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Items: 1 to 50 of 122

1.

Microbiome swings with repeated insults.

Rashidi A, Maeser D, Kaiser T, Ebadi M, Rehman TU, Holtan SG, Weisdorf DJ, Khoruts A, Staley C.

Br J Haematol. 2020 Feb 10. doi: 10.1111/bjh.16509. [Epub ahead of print] No abstract available.

PMID:
32043276
2.

Microbiota changes and Intestinal Microbiota Transplantation in Liver Diseases and Cirrhosis.

Bajaj JS, Khoruts A.

J Hepatol. 2020 Jan 28. pii: S0168-8278(20)30058-1. doi: 10.1016/j.jhep.2020.01.017. [Epub ahead of print]

PMID:
32004593
3.

Interactions between the gut microbiome and host gene regulation in cystic fibrosis.

Dayama G, Priya S, Niccum DE, Khoruts A, Blekhman R.

Genome Med. 2020 Jan 28;12(1):12. doi: 10.1186/s13073-020-0710-2.

4.

The Impact of Regulatory Policies on the Future of Fecal Microbiota Transplantation.

Khoruts A, Hoffmann DE, Palumbo FB.

J Law Med Ethics. 2019 Dec;47(4):482-504. doi: 10.1177/1073110519897726.

PMID:
31957587
5.

Gut dysbiosis during antileukemia chemotherapy versus allogeneic hematopoietic cell transplantation.

Rashidi A, Kaiser T, Graiziger C, Holtan SG, Rehman TU, Weisdorf DJ, Dunny GM, Khoruts A, Staley C.

Cancer. 2019 Dec 24. doi: 10.1002/cncr.32641. [Epub ahead of print]

PMID:
31873965
6.

Levaquin Gets a Pass.

Rashidi A, Kaiser T, Holtan SG, Rehman TU, Weisdorf DJ, Khoruts A, Staley C.

Biol Blood Marrow Transplant. 2019 Dec 20. pii: S1083-8791(19)31651-9. doi: 10.1016/j.bbmt.2019.12.722. [Epub ahead of print]

PMID:
31870930
7.

Microbiota transplant therapy and autism: lessons for the clinic.

Adams JB, Borody TJ, Kang DW, Khoruts A, Krajmalnik-Brown R, Sadowsky MJ.

Expert Rev Gastroenterol Hepatol. 2019 Nov;13(11):1033-1037. doi: 10.1080/17474124.2019.1687293. Epub 2019 Nov 7.

PMID:
31665947
8.

Vancomycin-resistance gene cluster, vanC, in the gut microbiome of acute leukemia patients undergoing intensive chemotherapy.

Rashidi A, Zhu Z, Kaiser T, Manias DA, Holtan SG, Rehman TU, Weisdorf DJ, Khoruts A, Dunny GM, Staley C.

PLoS One. 2019 Oct 10;14(10):e0223890. doi: 10.1371/journal.pone.0223890. eCollection 2019.

9.

Can intestinal microbiota and circulating microbial products contribute to pulmonary arterial hypertension?

Thenappan T, Khoruts A, Chen Y, Weir EK.

Am J Physiol Heart Circ Physiol. 2019 Nov 1;317(5):H1093-H1101. doi: 10.1152/ajpheart.00416.2019. Epub 2019 Sep 6.

PMID:
31490732
10.

Specific gut microbiota changes heralding bloodstream infection and neutropenic fever during intensive chemotherapy.

Rashidi A, Kaiser T, Graiziger C, Holtan SG, Rehman TU, Weisdorf DJ, Khoruts A, Staley C.

Leukemia. 2020 Jan;34(1):312-316. doi: 10.1038/s41375-019-0547-0. Epub 2019 Aug 22. No abstract available.

PMID:
31439944
11.

Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization.

