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Items: 1 to 50 of 115

1.

Differential regulation of the unfolded protein response in outbred deer mice and susceptibility to metabolic disease.

Havighorst A, Zhang Y, Farmaki E, Kaza V, Chatzistamou I, Kiaris H.

Dis Model Mech. 2019 Feb 7. pii: dmm.037242. doi: 10.1242/dmm.037242. [Epub ahead of print]

2.

Support for Living Stock Collections: A Mammalian Stock Center Perspective.

Kiaris H.

Trends Genet. 2019 Mar;35(3):173-174. doi: 10.1016/j.tig.2018.12.001. Epub 2018 Dec 23.

PMID:
30587379
3.

Inhibition of tumor growth by agonists of growth hormone-releasing hormone.

Kiaris H, Chatzistamou I.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):11876-11878. doi: 10.1073/pnas.1817342115. Epub 2018 Nov 7. No abstract available.

PMID:
30404912
4.

CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases.

Liang J, Chen M, Hughes D, Chumanevich AA, Altilia S, Kaza V, Lim CU, Kiaris H, Mythreye K, Pena MM, Broude EV, Roninson IB.

Cancer Res. 2018 Dec 1;78(23):6594-6606. doi: 10.1158/0008-5472.CAN-18-1583. Epub 2018 Sep 5.

PMID:
30185549
5.

The Value of Outbred Rodent Models in Cancer Research.

Chatzistamou I, Farmaki E, Kaza V, Kiaris H.

Trends Cancer. 2018 Jul;4(7):468-471. doi: 10.1016/j.trecan.2018.05.004. Epub 2018 Jun 7.

PMID:
29937045
6.

Growth of human breast cancers in Peromyscus.

Kaza V, Farmaki E, Havighorst A, Crossland J, Chatzistamou I, Kiaris H.

Dis Model Mech. 2018 Jan 17;11(1). pii: dmm031302. doi: 10.1242/dmm.031302.

7.

Cell-autonomous cytotoxicity of type I interferon response via induction of endoplasmic reticulum stress.

Mihailidou C, Papavassiliou AG, Kiaris H.

FASEB J. 2017 Dec;31(12):5432-5439. doi: 10.1096/fj.201700152R. Epub 2017 Aug 17.

8.

The challenges faced by living stock collections in the USA.

McCluskey K, Boundy-Mills K, Dye G, Ehmke E, Gunnell GF, Kiaris H, Polihronakis Richmond M, Yoder AD, Zeigler DR, Zehr S, Grotewold E.

Elife. 2017 Mar 13;6. pii: e24611. doi: 10.7554/eLife.24611.

9.

Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer.

McDermott MS, Chumanevich AA, Lim CU, Liang J, Chen M, Altilia S, Oliver D, Rae JM, Shtutman M, Kiaris H, Győrffy B, Roninson IB, Broude EV.

Oncotarget. 2017 Feb 21;8(8):12558-12575. doi: 10.18632/oncotarget.14894.

10.

Editorial.

Kiaris H.

Semin Cell Dev Biol. 2017 Jan;61:80-81. doi: 10.1016/j.semcdb.2016.12.005. No abstract available.

PMID:
28081800
11.

Induction of the MCP chemokine cluster cascade in the periphery by cancer cell-derived Ccl3.

Farmaki E, Kaza V, Papavassiliou AG, Chatzistamou I, Kiaris H.

Cancer Lett. 2017 Mar 28;389:49-58. doi: 10.1016/j.canlet.2016.12.028. Epub 2016 Dec 29.

12.

Modulation of Pancreatic Islets' Function and Survival During Aging Involves the Differential Regulation of Endoplasmic Reticulum Stress by p21 and CHOP.

Mihailidou C, Chatzistamou I, Papavassiliou AG, Kiaris H.

Antioxid Redox Signal. 2017 Aug 1;27(4):185-200. doi: 10.1089/ars.2016.6671. Epub 2017 Jan 16.

13.

Ciclopirox enhances pancreatic islet health by modulating the unfolded protein response in diabetes.

Mihailidou C, Chatzistamou I, Papavassiliou AG, Kiaris H.

Pflugers Arch. 2016 Nov;468(11-12):1957-1968. Epub 2016 Oct 19.

14.

Modeling estrogen receptor-positive breast cancers in mice: is it the best we can do?

