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Items: 8


Rubusoside-assisted solubilization of poorly soluble C6-Ceramide for a pilot pharmacokinetic study.

Chen J, Khiste SK, Fu X, Roy KR, Dong Y, Zhang J, Liu M, Liu YY, Liu Z.

Prostaglandins Other Lipid Mediat. 2020 Feb;146:106402. doi: 10.1016/j.prostaglandins.2019.106402. Epub 2019 Dec 10.


Ceramide-Rubusoside Nanomicelles, a Potential Therapeutic Approach to Target Cancers Carrying p53 Missense Mutations.

Khiste SK, Liu Z, Roy KR, Uddin MB, Hosain SB, Gu X, Nazzal S, Hill RA, Liu YY.

Mol Cancer Ther. 2020 Feb;19(2):564-574. doi: 10.1158/1535-7163.MCT-19-0366. Epub 2019 Oct 23.


An N6-methyladenosine at the transited codon 273 of p53 pre-mRNA promotes the expression of R273H mutant protein and drug resistance of cancer cells.

Uddin MB, Roy KR, Hosain SB, Khiste SK, Hill RA, Jois SD, Zhao Y, Tackett AJ, Liu YY.

Biochem Pharmacol. 2019 Feb;160:134-145. doi: 10.1016/j.bcp.2018.12.014. Epub 2018 Dec 19.


Protein-polysaccharide nanohybrids: Hybridization techniques and drug delivery applications.

Gaber M, Mabrouk MT, Freag MS, Khiste SK, Fang JY, Elkhodairy KA, Elzoghby AO.

Eur J Pharm Biopharm. 2018 Dec;133:42-62. doi: 10.1016/j.ejpb.2018.10.001. Epub 2018 Oct 6. Review.


Inhalable lactoferrin-chondroitin nanocomposites for combined delivery of doxorubicin and ellagic acid to lung carcinoma.

Abd Elwakil MM, Mabrouk MT, Helmy MW, Abdelfattah EA, Khiste SK, Elkhodairy KA, Elzoghby AO.

Nanomedicine (Lond). 2018 Aug;13(16):2015-2035. doi: 10.2217/nnm-2018-0039. Epub 2018 Sep 7.


Incorporation of Fluorescence Ceramide-Based HPLC Assay for Rapidly and Efficiently Assessing Glucosylceramide Synthase In Vivo.

Khiste SK, Hosain SB, Dong Y, Uddin MB, Roy KR, Hill RA, Liu Z, Liu YY.

Sci Rep. 2017 Jun 7;7(1):2976. doi: 10.1038/s41598-017-03320-9.


Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cells.

Hosain SB, Khiste SK, Uddin MB, Vorubindi V, Ingram C, Zhang S, Hill RA, Gu X, Liu YY.

Oncotarget. 2016 Sep 13;7(37):60575-60592. doi: 10.18632/oncotarget.11169.


Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells.

Patwardhan GA, Hosain SB, Liu DX, Khiste SK, Zhao Y, Bielawski J, Jazwinski SM, Liu YY.

Biochim Biophys Acta. 2014 Nov;1841(11):1571-80. doi: 10.1016/j.bbalip.2014.08.017. Epub 2014 Sep 6.

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