Huggins MA, Sjaastad FV, Pierson M, Kucaba TA, Swanson W, Staley C, Weingarden AR, Jensen IJ, Danahy DB, Badovinac VP, Jameson SC, Vezys V, Masopust D, Khoruts A, Griffith TS, Hamilton SE.

Cell Rep. 2019 Aug 13;28(7):1729-1743.e5. doi: 10.1016/j.celrep.2019.07.028.

12.

Stress responses, M2 macrophages, and a distinct microbial signature in fatal intestinal acute graft-versus-host disease.

Holtan SG, Shabaneh A, Betts BC, Rashidi A, MacMillan ML, Ustun C, Amin K, Vaughn BP, Howard J, Khoruts A, Arora M, DeFor TE, Johnson D, Blazar BR, Weisdorf DJ, Wang J.

JCI Insight. 2019 Aug 8;5. pii: 129762. doi: 10.1172/jci.insight.129762.

13.
14.

Durable Long-Term Bacterial Engraftment following Encapsulated Fecal Microbiota Transplantation To Treat Clostridium difficile Infection.

Staley C, Kaiser T, Vaughn BP, Graiziger C, Hamilton MJ, Kabage AJ, Khoruts A, Sadowsky MJ.

mBio. 2019 Jul 23;10(4). pii: e01586-19. doi: 10.1128/mBio.01586-19.

15.

7-Methylation of Chenodeoxycholic Acid Derivatives Yields a Substantial Increase in TGR5 Receptor Potency.

Nakhi A, McDermott CM, Stoltz KL, John K, Hawkinson JE, Ambrose EA, Khoruts A, Sadowsky MJ, Dosa PI.

J Med Chem. 2019 Jul 25;62(14):6824-6830. doi: 10.1021/acs.jmedchem.9b00770. Epub 2019 Jul 3.

PMID:
31268316
16.

Fecal Microbiota Transplant: A Rose by Any Other Name.

Khoruts A, Brandt LJ.

Am J Gastroenterol. 2019 Jul;114(7):1176. doi: 10.14309/ajg.0000000000000286. No abstract available.

PMID:
31205129
17.

Antibiotic-induced Disruption of Intestinal Microbiota Contributes to Failure of Vertical Sleeve Gastrectomy.

Jahansouz C, Staley C, Kizy S, Xu H, Hertzel AV, Coryell J, Singroy S, Hamilton M, DuRand M, Bernlohr DA, Sadowsky MJ, Khoruts A, Ikramuddin S.

Ann Surg. 2019 Jun;269(6):1092-1100. doi: 10.1097/SLA.0000000000002729.

PMID:
31082907
18.

Letter to the Editor.

Khoruts A, Sadowsky MJ.

Clin Infect Dis. 2019 Nov 27;69(12):2232-2233. doi: 10.1093/cid/ciz366. No abstract available.

PMID:
31051514
19.

Dietary Factors in Sulfur Metabolism and Pathogenesis of Ulcerative Colitis.

Teigen LM, Geng Z, Sadowsky MJ, Vaughn BP, Hamilton MJ, Khoruts A.

Nutrients. 2019 Apr 25;11(4). pii: E931. doi: 10.3390/nu11040931. Review.

20.

Cost-effectiveness of Treatment Regimens for Clostridioides difficile Infection: An Evaluation of the 2018 Infectious Diseases Society of America Guidelines.

Rajasingham R, Enns EA, Khoruts A, Vaughn BP.

Clin Infect Dis. 2020 Feb 14;70(5):754-762. doi: 10.1093/cid/ciz318.

PMID:
31001619
21.

Dysbiosis patterns during re-induction/salvage versus induction chemotherapy for acute leukemia.

Rashidi A, Kaiser T, Shields-Cutler R, Graiziger C, Holtan SG, Rehman TU, Wasko J, Weisdorf DJ, Dunny G, Khoruts A, Staley C.

Sci Rep. 2019 Apr 15;9(1):6083. doi: 10.1038/s41598-019-42652-6.

