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Items: 1 to 50 of 188

1.

Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation.

Starossom SC, Campo Garcia J, Woelfle T, Romero-Suarez S, Olah M, Watanabe F, Cao L, Yeste A, Tukker JJ, Quintana FJ, Imitola J, Witzel F, Schmitz D, Morkel M, Paul F, Infante-Duarte C, Khoury SJ.

Nat Commun. 2019 Jan 15;10(1):217. doi: 10.1038/s41467-018-08140-7.

2.

Safety and Efficacy of Rituximab in Multiple Sclerosis: A Retrospective Observational Study.

Yamout BI, El-Ayoubi NK, Nicolas J, El Kouzi Y, Khoury SJ, Zeineddine MM.

J Immunol Res. 2018 Nov 12;2018:9084759. doi: 10.1155/2018/9084759. eCollection 2018.

3.

Gadoterate Meglumine Administration in Multiple Sclerosis has no Effect on the Dentate Nucleus and the Globus Pallidus Signal Intensities.

Hannoun S, Issa R, El Ayoubi NK, Haddad R, Baalbaki M, Yamout BI, Khoury SJ, Hourani R.

Acad Radiol. 2018 Dec 5. pii: S1076-6332(18)30525-7. doi: 10.1016/j.acra.2018.11.010. [Epub ahead of print]

PMID:
30527456
4.

The Bayesian risk estimate at onset (BREMSO) correlates with cognitive and physical disability in patients with early multiple sclerosis.

Said M, El Ayoubi NK, Hannoun S, Haddad R, Saba L, Jalkh Y, Yamout BI, Khoury SJ.

Mult Scler Relat Disord. 2018 Nov;26:96-102. doi: 10.1016/j.msard.2018.09.003. Epub 2018 Sep 13.

PMID:
30243236
5.

Identification of MS-specific serum miRNAs in an international multicenter study.

Regev K, Healy BC, Paul A, Diaz-Cruz C, Mazzola MA, Raheja R, Glanz BI, Kivisäkk P, Chitnis T, Jagodic M, Piehl F, Olsson T, Khademi M, Hauser S, Oksenberg J, Khoury SJ, Weiner HL, Gandhi R.

Neurol Neuroimmunol Neuroinflamm. 2018 Aug 20;5(5):e491. doi: 10.1212/NXI.0000000000000491. eCollection 2018 Sep.

6.

Gadolinium effect on thalamus and whole brain tissue segmentation.

Hannoun S, Baalbaki M, Haddad R, Saaybi S, El Ayoubi NK, Yamout BI, Khoury SJ, Hourani R.

Neuroradiology. 2018 Nov;60(11):1167-1173. doi: 10.1007/s00234-018-2082-5. Epub 2018 Aug 21.

PMID:
30128599
7.

Efficacy and safety of natalizumab extended interval dosing.

Yamout BI, Sahraian MA, Ayoubi NE, Tamim H, Nicolas J, Khoury SJ, Zeineddine MM.

Mult Scler Relat Disord. 2018 Aug;24:113-116. doi: 10.1016/j.msard.2018.06.015. Epub 2018 Jul 5.

PMID:
29982107
8.

Effectiveness of alternative dose fingolimod for multiple sclerosis.

Longbrake EE, Kantor D, Pawate S, Bradshaw MJ, von Geldern G, Chahin S, Cross AH, Parks BJ, Rice M, Khoury SJ, Yamout B, Zeineddine M, Russell-Giller S, Caminero-Rodriguez A, Edwards K, Lathi E, VanderKodde D, Meador W, Berkovich R, Ge L, Bacon TE, Kister I.

Neurol Clin Pract. 2018 Apr;8(2):102-107. doi: 10.1212/CPJ.0000000000000434.

PMID:
29708225
9.

Foxo1 Promotes Th9 Cell Differentiation and Airway Allergy.

Buttrick TS, Wang W, Yung C, Trieu KG, Patel K, Khoury SJ, Ai X, Elyaman W.

