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Items: 1 to 50 of 61

1.

Botulinum Toxin in the Management of Children with Cerebral Palsy.

Multani I, Manji J, Hastings-Ison T, Khot A, Graham K.

Paediatr Drugs. 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8.

2.

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study.

Khot A, Brajanovski N, Cameron DP, Hein N, Maclachlan KH, Sanij E, Lim J, Soong J, Link E, Blombery P, Thompson ER, Fellowes A, Sheppard KE, McArthur GA, Pearson RB, Hannan RD, Poortinga G, Harrison SJ.

Cancer Discov. 2019 Aug;9(8):1036-1049. doi: 10.1158/2159-8290.CD-18-1455. Epub 2019 May 15.

PMID:
31092402
3.

Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Siltuximab in High-Risk Smoldering Multiple Myeloma.

Brighton TA, Khot A, Harrison SJ, Ghez D, Weiss BM, Kirsch A, Magen H, Gironella M, Oriol A, Streetly M, Kranenburg B, Qin X, Bandekar R, Hu P, Guilfoyle M, Qi M, Nemat S, Goldschmidt H.

Clin Cancer Res. 2019 Jul 1;25(13):3772-3775. doi: 10.1158/1078-0432.CCR-18-3470. Epub 2019 Mar 19.

PMID:
30890552
4.

Where do we currently stand with T-cell prolymphocytic leukemia?

Khot A.

Leuk Lymphoma. 2019 Mar;60(3):563-565. doi: 10.1080/10428194.2018.1551543. Epub 2019 Jan 22. No abstract available.

PMID:
30668215
5.

Measurement and Quantitative Characterization of Whole-Body Pharmacokinetics of Exogenously Administered T Cells in Mice.

Khot A, Matsueda S, Thomas VA, Koya RC, Shah DK.

J Pharmacol Exp Ther. 2019 Mar;368(3):503-513. doi: 10.1124/jpet.118.252858. Epub 2019 Jan 8.

PMID:
30622170
6.

Target-Mediated Drug Disposition Model for Bispecific Antibodies: Properties, Approximation, and Optimal Dosing Strategy.

Schropp J, Khot A, Shah DK, Koch G.

CPT Pharmacometrics Syst Pharmacol. 2019 Mar;8(3):177-187. doi: 10.1002/psp4.12369. Epub 2019 Jan 8.

7.

Mogamulizumab versus vorinostat in previously treated cutaneous T-cell lymphoma (MAVORIC): an international, open-label, randomised, controlled phase 3 trial.

Kim YH, Bagot M, Pinter-Brown L, Rook AH, Porcu P, Horwitz SM, Whittaker S, Tokura Y, Vermeer M, Zinzani PL, Sokol L, Morris S, Kim EJ, Ortiz-Romero PL, Eradat H, Scarisbrick J, Tsianakas A, Elmets C, Dalle S, Fisher DC, Halwani A, Poligone B, Greer J, Fierro MT, Khot A, Moskowitz AJ, Musiek A, Shustov A, Pro B, Geskin LJ, Dwyer K, Moriya J, Leoni M, Humphrey JS, Hudgens S, Grebennik DO, Tobinai K, Duvic M; MAVORIC Investigators.

Lancet Oncol. 2018 Sep;19(9):1192-1204. doi: 10.1016/S1470-2045(18)30379-6. Epub 2018 Aug 9. Erratum in: Lancet Oncol. 2018 Nov;19(11):e581.

PMID:
30100375
8.

Classifying Adverse Events Following Lower Limb Orthopaedic Surgery in Children With Cerebral Palsy: Reliability of the Modified Clavien-Dindo System.

Zhou L, Willoughby K, Strobel N, Thomason P, Gallagher C, Harambasic M, Khot A, Graham HK.

J Pediatr Orthop. 2018 Nov/Dec;38(10):e604-e609. doi: 10.1097/BPO.0000000000001233.

