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The HDAC3 enzymatic activity regulates skeletal muscle fuel metabolism.

Song S, Wen Y, Tong H, Loro E, Gong Y, Liu J, Hong S, Li L, Khurana TS, Chu M, Sun Z.

J Mol Cell Biol. 2019 Feb 1;11(2):133-143. doi: 10.1093/jmcb/mjy066.


Elongated mitochondrial constrictions and fission in muscle fatigue.

Lavorato M, Loro E, Debattisti V, Khurana TS, Franzini-Armstrong C.

J Cell Sci. 2018 Dec 5;131(23). pii: jcs221028. doi: 10.1242/jcs.221028.


Mitochondrial ultrastructural adaptations in fast muscles of mice lacking IL15RA.

Loro E, Bisetto S, Khurana TS.

J Cell Sci. 2018 Nov 2;131(21). pii: jcs218313. doi: 10.1242/jcs.218313.


ZD7288 and mibefradil inhibit the myogenic heartbeat in Daphnia magna indicating its dependency on HCN and T-type calcium ion channels.

Pirtle TJ, Carr TL, Khurana T, Meeker G.

Comp Biochem Physiol A Mol Integr Physiol. 2018 Aug;222:36-42. doi: 10.1016/j.cbpa.2018.04.009. Epub 2018 Apr 21.


Functional improvement of dystrophic muscle by repression of utrophin: let-7c interaction.

Mishra MK, Loro E, Sengupta K, Wilton SD, Khurana TS.

PLoS One. 2017 Oct 18;12(10):e0182676. doi: 10.1371/journal.pone.0182676. eCollection 2017.


Cross-reaction between Formosan termite (Coptotermes formosanus) proteins and cockroach allergens.

Mattison CP, Khurana T, Tarver MR, Florane CB, Grimm CC, Pakala SB, Cottone CB, Riegel C, Bren-Mattison Y, Slater JE.

PLoS One. 2017 Aug 2;12(8):e0182260. doi: 10.1371/journal.pone.0182260. eCollection 2017.


In Vivo Evaluation of the Mechanical and Viscoelastic Properties of the Rat Tongue.

Loro E, Wang SH, Schwab RJ, Khurana TS.

J Vis Exp. 2017 Jul 6;(125). doi: 10.3791/56006.


IL15RA is required for osteoblast function and bone mineralization.

Loro E, Ramaswamy G, Chandra A, Tseng WJ, Mishra MK, Shore EM, Khurana TS.

Bone. 2017 Oct;103:20-30. doi: 10.1016/j.bone.2017.06.003. Epub 2017 Jun 6.


Allergenic extracts to diagnose and treat sensitivity to insect venoms and inhaled allergens.

Khurana T, Bridgewater JL, Rabin RL.

Ann Allergy Asthma Immunol. 2017 May;118(5):531-536. doi: 10.1016/j.anai.2016.05.026. Review.


DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress.

Simonson B, Subramanya V, Chan MC, Zhang A, Franchino H, Ottaviano F, Mishra MK, Knight AC, Hunt D, Ghiran I, Khurana TS, Kontaridis MI, Rosenzweig A, Das S.

Sci Signal. 2017 Feb 28;10(468). pii: eaaf5967. doi: 10.1126/scisignal.aaf5967.


Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion.

Hong S, Zhou W, Fang B, Lu W, Loro E, Damle M, Ding G, Jager J, Zhang S, Zhang Y, Feng D, Chu Q, Dill BD, Molina H, Khurana TS, Rabinowitz JD, Lazar MA, Sun Z.

Nat Med. 2017 Feb;23(2):223-234. doi: 10.1038/nm.4245. Epub 2016 Dec 19.


Development of Experimental Myopia in Chicks in a Natural Environment.

Stone RA, Cohen Y, McGlinn AM, Davison S, Casavant S, Shaffer J, Khurana TS, Pardue MT, Iuvone PM.

Invest Ophthalmol Vis Sci. 2016 Sep 1;57(11):4779-89. doi: 10.1167/iovs.16-19310.


Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle.

Frederick DW, Loro E, Liu L, Davila A Jr, Chellappa K, Silverman IM, Quinn WJ 3rd, Gosai SJ, Tichy ED, Davis JG, Mourkioti F, Gregory BD, Dellinger RW, Redpath P, Migaud ME, Nakamaru-Ogiso E, Rabinowitz JD, Khurana TS, Baur JA.

