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Activity Intensity, Volume, and Norms: Utility and Interpretation of Accelerometer Metrics.

Rowlands AV, Fairclough SJ, Yates T, Edwardson CL, Davies M, Munir F, Khunti K, Stiles VH.

Med Sci Sports Exerc. 2019 Jul 12. doi: 10.1249/MSS.0000000000002047. [Epub ahead of print]


Differential left ventricular and left atrial remodelling in heart failure with preserved ejection fraction patients with and without diabetes.

Gulsin GS, Kanagala P, Chan DCS, Cheng ASH, Athithan L, Graham-Brown MPM, Singh A, Yang J, Li Z, Khunti K, Davies MJ, Arnold JR, Squire IB, Ng LL, McCann GP.

Ther Adv Endocrinol Metab. 2019 Jul 5;10:2042018819861593. doi: 10.1177/2042018819861593. eCollection 2019.


Treatment patterns and associated factors in 14 668 people with type 2 diabetes initiating a second-line therapy: results from the global DISCOVER study programme.

Nicolucci A, Charbonnel B, Gomes MB, Khunti K, Kosiborod M, Shestakova MV, Shimomura I, Watada H, Chen H, Cid-Razufa J, Fenici P, Hammar N, Surmont F, Tang F, Pocock S.

Diabetes Obes Metab. 2019 Jul 12. doi: 10.1111/dom.13830. [Epub ahead of print]


A data-driven, meaningful, easy to interpret, standardised accelerometer outcome variable for global surveillance.

Rowlands AV, Sherar LB, Fairclough SJ, Yates T, Edwardson CL, Harrington DM, Davies MJ, Munir F, Khunti K, Stiles VH.

J Sci Med Sport. 2019 Jul 1. pii: S1440-2440(19)30249-X. doi: 10.1016/j.jsams.2019.06.016. [Epub ahead of print]


Type 2 diabetes treatment and outcomes worldwide: A short review of the DISCOVER study programme.

Khunti K, Ji L, Medina J, Surmont F, Kosiborod M.

Diabetes Obes Metab. 2019 Jun 19. doi: 10.1111/dom.13817. [Epub ahead of print] Review.


Physical activity, multimorbidity, and life expectancy: a UK Biobank longitudinal study.

Chudasama YV, Khunti KK, Zaccardi F, Rowlands AV, Yates T, Gillies CL, Davies MJ, Dhalwani NN.

BMC Med. 2019 Jun 12;17(1):108. doi: 10.1186/s12916-019-1339-0.


Aspirin has potential benefits for primary prevention of cardiovascular outcomes in diabetes: updated literature-based and individual participant data meta-analyses of randomized controlled trials.

Seidu S, Kunutsor SK, Sesso HD, Gaziano JM, Buring JE, Roncaglioni MC, Khunti K.

Cardiovasc Diabetol. 2019 Jun 3;18(1):70. doi: 10.1186/s12933-019-0875-4. Review.


Self-Compassion, Metabolic Control and Health Status in Individuals with Type 2 Diabetes: A UK Observational Study.

Morrison AE, Zaccardi F, Chatterjee S, Brady E, Doherty Y, Robertson N, Hadjiconstantinou M, Daniels L, Hall A, Khunti K, Davies MJ.

Exp Clin Endocrinol Diabetes. 2019 Jun 3. doi: 10.1055/a-0897-3772. [Epub ahead of print]


A fitting problem: Standardising shoe fit standards to reduce related diabetic foot ulcers.

Jones PJ, Bibb RJ, Davies MJ, Khunti K, McCarthy M, Fong DTP, Webb D.

Diabetes Res Clin Pract. 2019 May 22;154:66-74. doi: 10.1016/j.diabres.2019.05.017. [Epub ahead of print] Review.


Eligibility of patients with type 2 diabetes for sodium-glucose cotransporter 2 inhibitor cardiovascular outcomes trials: a global perspective from the DISCOVER study.

Pintat S, Fenici P, Hammar N, Ji L, Khunti K, Medina J, Tang F, Wittbrodt E, Surmont F.

BMJ Open Diabetes Res Care. 2019 Mar 21;7(1):e000627. doi: 10.1136/bmjdrc-2018-000627. eCollection 2019.


Therapeutic inertia in type 2 diabetes: prevalence, causes, consequences and methods to overcome inertia.

