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Functional roles of ST8SIA3-mediated sialylation of striatal dopamine D2 and adenosine A2A receptors.

Lin CY, Lai HL, Chen HM, Siew JJ, Hsiao CT, Chang HC, Liao KS, Tsai SC, Wu CY, Kitajima K, Sato C, Khoo KH, Chern Y.

Transl Psychiatry. 2019 Aug 27;9(1):209. doi: 10.1038/s41398-019-0529-z.


Cross-sectional study of perceptions of qualities of a good medical teacher among medical students from first year to final year.

Low MJW, Khoo KSM, Kuan WS, Ooi SBS.

Singapore Med J. 2019 Aug 16. doi: 10.11622/smedj.2019097. [Epub ahead of print]


Impact of various microalgal-bacterial populations on municipal wastewater bioremediation and its energy feasibility for lipid-based biofuel production.

Leong WH, Azella Zaine SN, Ho YC, Uemura Y, Lam MK, Khoo KS, Kiatkittipong W, Cheng CK, Show PL, Lim JW.

J Environ Manage. 2019 Nov 1;249:109384. doi: 10.1016/j.jenvman.2019.109384. Epub 2019 Aug 13.


Expression of AoNHX1 increases salt tolerance of rice and Arabidopsis, and bHLH transcription factors regulate AtNHX1 and AtNHX6 in Arabidopsis.

Krishnamurthy P, Vishal B, Khoo K, Rajappa S, Loh CS, Kumar PP.

Plant Cell Rep. 2019 Oct;38(10):1299-1315. doi: 10.1007/s00299-019-02450-w. Epub 2019 Jul 26.


Extraction of natural astaxanthin from Haematococcus pluvialis using liquid biphasic flotation system.

Khoo KS, Chew KW, Ooi CW, Ong HC, Ling TC, Show PL.

Bioresour Technol. 2019 Oct;290:121794. doi: 10.1016/j.biortech.2019.121794. Epub 2019 Jul 12.


Prevalence of pre-existing dysglycaemia among inpatients with acute coronary syndrome and associations with outcomes.

Mahendran DC, Hamilton G, Weiss J, Churilov L, Lew J, Khoo K, Lam Q, Robbins R, Hart GK, Johnson D, Hare DL, Farouque O, Zajac JD, Ekinci EI.

Diabetes Res Clin Pract. 2019 Aug;154:130-137. doi: 10.1016/j.diabres.2019.07.002. Epub 2019 Jul 4.


Recent advances in biorefinery of astaxanthin from Haematococcus pluvialis.

Khoo KS, Lee SY, Ooi CW, Fu X, Miao X, Ling TC, Show PL.

Bioresour Technol. 2019 Sep;288:121606. doi: 10.1016/j.biortech.2019.121606. Epub 2019 Jun 4. Review.


Development of a metabolic syndrome severity score and its association with incident diabetes in an Asian population-results from a longitudinal cohort in Singapore.

Low S, Khoo KCJ, Wang J, Irwan B, Sum CF, Subramaniam T, Lim SC, Wong TKM.

Endocrine. 2019 Jul;65(1):73-80. doi: 10.1007/s12020-019-01970-5. Epub 2019 Jun 3.


Color Patterning of Luminescent Perovskites via Light-Mediated Halide Exchange with Haloalkanes.

Wong YC, Wu WB, Wang T, Ng JA, Khoo KH, Wu J, Tan ZK.

Adv Mater. 2019 Jun;31(24):e1901247. doi: 10.1002/adma.201901247. Epub 2019 Apr 22.


Advances toward mapping the full extent of protein site-specific O-GalNAc glycosylation that better reflects underlying glycomic complexity.

Khoo KH.

Curr Opin Struct Biol. 2019 Jun;56:146-154. doi: 10.1016/ Epub 2019 Mar 16. Review.


The relationship between diabetic retinopathy and psychosocial functioning: a systematic review.