Cell Metab. 2016 Aug 9;24(2):269-82. doi: 10.1016/j.cmet.2016.07.005.


The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 Is Essential for Efficient Hydroxylation of Hypoxia-Inducible Factor α.

Arsenault PR, Song D, Chung YJ, Khurana TS, Lee FS.

Mol Cell Biol. 2016 Aug 26;36(18):2328-43. doi: 10.1128/MCB.00090-16. Print 2016 Sep 15.


Pharmacotherapy to protect the neuromuscular junction after acute organophosphorus pesticide poisoning.

Bird SB, Krajacic P, Sawamoto K, Bunya N, Loro E, Khurana TS.

Ann N Y Acad Sci. 2016 Jun;1374(1):86-93. doi: 10.1111/nyas.13111. Epub 2016 Jun 3. Review.


The NPC2 protein: A novel dog allergen.

Khurana T, Newman-Lindsay S, Young PR, Slater JE.

Ann Allergy Asthma Immunol. 2016 May;116(5):440-446.e2. doi: 10.1016/j.anai.2016.02.006. Epub 2016 Mar 17.


Multiplex Assay for Protein Profiling and Potency Measurement of German Cockroach Allergen Extracts.

Khurana T, Dobrovolskaia E, Shartouny JR, Slater JE.

PLoS One. 2015 Oct 7;10(10):e0140225. doi: 10.1371/journal.pone.0140225. eCollection 2015.


IL-15Rα is a determinant of muscle fuel utilization, and its loss protects against obesity.

Loro E, Seifert EL, Moffat C, Romero F, Mishra MK, Sun Z, Krajacic P, Anokye-Danso F, Summer RS, Ahima RS, Khurana TS.

Am J Physiol Regul Integr Comp Physiol. 2015 Oct 15;309(8):R835-44. doi: 10.1152/ajpregu.00505.2014. Epub 2015 Aug 12.


Intramural Duodenal Hematoma with Acute Pancreatitis in a Patient With an Overt Pancreatic Malignancy.

Khurana T, Shah A, Ali I, Islam R, Siddiqui AA.

ACG Case Rep J. 2014 Jul 8;1(4):209-11. doi: 10.14309/crj.2014.55. eCollection 2014 Jul.


Expression of calcium-buffering proteins in rat intrinsic laryngeal muscles.

Ferretti R, Marques MJ, Khurana TS, Santo Neto H.

Physiol Rep. 2015 Jun;3(6). pii: e12409. doi: 10.14814/phy2.12409.


High risk of acute pancreatitis after endoscopic ultrasound-guided fine needle aspiration of side branch intraductal papillary mucinous neoplasms.

Siddiqui AA, Shahid H, Shah A, Khurana T, Huntington W, Ghumman SS, Loren DE, Kowalski TE, Laique S, Hayat U, Eloubeidi MA.

Endosc Ultrasound. 2015 Apr-Jun;4(2):109-14. doi: 10.4103/2303-9027.156728.


Exercise protocol induces muscle, tendon, and bone adaptations in the rat shoulder.

Rooney SI, Loro E, Sarver JJ, Peltz CD, Hast MW, Tseng WJ, Kuntz AF, Liu XS, Khurana TS, Soslowsky LJ.

Muscles Ligaments Tendons J. 2015 Feb 5;4(4):413-9. eCollection 2014 Oct-Dec.


Anesthetic management of a parturient with glioma brain for cesarean section immediately followed by craniotomy.

Khurana T, Taneja B, Saxena KN.

J Anaesthesiol Clin Pharmacol. 2014 Jul;30(3):397-9. doi: 10.4103/0970-9185.137275.


Characterization of an anti-Bla g 1 scFv: epitope mapping and cross-reactivity.

Mueller GA, Ankney JA, Glesner J, Khurana T, Edwards LL, Pedersen LC, Perera L, Slater JE, Pomés A, London RE.

Mol Immunol. 2014 Jun;59(2):200-7. doi: 10.1016/j.molimm.2014.02.003. Epub 2014 Mar 22.


A mouse model for dominant collagen VI disorders: heterozygous deletion of Col6a3 Exon 16.

Pan TC, Zhang RZ, Arita M, Bogdanovich S, Adams SM, Gara SK, Wagener R, Khurana TS, Birk DE, Chu ML.

