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Items: 1 to 50 of 56


Cerebellar modulation of the reward circuitry and social behavior.

Carta I, Chen CH, Schott AL, Dorizan S, Khodakhah K.

Science. 2019 Jan 18;363(6424). pii: eaav0581. doi: 10.1126/science.aav0581.


Increased susceptibility to cortical spreading depression and epileptiform activity in a mouse model for FHM2.

Kros L, Lykke-Hartmann K, Khodakhah K.

Sci Rep. 2018 Nov 16;8(1):16959. doi: 10.1038/s41598-018-35285-8.


Aberrant cerebellar Purkinje cell activity as the cause of motor attacks in a mouse model of episodic ataxia type 2.

Tara E, Vitenzon A, Hess E, Khodakhah K.

Dis Model Mech. 2018 Sep 21;11(9). pii: dmm034181. doi: 10.1242/dmm.034181.


Cerebellar involvement in migraine.

Kros L, Angueyra Aristizábal CA, Khodakhah K.

Cephalalgia. 2018 Oct;38(11):1782-1791. doi: 10.1177/0333102417752120. Epub 2018 Jan 22. Review.


It's not just the basal ganglia: Cerebellum as a target for dystonia therapeutics.

Tewari A, Fremont R, Khodakhah K.

Mov Disord. 2017 Nov;32(11):1537-1545. doi: 10.1002/mds.27123. Epub 2017 Aug 26. Review.


Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump.

Isaksen TJ, Kros L, Vedovato N, Holm TH, Vitenzon A, Gadsby DC, Khodakhah K, Lykke-Hartmann K.

PLoS Genet. 2017 May 4;13(5):e1006763. doi: 10.1371/journal.pgen.1006763. eCollection 2017 May.


Aminopyridines for the treatment of neurologic disorders.

Strupp M, Teufel J, Zwergal A, Schniepp R, Khodakhah K, Feil K.

Neurol Clin Pract. 2017 Feb;7(1):65-76. doi: 10.1212/CPJ.0000000000000321. Review.


A role for cerebellum in the hereditary dystonia DYT1.

Fremont R, Tewari A, Angueyra C, Khodakhah K.

Elife. 2017 Feb 15;6. pii: e22775. doi: 10.7554/eLife.22775.


Current Opinions and Areas of Consensus on the Role of the Cerebellum in Dystonia.

Shakkottai VG, Batla A, Bhatia K, Dauer WT, Dresel C, Niethammer M, Eidelberg D, Raike RS, Smith Y, Jinnah HA, Hess EJ, Meunier S, Hallett M, Fremont R, Khodakhah K, LeDoux MS, Popa T, Gallea C, Lehericy S, Bostan AC, Strick PL.

Cerebellum. 2017 Apr;16(2):577-594. doi: 10.1007/s12311-016-0825-6.


Selective expression of mutant huntingtin during development recapitulates characteristic features of Huntington's disease.

Molero AE, Arteaga-Bracho EE, Chen CH, Gulinello M, Winchester ML, Pichamoorthy N, Gokhan S, Khodakhah K, Mehler MF.

Proc Natl Acad Sci U S A. 2016 May 17;113(20):5736-41. doi: 10.1073/pnas.1603871113. Epub 2016 May 2.


The Limited Utility of Multiunit Data in Differentiating Neuronal Population Activity.

Keller CJ, Chen C, Lado FA, Khodakhah K.

PLoS One. 2016 Apr 25;11(4):e0153154. doi: 10.1371/journal.pone.0153154. eCollection 2016.


Developmental change in the contribution of voltage-gated Ca(2+) channels to the pacemaking of deep cerebellar nuclei neurons.

Alviña K, Tara E, Khodakhah K.

Neuroscience. 2016 May 13;322:171-7. doi: 10.1016/j.neuroscience.2016.02.031. Epub 2016 Feb 21.


Recurrent Feedback Loops in Associative Learning.

