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Items: 18


Study of mitochondrial function in placental insufficiency.

Lefebvre T, Roche O, Seegers V, Cherif M, Khiati S, Gueguen N, Desquiret-Dumas V, Geffroy G, Blanchet O, Reynier P, Legendre G, Lenaers G, Procaccio V, Gascoin G.

Placenta. 2018 Jul;67:1-7. doi: 10.1016/j.placenta.2018.05.007. Epub 2018 May 17.


Alteration of Extracellular Nucleotide Metabolism in Pseudoxanthoma Elasticum.

Kauffenstein G, Yegutkin GG, Khiati S, Pomozi V, Le Saux O, Leftheriotis G, Lenaers G, Henrion D, Martin L.

J Invest Dermatol. 2018 Mar 6. pii: S0022-202X(18)30148-9. doi: 10.1016/j.jid.2018.02.023. [Epub ahead of print]


Mitochondrial tyrosyl-DNA phosphodiesterase 2 and its TDP2S short isoform.

Huang SN, Dalla Rosa I, Michaels SA, Tulumello DV, Agama K, Khiati S, Jean SR, Baechler SA, Factor VM, Varma S, Murai J, Miller Jenkins LM, Kelley SO, Pommier Y.

EMBO Rep. 2018 Mar;19(3). pii: e42139. doi: 10.15252/embr.201642139. Epub 2018 Feb 9.


Transcription profiling suggests that mitochondrial topoisomerase IB acts as a topological barrier and regulator of mitochondrial DNA transcription.

Dalla Rosa I, Zhang H, Khiati S, Wu X, Pommier Y.

J Biol Chem. 2017 Dec 8;292(49):20162-20172. doi: 10.1074/jbc.M117.815241. Epub 2017 Oct 11.


Phostine PST3.1a Targets MGAT5 and Inhibits Glioblastoma-Initiating Cell Invasiveness and Proliferation.

Hassani Z, Saleh A, Turpault S, Khiati S, Morelle W, Vignon J, Hugnot JP, Uro-Coste E, Legrand P, Delaforge M, Loiseau S, Clarion L, Lecouvey M, Volle JN, Virieux D, Pirat JL, Duffau H, Bakalara N.

Mol Cancer Res. 2017 Oct;15(10):1376-1387. doi: 10.1158/1541-7786.MCR-17-0120. Epub 2017 Jun 20.


CLUH couples mitochondrial distribution to the energetic and metabolic status.

Wakim J, Goudenege D, Perrot R, Gueguen N, Desquiret-Dumas V, Chao de la Barca JM, Dalla Rosa I, Manero F, Le Mao M, Chupin S, Chevrollier A, Procaccio V, Bonneau D, Logan DC, Reynier P, Lenaers G, Khiati S.

J Cell Sci. 2017 Jun 1;130(11):1940-1951. doi: 10.1242/jcs.201616. Epub 2017 Apr 19.


Biallelic Variants in UBA5 Reveal that Disruption of the UFM1 Cascade Can Result in Early-Onset Encephalopathy.

Colin E, Daniel J, Ziegler A, Wakim J, Scrivo A, Haack TB, Khiati S, Denommé AS, Amati-Bonneau P, Charif M, Procaccio V, Reynier P, Aleck KA, Botto LD, Herper CL, Kaiser CS, Nabbout R, N'Guyen S, Mora-Lorca JA, Assmann B, Christ S, Meitinger T, Strom TM, Prokisch H; FREX Consortium, Miranda-Vizuete A, Hoffmann GF, Lenaers G, Bomont P, Liebau E, Bonneau D.

Am J Hum Genet. 2016 Sep 1;99(3):695-703. doi: 10.1016/j.ajhg.2016.06.030. Epub 2016 Aug 18.


Lack of mitochondrial topoisomerase I (TOP1mt) impairs liver regeneration.

Khiati S, Baechler SA, Factor VM, Zhang H, Huang SY, Dalla Rosa I, Sourbier C, Neckers L, Thorgeirsson SS, Pommier Y.

Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11282-7. doi: 10.1073/pnas.1511016112. Epub 2015 Aug 24.


Poisoning of mitochondrial topoisomerase I by lamellarin D.

Khiati S, Seol Y, Agama K, Dalla Rosa I, Agrawal S, Fesen K, Zhang H, Neuman KC, Pommier Y.

Mol Pharmacol. 2014 Aug;86(2):193-9. doi: 10.1124/mol.114.092833. Epub 2014 Jun 2.


Increased negative supercoiling of mtDNA in TOP1mt knockout mice and presence of topoisomerases IIα and IIβ in vertebrate mitochondria.

Zhang H, Zhang YW, Yasukawa T, Dalla Rosa I, Khiati S, Pommier Y.

Nucleic Acids Res. 2014 Jun;42(11):7259-67. doi: 10.1093/nar/gku384. Epub 2014 May 6.


Mapping topoisomerase sites in mitochondrial DNA with a poisonous mitochondrial topoisomerase I (Top1mt).

Dalla Rosa I, Huang SY, Agama K, Khiati S, Zhang H, Pommier Y.

J Biol Chem. 2014 Jun 27;289(26):18595-602. doi: 10.1074/jbc.M114.555367. Epub 2014 May 5.


Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity.

Khiati S, Dalla Rosa I, Sourbier C, Ma X, Rao VA, Neckers LM, Zhang H, Pommier Y.

Clin Cancer Res. 2014 Sep 15;20(18):4873-81. doi: 10.1158/1078-0432.CCR-13-3373. Epub 2014 Apr 8.


Efficient delivery of therapeutic small nucleic acids to prostate cancer cells using ketal nucleoside lipid nanoparticles.

Luvino D, Khiati S, Oumzil K, Rocchi P, Camplo M, Barthélémy P.

J Control Release. 2013 Dec 28;172(3):954-61. doi: 10.1016/j.jconrel.2013.09.006. Epub 2013 Sep 13.


Unexpected bilayer formation in Langmuir films of nucleolipids.

Desbat B, Arazam N, Khiati S, Tonelli G, Neri W, Barthélémy P, Navailles L.

Langmuir. 2012 May 1;28(17):6816-25. doi: 10.1021/la2047596. Epub 2012 Apr 17.


Nucleoside-lipid-based nanoparticles for cisplatin delivery.

Khiati S, Luvino D, Oumzil K, Chauffert B, Camplo M, Barthélémy P.

ACS Nano. 2011 Nov 22;5(11):8649-55. doi: 10.1021/nn202291k. Epub 2011 Oct 11.


Reduction-triggered delivery using nucleoside-lipid based carriers possessing a cleavable PEG coating.

Oumzil K, Khiati S, Grinstaff MW, Barthélémy P.

J Control Release. 2011 Apr 30;151(2):123-30. doi: 10.1016/j.jconrel.2011.02.008. Epub 2011 Feb 25.


Cationic nucleoside lipids derived from universal bases: A rational approach for siRNA transfection.

Ceballos C, Khiati S, Prata CA, Zhang XX, Giorgio S, Marsal P, Grinstaff MW, Barthélémy P, Camplo M.

Bioconjug Chem. 2010 Jun 16;21(6):1062-9. doi: 10.1021/bc100005k.


Anionic nucleotide--lipids for in vitro DNA transfection.

Khiati S, Pierre N, Andriamanarivo S, Grinstaff MW, Arazam N, Nallet F, Navailles L, Barthélémy P.

Bioconjug Chem. 2009 Sep;20(9):1765-72. doi: 10.1021/bc900163s.


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