Khunti S, Khunti K, Seidu S.

Ther Adv Endocrinol Metab. 2019 May 3;10:2042018819844694. doi: 10.1177/2042018819844694. eCollection 2019. Review.


Biological variation of measured and estimated glomerular filtration rate in patients with chronic kidney disease.

Rowe C, Sitch AJ, Barratt J, Brettell EA, Cockwell P, Dalton RN, Deeks JJ, Eaglestone G, Pellatt-Higgins T, Kalra PA, Khunti K, Loud FC, Morris FS, Ottridge RS, Stevens PE, Sharpe CC, Sutton AJ, Taal MW, Lamb EJ; eGFR-C study group.

Kidney Int. 2019 Mar 7. pii: S0085-2538(19)30274-1. doi: 10.1016/j.kint.2019.02.021. [Epub ahead of print]


Association of depression and anxiety with clinical, sociodemographic, lifestyle and environmental factors in South Asian and white European individuals at high risk of diabetes.

Razieh C, Khunti K, Davies MJ, Edwardson CL, Henson J, Darko N, Comber A, Jones A, Yates T.

Diabet Med. 2019 May 12. doi: 10.1111/dme.13986. [Epub ahead of print]


Comparative Relevance of Physical Fitness and Adiposity on Life Expectancy: A UK Biobank Observational Study.

Zaccardi F, Davies MJ, Khunti K, Yates T.

Mayo Clin Proc. 2019 Jun;94(6):985-994. doi: 10.1016/j.mayocp.2018.10.029. Epub 2019 May 9.


Objective measures of non-adherence in cardiometabolic diseases: a review focused on urine biochemical screening.

Lane D, Patel P, Khunti K, Gupta P.

Patient Prefer Adherence. 2019 Apr 12;13:537-547. doi: 10.2147/PPA.S162215. eCollection 2019. Review.


Effectiveness of psychoeducational interventions for the treatment of diabetes-specific emotional distress and glycaemic control in people with type 2 diabetes: A systematic review and meta-analysis.

Perrin N, Bodicoat DH, Davies MJ, Robertson N, Snoek FJ, Khunti K.

Prim Care Diabetes. 2019 Apr 27. pii: S1751-9918(19)30145-7. doi: 10.1016/j.pcd.2019.04.001. [Epub ahead of print]


Statin Use in Primary Prevention: A Simple Trial-Based Approach Compared With Guideline-Recommended Risk Algorithms for Selection of Eligible Patients.

Khunti K, Jung H, Dans AL, Held C, Dagenais GR, Yusuf S, Lonn E.

Can J Cardiol. 2019 May;35(5):644-652. doi: 10.1016/j.cjca.2019.03.002. Epub 2019 Mar 19.


Temporal variation of renal function in people with type 2 diabetes mellitus: A retrospective UK clinical practice research datalink cohort study.

Spanopoulos D, Okhai H, Zaccardi F, Tebboth A, Barrett B, Busse M, Webb J, Khunti K.

Diabetes Obes Metab. 2019 Aug;21(8):1817-1823. doi: 10.1111/dom.13734. Epub 2019 May 6.


Selectivity of beta-blockers, cardiovascular and all-cause mortality in people with hypoglycaemia: An observational study.

Zaccardi F, Nystrup Husemoen LL, Thorsted BL, Webb DR, Paul SK, Davies MJ, Khunti K.

Nutr Metab Cardiovasc Dis. 2019 May;29(5):481-488. doi: 10.1016/j.numecd.2019.01.006. Epub 2019 Feb 16.


Deintensification in older patients with type 2 diabetes: A systematic review of approaches, rates and outcomes.

Seidu S, Kunutsor SK, Topsever P, Hambling CE, Cos FX, Khunti K.

Diabetes Obes Metab. 2019 Jul;21(7):1668-1679. doi: 10.1111/dom.13724. Epub 2019 Apr 29.


Response to commentary by Rhew and colleagues on: Depression, antidepressant use, and risk of venous thromboembolism: systematic review and meta-analysis of published observational evidence.

Kunutsor SK, Seidu S, Khunti K.

Ann Med. 2019 Feb;51(1):99-100. doi: 10.1080/07853890.2019.1581942. Epub 2019 Apr 1. No abstract available.