Chatzistamou I, Kiaris H.

Endocr Relat Cancer. 2016 Nov;23(11):C9-C12. Epub 2016 Sep 12.

15.

Crosstalk between C/EBP homologous protein (CHOP) and glucocorticoid receptor in lung cancer.

Mihailidou C, Panagiotou C, Kiaris H, Kassi E, Moutsatsou P.

Mol Cell Endocrinol. 2016 Nov 15;436:211-23. doi: 10.1016/j.mce.2016.08.001. Epub 2016 Aug 3.

PMID:
27496643
16.

Peromyscus as a model of human disease.

Havighorst A, Crossland J, Kiaris H.

Semin Cell Dev Biol. 2017 Jan;61:150-155. doi: 10.1016/j.semcdb.2016.06.020. Epub 2016 Jun 29. Review.

PMID:
27375227
17.

Systemic effects of AGEs in ER stress induction in vivo.

Adamopoulos C, Mihailidou C, Grivaki C, Papavassiliou KA, Kiaris H, Piperi C, Papavassiliou AG.

Glycoconj J. 2016 Aug;33(4):537-44. doi: 10.1007/s10719-016-9680-4. Epub 2016 May 28. Review.

PMID:
27236787
18.

A CCL8 gradient drives breast cancer cell dissemination.

Farmaki E, Chatzistamou I, Kaza V, Kiaris H.

Oncogene. 2016 Dec 8;35(49):6309-6318. doi: 10.1038/onc.2016.161. Epub 2016 May 16.

19.

Endoplasmic reticulum stress is associated with the pathogenesis of pemphigus vulgaris.

Mihailidou C, Katsoulas N, Panagiotou E, Farmaki E, Sklavounou A, Kiaris H, Chatzistamou I.

Exp Dermatol. 2016 Sep;25(9):731-3. doi: 10.1111/exd.13026. Epub 2016 Jun 15. No abstract available.

PMID:
27060358
20.

Improvement of chemotherapeutic drug efficacy by endoplasmic reticulum stress.

Mihailidou C, Chatzistamou I, Papavassiliou AG, Kiaris H.

Endocr Relat Cancer. 2015 Apr;22(2):229-38. doi: 10.1530/ERC-15-0019. Epub 2015 Feb 10.

PMID:
25670032
21.

Regulation of P21 during diabetes-associated stress of the endoplasmic reticulum.

Mihailidou C, Chatzistamou I, Papavassiliou AG, Kiaris H.

Endocr Relat Cancer. 2015 Apr;22(2):217-28. doi: 10.1530/ERC-15-0018. Epub 2015 Feb 10.

PMID:
25670031
22.

Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer.

Gargalionis AN, Korkolopoulou P, Farmaki E, Piperi C, Dalagiorgou G, Adamopoulos C, Levidou G, Saetta A, Fragkou P, Tsioli P, Kiaris H, Zizi-Serbetzoglou A, Karavokyros I, Papavassiliou KA, Tsavaris N, Patsouris E, Basdra EK, Papavassiliou AG.

Int J Cancer. 2015 Apr 1;136(7):1515-27. doi: 10.1002/ijc.29140. Epub 2014 Sep 3.

23.

A crosstalk between p21 and UPR-induced transcription factor C/EBP homologous protein (CHOP) linked to type 2 diabetes.

Mihailidou C, Papavassiliou AG, Kiaris H.

Biochimie. 2014 Apr;99:19-27. doi: 10.1016/j.biochi.2013.11.003. Epub 2013 Nov 14. Review.

PMID:
24239558
24.

Notch3 marks clonogenic mammary luminal progenitor cells in vivo.

Lafkas D, Rodilla V, Huyghe M, Mourao L, Kiaris H, Fre S.

J Cell Biol. 2013 Oct 14;203(1):47-56. doi: 10.1083/jcb.201307046. Epub 2013 Oct 7.

25.

MicroRNAs in the tumour microenvironment: big role for small players.

Soon P, Kiaris H.

Endocr Relat Cancer. 2013 Aug 23;20(5):R257-67. doi: 10.1530/ERC-13-0119. Print 2013 Oct. Review.

PMID:
23878074
26.

Selection of p53-Deficient Stromal Cells in the Tumor Microenvironment.

Farmaki E, Chatzistamou I, Bourlis P, Santoukou E, Trimis G, Papavassiliou AG, Kiaris H.