Sci Rep. 2018 Jan 16;8(1):818. doi: 10.1038/s41598-018-19315-z.

10.

Alternative diagnoses in patients referred to specialized centers for suspected MS.

Yamout BI, Khoury SJ, Ayyoubi N, Doumiati H, Fakhreddine M, Ahmed SF, Tamim H, Al-Hashel JY, Behbehani R, Alroughani R.

Mult Scler Relat Disord. 2017 Nov;18:85-89. doi: 10.1016/j.msard.2017.09.016. Epub 2017 Sep 21.

PMID:
29141828
11.

Rebound syndrome after teriflunomide cessation in a patient with multiple sclerosis.

Yamout BI, Said M, Hannoun S, Zeineddine M, Massouh J, Khoury SJ.

J Neurol Sci. 2017 Sep 15;380:79-81. doi: 10.1016/j.jns.2017.07.014. Epub 2017 Jul 9.

PMID:
28870594
12.

SUMMIT (Serially Unified Multicenter Multiple Sclerosis Investigation): creating a repository of deeply phenotyped contemporary multiple sclerosis cohorts.

Bove R, Chitnis T, Cree BA, Tintoré M, Naegelin Y, Uitdehaag BM, Kappos L, Khoury SJ, Montalban X, Hauser SL, Weiner HL; SUMMIT Consortium.

Mult Scler. 2018 Oct;24(11):1485-1498. doi: 10.1177/1352458517726657. Epub 2017 Aug 29.

PMID:
28847219
13.

Opposite functions of STAT3 and Smad3 in regulating Tiam1 expression in Th17 cells.

Buttrick T, Khoury SJ, Elyaman W.

Small GTPases. 2017 Jun 13:1-7. doi: 10.1080/21541248.2017.1341365. [Epub ahead of print]

PMID:
28609201
14.

Effect of vitamin D replacement on immunological biomarkers in patients with multiple sclerosis.

Mrad MF, El Ayoubi NK, Esmerian MO, Kazan JM, Khoury SJ.

Clin Immunol. 2017 Aug;181:9-15. doi: 10.1016/j.clim.2017.05.017. Epub 2017 May 20.

PMID:
28536054
15.

Defects in CD4+ T cell LFA-1 integrin-dependent adhesion and proliferation protect Cd47-/- mice from EAE.

Azcutia V, Bassil R, Herter JM, Engelbertsen D, Newton G, Autio A, Mayadas T, Lichtman AH, Khoury SJ, Parkos CA, Elyaman W, Luscinskas FW.

J Leukoc Biol. 2017 Feb;101(2):493-505. doi: 10.1189/jlb.3A1215-546RR. Epub 2016 Dec 13.

16.

Th9 cells in the pathogenesis of EAE and multiple sclerosis.

Elyaman W, Khoury SJ.

Semin Immunopathol. 2017 Jan;39(1):79-87. doi: 10.1007/s00281-016-0604-y. Epub 2016 Nov 14. Review.

PMID:
27844107
17.

Blood Biomarkers as Outcome Measures in Inflammatory Neurologic Diseases.

El Ayoubi NK, Khoury SJ.

Neurotherapeutics. 2017 Jan;14(1):135-147. doi: 10.1007/s13311-016-0486-7. Review.

18.

Tiam1/Rac1 complex controls Il17a transcription and autoimmunity.

Kurdi AT, Bassil R, Olah M, Wu C, Xiao S, Taga M, Frangieh M, Buttrick T, Orent W, Bradshaw EM, Khoury SJ, Elyaman W.

Nat Commun. 2016 Oct 11;7:13048. doi: 10.1038/ncomms13048.

19.

Three cases of herpes zoster radiculitis in MS patients treated with natalizumab.

Yamout BI, Abou Zeid N, Taha AJ, Zeineddine MM, Khoury SJ.

Mult Scler Relat Disord. 2016 Sep;9:122-4. doi: 10.1016/j.msard.2016.07.012. Epub 2016 Jul 25.

PMID:
27645358
20.

Retinal measures correlate with cognitive and physical disability in early multiple sclerosis.