Rationale, design and study protocol of the randomised controlled trial: Diabetes Interventional Assessment of Slimming or Training tO Lessen Inconspicuous Cardiovascular Dysfunction (the DIASTOLIC study).

Gulsin GS, Brady EM, Swarbrick DJ, Athithan L, Henson J, Baldry E, McAdam J, Marsh AM, Parke KS, Wormleighton JV, Levelt E, Yates T, Bodicoat D, Khunti K, Davies MJ, McCann GP.

BMJ Open. 2019 Mar 30;9(3):e023207. doi: 10.1136/bmjopen-2018-023207.


Efficacy of low- and very-low-energy diets in people with type 2 diabetes mellitus: A systematic review and meta-analysis of interventional studies.

Kloecker DE, Zaccardi F, Baldry E, Davies MJ, Khunti K, Webb DR.

Diabetes Obes Metab. 2019 Jul;21(7):1695-1705. doi: 10.1111/dom.13727. Epub 2019 Apr 29.


Authors' Reply to Gough: "Achieving Glycaemic Control with Concentrated Insulin in Patients with Type 2 Diabetes".

Chatterjee S, Khunti K, Davies M.

Drugs. 2019 Apr;79(6):683-684. doi: 10.1007/s40265-019-01093-1. No abstract available.


Treatment of type 2 diabetes mellitus worldwide: Baseline patient characteristics in the global DISCOVER study.

Gomes MB, Rathmann W, Charbonnel B, Khunti K, Kosiborod M, Nicolucci A, Pocock SJ, Shestakova MV, Shimomura I, Tang F, Watada H, Chen H, Cid-Ruzafa J, Fenici P, Hammar N, Surmont F, Ji L; DISCOVER investigators.

Diabetes Res Clin Pract. 2019 May;151:20-32. doi: 10.1016/j.diabres.2019.03.024. Epub 2019 Mar 20.


Biochemical Urine Testing of Adherence to Cardiovascular Medications Reveals High Rates of Nonadherence in People Attending Their Annual Review for Type 2 Diabetes.

Patel P, Gupta P, Burns A, Mohamed AA, Cole R, Lane D, Seidu S, Khunti K.

Diabetes Care. 2019 Jun;42(6):1132-1135. doi: 10.2337/dc18-1453. Epub 2019 Mar 18.


Corrections to: Achieving Glycaemic Control with Concentrated Insulin in Patients with Type 2 Diabetes.

Chatterjee S, Khunti K, Davies MJ.

Drugs. 2019 Apr;79(6):685. doi: 10.1007/s40265-019-01094-0.


Incidence and severity of hypoglycaemia in type 2 diabetes by treatment regimen: A UK multisite 12-month prospective observational study.

Dunkley AJ, Fitzpatrick C, Gray LJ, Waheed G, Heller SR, Frier BM, Davies MJ, Khunti K; Primary Care Diabetes Society.

Diabetes Obes Metab. 2019 Jul;21(7):1585-1595. doi: 10.1111/dom.13690. Epub 2019 Apr 4.


Effects of blood pressure and lipid lowering on cognition: Results from the HOPE-3 study.

Bosch J, O'Donnell M, Swaminathan B, Lonn EM, Sharma M, Dagenais G, Diaz R, Khunti K, Lewis BS, Avezum A, Held C, Keltai M, Reid C, Toff WD, Dans A, Leiter LA, Sliwa K, Lee SF, Pogue JM, Hart R, Yusuf S; HOPE-3 Investigators.

Neurology. 2019 Mar 26;92(13):e1435-e1446. doi: 10.1212/WNL.0000000000007174. Epub 2019 Feb 27.


Association of smoking and cardiometabolic parameters with albuminuria in people with type 2 diabetes mellitus: a systematic review and meta-analysis.

Kar D, Gillies C, Nath M, Khunti K, Davies MJ, Seidu S.

Acta Diabetol. 2019 Aug;56(8):839-850. doi: 10.1007/s00592-019-01293-x. Epub 2019 Feb 24. Review.


Factors influencing safe glucose-lowering in older adults with type 2 diabetes: A PeRsOn-centred ApproaCh To IndiVidualisEd (PROACTIVE) Glycemic Goals for older people: A position statement of Primary Care Diabetes Europe.

Hambling CE, Khunti K, Cos X, Wens J, Martinez L, Topsever P, Del Prato S, Sinclair A, Schernthaner G, Rutten G, Seidu S.