22.

Influence of short-term changes in dietary sulfur on the relative abundances of intestinal sulfate-reducing bacteria.

Dostal Webster A, Staley C, Hamilton MJ, Huang M, Fryxell K, Erickson R, Kabage AJ, Sadowsky MJ, Khoruts A.

Gut Microbes. 2019;10(4):447-457. doi: 10.1080/19490976.2018.1559682. Epub 2019 Feb 27.

PMID:
30810441
23.

A pilot study of fecal bile acid and microbiota profiles in inflammatory bowel disease and primary sclerosing cholangitis.

Vaughn BP, Kaiser T, Staley C, Hamilton MJ, Reich J, Graiziger C, Singroy S, Kabage AJ, Sadowsky MJ, Khoruts A.

Clin Exp Gastroenterol. 2019 Jan 10;12:9-19. doi: 10.2147/CEG.S186097. eCollection 2019.

24.

Pre-transplant recovery of microbiome diversity without recovery of the original microbiome.

Rashidi A, Kaiser T, Holtan SG, Weisdorf DJ, Khoruts A, Staley C.

Bone Marrow Transplant. 2019 Jul;54(7):1115-1117. doi: 10.1038/s41409-018-0414-z. Epub 2018 Nov 29. No abstract available.

PMID:
30498199
25.

Pretransplant Serum Citrulline Predicts Acute Graft-versus-Host Disease.

Rashidi A, Shanley R, Holtan SG, MacMillan ML, Blazar BR, Khoruts A, Weisdorf DJ.

Biol Blood Marrow Transplant. 2018 Nov;24(11):2190-2196. doi: 10.1016/j.bbmt.2018.06.036. Epub 2018 Jul 7.

26.

Amphiregulin in intestinal acute graft-versus-host disease: a possible diagnostic and prognostic aid.

Amin K, Yaqoob U, Schultz B, Vaughn BP, Khoruts A, Howard JR, DeFor TE, Forster C, Meyer C, Gandhi I, Weisdorf DJ, Rashidi A, MacMillan ML, Blazar BR, Panoskaltsis-Mortari A, Holtan SG.

Mod Pathol. 2019 Apr;32(4):560-567. doi: 10.1038/s41379-018-0170-z. Epub 2018 Nov 13.

PMID:
30425334
27.

Targeting the microbiome: from probiotics to fecal microbiota transplantation.

Khoruts A.

Genome Med. 2018 Oct 30;10(1):80. doi: 10.1186/s13073-018-0592-8. Review.

28.

Clinician Guide to Microbiome Testing.

Staley C, Kaiser T, Khoruts A.

Dig Dis Sci. 2018 Dec;63(12):3167-3177. doi: 10.1007/s10620-018-5299-6. Epub 2018 Sep 28. Review.

PMID:
30267172
29.

Predicting recurrence of Clostridium difficile infection following encapsulated fecal microbiota transplantation.

Staley C, Kaiser T, Vaughn BP, Graiziger CT, Hamilton MJ, Rehman TU, Song K, Khoruts A, Sadowsky MJ.

Microbiome. 2018 Sep 18;6(1):166. doi: 10.1186/s40168-018-0549-6.

30.

Gastrointestinal cancers in patients with cystic fibrosis.

Maisonneuve P, Lowenfels AB, Hadjiliadis D, Khoruts A, Marshall BC.

Lancet Oncol. 2018 Aug;19(8):e368. doi: 10.1016/S1470-2045(18)30485-6. No abstract available.

PMID:
30102218
31.

CLOUD: a non-parametric detection test for microbiome outliers.

Montassier E, Al-Ghalith GA, Hillmann B, Viskocil K, Kabage AJ, McKinlay CE, Sadowsky MJ, Khoruts A, Knights D.

Microbiome. 2018 Aug 6;6(1):137. doi: 10.1186/s40168-018-0514-4.

32.