El Ayoubi NK, Ghassan S, Said M, Allam J, Darwish H, Khoury SJ.

J Neurol. 2016 Nov;263(11):2287-2295. Epub 2016 Aug 20.

PMID:
27544501
21.

ACCLAIM: A randomized trial of abatacept (CTLA4-Ig) for relapsing-remitting multiple sclerosis.

Khoury SJ, Rochon J, Ding L, Byron M, Ryker K, Tosta P, Gao W, Freedman MS, Arnold DL, Sayre PH, Smilek DE; ACCLAIM Study Group.

Mult Scler. 2017 Apr;23(5):686-695. doi: 10.1177/1352458516662727. Epub 2016 Aug 5.

22.

Imaging in multiple sclerosis: A new spin on lesions.

Bou Fakhredin R, Saade C, Kerek R, El-Jamal L, Khoury SJ, El-Merhi F.

J Med Imaging Radiat Oncol. 2016 Oct;60(5):577-586. doi: 10.1111/1754-9485.12498. Epub 2016 Jul 27. Review.

PMID:
27464473
23.

Medical Research Volunteer Program (MRVP): innovative program promoting undergraduate research in the medical field.

Dagher MM, Atieh JA, Soubra MK, Khoury SJ, Tamim H, Kaafarani BR.

BMC Med Educ. 2016 Jun 6;16:160. doi: 10.1186/s12909-016-0670-9.

24.

Comparative effect of 25(OH)D3 and 1,25(OH)2D3 on Th17 cell differentiation.

Fawaz L, Mrad MF, Kazan JM, Sayegh S, Akika R, Khoury SJ.

Clin Immunol. 2016 May;166-167:59-71. doi: 10.1016/j.clim.2016.02.011. Epub 2016 Apr 1.

PMID:
27041081
25.

JC virus seroprevalence and seroconversion in multiple sclerosis cohort: A Middle-Eastern study.

Alroughani R, Akhtar S, Ahmed SF, Khoury SJ, Al-Hashel JY, Sahraian MA, Al Jumah M, Zeineddine M, Farhat S, Doumiati H, Yamout BI.

J Neurol Sci. 2016 Jan 15;360:61-5. doi: 10.1016/j.jns.2015.11.044. Epub 2015 Nov 24.

PMID:
26723975
26.

Safety and efficacy of fingolimod in clinical practice: The experience of an academic center in the Middle East.

Yamout BI, Zeineddine MM, Tamim H, Khoury SJ.

J Neuroimmunol. 2015 Dec 15;289:93-7. doi: 10.1016/j.jneuroim.2015.10.015. Epub 2015 Oct 26.

PMID:
26616877
27.

Rheumatoid arthritis-associated RBPJ polymorphism alters memory CD4+ T cells.

Orent W, Mchenry AR, Rao DA, White C, Klein HU, Bassil R, Srivastava G, Replogle JM, Raj T, Frangieh M, Cimpean M, Cuerdon N, Chibnik L, Khoury SJ, Karlson EW, Brenner MB, De Jager P, Bradshaw EM, Elyaman W.

Hum Mol Genet. 2016 Jan 15;25(2):404-17. doi: 10.1093/hmg/ddv474. Epub 2015 Nov 24.

28.

Serum 25-hydroxyvitamin D predicts cognitive performance in adults.

Darwish H, Zeinoun P, Ghusn H, Khoury B, Tamim H, Khoury SJ.

Neuropsychiatr Dis Treat. 2015 Aug 25;11:2217-23. doi: 10.2147/NDT.S87014. eCollection 2015.

29.

Safety and efficacy of reduced fingolimod dosage treatment.

Yamout BI, Zeineddine MM, Sawaya RA, Khoury SJ.

J Neuroimmunol. 2015 Aug 15;285:13-5. doi: 10.1016/j.jneuroim.2015.05.012. Epub 2015 May 15.

PMID:
26198913
30.

Cell surface glycan engineering of neural stem cells augments neurotropism and improves recovery in a murine model of multiple sclerosis.

