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Items: 6


The synaptic balance between sumoylation and desumoylation is maintained by the activation of metabotropic mGlu5 receptors.

Schorova L, Pronot M, Poupon G, Prieto M, Folci A, Khayachi A, Brau F, Cassé F, Gwizdek C, Martin S.

Cell Mol Life Sci. 2019 Aug;76(15):3019-3031. doi: 10.1007/s00018-019-03075-8. Epub 2019 Mar 23.


Involvement of Phosphodiesterase 2A Activity in the Pathophysiology of Fragile X Syndrome.

Maurin T, Melancia F, Jarjat M, Castro L, Costa L, Delhaye S, Khayachi A, Castagnola S, Mota E, Di Giorgio A, Servadio M, Drozd M, Poupon G, Schiavi S, Sardone L, Azoulay S, Ciranna L, Martin S, Vincent P, Trezza V, Bardoni B.

Cereb Cortex. 2018 Aug 23. doi: 10.1093/cercor/bhy192. [Epub ahead of print]


Sumoylation regulates FMRP-mediated dendritic spine elimination and maturation.

Khayachi A, Gwizdek C, Poupon G, Alcor D, Chafai M, Cassé F, Maurin T, Prieto M, Folci A, De Graeve F, Castagnola S, Gautier R, Schorova L, Loriol C, Pronot M, Besse F, Brau F, Deval E, Bardoni B, Martin S.

Nat Commun. 2018 Feb 22;9(1):757. doi: 10.1038/s41467-018-03222-y.


In vitro and in vivo regulation of synaptogenesis by the novel antidepressant spadin.

Devader C, Khayachi A, Veyssière J, Moha Ou Maati H, Roulot M, Moreno S, Borsotto M, Martin S, Heurteaux C, Mazella J.

Br J Pharmacol. 2015 May;172(10):2604-17. doi: 10.1111/bph.13083. Epub 2015 Mar 24.


mGlu5 receptors regulate synaptic sumoylation via a transient PKC-dependent diffusional trapping of Ubc9 into spines.

Loriol C, Cassé F, Khayachi A, Poupon G, Chafai M, Deval E, Gwizdek C, Martin S.

Nat Commun. 2014 Oct 14;5:5113. doi: 10.1038/ncomms6113.


Activity-dependent regulation of the sumoylation machinery in rat hippocampal neurons.

Loriol C, Khayachi A, Poupon G, Gwizdek C, Martin S.

Biol Cell. 2013 Jan;105(1):30-45. doi: 10.1111/boc.201200016. Epub 2012 Nov 26.


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