Fecal Microbiota Transplantation: Current Status in Treatment of GI and Liver Disease.

Vaughn BP, Rank KM, Khoruts A.

Clin Gastroenterol Hepatol. 2019 Jan;17(2):353-361. doi: 10.1016/j.cgh.2018.07.026. Epub 2018 Jul 25. Review.

PMID:
30055267
33.

Colorectal cancer mutational profiles correlate with defined microbial communities in the tumor microenvironment.

Burns MB, Montassier E, Abrahante J, Priya S, Niccum DE, Khoruts A, Starr TK, Knights D, Blekhman R.

PLoS Genet. 2018 Jun 20;14(6):e1007376. doi: 10.1371/journal.pgen.1007376. eCollection 2018 Jun.

34.

Reply.

Hadjiliadis D, Khoruts A, Zauber AG, Hempstead SE, Maisonneuve P, Lowenfels AB.

Gastroenterology. 2018 Jun;154(8):2283-2284. doi: 10.1053/j.gastro.2018.05.017. Epub 2018 May 8. No abstract available.

PMID:
29750906
35.

Is fecal microbiota transplantation a temporary patch for treatment of Clostridium difficile infection or a new frontier of therapeutics?

Khoruts A.

Expert Rev Gastroenterol Hepatol. 2018 May;12(5):435-438. doi: 10.1080/17474124.2018.1465818. Epub 2018 Apr 20. No abstract available.

PMID:
29667436
36.

Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation.

Smillie CS, Sauk J, Gevers D, Friedman J, Sung J, Youngster I, Hohmann EL, Staley C, Khoruts A, Sadowsky MJ, Allegretti JR, Smith MB, Xavier RJ, Alm EJ.

Cell Host Microbe. 2018 Feb 14;23(2):229-240.e5. doi: 10.1016/j.chom.2018.01.003.

37.

Cystic Fibrosis Colorectal Cancer Screening Consensus Recommendations.

Hadjiliadis D, Khoruts A, Zauber AG, Hempstead SE, Maisonneuve P, Lowenfels AB; Cystic Fibrosis Colorectal Cancer Screening Task Force.

Gastroenterology. 2018 Feb;154(3):736-745.e14. doi: 10.1053/j.gastro.2017.12.012. Epub 2017 Dec 29.

PMID:
29289528
38.

Contemporary Applications of Fecal Microbiota Transplantation to Treat Intestinal Diseases in Humans.

Staley C, Khoruts A, Sadowsky MJ.

Arch Med Res. 2017 Nov;48(8):766-773. doi: 10.1016/j.arcmed.2017.11.006. Epub 2017 Nov 26. Review.

PMID:
29183720
39.

Functional Genomics of Host-Microbiome Interactions in Humans.

Luca F, Kupfer SS, Knights D, Khoruts A, Blekhman R.

Trends Genet. 2018 Jan;34(1):30-40. doi: 10.1016/j.tig.2017.10.001. Epub 2017 Oct 26. Review.

40.

Defining total-body AIDS-virus burden with implications for curative strategies.

Estes JD, Kityo C, Ssali F, Swainson L, Makamdop KN, Del Prete GQ, Deeks SG, Luciw PA, Chipman JG, Beilman GJ, Hoskuldsson T, Khoruts A, Anderson J, Deleage C, Jasurda J, Schmidt TE, Hafertepe M, Callisto SP, Pearson H, Reimann T, Schuster J, Schoephoerster J, Southern P, Perkey K, Shang L, Wietgrefe SW, Fletcher CV, Lifson JD, Douek DC, McCune JM, Haase AT, Schacker TW.

Nat Med. 2017 Nov;23(11):1271-1276. doi: 10.1038/nm.4411. Epub 2017 Oct 2.

41.

Stable engraftment of human microbiota into mice with a single oral gavage following antibiotic conditioning.

