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Items: 1 to 50 of 250

1.

Peri-Infarct Upregulation of the Oxytocin Receptor in Vascular Dementia.

McKay EC, Beck JS, Khoo SK, Dykema KJ, Cottingham SL, Winn ME, Paulson HL, Lieberman AP, Counts SE.

J Neuropathol Exp Neurol. 2019 May 1;78(5):436-452. doi: 10.1093/jnen/nlz023.

PMID:
30990880
2.

Development of highly potent glucocorticoids for steroid-resistant severe asthma.

He Y, Shi J, Nguyen QT, You E, Liu H, Ren X, Wu Z, Li J, Qiu W, Khoo SK, Yang T, Yi W, Sun F, Xi Z, Huang X, Melcher K, Min B, Xu HE.

Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6932-6937. doi: 10.1073/pnas.1816734116. Epub 2019 Mar 20.

PMID:
30894497
3.

Upper Airway Cell Transcriptomics Identify a Major New Immunological Phenotype with Strong Clinical Correlates in Young Children with Acute Wheezing.

Khoo SK, Read J, Franks K, Zhang G, Bizzintino J, Coleman L, McCrae C, Öberg L, Troy NM, Prastanti F, Everard J, Oo S, Borland ML, Maciewicz RA, Le Souëf PN, Laing IA, Bosco A.

J Immunol. 2019 Mar 15;202(6):1845-1858. doi: 10.4049/jimmunol.1800178. Epub 2019 Feb 11.

PMID:
30745463
4.

Cord Blood IL-12 Confers Protection to Clinical Malaria in Early Childhood Life.

Song Y, Aguilar R, Guo J, Manaca MN, Nhabomba A, Berthoud TK, Khoo SK, Wiertsema S, Barbosa A, Quintó L, Laing IA, Mayor A, Guinovart C, Alonso PL, LeSouëf PN, Dobaño C, Zhang GB.

Sci Rep. 2018 Jul 18;8(1):10860. doi: 10.1038/s41598-018-29179-y.

5.

Rhinovirus is the most common virus and rhinovirus-C is the most common species in paediatric intensive care respiratory admissions.

Cox DW, Khoo SK, Zhang G, Lindsay K, Keil AD, Knight G, Gern JE, Laing IA, Bizzintino J, Le Souëf PN.

Eur Respir J. 2018 Aug 9;52(2). pii: 1800207. doi: 10.1183/13993003.00207-2018. Print 2018 Aug. No abstract available.

PMID:
29976655
6.

Airway Interleukin-33 and type 2 cytokines in adult patients with acute asthma.

Poulsen NN, Bjerregaard A, Khoo SK, Laing IA, Le Souëf P, Backer V, Rapley L, Cohen SE, Barrett L, Thompson P, Baltic S, Porsbjerg C.

Respir Med. 2018 Jul;140:50-56. doi: 10.1016/j.rmed.2018.05.016. Epub 2018 May 19.

PMID:
29957280
7.

Prospective Assessment of Rhinovirus Symptoms and Species Recurrence in Children With and Without an Acute Wheezing Exacerbation.

Lethbridge R, Prastanti F, Robertson C, Oo S, Khoo SK, Le Souëf PN, Laing IA.

Viral Immunol. 2018 May;31(4):299-305. doi: 10.1089/vim.2017.0152. Epub 2018 Feb 15.

PMID:
29446705
8.

Dual responses of CD14 methylation to distinct environments: a role in asthma and allergy.

Song Y, Khoo SK, Lee KH, Mäkelä M, Haahtela T, LeSouëf P, Zhang GB.

Eur Respir J. 2017 Dec 14;50(6). pii: 1701228. doi: 10.1183/13993003.01228-2017. Print 2017 Dec. No abstract available.

9.
10.

MTA3 Regulates Extravillous Trophoblast Invasion Through NuRD Complex.

Chen Y, Khoo SK, Leach R, Wang K.

AIMS Med Sci. 2017;4(1):17-27. doi: 10.3934/medsci.2017.1.17. Epub 2017 Jan 16.

11.

Environment Changes Genetic Effects on Respiratory Conditions and Allergic Phenotypes.

Song Y, Schwager MJ, Backer V, Guo J, Porsbjerg C, Khoo SK, Laing IA, Moses EK, LeSouëf P, Zhang GB.

