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Items: 1 to 50 of 96

1.

Targeting cancer with nano-bullets: curcumin, EGCG, resveratrol and quercetin on flying carpets.

Aras A, Khokhar AR, Qureshi MZ, Silva MF, Sobczak-Kupiec A, Pineda EA, Hechenleitner AA, Farooqi AA.

Asian Pac J Cancer Prev. 2014;15(9):3865-71. Review.

2.

Ionizing radiations induce apoptosis in TRAIL resistant cancer cells: in vivo and in vitro analysis.

Silva MF, Khokhar AR, Qureshi MZ, Farooqi AA.

Asian Pac J Cancer Prev. 2014;15(5):1905-7. Review.

3.

Recruitment of trimeric proliferating cell nuclear antigen by G1-phase cyclin-dependent kinases following DNA damage with platinum-based antitumour agents.

He G, Kuang J, Koomen J, Kobayashi R, Khokhar AR, Siddik ZH.

Br J Cancer. 2013 Oct 29;109(9):2378-88. doi: 10.1038/bjc.2013.613. Epub 2013 Oct 8.

4.

The impact of S- and G2-checkpoint response on the fidelity of G1-arrest by cisplatin and its comparison to a non-cross-resistant platinum(IV) analog.

He G, Kuang J, Khokhar AR, Siddik ZH.

Gynecol Oncol. 2011 Aug;122(2):402-9. doi: 10.1016/j.ygyno.2011.04.034. Epub 2011 May 18.

5.

Upregulation of p27 and its inhibition of CDK2/cyclin E activity following DNA damage by a novel platinum agent are dependent on the expression of p21.

He G, Kuang J, Huang Z, Koomen J, Kobayashi R, Khokhar AR, Siddik ZH.

Br J Cancer. 2006 Dec 4;95(11):1514-24. Epub 2006 Nov 7.

6.

Phase II study of a liposome-entrapped cisplatin analog (L-NDDP) administered intrapleurally and pathologic response rates in patients with malignant pleural mesothelioma.

Lu C, Perez-Soler R, Piperdi B, Walsh GL, Swisher SG, Smythe WR, Shin HJ, Ro JY, Feng L, Truong M, Yalamanchili A, Lopez-Berestein G, Hong WK, Khokhar AR, Shin DM.

J Clin Oncol. 2005 May 20;23(15):3495-501.

PMID:
15908659
7.

Induction of p21 by p53 following DNA damage inhibits both Cdk4 and Cdk2 activities.

He G, Siddik ZH, Huang Z, Wang R, Koomen J, Kobayashi R, Khokhar AR, Kuang J.

Oncogene. 2005 Apr 21;24(18):2929-43.

PMID:
15735718
8.
9.

Management of macular pucker.

Khokhar AR, Rab KF, Akhtar HU.

J Coll Physicians Surg Pak. 2003 Dec;13(12):701-3.

PMID:
15569556
10.

Increased sensitivity of a metastatic model of prostate cancer to a novel tetravalent platinum analog.

Mujoo K, Watanabe M, Khokhar AR, Siddik ZH.

Prostate. 2005 Jan 1;62(1):91-100.

PMID:
15389812
11.

Outcome of macular hole surgery.

Khokhar AR, Faiz-ur-Rab K, Akhtar HU.

J Coll Physicians Surg Pak. 2003 Oct;13(10):569-72.

PMID:
14588170
12.

Phase I clinical and pharmacological study of intraperitoneal cis-bis-neodecanoato( trans- R, R-1, 2-diaminocyclohexane)-platinum II entrapped in multilamellar liposome vesicles.

Verschraegen CF, Kumagai S, Davidson R, Feig B, Mansfield P, Lee SJ, Maclean DS, Hu W, Khokhar AR, Siddik ZH.

J Cancer Res Clin Oncol. 2003 Oct;129(10):549-55. Epub 2003 Aug 29.

PMID:
14513369
13.

Status of p53 phosphorylation and function in sensitive and resistant human cancer models exposed to platinum-based DNA damaging agents.

Mujoo K, Watanabe M, Nakamura J, Khokhar AR, Siddik ZH.

J Cancer Res Clin Oncol. 2003 Dec;129(12):709-18. Epub 2003 Sep 26.

PMID:
14513366
14.

cis-1,4-diaminocyclohexane-Pt(II) and -(IV) adducts with DNA bases and nucleosides.

Ali MS, Khokhar AR.

J Inorg Biochem. 2003 Sep 1;96(4):452-6.

PMID:
13678810
15.
16.

Bimodal effects of 1R,2R-diaminocyclohexane(trans-diacetato)(dichloro)platinum(IV) on cell cycle checkpoints.

Kuang J, He G, Huang Z, Khokhar AR, Siddik ZH.

Clin Cancer Res. 2001 Nov;7(11):3629-39.

17.

Synthesis and Characterization of Novel Axial Dichloroplatinum(IV) Cisplatin Analogues: Crystal Structure of an Axial Dichloro Complex [Pt(cis-1,4-DACH)(trans-Cl(2))(CBDCA)].(1)/(2)MeOH.

Shamsuddin S, van Hal JW, Stark JL, Whitmire KH, Khokhar AR.

Inorg Chem. 1997 Dec 3;36(25):5969-5971. No abstract available.

PMID:
11670225
18.

Neutron activation of NDDP, a liposomal platinum antitumor agent.

MacLean DS, Khokhar AR, Perez-Soler R.