Prim Care Diabetes. 2019 Aug;13(4):330-352. doi: 10.1016/j.pcd.2018.12.005. Epub 2019 Feb 18.


Therapeutic Inertia and the Legacy of Dysglycemia on the Microvascular and Macrovascular Complications of Diabetes.

Khunti K, Seidu S.

Diabetes Care. 2019 Mar;42(3):349-351. doi: 10.2337/dci18-0030. No abstract available.


A school-based intervention (‘Girls Active’) to increase physical activity levels among 11- to 14-year-old girls: cluster RCT.

Harrington DM, Davies MJ, Bodicoat D, Charles JM, Chudasama YV, Gorely T, Khunti K, Rowlands AV, Sherar LB, Tudor-Edwards R, Yates T, Edwardson CL.

Southampton (UK): NIHR Journals Library; 2019 Feb.


The Diabetes Unmet Need with Basal Insulin Evaluation (DUNE) study in type 2 diabetes: Achieving HbA1c targets with basal insulin in a real-world setting.

Meneghini LF, Mauricio D, Orsi E, Lalic NM, Cali AMG, Westerbacka J, Stella P, Candelas Dea C, Pilorget V, Perfetti R, Khunti K; DUNE investigators.

Diabetes Obes Metab. 2019 Jun;21(6):1429-1436. doi: 10.1111/dom.13673. Epub 2019 Mar 28.


The Standard of Care in Type 2 Diabetes: Re-evaluating the Treatment Paradigm.

Mohan V, Cooper ME, Matthews DR, Khunti K.

Diabetes Ther. 2019 Mar;10(Suppl 1):1-13. doi: 10.1007/s13300-019-0573-y. Epub 2019 Feb 13. Review.


Glycaemic control after treatment intensification in patients with type 2 diabetes uncontrolled on two or more non-insulin antidiabetic drugs in a real-world setting.

Canivell S, Mata-Cases M, Real J, Franch-Nadal J, Vlacho B, Khunti K, Gratacòs M, Mauricio D.

Diabetes Obes Metab. 2019 Jun;21(6):1373-1380. doi: 10.1111/dom.13663. Epub 2019 Mar 19.


Correction to: Achieving Glycaemic Control with Concentrated Insulin in Patients with Type 2 Diabetes.

Chatterjee S, Khunti K, Davies MJ.

Drugs. 2019 Feb;79(2):187. doi: 10.1007/s40265-019-1063-2.


Update on the General Practice Optimising Structured Monitoring to Improve Clinical Outcomes in Type 2 Diabetes (GP-OSMOTIC) trial: statistical analysis plan for a multi-centre randomised controlled trial.

Thuraisingam S, Chondros P, Catchpool M, Dalziel K, Manski-Nankervis JA, Speight J, Holmes-Truscott E, Audehm R, Chiang J, Blackberry I, O'Neal D, Khunti K, Best J, Furler J.

Trials. 2019 Jan 30;20(1):93. doi: 10.1186/s13063-018-3126-1.


Differences in objectively measured physical activity and sedentary behaviour between white Europeans and south Asians recruited from primary care: cross-sectional analysis of the PROPELS trial.

Biddle GJH, Edwardson CL, Rowlands AV, Davies MJ, Bodicoat DH, Hardeman W, Eborall H, Sutton S, Griffin S, Khunti K, Yates T.

BMC Public Health. 2019 Jan 21;19(1):95. doi: 10.1186/s12889-018-6341-5.


Cardiovascular efficacy and safety of sodium-glucose co-transporter-2 inhibitors and glucagon-like peptide-1 receptor agonists: a systematic review and network meta-analysis.

Hussein H, Zaccardi F, Khunti K, Seidu S, Davies MJ, Gray LJ.

Diabet Med. 2019 Apr;36(4):444-452. doi: 10.1111/dme.13898. Epub 2019 Jan 30. Review.


Association of Medication Intensity and Stages of Airflow Limitation With the Risk of Hospitalization or Death in Patients With Heart Failure and Chronic Obstructive Pulmonary Disease.

Lawson CA, Mamas MA, Jones PW, Teece L, McCann G, Khunti K, Kadam UT.

JAMA Netw Open. 2018 Dec 7;1(8):e185489. doi: 10.1001/jamanetworkopen.2018.5489.