Sci Rep. 2017 Jul 24;7(1):6342. doi: 10.1038/s41598-017-06791-y.

12.

Genetic Variants in the IL-4/IL-13 Pathway Influence Measles Vaccine Responses and Vaccine Failure in Children from Mozambique.

Clifford HD, Hayden CM, Khoo SK, Naniche D, Mandomando IM, Zhang G, Richmond P, Le Souëf PN.

Viral Immunol. 2017 Sep;30(7):472-478. doi: 10.1089/vim.2017.0014. Epub 2017 Jun 8.

PMID:
28594599
13.

High fractional exhaled nitric oxide and sputum eosinophils are associated with an increased risk of future virus-induced exacerbations: A prospective cohort study.

Bjerregaard A, Laing IA, Backer V, Sverrild A, Khoo SK, Chidlow G, Sikazwe C, Smith DW, Le Souëf P, Porsbjerg C.

Clin Exp Allergy. 2017 Aug;47(8):1007-1013. doi: 10.1111/cea.12935. Epub 2017 May 9.

PMID:
28390083
14.

Characteristics associated with clinical severity and inflammatory phenotype of naturally occurring virus-induced exacerbations of asthma in adults.

Bjerregaard A, Laing IA, Poulsen N, Backer V, Sverrild A, Fally M, Khoo SK, Barrett L, Baltic S, Thompson PJ, Chidlow G, Sikazwe C, Smith DW, Bochkov YA, Le Souëf P, Porsbjerg C.

Respir Med. 2017 Feb;123:34-41. doi: 10.1016/j.rmed.2016.12.010. Epub 2016 Dec 18.

15.

RNA sequencing of archived neonatal dried blood spots.

Bybjerg-Grauholm J, Hagen CM, Khoo SK, Johannesen ML, Hansen CS, Bækvad-Hansen M, Christiansen M, Hougaard DM, Hollegaard MV.

Mol Genet Metab Rep. 2016 Dec 24;10:33-37. doi: 10.1016/j.ymgmr.2016.12.004. eCollection 2017 Mar.

16.

Chromosome instability drives phenotypic switching to metastasis.

Gao C, Su Y, Koeman J, Haak E, Dykema K, Essenberg C, Hudson E, Petillo D, Khoo SK, Vande Woude GF.

Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14793-14798. doi: 10.1073/pnas.1618215113. Epub 2016 Dec 5.

17.

Effect of storage time on gene expression data acquired from unfrozen archived newborn blood spots.

Ho NT, Busik JV, Resau JH, Paneth N, Khoo SK.

Mol Genet Metab. 2016 Nov;119(3):207-213. doi: 10.1016/j.ymgme.2016.08.001. Epub 2016 Aug 18.

18.

No simple answers for the Finnish and Russian Karelia allergy contrast: Methylation of CD14 gene.

Khoo SK, Mäkelä M, Chandler D, Schultz EN, Jamieson SE, Goldblatt J, Haahtela T, LeSouëf P, Zhang G.

Pediatr Allergy Immunol. 2016 Nov;27(7):721-727. doi: 10.1111/pai.12612. Epub 2016 Sep 12.

PMID:
27434019
19.

Rhinovirus C is associated with wheezing and rhinovirus A is associated with pneumonia in hospitalized children in Morocco.

Annamalay AA, Jroundi I, Bizzintino J, Khoo SK, Zhang G, Lehmann D, Laing IA, Gern J, Goldblatt J, Mahraoui C, Benmessaoud R, Moraleda C, Bassat Q, Le Souëf P.

J Med Virol. 2017 Apr;89(4):582-588. doi: 10.1002/jmv.24684. Epub 2016 Sep 30.

PMID:
27677921
20.

Clinical characteristics of eosinophilic asthma exacerbations.

Bjerregaard A, Laing IA, Backer V, Fally M, Khoo SK, Chidlow G, Sikazwe C, Smith DW, Le Souëf P, Porsbjerg C.

Respirology. 2017 Feb;22(2):295-300. doi: 10.1111/resp.12905. Epub 2016 Sep 21.

PMID:
27649851
21.

Erratum: Discovery of a highly potent glucocorticoid for asthma treatment.

He Y, Shi J, Yi W, Ren X, Gao X, Li J, Wu N, Weaver K, Xie Q, Khoo SK, Yang T, Huang X, Melcher K, Xu HE.