J Biol Chem. 2014 Apr 11;289(15):10293-307. doi: 10.1074/jbc.M114.549311. Epub 2014 Feb 22.


Bla g 3: a novel allergen of German cockroach identified using cockroach-specific avian single-chain variable fragment antibody.

Khurana T, Collison M, Chew FT, Slater JE.

Ann Allergy Asthma Immunol. 2014 Feb;112(2):140-145.e1. doi: 10.1016/j.anai.2013.11.007. Epub 2013 Dec 5.


Use of OpdA, an organophosphorus (OP) hydrolase, prevents lethality in an African green monkey model of acute OP poisoning.

Jackson CJ, Carville A, Ward J, Mansfield K, Ollis DL, Khurana T, Bird SB.

Toxicology. 2014 Mar 20;317:1-5. doi: 10.1016/j.tox.2014.01.003. Epub 2014 Jan 18.


Undifferentiated Carcinoma with Osteoclast-Like Giant Cells of the Pancreas in a Patient with New Diagnosis of Follicular Non-Hodgkin's Lymphoma.

Shah A, Khurana T, Freid L, Siddiqui AA.

ACG Case Rep J. 2014 Jan 10;1(2):109-11. doi: 10.14309/crj.2014.17. eCollection 2014 Jan.


FER-1/Dysferlin promotes cholinergic signaling at the neuromuscular junction in C. elegans and mice.

Krajacic P, Pistilli EE, Tanis JE, Khurana TS, Lamitina ST.

Biol Open. 2013 Oct 15;2(11):1245-52. doi: 10.1242/bio.20135637. eCollection 2013.


The nuclear receptor Rev-erbα controls circadian thermogenic plasticity.

Gerhart-Hines Z, Feng D, Emmett MJ, Everett LJ, Loro E, Briggs ER, Bugge A, Hou C, Ferrara C, Seale P, Pryma DA, Khurana TS, Lazar MA.

Nature. 2013 Nov 21;503(7476):410-413. doi: 10.1038/nature12642. Epub 2013 Oct 27.


A knock-in mouse model of human PHD2 gene-associated erythrocytosis establishes a haploinsufficiency mechanism.

Arsenault PR, Pei F, Lee R, Kerestes H, Percy MJ, Keith B, Simon MC, Lappin TR, Khurana TS, Lee FS.

J Biol Chem. 2013 Nov 22;288(47):33571-84. doi: 10.1074/jbc.M113.482364. Epub 2013 Oct 11.


Ventilatory chemosensory drive is blunted in the mdx mouse model of Duchenne Muscular Dystrophy (DMD).

Mosqueira M, Baby SM, Lahiri S, Khurana TS.

PLoS One. 2013 Jul 29;8(7):e69567. doi: 10.1371/journal.pone.0069567. Print 2013.


Hypoparathyroidism presenting as cognitive dysfunction.

Kumar G, Kaur D, Aggarwal P, Khurana T.

BMJ Case Rep. 2013 May 23;2013. pii: bcr2013009220. doi: 10.1136/bcr-2013-009220.


Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutation.

Tan Q, Kerestes H, Percy MJ, Pietrofesa R, Chen L, Khurana TS, Christofidou-Solomidou M, Lappin TR, Lee FS.

J Biol Chem. 2013 Jun 14;288(24):17134-44. doi: 10.1074/jbc.M112.444059. Epub 2013 May 2.


COL6A3 protein deficiency in mice leads to muscle and tendon defects similar to human collagen VI congenital muscular dystrophy.

Pan TC, Zhang RZ, Markova D, Arita M, Zhang Y, Bogdanovich S, Khurana TS, Bönnemann CG, Birk DE, Chu ML.

J Biol Chem. 2013 May 17;288(20):14320-31. doi: 10.1074/jbc.M112.433078. Epub 2013 Apr 5.


Duchenne muscular dystrophy drug discovery - the application of utrophin promoter activation screening.

Moorwood C, Khurana TS.

Expert Opin Drug Discov. 2013 May;8(5):569-81. doi: 10.1517/17460441.2013.777040. Epub 2013 Mar 9. Review.


Glucoamylase is a potential allergen in products expressed in Neurospora crassa.

Khurana T, Collison M, Le Haynes B, Cambareri E, Slater JE.