Khoo K, Man REK, Rees G, Gupta P, Lamoureux EL, Fenwick EK.

Qual Life Res. 2019 Aug;28(8):2017-2039. doi: 10.1007/s11136-019-02165-1. Epub 2019 Mar 16. Review.


Novel Zebrafish Mono-α2,8-sialyltransferase (ST8Sia VIII): An Evolutionary Perspective of α2,8-Sialylation.

Chang LY, Teppa E, Noel M, Gilormini PA, Decloquement M, Lion C, Biot C, Mir AM, Cogez V, Delannoy P, Khoo KH, Petit D, Guérardel Y, Harduin-Lepers A.

Int J Mol Sci. 2019 Jan 31;20(3). pii: E622. doi: 10.3390/ijms20030622.


Fine mapping of Rha2 in barley reveals candidate genes for resistance against cereal cyst nematode.

Van Gansbeke B, Khoo KHP, Lewis JG, Chalmers KJ, Mather DE.

Theor Appl Genet. 2019 May;132(5):1309-1320. doi: 10.1007/s00122-019-03279-3. Epub 2019 Jan 18.


Non-syndromic craniosynostosis treated by frontal orbital advancement: A case report.

Khoo KW, Arman Zaharil MS, Mohd Ali MZ.

Med J Malaysia. 2018 Dec;73(6):423-424.


Systems glycomics of adult zebrafish identifies organ-specific sialylation and glycosylation patterns.

Yamakawa N, Vanbeselaere J, Chang LY, Yu SY, Ducrocq L, Harduin-Lepers A, Kurata J, Aoki-Kinoshita KF, Sato C, Khoo KH, Kitajima K, Guerardel Y.

Nat Commun. 2018 Nov 7;9(1):4647. doi: 10.1038/s41467-018-06950-3.


Routine use of HbA1c amongst inpatients hospitalised with decompensated heart failure and the association of dysglycaemia with outcomes.

Khoo K, Lew J, Neef P, Kearney L, Churilov L, Robbins R, Tan A, Hachem M, Owen-Jones L, Lam Q, Hart GK, Wilson A, Sumithran P, Johnson D, Srivastava PM, Farouque O, Burrell LM, Zajac JD, Ekinci EI.

Sci Rep. 2018 Sep 10;8(1):13564. doi: 10.1038/s41598-018-31473-8.


A locus on barley chromosome 5H affects adult plant resistance to powdery mildew.

Gupta S, Vassos E, Sznajder B, Fox R, Khoo KHP, Loughman R, Chalmers KJ, Mather DE.

Mol Breed. 2018;38(8):103. doi: 10.1007/s11032-018-0858-2. Epub 2018 Jul 28.


Using routine HbA1c measurements in stroke and the associations of dysglycaemia with stroke outcomes.

Lew J, Thijs V, Churilov L, Donnan G, Park W, Robbins R, Hart GK, Bladin C, Khoo K, Lau LH, Tan A, Lam Q, Johnson D, Zajac JD, Ekinci EI.

J Diabetes Complications. 2018 Nov;32(11):1056-1061. doi: 10.1016/j.jdiacomp.2018.08.013. Epub 2018 Aug 18.


Identifying Specific and Differentially Linked Glycosyl Residues in Mammalian Glycans by Targeted LC-MS Analysis.

Huang YL, Jhou BY, Chen SF, Khoo KH.

Anal Sci. 2018 Sep 10;34(9):1049-1054. doi: 10.2116/analsci.18SCP01. Epub 2018 Aug 24.


Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1.

Cha JH, Yang WH, Xia W, Wei Y, Chan LC, Lim SO, Li CW, Kim T, Chang SS, Lee HH, Hsu JL, Wang HL, Kuo CW, Chang WC, Hadad S, Purdie CA, McCoy AM, Cai S, Tu Y, Litton JK, Mittendorf EA, Moulder SL, Symmans WF, Thompson AM, Piwnica-Worms H, Chen CH, Khoo KH, Hung MC.