Cell Discov. 2016 Jan 26;2:15051. doi: 10.1038/celldisc.2015.51. eCollection 2016.

22.

Rhinovirus species and clinical features in children hospitalised with pneumonia from Mozambique.

Annamalay AA, Lanaspa M, Khoo SK, Madrid L, Acácio S, Zhang G, Laing IA, Gern J, Goldblatt J, Bizzintino J, Lehmann D, Le Souëf PN, Bassat Q.

Trop Med Int Health. 2016 Sep;21(9):1171-80. doi: 10.1111/tmi.12743. Epub 2016 Jul 26.

23.

Respiratory viruses in young South African children with acute lower respiratory infections and interactions with HIV.

Annamalay AA, Abbott S, Sikazwe C, Khoo SK, Bizzintino J, Zhang G, Laing I, Chidlow GR, Smith DW, Gern J, Goldblatt J, Lehmann D, Green RJ, Le Souëf PN.

J Clin Virol. 2016 Aug;81:58-63. doi: 10.1016/j.jcv.2016.06.002. Epub 2016 Jun 4.

PMID:
27317881
24.

Western environment/lifestyle is associated with increased genome methylation and decreased gene expression in Chinese immigrants living in Australia.

Zhang G, Wang K, Schultz E, Khoo SK, Zhang X, Annamalay A, Laing IA, Hales BJ, Goldblatt J, Le Souëf PN.

Environ Mol Mutagen. 2016 Jan;57(1):65-73. doi: 10.1002/em.21989. Epub 2015 Dec 16.

PMID:
26671525
25.

Altered expression of microRNA-451 in eutopic endometrium of baboons (Papio anubis) with endometriosis.

Joshi NR, Su RW, Chandramouli GV, Khoo SK, Jeong JW, Young SL, Lessey BA, Fazleabas AT.

Hum Reprod. 2015 Dec;30(12):2881-91. doi: 10.1093/humrep/dev229. Epub 2015 Sep 14.

26.

Recurrent rhinovirus detections in children following a rhinovirus-induced wheezing exacerbation: A retrospective study.

Halmø Hürdum S, Zhang G, Khoo SK, Bizzintino J, Franks KM, Lindsay K, Keil AD, Cox DW, Goldblatt J, Bochkov YA, Gern J, Ulrik CS, Souëf PN, Laing IA.

Int J Pediatr Child Health. 2015 Aug;3(1):10-18. doi: 10.12974/2311-8687.2015.03.01.2.

27.

Gene expression profiling of archived dried blood spot samples from the Danish Neonatal Screening Biobank.

Grauholm J, Khoo SK, Nickolov RZ, Poulsen JB, Bækvad-Hansen M, Hansen CS, Hougaard DM, Hollegaard MV.

Mol Genet Metab. 2015 Nov;116(3):119-24. doi: 10.1016/j.ymgme.2015.06.011. Epub 2015 Jul 11.

PMID:
26212339
28.

Rhinovirus-C detection in children presenting with acute respiratory infection to hospital in Brazil.

Fawkner-Corbett DW, Khoo SK, Duarte CM, Bezerra PG, Bochkov YA, Gern JE, Le Souef PN, McNamara PS.

J Med Virol. 2016 Jan;88(1):58-63. doi: 10.1002/jmv.24300.

29.

Disruption of tubular Flcn expression as a mouse model for renal tumor induction.

Chen J, Huang D, Rubera I, Futami K, Wang P, Zickert P, Khoo SK, Dykema K, Zhao P, Petillo D, Cao B, Zhang Z, Si S, Schoen SR, Yang XJ, Zhou M, Xiao GQ, Wu G, Nordenskjöld M, Tauc M, Williams BO, Furge KA, Teh BT.

Kidney Int. 2015 Nov;88(5):1057-69. doi: 10.1038/ki.2015.177. Epub 2015 Jun 17.

PMID:
26083655
30.

Management of interstitial ectopic pregnancy with intravenous methotrexate: An extended study of a standardised regimen.

Tanaka K, Baartz D, Khoo SK.

Aust N Z J Obstet Gynaecol. 2015 Apr;55(2):176-80. doi: 10.1111/ajo.12315. Epub 2015 Apr 14.

PMID:
25870950
31.

Lower anti-echovirus antibody responses in children presenting to hospital with asthma exacerbations.