9.

Symptomatic hallux valgus and dorsal bunion in adolescents with cerebral palsy: clinical and biomechanical factors.

van de Velde SK, Cashin M, Johari R, Blackshaw R, Khot A, Graham HK.

Dev Med Child Neurol. 2018 Jun;60(6):624-628. doi: 10.1111/dmcn.13724. Epub 2018 Mar 8.

10.

A phase 1 clinical trial evaluating marizomib, pomalidomide and low-dose dexamethasone in relapsed and refractory multiple myeloma (NPI-0052-107): final study results.

Spencer A, Harrison S, Zonder J, Badros A, Laubach J, Bergin K, Khot A, Zimmerman T, Chauhan D, Levin N, MacLaren A, Reich SD, Trikha M, Richardson P.

Br J Haematol. 2018 Jan;180(1):41-51. doi: 10.1111/bjh.14987. Epub 2017 Oct 26.

PMID:
29076150
11.

Development of a Translational Physiologically Based Pharmacokinetic Model for Antibody-Drug Conjugates: a Case Study with T-DM1.

Khot A, Tibbitts J, Rock D, Shah DK.

AAPS J. 2017 Nov;19(6):1715-1734. doi: 10.1208/s12248-017-0131-3. Epub 2017 Aug 14.

12.

Comprehensive genomic characterization dissects the complex biology of a case of synchronous Burkitt lymphoma and myeloid malignancy with shared hematopoietic ancestry.

Ryland GL, Jones K, McBean M, Khot A, Seymour JF, Blombery P.

Leuk Lymphoma. 2018 Apr;59(4):992-995. doi: 10.1080/10428194.2017.1361029. Epub 2017 Aug 9. No abstract available.

PMID:
28792266
13.

Proximal femoral osteotomy in children with cerebral palsy: the perspective of the trainee.

Zhou L, Camp M, Gahukamble A, Willoughby KL, Harambasic M, Molesworth C, Khot A, Graham HK.

J Child Orthop. 2017;11(1):6-14. doi: 10.1302/1863-2548-11-160226.

14.

Comparative Effectiveness Research: The Impact of Biologic Agents in Ethnic Minorities With Metastatic Colorectal Cancer.

Goel S, Negassa A, Khot A, Goyal D, Guo S, Nandikolla A, Bakirhan K, Polineni R, Shah U, Chaudhary I, Ghalib MH, Rajdev L, Kaubisch A, Chuy J, Aparo S.

Clin Colorectal Cancer. 2017 Dec;16(4):286-292. doi: 10.1016/j.clcc.2017.03.004. Epub 2017 Mar 14.

PMID:
28412139
15.

Antianginal Efficacy and Tolerability of Ranolazine as an Add-on Drug to Concomitant Medications Primarily Metoprolol in Chronic Stable Angina Patients: A Prospective, Open-Label Study.

Khot AM, Anuradha HV, Prakash VS, Shivamurathy MC.

J Pharmacol Pharmacother. 2017 Jan-Mar;8(1):21-27. doi: 10.4103/jpp.JPP_168_16.

16.

Durable clinical remission induced by romidepsin for chemotherapy-refractory peripheral T-cell lymphoma with central nervous system involvement.

Chan KL, van der Weyden C, Khoo C, Lade S, Blombery P, Westerman D, Khot A, Melo B, Johnstone RW, Prince HM, Dickinson M.

Leuk Lymphoma. 2017 Apr;58(4):996-998. doi: 10.1080/10428194.2016.1222375. Epub 2016 Aug 25. No abstract available.

PMID:
27558082
17.

Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling.

Quin J, Chan KT, Devlin JR, Cameron DP, Diesch J, Cullinane C, Ahern J, Khot A, Hein N, George AJ, Hannan KM, Poortinga G, Sheppard KE, Khanna KK, Johnstone RW, Drygin D, McArthur GA, Pearson RB, Sanij E, Hannan RD.

