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Items: 32


Real-time hyperpolarized 13C magnetic resonance detects increased pyruvate oxidation in pyruvate dehydrogenase kinase 2/4-double knockout mouse livers.

Sharma G, Wu CY, Wynn RM, Gui W, Malloy CR, Sherry AD, Chuang DT, Khemtong C.

Sci Rep. 2019 Nov 11;9(1):16480. doi: 10.1038/s41598-019-52952-6.


Metabolism of hyperpolarized 13 C-acetoacetate to β-hydroxybutyrate detects real-time mitochondrial redox state and dysfunction in heart tissue.

Chen W, Sharma G, Jiang W, Maptue NR, Malloy CR, Sherry AD, Khemtong C.

NMR Biomed. 2019 Jun;32(6):e4091. doi: 10.1002/nbm.4091. Epub 2019 Apr 10.


Effects of deuteration on transamination and oxidation of hyperpolarized 13C-Pyruvate in the isolated heart.

Funk AM, Wen X, Hever T, Maptue NR, Khemtong C, Sherry AD, Malloy CR.

J Magn Reson. 2019 Apr;301:102-108. doi: 10.1016/j.jmr.2019.03.003. Epub 2019 Mar 4.


Brain metabolism modulates neuronal excitability in a mouse model of pyruvate dehydrogenase deficiency.

Jakkamsetti V, Marin-Valencia I, Ma Q, Good LB, Terrill T, Rajasekaran K, Pichumani K, Khemtong C, Hooshyar MA, Sundarrajan C, Patel MS, Bachoo RM, Malloy CR, Pascual JM.

Sci Transl Med. 2019 Feb 20;11(480). pii: eaan0457. doi: 10.1126/scitranslmed.aan0457.


Probing carbohydrate metabolism using hyperpolarized 13 C-labeled molecules.

Singh J, Suh EH, Sharma G, Khemtong C, Sherry AD, Kovacs Z.

NMR Biomed. 2019 Oct;32(10):e4018. doi: 10.1002/nbm.4018. Epub 2018 Nov 26. Review.


Esterase-Catalyzed Production of Hyperpolarized 13C-Enriched Carbon Dioxide in Tissues for Measuring pH.

Maptue N, Jiang W, Harrison C, Funk AM, Sharma G, Malloy CR, Sherry D, Khemtong C.

ACS Sens. 2018 Nov 26;3(11):2232-2236. doi: 10.1021/acssensors.8b01097. Epub 2018 Nov 9.


MOXI Is a Mitochondrial Micropeptide That Enhances Fatty Acid β-Oxidation.

Makarewich CA, Baskin KK, Munir AZ, Bezprozvannaya S, Sharma G, Khemtong C, Shah AM, McAnally JR, Malloy CR, Szweda LI, Bassel-Duby R, Olson EN.

Cell Rep. 2018 Jun 26;23(13):3701-3709. doi: 10.1016/j.celrep.2018.05.058.


A novel inhibitor of pyruvate dehydrogenase kinase stimulates myocardial carbohydrate oxidation in diet-induced obesity.

Wu CY, Satapati S, Gui W, Wynn RM, Sharma G, Lou M, Qi X, Burgess SC, Malloy C, Khemtong C, Sherry AD, Chuang DT, Merritt ME.

J Biol Chem. 2018 Jun 22;293(25):9604-9613. doi: 10.1074/jbc.RA118.002838. Epub 2018 May 8.


Targeting hepatic pyruvate dehydrogenase kinases restores insulin signaling and mitigates ChREBP-mediated lipogenesis in diet-induced obese mice.

Wu CY, Tso SC, Chuang JL, Gui WJ, Lou M, Sharma G, Khemtong C, Qi X, Wynn RM, Chuang DT.

Mol Metab. 2018 Jun;12:12-24. doi: 10.1016/j.molmet.2018.03.014. Epub 2018 Mar 31.


Rational Design of [13 C,D14 ]Tert-butylbenzene as a Scaffold Structure for Designing Long-lived Hyperpolarized 13 C Probes.

Imakura Y, Nonaka H, Takakusagi Y, Ichikawa K, Maptue NR, Funk AM, Khemtong C, Sando S.

Chem Asian J. 2018 Feb 2;13(3):280-283. doi: 10.1002/asia.201701652. Epub 2018 Jan 16.


The rate of lactate production from glucose in hearts is not altered by per-deuteration of glucose.

Funk AM, Anderson BL, Wen X, Hever T, Khemtong C, Kovacs Z, Sherry AD, Malloy CR.

J Magn Reson. 2017 Nov;284:86-93. doi: 10.1016/j.jmr.2017.09.007. Epub 2017 Sep 18.


In vivo assessment of intracellular redox state in rat liver using hyperpolarized [1-13 C]Alanine.

Park JM, Khemtong C, Liu SC, Hurd RE, Spielman DM.

Magn Reson Med. 2017 May;77(5):1741-1748. doi: 10.1002/mrm.26662. Epub 2017 Mar 5.


Influence of Dy3+ and Tb3+ doping on 13C dynamic nuclear polarization.

Niedbalski P, Parish C, Kiswandhi A, Fidelino L, Khemtong C, Hayati Z, Song L, Martins A, Sherry AD, Lumata L.

J Chem Phys. 2017 Jan 7;146(1):014303. doi: 10.1063/1.4973317.


Impact of Ho(3+)-doping on (13)C dynamic nuclear polarization using trityl OX063 free radical.

Kiswandhi A, Niedbalski P, Parish C, Kaur P, Martins A, Fidelino L, Khemtong C, Song L, Sherry AD, Lumata L.

Phys Chem Chem Phys. 2016 Aug 21;18(31):21351-9. doi: 10.1039/c6cp03954e. Epub 2016 Jul 18.