Person AL, Khodakhah K.

Neuron. 2016 Feb 3;89(3):427-30. doi: 10.1016/j.neuron.2016.01.037.


A dystonia-like movement disorder with brain and spinal neuronal defects is caused by mutation of the mouse laminin β1 subunit, Lamb1.

Liu YB, Tewari A, Salameh J, Arystarkhova E, Hampton TG, Brashear A, Ozelius LJ, Khodakhah K, Sweadner KJ.

Elife. 2015 Dec 24;4. pii: e11102. doi: 10.7554/eLife.11102.


Neuroscience: Decrypting a brain enigma.

Khodakhah K.

Nature. 2015 Oct 15;526(7573):326-7. doi: 10.1038/526326a. No abstract available.


Aberrant Purkinje cell activity is the cause of dystonia in a shRNA-based mouse model of Rapid Onset Dystonia-Parkinsonism.

Fremont R, Tewari A, Khodakhah K.

Neurobiol Dis. 2015 Oct;82:200-212. doi: 10.1016/j.nbd.2015.06.004. Epub 2015 Jun 17.


Rescue of homeostatic regulation of striatal excitability and locomotor activity in a mouse model of Huntington's disease.

Cao Y, Bartolomé-Martín D, Rotem N, Rozas C, Dellal SS, Chacon MA, Kadriu B, Gulinello M, Khodakhah K, Faber DS.

Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):2239-44. doi: 10.1073/pnas.1405748112. Epub 2015 Feb 2.


Short latency cerebellar modulation of the basal ganglia.

Chen CH, Fremont R, Arteaga-Bracho EE, Khodakhah K.

Nat Neurosci. 2014 Dec;17(12):1767-75. doi: 10.1038/nn.3868. Epub 2014 Nov 17.


Abnormal high-frequency burst firing of cerebellar neurons in rapid-onset dystonia-parkinsonism.

Fremont R, Calderon DP, Maleki S, Khodakhah K.

J Neurosci. 2014 Aug 27;34(35):11723-32. doi: 10.1523/JNEUROSCI.1409-14.2014.


The neuronal code(s) of the cerebellum.

Heck DH, De Zeeuw CI, Jaeger D, Khodakhah K, Person AL.

J Neurosci. 2013 Nov 6;33(45):17603-9. doi: 10.1523/JNEUROSCI.2759-13.2013. Review.


Alternative approaches to modeling hereditary dystonias.

Fremont R, Khodakhah K.

Neurotherapeutics. 2012 Apr;9(2):315-22. doi: 10.1007/s13311-012-0113-1. Review.


Efficient generation of reciprocal signals by inhibition.

Park SM, Tara E, Khodakhah K.

J Neurophysiol. 2012 May;107(9):2453-62. doi: 10.1152/jn.00083.2012. Epub 2012 Feb 1.


Neuroscience: Spikes timed through inhibition.

Medina JF, Khodakhah K.

Nature. 2012 Jan 25;481(7382):446-7. doi: 10.1038/481446a. No abstract available.


The role of interneurons in shaping Purkinje cell responses in the cerebellar cortex.

Dizon MJ, Khodakhah K.

J Neurosci. 2011 Jul 20;31(29):10463-73. doi: 10.1523/JNEUROSCI.1350-11.2011.


The neural substrates of rapid-onset Dystonia-Parkinsonism.

Calderon DP, Fremont R, Kraenzlin F, Khodakhah K.

Nat Neurosci. 2011 Mar;14(3):357-65. doi: 10.1038/nn.2753. Epub 2011 Feb 6.


The therapeutic mode of action of 4-aminopyridine in cerebellar ataxia.

Alviña K, Khodakhah K.

J Neurosci. 2010 May 26;30(21):7258-68. doi: 10.1523/JNEUROSCI.3582-09.2010.


KCa channels as therapeutic targets in episodic ataxia type-2.

Alviña K, Khodakhah K.