Iwasaki J, Chai LY, Khoo SK, Bizzintino J, Laing IA, Le Souëf PN, Thomas WR, Hales BJ.

Clin Exp Allergy. 2015 Oct;45(10):1523-30. doi: 10.1111/cea.12501.

PMID:
25640320
32.

Discovery of a highly potent glucocorticoid for asthma treatment.

He Y, Shi J, Yi W, Ren X, Gao X, Li J, Wu N, Weaver K, Xie Q, Khoo SK, Yang T, Huang X, Melcher K, Xu HE.

Cell Discov. 2015;1. pii: 15035. Epub 2015 Dec 15.

33.

Carotid ultrasound pulsatility indices and cardiovascular risk in Australian women.

Oughton JA, Rose S, Galloway G, Khoo SK, O'Neill S, Coulthard A.

J Med Imaging Radiat Oncol. 2015 Feb;59(1):20-5. doi: 10.1111/1754-9485.12250. Epub 2014 Oct 21.

PMID:
25335853
34.

Maternal Genetic Variants of IL4/IL13 Pathway Genes on IgE With "Western or Eastern Environments/Lifestyles".

Zhang G, Khoo SK, Mäkelä MJ, Candelaria P, Hayden CM, von Hertzen L, Laatikainen T, Vartiainen E, Goldblatt J, Haahtela T, LeSouëf PN.

Allergy Asthma Immunol Res. 2014 Jul;6(4):350-6. doi: 10.4168/aair.2014.6.4.350. Epub 2014 Mar 20.

35.

Comparison of rhinovirus antibody titers in children with asthma exacerbations and species-specific rhinovirus infection.

Iwasaki J, Smith WA, Khoo SK, Bizzintino J, Zhang G, Cox DW, Laing IA, Le Souëf PN, Thomas WR, Hales BJ.

J Allergy Clin Immunol. 2014 Jul;134(1):25-32. doi: 10.1016/j.jaci.2014.03.014. Epub 2014 Apr 24.

36.

Plasma advanced oxidative protein products are associated with anti-oxidative stress pathway genes and malaria in a longitudinal cohort.

Zhang G, Skorokhod OA, Khoo SK, Aguilar R, Wiertsema S, Nhabomba AJ, Marrocco T, McNamara-Smith M, Manaca MN, Barbosa A, Quintó L, Hayden CM, Goldblatt J, Guinovart C, Alonso PL, Dobaño C, Schwarzer E, LeSouëf PN.

Malar J. 2014 Apr 3;13:134. doi: 10.1186/1475-2875-13-134.

37.

Mapping the protein interaction network for TFIIB-related factor Brf1 in the RNA polymerase III preinitiation complex.

Khoo SK, Wu CC, Lin YC, Lee JC, Chen HT.

Mol Cell Biol. 2014 Feb;34(3):551-9. doi: 10.1128/MCB.00910-13. Epub 2013 Nov 25.

38.

Comparison of frozen and unfrozen blood spots for gene expression studies.

Wei C, Lu Q, Khoo SK, Lenski M, Fichorova RN, Leviton A, Paneth N.

J Pediatr. 2014 Jan;164(1):189-191.e1. doi: 10.1016/j.jpeds.2013.09.025. Epub 2013 Oct 25.

39.

Overexpression of HGF Promotes HBV-Induced Hepatocellular Carcinoma Progression and Is an Effective Indicator for Met-Targeting Therapy.

Xie Q, Su Y, Dykema K, Johnson J, Koeman J, De Giorgi V, Huang A, Schlegel R, Essenburg C, Kang L, Iwaya K, Seki S, Khoo SK, Zhang B, Buonaguro F, Marincola FM, Furge K, Vande Woude GF, Shinomiya N.

Genes Cancer. 2013 Jul;4(7-8):247-60. doi: 10.1177/1947601913501075.

40.

Impact of CD14 promoter variants on measles vaccine responses and vaccine failure in children from Australia and Mozambique.

Clifford HD, Hayden CM, Khoo SK, Naniche D, Mandomando IM, Zhang G, Richmond P, Le Souëf PN.

Tissue Antigens. 2013 Dec;82(6):420-2. doi: 10.1111/tan.12226. Epub 2013 Oct 21. No abstract available.

PMID:
24147858
41.