Genes Cancer. 2012 Sep;3(9-10):592-8. doi: 10.1177/1947601912474002.

27.

Advanced glycation end-products induce endoplasmic reticulum stress in human aortic endothelial cells.

Adamopoulos C, Farmaki E, Spilioti E, Kiaris H, Piperi C, Papavassiliou AG.

Clin Chem Lab Med. 2014 Jan 1;52(1):151-60. doi: 10.1515/cclm-2012-0826.

PMID:
23454718
28.

p53 antagonizes the unfolded protein response and inhibits ground glass hepatocyte development during endoplasmic reticulum stress.

Dioufa N, Chatzistamou I, Farmaki E, Papavassiliou AG, Kiaris H.

Exp Biol Med (Maywood). 2012 Oct;237(10):1173-80. doi: 10.1258/ebm.2012.012140. Epub 2012 Oct 4.

PMID:
23038705
29.

Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.

Porter DC, Farmaki E, Altilia S, Schools GP, West DK, Chen M, Chang BD, Puzyrev AT, Lim CU, Rokow-Kittell R, Friedhoff LT, Papavassiliou AG, Kalurupalle S, Hurteau G, Shi J, Baran PS, Gyorffy B, Wentland MP, Broude EV, Kiaris H, Roninson IB.

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13799-804. doi: 10.1073/pnas.1206906109. Epub 2012 Aug 6.

30.

Growth hormone-releasing hormone receptor splice variant 1 is frequently expressed in oral squamous cell carcinomas.

Dioufa N, Farmaki E, Schally AV, Kiaris H, Vlahodimitropoulos D, Papavassiliou AG, Kittas C, Block NL, Chatzistamou I.

Horm Cancer. 2012 Aug;3(4):172-80. doi: 10.1007/s12672-012-0108-8. Epub 2012 Mar 23.

PMID:
22441816
31.

Tackling transcription factors: challenges in antitumor therapy.

Grivas PD, Kiaris H, Papavassiliou AG.

Trends Mol Med. 2011 Oct;17(10):537-8. doi: 10.1016/j.molmed.2011.06.005. Epub 2011 Jul 19. No abstract available.

PMID:
21775208
32.

p21/waf1 and smooth-muscle actin α expression in stromal fibroblasts of oral cancers.

Chatzistamou I, Dioufa N, Trimis G, Sklavounou A, Kittas C, Kiaris H, Papavassiliou AG.

Cell Oncol (Dordr). 2011 Oct;34(5):483-8. doi: 10.1007/s13402-011-0044-6. Epub 2011 May 11. Erratum in: Cell Oncol (Dordr). 2011 Oct;34(5):509-10.

PMID:
21559927
33.

Growth hormone-releasing hormone: not only a neurohormone.

Kiaris H, Chatzistamou I, Papavassiliou AG, Schally AV.

Trends Endocrinol Metab. 2011 Aug;22(8):311-7. doi: 10.1016/j.tem.2011.03.006. Epub 2011 Apr 27. Review.

PMID:
21530304
34.

GHRH and wound healing.

Kiaris H, Block NL, Papavassiliou AG, Schally AV.

Commun Integr Biol. 2011 Jan;4(1):82-3. doi: 10.4161/cib.4.1.14002.

35.

ERp29 regulates response to doxorubicin by a PERK-mediated mechanism.

Farmaki E, Mkrtchian S, Papazian I, Papavassiliou AG, Kiaris H.

Biochim Biophys Acta. 2011 Jun;1813(6):1165-71. doi: 10.1016/j.bbamcr.2011.03.003. Epub 2011 Mar 22.

36.

Immunohistochemical expression of Notch signaling in the lining epithelium of periapical cysts.

Meliou E, Kerezoudis N, Tosios K, Lafkas D, Kiaris H.

J Endod. 2011 Feb;37(2):176-80. doi: 10.1016/j.joen.2010.10.007.

PMID:
21238798
37.

Notch 1 Receptor, Delta 1 Ligand and HES 1 Transcription Factor are Expressed in the Lining Epithelium of Periapical Cysts (Preliminary Study).

Meliou E, Kerezoudis N, Tosios K, Kiaris H.

Open Dent J. 2010 Jul 27;4:153-8. doi: 10.2174/1874210601004010153.

38.