Ann Allergy Asthma Immunol. 2013 Feb;110(2):124-5.e3. doi: 10.1016/j.anai.2012.11.021. Epub 2012 Dec 20. No abstract available.


Pharmacology of myopia and potential role for intrinsic retinal circadian rhythms.

Stone RA, Pardue MT, Iuvone PM, Khurana TS.

Exp Eye Res. 2013 Sep;114:35-47. doi: 10.1016/j.exer.2013.01.001. Epub 2013 Jan 8. Review.


Update on the FDA/CBER allergen standardization program.

Khurana T, Slater JE.

Arb Paul Ehrlich Inst Bundesinstitut Impfstoffe Biomed Arzneim Langen Hess. 2013;97:37-44. No abstract available.


A cell-based high-throughput screening assay for posttranscriptional utrophin upregulation.

Moorwood C, Soni N, Patel G, Wilton SD, Khurana TS.

J Biomol Screen. 2013 Apr;18(4):400-6. doi: 10.1177/1087057112465648. Epub 2012 Oct 30.


Expression profiling reveals novel hypoxic biomarkers in peripheral blood of adult mice exposed to chronic hypoxia.

Mosqueira M, Willmann G, Zeiger U, Khurana TS.

PLoS One. 2012;7(5):e37497. doi: 10.1371/journal.pone.0037497. Epub 2012 May 22.


TOR complex 2 (TORC2) in Dictyostelium suppresses phagocytic nutrient capture independently of TORC1-mediated nutrient sensing.

Rosel D, Khurana T, Majithia A, Huang X, Bhandari R, Kimmel AR.

J Cell Sci. 2012 Jan 1;125(Pt 1):37-48. doi: 10.1242/jcs.077040. Epub 2012 Jan 20.


Translational regulation of utrophin by miRNAs.

Basu U, Lozynska O, Moorwood C, Patel G, Wilton SD, Khurana TS.

PLoS One. 2011;6(12):e29376. doi: 10.1371/journal.pone.0029376. Epub 2011 Dec 27.


Drug discovery for Duchenne muscular dystrophy via utrophin promoter activation screening.

Moorwood C, Lozynska O, Suri N, Napper AD, Diamond SL, Khurana TS.

PLoS One. 2011;6(10):e26169. doi: 10.1371/journal.pone.0026169. Epub 2011 Oct 20.


Loss of IL-15 receptor α alters the endurance, fatigability, and metabolic characteristics of mouse fast skeletal muscles.

Pistilli EE, Bogdanovich S, Garton F, Yang N, Gulbin JP, Conner JD, Anderson BG, Quinn LS, North K, Ahima RS, Khurana TS.

J Clin Invest. 2011 Aug;121(8):3120-32. doi: 10.1172/JCI44945. Epub 2011 Jul 18.


Image defocus and altered retinal gene expression in chick: clues to the pathogenesis of ametropia.

Stone RA, McGlinn AM, Baldwin DA, Tobias JW, Iuvone PM, Khurana TS.

Invest Ophthalmol Vis Sci. 2011 Jul 29;52(8):5765-77. doi: 10.1167/iovs.10-6727.


Targeting the activin type IIB receptor to improve muscle mass and function in the mdx mouse model of Duchenne muscular dystrophy.

Pistilli EE, Bogdanovich S, Goncalves MD, Ahima RS, Lachey J, Seehra J, Khurana T.

Am J Pathol. 2011 Mar;178(3):1287-97. doi: 10.1016/j.ajpath.2010.11.071.


Biglycan recruits utrophin to the sarcolemma and counters dystrophic pathology in mdx mice.

Amenta AR, Yilmaz A, Bogdanovich S, McKechnie BA, Abedi M, Khurana TS, Fallon JR.

Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):762-7. doi: 10.1073/pnas.1013067108. Epub 2010 Dec 27.


Chronic hypoxia impairs muscle function in the Drosophila model of Duchenne's muscular dystrophy (DMD).

Mosqueira M, Willmann G, Ruohola-Baker H, Khurana TS.

PLoS One. 2010 Oct 20;5(10):e13450. doi: 10.1371/journal.pone.0013450.


Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition.

Goncalves MD, Pistilli EE, Balduzzi A, Birnbaum MJ, Lachey J, Khurana TS, Ahima RS.

PLoS One. 2010 Sep 15;5(9):e12707. doi: 10.1371/journal.pone.0012707.

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