Cancer Biother Radiopharm. 2000 Jun;15(3):253-9.

PMID:
10941532
19.
20.
21.
22.

Role of p53 in the ability of 1,2-diaminocyclohexane-diacetato-dichloro-Pt(IV) to circumvent cisplatin resistance.

Siddik ZH, Hagopian GS, Thai G, Tomisaki S, Toyomasu T, Khokhar AR.

J Inorg Biochem. 1999 Oct;77(1-2):65-70. Review.

PMID:
10626356
24.

Evaluation of toxicosis of liposome-encapsulated cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II) in clinically normal cats.

Fox LE, Toshach K, Calderwood-Mays M, Khokhar AR, Kubilis P, Perez-Soler R, MacEwen EG.

Am J Vet Res. 1999 Feb;60(2):257-63.

PMID:
10048562
25.

Synthesis, characterization, and antitumor activity of new platinum(IV) trans-carboxylate complexes: crystal structure of [Pt(cis-1,4-DACH)trans-(acetate)2Cl2].

Shamsuddin S, Santillan CC, Stark JL, Whitmire KH, Siddik ZH, Khokhar AR.

J Inorg Biochem. 1998 Aug;71(1-2):29-35.

PMID:
9755489
27.

Phase I clinical and pharmacological study of liposome-entrapped NDDP administered intrapleurally in patients with malignant pleural effusions.

Perez-Soler R, Shin DM, Siddik ZH, Murphy WK, Huber M, Lee SJ, Khokhar AR, Hong WK.

Clin Cancer Res. 1997 Mar;3(3):373-9.

28.
29.
31.

In vivo antitumor activity of cis-bis-neodecanoato-trans-R,R-1, 2-diaminocyclohexane platinum(II) formulated in long-circulating liposomes.

Mori A, Wu SP, Han I, Khokhar AR, Perez-Soler R, Huang L.

Cancer Chemother Pharmacol. 1996;37(5):435-44.

PMID:
8599866
32.
33.

Tetravalent platinum complexes with ammine/amine carrier ligand configuration: circumvention of platinum resistance in vivo.

Siddik ZH, Thai G, Yoshida M, Zhang YP, Khokhar AR.

Anticancer Drug Des. 1994 Dec;9(6):495-509.

PMID:
7880375
34.
37.
38.

Glutathione-mediated modulation of tetraplatin activity against sensitive and resistant tumor cells.

Kido Y, Khokhar AR, Siddik ZH.

Biochem Pharmacol. 1994 Apr 29;47(9):1635-42.

PMID:
8185678
39.

Modulatory effect of axial and equatorial ligands on antitumor activities of trans-1R,2R-diaminocyclohexane platinum(IV) complexes.

Siddik ZH, al-Baker S, Thai G, Khokhar AR.

Anticancer Drug Des. 1994 Apr;9(2):139-51.

PMID:
8166929
40.

Synthesis and antitumor activity of 1,2-diaminocyclohexane platinum(IV) complexes.

Khokhar AR, al-Baker S, Siddik ZH.

J Inorg Biochem. 1994 Apr;54(1):39-47.

PMID:
8151310
41.

Synthesis, characterization, and antitumor activity of amine platinum(II) and (IV) tellurate complexes.

Khokhar AR, Xu Q, Siddik ZH.

J Inorg Biochem. 1994 Mar;53(4):295-301.

PMID:
8169608
42.

Cell death and DNA fragmentation induced by liposomal platinum(II) complex, L-NDDP in A2780 and A2780/PDD cells.

Han I, Ling YH, Khokhar AR, Perez-Soler R.

Anticancer Res. 1994 Mar-Apr;14(2A):421-6.

PMID:
8017841
43.

Pharmacokinetics of tetraplatin administered intraperitoneally with reduced glutathione in mice.

Kido Y, Khokhar AR, Yoshida M, Thai GW, Siddik ZH.

Drug Metab Dispos. 1994 Mar-Apr;22(2):312-7.

PMID:
8013287
44.
45.
46.

Antitumor activity of isomeric 1,2-diaminocyclohexane platinum(IV) complexes.

Siddik ZH, al-Baker S, Thai G, Khokhar AR.

J Cancer Res Clin Oncol. 1994;120(7):409-14.

PMID:
8188734
47.

Preparation and characterization of liposomes containing a lipophilic cisplatin derivative for clinical use.

Perez-Soler R, Francis K, al-Baker S, Pilkiewicz F, Khokhar AR.

J Microencapsul. 1994 Jan-Feb;11(1):41-54.

PMID:
8138874
48.

Kinetics of tissue disposition of cis-ammine/cyclohexylamine-dichloroplatinum(II) and cisplatin in mice bearing FSaIIC tumors.

Yoshida M, Khokhar AR, Zhang YP, Thai G, Siddik ZH.

Cancer Chemother Pharmacol. 1994;35(1):38-44.

PMID:
7987975
49.

Ammine/amine platinum (II) complexes effective in vivo against murine tumors sensitive or resistant to cisplatin and tetraplatin.

Siddik ZH, Thai G, Yoshida M, Zhang YP, Khokhar AR.

J Cancer Res Clin Oncol. 1994;120(10):571-7.

PMID:
7929527
50.

Cellular pharmacology of liposomal cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum(II) in A2780/S and A2780/PDD cells.

Han I, Ling YH, al-Baker S, Khokhar AR, Perez-Soler R.

Cancer Res. 1993 Oct 15;53(20):4913-9.

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