Mol Cell. 2018 Aug 16;71(4):606-620.e7. doi: 10.1016/j.molcel.2018.07.030.


Increased levels of RECQ5 shift DNA repair from canonical to alternative pathways.

Olson HC, Davis L, Kiianitsa K, Khoo KJ, Liu Y, Knijnenburg TA, Maizels N.

Nucleic Acids Res. 2018 Oct 12;46(18):9496-9509. doi: 10.1093/nar/gky727.


Distinct substrate specificities of human GlcNAc-6-sulfotransferases revealed by mass spectrometry-based sulfoglycomic analysis.

Yu SY, Hsiao CT, Izawa M, Yusa A, Ishida H, Nakamura S, Yagi H, Kannagi R, Khoo KH.

J Biol Chem. 2018 Sep 28;293(39):15163-15177. doi: 10.1074/jbc.RA118.001937. Epub 2018 Aug 9.


In vitro antidermatophytic activity and cytotoxicity of extracts derived from medicinal plants and marine algae.

Sit NW, Chan YS, Lai SC, Lim LN, Looi GT, Tay PL, Tee YT, Woon YY, Khoo KS, Ong HC.

J Mycol Med. 2018 Sep;28(3):561-567. doi: 10.1016/j.mycmed.2018.07.001. Epub 2018 Jul 27.


The C-terminal p6 domain of the HIV-1 Pr55Gag precursor is required for specific binding to the genomic RNA.

Dubois N, Khoo KK, Ghossein S, Seissler T, Wolff P, McKinstry WJ, Mak J, Paillart JC, Marquet R, Bernacchi S.

RNA Biol. 2018;15(7):923-936. doi: 10.1080/15476286.2018.1481696. Epub 2018 Aug 4.


The role of triglyceride glucose index in development of Type 2 diabetes mellitus.

Low S, Khoo KCJ, Irwan B, Sum CF, Subramaniam T, Lim SC, Wong TKM.

Diabetes Res Clin Pract. 2018 Sep;143:43-49. doi: 10.1016/j.diabres.2018.06.006. Epub 2018 Jun 21.


Antibody-assisted target identification reveals afatinib, an EGFR covalent inhibitor, down-regulating ribonucleotide reductase.

Yu CH, Chou CC, Tu HF, Huang WC, Ho YY, Khoo KH, Lee MS, Chang GD.

Oncotarget. 2018 Apr 20;9(30):21512-21529. doi: 10.18632/oncotarget.25177. eCollection 2018 Apr 20.


STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion.

Hsu JM, Xia W, Hsu YH, Chan LC, Yu WH, Cha JH, Chen CT, Liao HW, Kuo CW, Khoo KH, Hsu JL, Li CW, Lim SO, Chang SS, Chen YC, Ren GX, Hung MC.

Nat Commun. 2018 May 15;9(1):1908. doi: 10.1038/s41467-018-04313-6.


Intrastructural Help: Harnessing T Helper Cells Induced by Licensed Vaccines for Improvement of HIV Env Antibody Responses to Virus-Like Particle Vaccines.

Elsayed H, Nabi G, McKinstry WJ, Khoo KK, Mak J, Salazar AM, Tenbusch M, Temchura V, Überla K.

J Virol. 2018 Jun 29;92(14). pii: e00141-18. doi: 10.1128/JVI.00141-18. Print 2018 Jul 15.


Distinctive and Complementary MS2 Fragmentation Characteristics for Identification of Sulfated Sialylated N-Glycopeptides by nanoLC-MS/MS Workflow.

Kuo CW, Guu SY, Khoo KH.

J Am Soc Mass Spectrom. 2018 Jun;29(6):1166-1178. doi: 10.1007/s13361-018-1919-9. Epub 2018 Apr 11.


Alterations of the Human Skin N- and O-Glycome in Basal Cell Carcinoma and Squamous Cell Carcinoma.