Staley C, Kaiser T, Beura LK, Hamilton MJ, Weingarden AR, Bobr A, Kang J, Masopust D, Sadowsky MJ, Khoruts A.

Microbiome. 2017 Aug 1;5(1):87. doi: 10.1186/s40168-017-0306-2.

42.

Changes in microbial ecology after fecal microbiota transplantation for recurrent C. difficile infection affected by underlying inflammatory bowel disease.

Khanna S, Vazquez-Baeza Y, González A, Weiss S, Schmidt B, Muñiz-Pedrogo DA, Rainey JF 3rd, Kammer P, Nelson H, Sadowsky M, Khoruts A, Farrugia SL, Knight R, Pardi DS, Kashyap PC.

Microbiome. 2017 May 15;5(1):55. doi: 10.1186/s40168-017-0269-3.

43.

Synthesis and Biological Evaluation of Bile Acid Analogues Inhibitory to Clostridium difficile Spore Germination.

Stoltz KL, Erickson R, Staley C, Weingarden AR, Romens E, Steer CJ, Khoruts A, Sadowsky MJ, Dosa PI.

J Med Chem. 2017 Apr 27;60(8):3451-3471. doi: 10.1021/acs.jmedchem.7b00295. Epub 2017 Apr 12.

44.

Fecal microbiota transplantation-early steps on a long journey ahead.

Khoruts A.

Gut Microbes. 2017 May 4;8(3):199-204. doi: 10.1080/19490976.2017.1316447. Epub 2017 Apr 10. No abstract available.

45.

Community dynamics drive punctuated engraftment of the fecal microbiome following transplantation using freeze-dried, encapsulated fecal microbiota.

Staley C, Vaughn BP, Graiziger CT, Singroy S, Hamilton MJ, Yao D, Chen C, Khoruts A, Sadowsky MJ.

Gut Microbes. 2017 May 4;8(3):276-288. doi: 10.1080/19490976.2017.1299310. Epub 2017 Feb 28.

46.

Sleeve gastrectomy drives persistent shifts in the gut microbiome.

Jahansouz C, Staley C, Bernlohr DA, Sadowsky MJ, Khoruts A, Ikramuddin S.

Surg Obes Relat Dis. 2017 Jun;13(6):916-924. doi: 10.1016/j.soard.2017.01.003. Epub 2017 Jan 4.

PMID:
28279578
47.

Infection Followed by Graft-versus-Host Disease: Pathogenic Role of Antibiotics.

Rashidi A, Khoruts A, Weisdorf DJ.

Biol Blood Marrow Transplant. 2017 Jun;23(6):1038-1039. doi: 10.1016/j.bbmt.2017.02.016. Epub 2017 Feb 28. No abstract available.

48.

Successful Resolution of Recurrent Clostridium difficile Infection using Freeze-Dried, Encapsulated Fecal Microbiota; Pragmatic Cohort Study.

Staley C, Hamilton MJ, Vaughn BP, Graiziger CT, Newman KM, Kabage AJ, Sadowsky MJ, Khoruts A.

Am J Gastroenterol. 2017 Jun;112(6):940-947. doi: 10.1038/ajg.2017.6. Epub 2017 Feb 14.

49.

Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study.

Kang DW, Adams JB, Gregory AC, Borody T, Chittick L, Fasano A, Khoruts A, Geis E, Maldonado J, McDonough-Means S, Pollard EL, Roux S, Sadowsky MJ, Lipson KS, Sullivan MB, Caporaso JG, Krajmalnik-Brown R.

Microbiome. 2017 Jan 23;5(1):10. doi: 10.1186/s40168-016-0225-7.

50.

Treatment of recurrent Clostridium difficile infection using fecal microbiota transplantation in patients with inflammatory bowel disease.

Newman KM, Rank KM, Vaughn BP, Khoruts A.

Gut Microbes. 2017 May 4;8(3):303-309. doi: 10.1080/19490976.2017.1279377. Epub 2017 Jan 19.

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