Human rhinovirus species C infection in young children with acute wheeze is associated with increased acute respiratory hospital admissions.

Cox DW, Bizzintino J, Ferrari G, Khoo SK, Zhang G, Whelan S, Lee WM, Bochkov YA, Geelhoed GC, Goldblatt J, Gern JE, Laing IA, Le Souëf PN.

Am J Respir Crit Care Med. 2013 Dec 1;188(11):1358-64. doi: 10.1164/rccm.201303-0498OC.

42.

Overexpression of asparagine synthetase and matrix metalloproteinase 19 confers cisplatin sensitivity in nasopharyngeal carcinoma cells.

Liu RY, Dong Z, Liu J, Zhou L, Huang W, Khoo SK, Zhang Z, Petillo D, Teh BT, Qian CN, Zhang JT.

Mol Cancer Ther. 2013 Oct;12(10):2157-66. doi: 10.1158/1535-7163.MCT-12-1190. Epub 2013 Aug 16.

43.

High correlations in gene expression between paired umbilical cord blood and neonatal blood of healthy newborns on Guthrie cards.

Slaughter J, Wei C, Korzeniewski SJ, Lu Q, Beck JS, Khoo SK, Brovont A, Maurer J, Martin D, Lenski M, Paneth N.

J Matern Fetal Neonatal Med. 2013 Dec;26(18):1765-7. doi: 10.3109/14767058.2013.804050. Epub 2013 Jul 24.

44.

Roles of CDX2 and EOMES in human induced trophoblast progenitor cells.

Chen Y, Wang K, Gong YG, Khoo SK, Leach R.

Biochem Biophys Res Commun. 2013 Feb 8;431(2):197-202. doi: 10.1016/j.bbrc.2012.12.135. Epub 2013 Jan 8.

45.

Gene expression in archived newborn blood spots distinguishes infants who will later develop cerebral palsy from matched controls.

Ho NT, Furge K, Fu W, Busik J, Khoo SK, Lu Q, Lenski M, Wirth J, Hurvitz E, Dodge N, Resau J, Paneth N.

Pediatr Res. 2013 Apr;73(4 Pt 1):450-6. doi: 10.1038/pr.2012.200. Epub 2012 Dec 26.

46.

The menopausal transition does not appear to accelerate age-related increases in arterial stiffness.

O'Neill SM, Liu J, O'Rourke MF, Khoo SK.

Climacteric. 2013 Feb;16(1):62-9. doi: 10.3109/13697137.2012.739220. Epub 2012 Nov 15.

PMID:
23152960
47.

Evaluation of sex-specific gene expression in archived dried blood spots (DBS).

Resau JH, Ho NT, Dykema K, Faber MS, Busik JV, Nickolov RZ, Furge KA, Paneth N, Jewell S, Khoo SK.

Int J Mol Sci. 2012;13(8):9599-608. doi: 10.3390/ijms13089599. Epub 2012 Aug 2.

48.

Polymorphisms in key innate immune genes and their effects on measles vaccine responses and vaccine failure in children from Mozambique.

Clifford HD, Hayden CM, Khoo SK, Naniche D, Mandomando IM, Zhang G, Richmond P, Le Souëf PN.

Vaccine. 2012 Sep 21;30(43):6180-5. doi: 10.1016/j.vaccine.2012.07.063. Epub 2012 Aug 4.

PMID:
22871352
49.

Towards validation of use of an Australian reference database for the diagnosis of osteoporosis with DXA.

Wong JC, Travers C, O'Neill S, Khoo SK.

J Med Imaging Radiat Oncol. 2012 Jun;56(3):302-4. doi: 10.1111/j.1754-9485.2012.02370.x. Epub 2012 Apr 10.

PMID:
22697327
50.

Interleukin-10 (IL-10) polymorphisms are associated with IL-10 production and clinical malaria in young children.

Zhang G, Manaca MN, McNamara-Smith M, Mayor A, Nhabomba A, Berthoud TK, Khoo SK, Wiertsema S, Aguilar R, Barbosa A, Quintó L, Candelaria P, Schultz EN, Hayden CM, Goldblatt J, Guinovart C, Alonso PL, Lesouëf PN, Dobaño C.

Infect Immun. 2012 Jul;80(7):2316-22. doi: 10.1128/IAI.00261-12. Epub 2012 May 7.

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