Möginger U, Grunewald S, Hennig R, Kuo CW, Schirmeister F, Voth H, Rapp E, Khoo KH, Seeberger PH, Simon JC, Kolarich D.

Front Oncol. 2018 Mar 21;8:70. doi: 10.3389/fonc.2018.00070. eCollection 2018.


How an intrinsic ligand tunes the activity of a potassium channel.

Khoo KK, Pless SA.

J Gen Physiol. 2018 Apr 2;150(4):517-520. doi: 10.1085/jgp.201812011. Epub 2018 Mar 22. No abstract available.


Target identification reveals protein arginine methyltransferase 1 is a potential target of phenyl vinyl sulfone and its derivatives.

Yu CH, Chou CC, Lee DY, Khoo KH, Chang GD.

Biosci Rep. 2018 Apr 20;38(2). pii: BSR20171717. doi: 10.1042/BSR20171717. Print 2018 Apr 26.


Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1.

Li CW, Lim SO, Chung EM, Kim YS, Park AH, Yao J, Cha JH, Xia W, Chan LC, Kim T, Chang SS, Lee HH, Chou CK, Liu YL, Yeh HC, Perillo EP, Dunn AK, Kuo CW, Khoo KH, Hsu JL, Wu Y, Hsu JM, Yamaguchi H, Huang TH, Sahin AA, Hortobagyi GN, Yoo SS, Hung MC.

Cancer Cell. 2018 Feb 12;33(2):187-201.e10. doi: 10.1016/j.ccell.2018.01.009.


Diet soft drink is associated with increased odds of proliferative diabetic retinopathy.

Fenwick EK, Gan AT, Man RE, Sabanayagam C, Gupta P, Khoo K, Aravindhan A, Wong TY, Lamoureux EL.

Clin Exp Ophthalmol. 2018 Sep;46(7):767-776. doi: 10.1111/ceo.13154. Epub 2018 Feb 23.


Antifungal and cytotoxic activities of selected medicinal plants from Malaysia.

Chan YS, Cheah YH, Chong PZ, Khor HL, Teh WS, Khoo KS, Ong HC, Sit NW.

Pak J Pharm Sci. 2018 Jan;31(1):119-127.


Composition and Bioactivity of Essential Oil from Citrus grandis (L.) Osbeck 'Mato Peiyu' Leaf.

Tsai ML, Lin CD, Khoo KA, Wang MY, Kuan TK, Lin WC, Zhang YN, Wang YY.

Molecules. 2017 Dec 5;22(12). pii: E2154. doi: 10.3390/molecules22122154.


Concerted mass spectrometry-based glycomic approach for precision mapping of sulfo sialylated N-glycans on human peripheral blood mononuclear cells and lymphocytes.

Chen JY, Huang HH, Yu SY, Wu SJ, Kannagi R, Khoo KH.

Glycobiology. 2018 Dec 1;28(1):9-20. doi: 10.1093/glycob/cwx091.


Advancing a High Throughput Glycotope-centric Glycomics Workflow Based on nanoLC-MS2-product Dependent-MS3 Analysis of Permethylated Glycans.

Hsiao CT, Wang PW, Chang HC, Chen YY, Wang SH, Chern Y, Khoo KH.

Mol Cell Proteomics. 2017 Dec;16(12):2268-2280. doi: 10.1074/mcp.TIR117.000156. Epub 2017 Oct 24.


Fibronectin in cell adhesion and migration via N-glycosylation.

Hsiao CT, Cheng HW, Huang CM, Li HR, Ou MH, Huang JR, Khoo KH, Yu HW, Chen YQ, Wang YK, Chiou A, Kuo JC.

Oncotarget. 2017 Aug 7;8(41):70653-70668. doi: 10.18632/oncotarget.19969. eCollection 2017 Sep 19.


Glycomics and Glycoproteomics.

Rudd P, Karlsson NG, Khoo KH, Packer NH.