Oncotarget. 2016 Aug 2;7(31):49800-49818. doi: 10.18632/oncotarget.10452.

18.

Whole exome sequencing reveals activating JAK1 and STAT3 mutations in breast implant-associated anaplastic large cell lymphoma anaplastic large cell lymphoma.

Blombery P, Thompson ER, Jones K, Arnau GM, Lade S, Markham JF, Li J, Deva A, Johnstone RW, Khot A, Prince HM, Westerman D.

Haematologica. 2016 Sep;101(9):e387-90. doi: 10.3324/haematol.2016.146118. Epub 2016 May 19. No abstract available.

19.

Evolution of Antibody-Drug Conjugate Tumor Disposition Model to Predict Preclinical Tumor Pharmacokinetics of Trastuzumab-Emtansine (T-DM1).

Singh AP, Maass KF, Betts AM, Wittrup KD, Kulkarni C, King LE, Khot A, Shah DK.

AAPS J. 2016 Jul;18(4):861-75. doi: 10.1208/s12248-016-9904-3. Epub 2016 Mar 30.

20.

Musculoskeletal Evaluation of Children with Cerebral Palsy.

Johari R, Maheshwari S, Thomason P, Khot A.

Indian J Pediatr. 2016 Nov;83(11):1280-1288. Epub 2016 Jan 23. Review.

PMID:
26801500
21.

High prevalence of vitamin D deficiency in 2-17 year olds presenting with acute fractures in southern Australia.

Kwon DH, Krieser D, Harris C, Khot A, Ebeling PR, Rodda CP.

Bone Rep. 2016 May 28;5:153-157. doi: 10.1016/j.bonr.2016.05.007. eCollection 2016 Dec.

22.

The radiological assessment of pelvic obliquity in cerebral palsy and the impact on hip development.

Heidt C, Hollander K, Wawrzuta J, Molesworth C, Willoughby K, Thomason P, Khot A, Graham HK.

Bone Joint J. 2015 Oct;97-B(10):1435-40. doi: 10.1302/0301-620X.97B10.35390.

PMID:
26430022
23.

Integration of bioanalytical measurements using PK-PD modeling and simulation: implications for antibody-drug conjugate development.

Khot A, Sharma S, Shah DK.

Bioanalysis. 2015;7(13):1633-48. doi: 10.4155/bio.15.85. Review.

PMID:
26226312
24.

The transverse Vulpius gastrocsoleus recession for equinus gait in children with cerebral palsy.

Tinney A, Thomason P, Sangeux M, Khot A, Graham HK.

Bone Joint J. 2015 Apr;97-B(4):564-71. doi: 10.1302/0301-620X.97B4.34887.

PMID:
25820899
25.

Cannulated, locking blade plates for proximal femoral osteotomy in children and adolescents.

Zhou L, Camp M, Gahukamble A, Khot A, Graham HK.

J Child Orthop. 2015 Apr;9(2):121-7. doi: 10.1007/s11832-015-0649-9. Epub 2015 Mar 24.

26.

Lack of durable disease control with chemotherapy for mycosis fungoides and Sézary syndrome: a comparative study of systemic therapy.

Hughes CF, Khot A, McCormack C, Lade S, Westerman DA, Twigger R, Buelens O, Newland K, Tam C, Dickinson M, Ryan G, Ritchie D, Wood C, Prince HM.

Blood. 2015 Jan 1;125(1):71-81. doi: 10.1182/blood-2014-07-588236. Epub 2014 Oct 21.

27.

Ibrutinib inhibits collagen-mediated but not ADP-mediated platelet aggregation.

Kamel S, Horton L, Ysebaert L, Levade M, Burbury K, Tan S, Cole-Sinclair M, Reynolds J, Filshie R, Schischka S, Khot A, Sandhu S, Keating MJ, Nandurkar H, Tam CS.