J Neurosci. 2010 May 26;30(21):7249-57. doi: 10.1523/JNEUROSCI.6341-09.2010.


The functional equivalence of ascending and parallel fiber inputs in cerebellar computation.

Walter JT, Dizon MJ, Khodakhah K.

J Neurosci. 2009 Jul 1;29(26):8462-73. doi: 10.1523/JNEUROSCI.5718-08.2009.


Large conductance calcium-activated potassium channels affect both spontaneous firing and intracellular calcium concentration in cerebellar Purkinje neurons.

Womack MD, Hoang C, Khodakhah K.

Neuroscience. 2009 Sep 15;162(4):989-1000. doi: 10.1016/j.neuroscience.2009.05.016. Epub 2009 May 14.


The advantages of linear information processing for cerebellar computation.

Walter JT, Khodakhah K.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4471-6. doi: 10.1073/pnas.0812348106. Epub 2009 Feb 20.


T-type calcium channels mediate rebound firing in intact deep cerebellar neurons.

Alviña K, Ellis-Davies G, Khodakhah K.

Neuroscience. 2009 Jan 23;158(2):635-41. doi: 10.1016/j.neuroscience.2008.09.052. Epub 2008 Oct 8.


Questioning the role of rebound firing in the cerebellum.

Alviña K, Walter JT, Kohn A, Ellis-Davies G, Khodakhah K.

Nat Neurosci. 2008 Nov;11(11):1256-8. doi: 10.1038/nn.2195. Epub 2008 Sep 28.


Selective regulation of spontaneous activity of neurons of the deep cerebellar nuclei by N-type calcium channels in juvenile rats.

Alviña K, Khodakhah K.

J Physiol. 2008 May 15;586(10):2523-38. doi: 10.1113/jphysiol.2007.148197. Epub 2008 Mar 27.


The linear computational algorithm of cerebellar Purkinje cells.

Walter JT, Khodakhah K.

J Neurosci. 2006 Dec 13;26(50):12861-72.


Biochemical confinements without walls in aspiny neurons.

Castillo PE, Khodakhah K.

Nat Neurosci. 2006 Jun;9(6):719-20. No abstract available.


Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia.

Walter JT, Alviña K, Womack MD, Chevez C, Khodakhah K.

Nat Neurosci. 2006 Mar;9(3):389-97. Epub 2006 Feb 12.


Kv1 channels selectively prevent dendritic hyperexcitability in rat Purkinje cells.

Khavandgar S, Walter JT, Sageser K, Khodakhah K.

J Physiol. 2005 Dec 1;569(Pt 2):545-57. Epub 2005 Oct 6.


Dendritic control of spontaneous bursting in cerebellar Purkinje cells.

Womack MD, Khodakhah K.

J Neurosci. 2004 Apr 7;24(14):3511-21.


Characterization of large conductance Ca2+-activated K+ channels in cerebellar Purkinje neurons.

Womack MD, Khodakhah K.

Eur J Neurosci. 2002 Oct;16(7):1214-22.


Inositol 1,4,5-triphosphate-evoked responses in midbrain dopamine neurons.

Morikawa H, Imani F, Khodakhah K, Williams JT.

J Neurosci. 2000 Oct 15;20(20):RC103.


Impaired calcium release in cerebellar Purkinje neurons maintained in culture.

Womack MD, Walker JW, Khodakhah K.

J Gen Physiol. 2000 Mar;115(3):339-46.


Charge immobilization caused by modification of internal cysteines in squid Na channels.

Khodakhah K, Melishchuk A, Armstrong CM.

Biophys J. 1998 Dec;75(6):2821-9.


Presence and phosphorylation of transcription factors in developing dendrites.

Crino P, Khodakhah K, Becker K, Ginsberg S, Hemby S, Eberwine J.

Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2313-8.


Killing K channels with TEA+.

Khodakhah K, Melishchuk A, Armstrong CM.

Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13335-8.

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