Atypical induction of the unfolded protein response by mifepristone.

Dioufa N, Kassi E, Papavassiliou AG, Kiaris H.

Endocrine. 2010 Oct;38(2):167-73. doi: 10.1007/s12020-010-9362-0. Epub 2010 Jul 11.

PMID:
21046477
39.

p21/waf1 and smooth-muscle actin α expression in stromal fibroblasts of oral cancers.

Chatzistamou I, Dioufa N, Trimis G, Sklavounou A, Kittas C, Kiaris H, Papavassiliou AG.

Anal Cell Pathol (Amst). 2010;33(1):19-26. doi: 10.3233/ACP-CLO-2010-0528.

40.

Acceleration of wound healing by growth hormone-releasing hormone and its agonists.

Dioufa N, Schally AV, Chatzistamou I, Moustou E, Block NL, Owens GK, Papavassiliou AG, Kiaris H.

Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18611-5. doi: 10.1073/pnas.1013942107. Epub 2010 Oct 11.

41.

Evaluation of Re and (99m)Tc complexes of 2-(4'-aminophenyl)benzothiazole as potential breast cancer radiopharmaceuticals.

Tzanopoulou S, Sagnou M, Paravatou-Petsotas M, Gourni E, Loudos G, Xanthopoulos S, Lafkas D, Kiaris H, Varvarigou A, Pirmettis IC, Papadopoulos M, Pelecanou M.

J Med Chem. 2010 Jun 24;53(12):4633-41. doi: 10.1021/jm1001293.

PMID:
20518489
42.

CHOP-dependent regulation of p21/waf1 during ER stress.

Mihailidou C, Papazian I, Papavassiliou AG, Kiaris H.

Cell Physiol Biochem. 2010;25(6):761-6. doi: 10.1159/000315096. Epub 2010 May 18.

43.

Editorial.

Kiaris H.

Semin Cell Dev Biol. 2010 Feb;21(1):1. doi: 10.1016/j.semcdb.2009.11.020. Epub 2009 Dec 3. No abstract available.

PMID:
19962445
44.

Regulation of tumor-stromal fibroblast interactions: implications in anticancer therapy.

Kiaris H, Trimis G, Papavassiliou AG.

Curr Med Chem. 2008;15(29):3062-7. Review.

PMID:
19075653
45.

Essential role of p21/waf1 in the mediation of the anti-proliferative effects of GHRH antagonist JMR-132.

Volakaki AA, Lafkas D, Kassi E, Schally AV, Papavassiliou AG, Kiaris H.

J Mol Endocrinol. 2008 Nov;41(5):389-92. doi: 10.1677/JME-08-0106. Epub 2008 Sep 2.

PMID:
18765563
46.

Expression of p21waf1/Cip1 in stromal fibroblasts of primary breast tumors.

Trimis G, Chatzistamou I, Politi K, Kiaris H, Papavassiliou AG.

Hum Mol Genet. 2008 Nov 15;17(22):3596-600. doi: 10.1093/hmg/ddn252. Epub 2008 Aug 18.

PMID:
18713757
47.

Fibroblast independency in tumors: implications in cancer therapy.

Tsellou E, Kiaris H.

Future Oncol. 2008 Jun;4(3):427-32. doi: 10.2217/14796694.4.3.427. Review.

PMID:
18518767
48.

P53 mutations in stromal fibroblasts sensitize tumors against chemotherapy.

Lafkas D, Trimis G, Papavassiliou AG, Kiaris H.

Int J Cancer. 2008 Aug 15;123(4):967-71. doi: 10.1002/ijc.23546.

49.

Prognostic value of computer-assisted morphological and morphometrical analysis for detecting the recurrence tendency of basal cell carcinoma.

Cheretis C, Angelidou E, Dietrich F, Politi E, Kiaris H, Koutselini H.

Med Sci Monit. 2008 May;14(5):MT13-19.

PMID:
18443558
50.

ERp29, an endoplasmic reticulum secretion factor is involved in the growth of breast tumor xenografts.

Mkrtchian S, Baryshev M, Sargsyan E, Chatzistamou I, Volakaki AA, Chaviaras N, Pafiti A, Triantafyllou A, Kiaris H.

Mol Carcinog. 2008 Nov;47(11):886-92. doi: 10.1002/mc.20444.

PMID:
18395818

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