Hyperpolarized 15N-pyridine derivatives as pH-sensitive MRI agents.

Jiang W, Lumata L, Chen W, Zhang S, Kovacs Z, Sherry AD, Khemtong C.

Sci Rep. 2015 Mar 16;5:9104. doi: 10.1038/srep09104.


Hyperpolarized 13C NMR detects rapid drug-induced changes in cardiac metabolism.

Khemtong C, Carpenter NR, Lumata LL, Merritt ME, Moreno KX, Kovacs Z, Malloy CR, Sherry AD.

Magn Reson Med. 2015 Aug;74(2):312-9. doi: 10.1002/mrm.25419. Epub 2014 Aug 28.


The efficiency of DPPH as a polarising agent for DNP-NMR spectroscopy.

Lumata L, Merritt M, Khemtong C, Ratnakar SJ, van Tol J, Yu L, Song L, Kovacs Z.

RSC Adv. 2012 Jan 1;2(33):12812-12817. Epub 2012 Oct 25.


Investigation of In Vivo Targeting Kinetics of α(v)β(3)-Specific Superparamagnetic Nanoprobes by Time-Resolved MRI.

Kessinger CW, Togao O, Khemtong C, Huang G, Takahashi M, Gao J.

Theranostics. 2011 Apr 24;1:263-73.


Off-resonance saturation MRI of superparamagnetic nanoprobes: theoretical models and experimental validations.

Khemtong C, Togao O, Ren J, Kessinger CW, Takahashi M, Sherry AD, Gao J.

J Magn Reson. 2011 Mar;209(1):53-60. doi: 10.1016/j.jmr.2010.12.013. Epub 2011 Jan 5.


In vivo angiogenesis imaging of solid tumors by alpha(v)beta(3)-targeted, dual-modality micellar nanoprobes.

Kessinger CW, Khemtong C, Togao O, Takahashi M, Sumer BD, Gao J.

Exp Biol Med (Maywood). 2010 Aug;235(8):957-65. doi: 10.1258/ebm.2010.010096.


Polymeric micelle nanoparticles for photodynamic treatment of head and neck cancer cells.

Cohen EM, Ding H, Kessinger CW, Khemtong C, Gao J, Sumer BD.

Otolaryngol Head Neck Surg. 2010 Jul;143(1):109-15. doi: 10.1016/j.otohns.2010.03.032.


Beta-lapachone micellar nanotherapeutics for non-small cell lung cancer therapy.

Blanco E, Bey EA, Khemtong C, Yang SG, Setti-Guthi J, Chen H, Kessinger CW, Carnevale KA, Bornmann WG, Boothman DA, Gao J.

Cancer Res. 2010 May 15;70(10):3896-904. doi: 10.1158/0008-5472.CAN-09-3995. Epub 2010 May 11.


Nanonization strategies for poorly water-soluble drugs.

Chen H, Khemtong C, Yang X, Chang X, Gao J.

Drug Discov Today. 2011 Apr;16(7-8):354-60. doi: 10.1016/j.drudis.2010.02.009. Epub 2010 Mar 3. Review.


Off-resonance saturation magnetic resonance imaging of superparamagnetic polymeric micelles.

Khemtong C, Kessinger CW, Togao O, Ren J, Takahashi M, Sherry AD, Gao J.

Conf Proc IEEE Eng Med Biol Soc. 2009;2009:4095-7. doi: 10.1109/IEMBS.2009.5334550.


MRI-visible micellar nanomedicine for targeted drug delivery to lung cancer cells.

Guthi JS, Yang SG, Huang G, Li S, Khemtong C, Kessinger CW, Peyton M, Minna JD, Brown KC, Gao J.

Mol Pharm. 2010 Feb 1;7(1):32-40. doi: 10.1021/mp9001393.


Polymeric nanomedicine for cancer MR imaging and drug delivery.

Khemtong C, Kessinger CW, Gao J.

Chem Commun (Camb). 2009 Jun 28;(24):3497-510. doi: 10.1039/b821865j. Epub 2009 Mar 10. Review.


In vivo off-resonance saturation magnetic resonance imaging of alphavbeta3-targeted superparamagnetic nanoparticles.

Khemtong C, Kessinger CW, Ren J, Bey EA, Yang SG, Guthi JS, Boothman DA, Sherry AD, Gao J.

Cancer Res. 2009 Feb 15;69(4):1651-8. doi: 10.1158/0008-5472.CAN-08-3231. Epub 2009 Feb 3.


A Novel Strategy for Surface Modification of Superparamagnetic Iron Oxide Nanoparticles for Lung Cancer Imaging.

Huang G, Zhang C, Li S, Khemtong C, Yang SG, Tian R, Minna JD, Brown KC, Gao J.

J Mater Chem. 2009;19:6367-6372.


Zinc ferrite nanoparticles as MRI contrast agents.

Bárcena C, Sra AK, Chaubey GS, Khemtong C, Liu JP, Gao J.

Chem Commun (Camb). 2008 May 21;(19):2224-6. doi: 10.1039/b801041b. Epub 2008 Mar 11.


Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems.

Nasongkla N, Bey E, Ren J, Ai H, Khemtong C, Guthi JS, Chin SF, Sherry AD, Boothman DA, Gao J.

Nano Lett. 2006 Nov;6(11):2427-30.


Photochemical patterning of a self-assembled monolayer of 7-diazomethylcarbonyl-2,4,9-trithiaadmantane on gold films via Wolff rearrangement.

Hu J, Liu Y, Khemtong C, El Khoury JM, McAfoos TJ, Taschner IS.

Langmuir. 2004 Jun 8;20(12):4933-8.


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