Merzaban JS, Imitola J, Starossom SC, Zhu B, Wang Y, Lee J, Ali AJ, Olah M, Abuelela AF, Khoury SJ, Sackstein R.

Glycobiology. 2015 Dec;25(12):1392-409. doi: 10.1093/glycob/cwv046. Epub 2015 Jul 7.

31.

Risk factors for multiple sclerosis and associations with anti-EBV antibody titers.

Mouhieddine TH, Darwish H, Fawaz L, Yamout B, Tamim H, Khoury SJ.

Clin Immunol. 2015 May;158(1):59-66. doi: 10.1016/j.clim.2015.03.011. Epub 2015 Mar 21.

PMID:
25805657
32.

Effect of natalizumab treatment on circulating plasmacytoid dendritic cells: a cross-sectional observational study in patients with multiple sclerosis.

Kivisäkk P, Francois K, Mbianda J, Gandhi R, Weiner HL, Khoury SJ.

PLoS One. 2014 Jul 30;9(7):e103716. doi: 10.1371/journal.pone.0103716. eCollection 2014.

33.

BCL6 controls Th9 cell development by repressing Il9 transcription.

Bassil R, Orent W, Olah M, Kurdi AT, Frangieh M, Buttrick T, Khoury SJ, Elyaman W.

J Immunol. 2014 Jul 1;193(1):198-207. doi: 10.4049/jimmunol.1303184. Epub 2014 May 30.

34.

Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus.

Ottoboni L, Frohlich IY, Lee M, Healy BC, Keenan BT, Xia Z, Chitnis T, Guttmann CR, Khoury SJ, Weiner HL, Hafler DA, De Jager PL.

Neurology. 2013 Nov 26;81(22):1891-9. doi: 10.1212/01.wnl.0000436612.66328.8a. Epub 2013 Oct 30.

35.

Sex influences in autoimmune disease.

Chitnis T, Khoury SJ.

Clin Immunol. 2013 Nov;149(2):169. doi: 10.1016/j.clim.2013.08.002. Epub 2013 Aug 9. No abstract available.

PMID:
24012474
36.

Evaluation of circulating osteopontin levels in an unselected cohort of patients with multiple sclerosis: relevance for biomarker development.

Kivisäkk P, Healy BC, Francois K, Gandhi R, Gholipour T, Egorova S, Sevdalinova V, Quintana F, Chitnis T, Weiner HL, Khoury SJ.

Mult Scler. 2014 Apr;20(4):438-44. doi: 10.1177/1352458513503052. Epub 2013 Sep 4.

PMID:
24005026
37.

IL-4 and retinoic acid synergistically induce regulatory dendritic cells expressing Aldh1a2.

Zhu B, Buttrick T, Bassil R, Zhu C, Olah M, Wu C, Xiao S, Orent W, Elyaman W, Khoury SJ.

J Immunol. 2013 Sep 15;191(6):3139-51. doi: 10.4049/jimmunol.1300329. Epub 2013 Aug 19.

38.

Increased Th17 response to myelin peptides in pediatric MS.

Vargas-Lowy D, Kivisäkk P, Gandhi R, Raddassi K, Soltany P, Gorman MP, Khoury SJ, Chitnis T.

Clin Immunol. 2013 Mar;146(3):176-84. doi: 10.1016/j.clim.2012.12.008. Epub 2012 Dec 28.

PMID:
23352968
39.

An RNA profile identifies two subsets of multiple sclerosis patients differing in disease activity.

Ottoboni L, Keenan BT, Tamayo P, Kuchroo M, Mesirov JP, Buckle GJ, Khoury SJ, Hafler DA, Weiner HL, De Jager PL.

Sci Transl Med. 2012 Sep 26;4(153):153ra131.

40.

In vitro and in vivo studies of IgG-derived Treg epitopes (Tregitopes): a promising new tool for tolerance induction and treatment of autoimmunity.

Cousens LP, Najafian N, Mingozzi F, Elyaman W, Mazer B, Moise L, Messitt TJ, Su Y, Sayegh M, High K, Khoury SJ, Scott DW, De Groot AS.