Leukemia. 2015 Apr;29(4):783-7. doi: 10.1038/leu.2014.247. Epub 2014 Aug 20.

PMID:
25138588
28.

Abdominal tuberculosis masquerading as intestinal lymphangiectasia.

Khot A, Somani P, Thiruvengadam N, Gharat A, Rathi P.

Trop Gastroenterol. 2013 Oct-Dec;34(4):285-6. No abstract available.

PMID:
25046900
29.

Long-Term Disease Control in a Patient With Recurrent Bone-Only Oligometastatic Nasopharyngeal Carcinoma.

Khot A, Love C, Garg MK, Haigentz M Jr.

J Clin Oncol. 2016 Feb 1;34(4):e25-6. doi: 10.1200/JCO.2013.51.3549. Epub 2014 Jun 9. No abstract available.

PMID:
24912898
30.

Gastrocsoleus recession techniques: an anatomical and biomechanical study in human cadavers.

Tinney A, Khot A, Eizenberg N, Wolfe R, Graham HK.

Bone Joint J. 2014 Jun;96-B(6):778-82. doi: 10.1302/0301-620X.96B6.33700.

PMID:
24891578
31.

Romidepsin for cutaneous T-cell lymphoma.

Prince HM, Dickinson M, Khot A.

Future Oncol. 2013 Dec;9(12):1819-27. doi: 10.2217/fon.13.220.

PMID:
24295412
32.

Prognostic factors in acute-on-chronic liver failure: a prospective study from western India.

Khot AA, Somani P, Rathi P, Amarapurkar A.

Indian J Gastroenterol. 2014 Mar;33(2):119-24. doi: 10.1007/s12664-013-0409-z.

PMID:
24122317
33.

Uncomplicated spontaneous rupture of pancreatic pseudocyst into stomach: A case report.

Somani PO, Jain SS, Shah DK, Khot AA, Rathi PM.

World J Gastrointest Endosc. 2013 Sep 16;5(9):461-4. doi: 10.4253/wjge.v5.i9.461.

34.

Romidepsin for peripheral T-cell lymphoma.

Khot A, Dickinson M, Prince HM.

Expert Rev Hematol. 2013 Aug;6(4):351-9. doi: 10.1586/17474086.2013.814833. Review.

PMID:
23991922
35.

Myeloma and pregnancy: strange bedfellows?

Khot AS, Prince HM, Harrison SJ, Seymour JF.

Leuk Lymphoma. 2014 Apr;55(4):966-8. doi: 10.3109/10428194.2013.837163. Epub 2013 Sep 9. No abstract available.

PMID:
23964646
36.

Persistence and efficacy of second generation CAR T cell against the LeY antigen in acute myeloid leukemia.

Ritchie DS, Neeson PJ, Khot A, Peinert S, Tai T, Tainton K, Chen K, Shin M, Wall DM, Hönemann D, Gambell P, Westerman DA, Haurat J, Westwood JA, Scott AM, Kravets L, Dickinson M, Trapani JA, Smyth MJ, Darcy PK, Kershaw MH, Prince HM.

Mol Ther. 2013 Nov;21(11):2122-9. doi: 10.1038/mt.2013.154. Epub 2013 Jul 8.

37.

Panobinostat in lymphoid and myeloid malignancies.

Khot A, Dickinson M, Prince HM.

Expert Opin Investig Drugs. 2013 Sep;22(9):1211-23. doi: 10.1517/13543784.2013.815165. Epub 2013 Jul 3. Review.

PMID:
23826641
38.

A messenger at the door: cytomegalovirus retinitis in myeloma patients with progressive disease.

Teh BW, Khot AS, Harrison SJ, Prince HM, Slavin MA.

Transpl Infect Dis. 2013 Aug;15(4):E134-8. doi: 10.1111/tid.12106. Epub 2013 Jun 23.

PMID:
23790037
39.

