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Items: 16


Pituitary cell translation and secretory capacities are enhanced cell autonomously by the transcription factor Creb3l2.

Khetchoumian K, Balsalobre A, Mayran A, Christian H, Chénard V, St-Pierre J, Drouin J.

Nat Commun. 2019 Sep 3;10(1):3960. doi: 10.1038/s41467-019-11894-3.


Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening.

Mayran A, Sochodolsky K, Khetchoumian K, Harris J, Gauthier Y, Bemmo A, Balsalobre A, Drouin J.

Nat Commun. 2019 Aug 23;10(1):3807. doi: 10.1038/s41467-019-11791-9.


Pioneer factor Pax7 deploys a stable enhancer repertoire for specification of cell fate.

Mayran A, Khetchoumian K, Hariri F, Pastinen T, Gauthier Y, Balsalobre A, Drouin J.

Nat Genet. 2018 Feb;50(2):259-269. doi: 10.1038/s41588-017-0035-2. Epub 2018 Jan 22.


Development of a methodology for in vivo follow-up of hepatocellular carcinoma in hepatocyte specific Trim24-null mice treated with myo-inositol trispyrophosphate.

Ignat M, Akladios CY, Lindner V, Khetchoumian K, Teletin M, Muttter D, Aprahamian PM, Marescaux J.

J Exp Clin Cancer Res. 2016 Sep 29;35(1):155.


Mutations in NFKB2 and potential genetic heterogeneity in patients with DAVID syndrome, having variable endocrine and immune deficiencies.

Brue T, Quentien MH, Khetchoumian K, Bensa M, Capo-Chichi JM, Delemer B, Balsalobre A, Nassif C, Papadimitriou DT, Pagnier A, Hasselmann C, Patry L, Schwartzentruber J, Souchon PF, Takayasu S, Enjalbert A, Van Vliet G, Majewski J, Drouin J, Samuels ME.

BMC Med Genet. 2014 Dec 19;15:139. doi: 10.1186/s12881-014-0139-9.


The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling.

Budry L, Balsalobre A, Gauthier Y, Khetchoumian K, L'honoré A, Vallette S, Brue T, Figarella-Branger D, Meij B, Drouin J.

Genes Dev. 2012 Oct 15;26(20):2299-310. doi: 10.1101/gad.200436.112.


TRIM involvement in transcriptional regulation.

Cammas F, Khetchoumian K, Chambon P, Losson R.

Adv Exp Med Biol. 2012;770:59-76. Review.


Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma.

Herquel B, Ouararhni K, Khetchoumian K, Ignat M, Teletin M, Mark M, Béchade G, Van Dorsselaer A, Sanglier-Cianférani S, Hamiche A, Cammas F, Davidson I, Losson R.

Proc Natl Acad Sci U S A. 2011 May 17;108(20):8212-7. doi: 10.1073/pnas.1101544108. Epub 2011 Apr 29.


Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo.

Morsut L, Yan KP, Enzo E, Aragona M, Soligo SM, Wendling O, Mark M, Khetchoumian K, Bressan G, Chambon P, Dupont S, Losson R, Piccolo S.

Development. 2010 Aug 1;137(15):2571-8. doi: 10.1242/dev.053801. Epub 2010 Jun 23.


Trim24 (Tif1 alpha): an essential 'brake' for retinoic acid-induced transcription to prevent liver cancer.

Khetchoumian K, Teletin M, Tisserand J, Herquel B, Ouararhni K, Losson R.

Cell Cycle. 2008 Dec;7(23):3647-52. Epub 2008 Dec 5.


Arterial calcifications and increased expression of vitamin D receptor targets in mice lacking TIF1alpha.

Ignat M, Teletin M, Tisserand J, Khetchoumian K, Dennefeld C, Chambon P, Losson R, Mark M.

Proc Natl Acad Sci U S A. 2008 Feb 19;105(7):2598-603. doi: 10.1073/pnas.0712030105. Epub 2008 Feb 19.


Histopathology in mouse metabolic investigations.

Mark M, Teletin M, Antal C, Wendling O, Auwerx J, Heikkinen S, Khetchoumian K, Argmann CA, Dgheem M.

Curr Protoc Mol Biol. 2007 Apr;Chapter 29:Unit 29B.4. doi: 10.1002/0471142727.mb29b04s78.


Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha.

Khetchoumian K, Teletin M, Tisserand J, Mark M, Herquel B, Ignat M, Zucman-Rossi J, Cammas F, Lerouge T, Thibault C, Metzger D, Chambon P, Losson R.

Nat Genet. 2007 Dec;39(12):1500-6. Epub 2007 Nov 18.


TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids.

Khetchoumian K, Teletin M, Mark M, Lerouge T, Cerviño M, Oulad-Abdelghani M, Chambon P, Losson R.

J Biol Chem. 2004 Nov 12;279(46):48329-41. Epub 2004 Aug 20.

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