J Clin Immunol. 2013 Jan;33 Suppl 1:S43-9. doi: 10.1007/s10875-012-9762-4. Epub 2012 Sep 2. Review.

41.

Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration.

Starossom SC, Mascanfroni ID, Imitola J, Cao L, Raddassi K, Hernandez SF, Bassil R, Croci DO, Cerliani JP, Delacour D, Wang Y, Elyaman W, Khoury SJ, Rabinovich GA.

Immunity. 2012 Aug 24;37(2):249-63. doi: 10.1016/j.immuni.2012.05.023. Epub 2012 Aug 9.

42.

Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells.

Purwar R, Schlapbach C, Xiao S, Kang HS, Elyaman W, Jiang X, Jetten AM, Khoury SJ, Fuhlbrigge RC, Kuchroo VK, Clark RA, Kupper TS.

Nat Med. 2012 Aug;18(8):1248-53. doi: 10.1038/nm.2856. Epub 2012 Jul 8.

43.

Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells.

Elyaman W, Bassil R, Bradshaw EM, Orent W, Lahoud Y, Zhu B, Radtke F, Yagita H, Khoury SJ.

Immunity. 2012 Apr 20;36(4):623-34. doi: 10.1016/j.immuni.2012.01.020. Epub 2012 Apr 12.

44.

The impact of lesion in-painting and registration methods on voxel-based morphometry in detecting regional cerebral gray matter atrophy in multiple sclerosis.

Ceccarelli A, Jackson JS, Tauhid S, Arora A, Gorky J, Dell'Oglio E, Bakshi A, Chitnis T, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R, Neema M.

AJNR Am J Neuroradiol. 2012 Sep;33(8):1579-85. doi: 10.3174/ajnr.A3083. Epub 2012 Mar 29.

45.

Type17 T-cells in central nervous system autoimmunity and tumors.

Okada H, Khoury SJ.

J Clin Immunol. 2012 Aug;32(4):802-8. doi: 10.1007/s10875-012-9686-z. Epub 2012 Mar 28. Review.

46.

Immune modulation by Lacto-N-fucopentaose III in experimental autoimmune encephalomyelitis.

Zhu B, Trikudanathan S, Zozulya AL, Sandoval-Garcia C, Kennedy JK, Atochina O, Norberg T, Castagner B, Seeberger P, Fabry Z, Harn D, Khoury SJ, Guleria I.

Clin Immunol. 2012 Mar;142(3):351-61. doi: 10.1016/j.clim.2011.12.006. Epub 2011 Dec 30.

47.

Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: a longitudinal study.

Moodie J, Healy BC, Buckle GJ, Gauthier SA, Glanz BI, Arora A, Ceccarelli A, Tauhid S, Han XM, Venkataraman A, Chitnis T, Khoury SJ, Guttmann CR, Weiner HL, Neema M, Bakshi R.

J Neurol Sci. 2012 Apr 15;315(1-2):49-54. doi: 10.1016/j.jns.2011.11.040. Epub 2011 Dec 28.

48.

Therapeutic strategies in multiple sclerosis.

Comabella M, Khoury SJ.

Clin Immunol. 2012 Jan;142(1):1. doi: 10.1016/j.clim.2011.11.008. Epub 2011 Dec 2. No abstract available.

PMID:
22155340
49.

Potential application of tregitopes as immunomodulating agents in multiple sclerosis.

Elyaman W, Khoury SJ, Scott DW, De Groot AS.

Neurol Res Int. 2011;2011:256460. doi: 10.1155/2011/256460. Epub 2011 Sep 15.

50.

Plasticity of Ly-6C(hi) myeloid cells in T cell regulation.

Zhu B, Kennedy JK, Wang Y, Sandoval-Garcia C, Cao L, Xiao S, Wu C, Elyaman W, Khoury SJ.

J Immunol. 2011 Sep 1;187(5):2418-32. doi: 10.4049/jimmunol.1100403. Epub 2011 Aug 8.

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