Association of a Combined Measure of Adherence and Treatment Intensity With Cardiovascular Outcomes in Patients With Atherosclerosis or Other Cardiovascular Risk Factors Treated With Statins and/or Ezetimibe.

Khunti K, Danese MD, Kutikova L, Catterick D, Sorio-Vilela F, Gleeson M, Kondapally Seshasai SR, Brownrigg J, Ray KK.

JAMA Netw Open. 2018 Dec 7;1(8):e185554. doi: 10.1001/jamanetworkopen.2018.5554.


Achieving Glycaemic Control with Concentrated Insulin in Patients with Type 2 Diabetes.

Chatterjee S, Khunti K, Davies MJ.

Drugs. 2019 Feb;79(2):173-186. doi: 10.1007/s40265-018-1048-6. Review. Erratum in: Drugs. 2019 Jan 31;:. Drugs. 2019 Apr;79(6):685.


Reply to Mantovani: "Causality between non-alcoholic fatty liver disease and risk of cardiovascular disease and type 2 diabetes".

Zaccardi F, Morrison AE, Khunti K, Davies MJ.

Liver Int. 2019 Apr;39(4):780-781. doi: 10.1111/liv.14026. Epub 2019 Jan 7. No abstract available.


Postpartum monitoring of women with a history of gestational diabetes - A cross-sectional study of an inner-city population.

Fahami R, Dhalwani N, Khunti K, Davies M, Seidu S.

Prim Care Diabetes. 2019 Aug;13(4):376-379. doi: 10.1016/j.pcd.2018.11.010. Epub 2018 Dec 21.


Glycated Hemoglobin Level Goal Achievement in Adults With Type 2 Diabetes in Canada: Still Room for Improvement.

Leiter LA, Cheng AYY, Ekoé JM, Goldenberg RM, Harris SB, Hramiak IM, Khunti K, Lin PJ, Richard JF, Senior PA, Yale JF, Goldin L, Tan MK, Langer A.

Can J Diabetes. 2018 Nov 2. pii: S1499-2671(18)30370-8. doi: 10.1016/j.jcjd.2018.10.005. [Epub ahead of print]


Baby Steps - a structured group education programme with accompanying mobile web application designed to promote physical activity in women with a history of gestational diabetes: study protocol for a randomised controlled trial.

Sukumar N, Dallosso H, Saravanan P, Yates T, Telling C, Shorthose K, Northern A, Schreder S, Brough C, Gray LJ, Davies MJ, Khunti K.

Trials. 2018 Dec 12;19(1):682. doi: 10.1186/s13063-018-3067-8.


Intensive versus standard multifactorial cardiovascular risk factor control in screen-detected type 2 diabetes: 5-year and longer-term modelled outcomes of the ADDITION-Leicester study.

Webb D, Dales J, Zaccardi F, Hill S, Moore C, Farooqi A, Griffin S, Davies M, Khunti K.

Diabetes Metab Res Rev. 2019 Mar;35(3):e3111. doi: 10.1002/dmrr.3111. Epub 2018 Dec 19.


Structured lifestyle education to support weight loss for people with schizophrenia, schizoaffective disorder and first episode psychosis: the STEPWISE RCT.

Holt RI, Hind D, Gossage-Worrall R, Bradburn MJ, Saxon D, McCrone P, Morris TA, Etherington A, Shiers D, Barnard K, Swaby L, Edwardson C, Carey ME, Davies MJ, Dickens CM, Doherty Y, French P, Greenwood KE, Kalidindi S, Khunti K, Laugharne R, Pendlebury J, Rathod S, Siddiqi N, Wright S, Waller G, Gaughran F, Barnett J, Northern A.

Health Technol Assess. 2018 Nov;22(65):1-160. doi: 10.3310/hta22650.


Vascular complications in patients with type 2 diabetes: prevalence and associated factors in 38 countries (the DISCOVER study program).

Kosiborod M, Gomes MB, Nicolucci A, Pocock S, Rathmann W, Shestakova MV, Watada H, Shimomura I, Chen H, Cid-Ruzafa J, Fenici P, Hammar N, Surmont F, Tang F, Khunti K; DISCOVER investigators.

Cardiovasc Diabetol. 2018 Nov 28;17(1):150. doi: 10.1186/s12933-018-0787-8.

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