Subtalar fusion for pes valgus in cerebral palsy: results of a modified technique in the setting of single event multilevel surgery.

Shore BJ, Smith KR, Riazi A, Symons SB, Khot A, Graham K.

J Pediatr Orthop. 2013 Jun;33(4):431-8. doi: 10.1097/BPO.0b013e31827d0afa.

PMID:
23653034
40.

Acute kidney injury requiring dialysis following carmustine and etoposide during autologous stem cell transplantation.

Li J, Khot A, Burbury K.

Chemotherapy. 2012;58(5):349-51. doi: 10.1159/000343661. Epub 2012 Nov 17.

PMID:
23171711
41.

A risk-adapted protocol for delayed administration of filgrastim after high-dose chemotherapy and autologous stem cell transplantation.

Khot A, Dickinson M, Stokes K, Harrison S, Burbury K, Fleming S, Wall D, Gambell P, Prince HM, Seymour JF, Ritchie D.

Clin Lymphoma Myeloma Leuk. 2013 Feb;13(1):42-7. doi: 10.1016/j.clml.2012.09.017. Epub 2012 Nov 10.

PMID:
23146384
42.

Pseudomelanosis Duodeni of Undetermined Etiology.

Jain SS, Shah DK, Khot AA, T NR, Gharat AR, Rathi PM.

Gastroenterology Res. 2012 Aug;5(4):171-173. Epub 2012 Jul 20.

43.

Strengthening the health system to better confront noncommunicable diseases in India.

Duran A, Khot A.

Indian J Community Med. 2011 Dec;36(Suppl 1):S32-7. doi: 10.4103/0970-0218.94706.

44.

M(yeloma)IXing up T maintenance.

Harrison SJ, Khot A.

Blood. 2012 Jan 5;119(1):1-2. doi: 10.1182/blood-2011-11-388181. No abstract available.

45.

Clinical characteristics and outcomes of patients with acute lung injury and ARDS.

Bhadade RR, de Souza RA, Harde MJ, Khot A.

J Postgrad Med. 2011 Oct-Dec;57(4):286-90. doi: 10.4103/0022-3859.90077.

46.

Alemtuzumab therapy in T-cell prolymphocytic leukemia: comparing efficacy in a series treated intravenously and a study piloting the subcutaneous route.

Dearden CE, Khot A, Else M, Hamblin M, Grand E, Roy A, Hewamana S, Matutes E, Catovsky D.

Blood. 2011 Nov 24;118(22):5799-802. doi: 10.1182/blood-2011-08-372854. Epub 2011 Sep 26.

47.

Bortezomib, cyclophosphamide, and dexamethasone: highly effective for rapid reversal of myeloma-associated hyperammonemic encephalopathy.

Howman R, Thakerer A, Pitman M, Ding N, Thompson PA, Khot A, Harrison SJ.

Leuk Lymphoma. 2010 Dec;51(12):2299-302. doi: 10.3109/10428194.2010.518654. Epub 2010 Oct 7. No abstract available.

PMID:
20929329
48.

Adductor release and chemodenervation in children with cerebral palsy: a pilot study in 16 children.

Khot A, Sloan S, Desai S, Harvey A, Wolfe R, Graham HK.

J Child Orthop. 2008 Aug;2(4):293-9. doi: 10.1007/s11832-008-0105-1. Epub 2008 Jun 7.

49.

T-cell prolymphocytic leukemia.

Khot A, Dearden C.

Expert Rev Anticancer Ther. 2009 Mar;9(3):365-71. doi: 10.1586/14737140.9.3.365. Review.

PMID:
19275513
50.

A novel assay reveals the blockade of esterases by piperonyl butoxide.

Khot AC, Bingham G, Field LM, Moores GD.

Pest Manag Sci. 2008 Nov;64(11):1139-42. doi: 10.1002/ps.1603.

PMID:
18481337

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