.

5.

Enhanced methods to detect haplotypic effects on gene expression.

Brown R, Kichaev G, Mancuso N, Boocock J, Pasaniuc B.

Bioinformatics. 2017 Aug 1;33(15):2307-2313. doi: 10.1093/bioinformatics/btx142.

PMID:
28369161
6.

Integrating Gene Expression with Summary Association Statistics to Identify Genes Associated with 30 Complex Traits.

Mancuso N, Shi H, Goddard P, Kichaev G, Gusev A, Pasaniuc B.

Am J Hum Genet. 2017 Mar 2;100(3):473-487. doi: 10.1016/j.ajhg.2017.01.031. Epub 2017 Feb 23.

7.

Improved methods for multi-trait fine mapping of pleiotropic risk loci.

Kichaev G, Roytman M, Johnson R, Eskin E, Lindström S, Kraft P, Pasaniuc B.

Bioinformatics. 2017 Jan 15;33(2):248-255. doi: 10.1093/bioinformatics/btw615. Epub 2016 Sep 22.

8.

Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data.

Shi H, Kichaev G, Pasaniuc B.

Am J Hum Genet. 2016 Jul 7;99(1):139-53. doi: 10.1016/j.ajhg.2016.05.013. Epub 2016 Jun 23.

9.

Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation.

Gusev A, Shi H, Kichaev G, Pomerantz M, Li F, Long HW, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Zheng W, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJ, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Witte JS, Casey G, Kaggwa S, Cook MB, Stram DO, Blot WJ, Eeles RA, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Southey MC, Fitzgerald LM, Gronberg H, Wiklund F, Aly M, Henderson BE, Schleutker J, Wahlfors T, Tammela TL, Nordestgaard BG, Key TJ, Travis RC, Neal DE, Donovan JL, Hamdy FC, Pharoah P, Pashayan N, Khaw KT, Stanford JL, Thibodeau SN, McDonnell SK, Schaid DJ, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Wokolorczyk D, Kluzniak W, Cannon-Albright L, Teerlink C, Brenner H, Dieffenbach AK, Arndt V, Park JY, Sellers TA, Lin HY, Slavov C, Kaneva R, Mitev V, Batra J, Spurdle A, Clements JA, Teixeira MR, Pandha H, Michael A, Paulo P, Maia S, Kierzek A; PRACTICAL consortium, Conti DV, Albanes D, Berg C, Berndt SI, Campa D, Crawford ED, Diver WR, Gapstur SM, Gaziano JM, Giovannucci E, Hoover R, Hunter DJ, Johansson M, Kraft P, Le Marchand L, Lindström S, Navarro C, Overvad K, Riboli E, Siddiq A, Stevens VL, Trichopoulos D, Vineis P, Yeager M, Trynka G, Raychaudhuri S, Schumacher FR, Price AL, Freedman ML, Haiman CA, Pasaniuc B.

Nat Commun. 2016 Apr 7;7:10979. doi: 10.1038/ncomms10979.

10.

Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies.

Kichaev G, Pasaniuc B.

Am J Hum Genet. 2015 Aug 6;97(2):260-71. doi: 10.1016/j.ajhg.2015.06.007. Epub 2015 Jul 16. Erratum in: Am J Hum Genet. 2015 Aug 6;97(2):353.

11.

Identification of causal genes for complex traits.

Hormozdiari F, Kichaev G, Yang WY, Pasaniuc B, Eskin E.

Bioinformatics. 2015 Jun 15;31(12):i206-13. doi: 10.1093/bioinformatics/btv240.

12.

Leveraging ancestry to improve causal variant identification in exome sequencing for monogenic disorders.

Brown R, Lee H, Eskin A, Kichaev G, Lohmueller KE, Reversade B, Nelson SF, Pasaniuc B.

Eur J Hum Genet. 2016 Jan;24(1):113-9. doi: 10.1038/ejhg.2015.68. Epub 2015 Apr 22.

13.

Integrating functional data to prioritize causal variants in statistical fine-mapping studies.

Kichaev G, Yang WY, Lindstrom S, Hormozdiari F, Eskin E, Price AL, Kraft P, Pasaniuc B.

PLoS Genet. 2014 Oct 30;10(10):e1004722. doi: 10.1371/journal.pgen.1004722. eCollection 2014 Oct.

14.

Electroporation mediated DNA vaccination directly to a mucosal surface results in improved immune responses.

Kichaev G, Mendoza JM, Amante D, Smith TR, McCoy JR, Sardesai NY, Broderick KE.

Hum Vaccin Immunother. 2013 Oct;9(10):2041-8. doi: 10.4161/hv.25272. Epub 2013 Jun 11.

15.

Optimized in vivo transfer of small interfering RNA targeting dermal tissue using in vivo surface electroporation.

Broderick KE, Chan A, Lin F, Shen X, Kichaev G, Khan AS, Aubin J, Zimmermann TS, Sardesai NY.

Mol Ther Nucleic Acids. 2012 Feb 14;1:e11. doi: 10.1038/mtna.2012.1.

16.

Elucidating the Kinetics of Expression and Immune Cell Infiltration Resulting from Plasmid Gene Delivery Enhanced by Surface Dermal Electroporation.

Mendoza JM, Amante DH, Kichaev G, Knott CL, Kiosses WB, Smith TR, Sardesai NY, Broderick KE.

Vaccines (Basel). 2013 Aug 28;1(3):384-97. doi: 10.3390/vaccines1030384.

17.

Enhanced Delivery and Potency of Self-Amplifying mRNA Vaccines by Electroporation in Situ.

Cu Y, Broderick KE, Banerjee K, Hickman J, Otten G, Barnett S, Kichaev G, Sardesai NY, Ulmer JB, Geall A.

Vaccines (Basel). 2013 Aug 22;1(3):367-83. doi: 10.3390/vaccines1030367.

18.

Optimization of electroporation-enhanced intradermal delivery of DNA vaccine using a minimally invasive surface device.

Lin F, Shen X, Kichaev G, Mendoza JM, Yang M, Armendi P, Yan J, Kobinger GP, Bello A, Khan AS, Broderick KE, Sardesai NY.

Hum Gene Ther Methods. 2012 Jun;23(3):157-68. doi: 10.1089/hgtb.2011.209. Epub 2012 Jul 13.

19.

Weakening of negative relative to positive associations with cocaine-paired cues contributes to cue-induced responding after drug removal.

Su ZI, Kichaev G, Wenzel J, Ben-Shahar O, Ettenberg A.

Pharmacol Biochem Behav. 2012 Jan;100(3):458-63. doi: 10.1016/j.pbb.2011.10.006. Epub 2011 Oct 8.

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