In: Varki A, Cummings RD, Esko JD, Stanley P, Hart GW, Aebi M, Darvill AG, Kinoshita T, Packer NH, Prestegard JH, Schnaar RL, Seeberger PH, editors. Essentials of Glycobiology [Internet]. 3rd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2015-2017. Chapter 51.


van der Waals Bonded Co/h-BN Contacts to Ultrathin Black Phosphorus Devices.

Avsar A, Tan JY, Luo X, Khoo KH, Yeo Y, Watanabe K, Taniguchi T, Quek SY, Özyilmaz B.

Nano Lett. 2017 Sep 13;17(9):5361-5367. doi: 10.1021/acs.nanolett.7b01817. Epub 2017 Aug 16.


Tunable room-temperature magnetic skyrmions in Ir/Fe/Co/Pt multilayers.

Soumyanarayanan A, Raju M, Gonzalez Oyarce AL, Tan AKC, Im MY, Petrović AP, Ho P, Khoo KH, Tran M, Gan CK, Ernult F, Panagopoulos C.

Nat Mater. 2017 Sep;16(9):898-904. doi: 10.1038/nmat4934. Epub 2017 Jul 17.


Investigation of twenty selected medicinal plants from Malaysia for anti-Chikungunya virus activity.

Chan YS, Khoo KS, Sit NWW.

Int Microbiol. 2016 Sep;19(3):175-182. doi: 10.2436/20.1501.01.275.


Adapting Data-Independent Acquisition for Mass Spectrometry-Based Protein Site-Specific N-Glycosylation Analysis.

Pan KT, Chen CC, Urlaub H, Khoo KH.

Anal Chem. 2017 Apr 18;89(8):4532-4539. doi: 10.1021/acs.analchem.6b04996. Epub 2017 Apr 7.


The thermodynamics of Pr55Gag-RNA interaction regulate the assembly of HIV.

Tanwar HS, Khoo KK, Garvey M, Waddington L, Leis A, Hijnen M, Velkov T, Dumsday GJ, McKinstry WJ, Mak J.

PLoS Pathog. 2017 Feb 21;13(2):e1006221. doi: 10.1371/journal.ppat.1006221. eCollection 2017 Feb.


Plasma Protein Binding Structure-Activity Relationships Related to the N-Terminus of Daptomycin.

Schneider EK, Huang JX, Carbone V, Han M, Zhu Y, Nang S, Khoo KK, Mak J, Cooper MA, Li J, Velkov T.

ACS Infect Dis. 2017 Mar 10;3(3):249-258. doi: 10.1021/acsinfecdis.7b00015. Epub 2017 Feb 10.


Origin of Contact Resistance at Ferromagnetic Metal-Graphene Interfaces.

Khoo KH, Leong WS, Thong JT, Quek SY.

ACS Nano. 2016 Dec 27;10(12):11219-11227. doi: 10.1021/acsnano.6b06286. Epub 2016 Nov 21.


Acyclovir-Polyethylene Glycol 6000 Binary Dispersions: Mechanistic Insights.

Venkateskumar K, Parasuraman S, Gunasunderi R, Sureshkumar K, Nayak MM, Shah SAA, Khoo K, Kai HW.

AAPS PharmSciTech. 2017 Aug;18(6):2085-2094. doi: 10.1208/s12249-016-0686-9. Epub 2016 Dec 21.


The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data.

Liu Y, McBride R, Stoll M, Palma AS, Silva L, Agravat S, Aoki-Kinoshita KF, Campbell MP, Costello CE, Dell A, Haslam SM, Karlsson NG, Khoo KH, Kolarich D, Novotny MV, Packer NH, Ranzinger R, Rapp E, Rudd PM, Struwe WB, Tiemeyer M, Wells L, York WS, Zaia J, Kettner C, Paulson JC, Feizi T, Smith DF.

Glycobiology. 2016 Nov 22. [Epub ahead of print]


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