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Items: 1 to 50 of 525

1.

Responses of intestinal virome to silver nanoparticles: safety assessment by classical virology, whole-genome sequencing and bioinformatics approaches.

Gokulan K, Bekele AZ, Drake KL, Khare S.

Int J Nanomedicine. 2018 May 16;13:2857-2867. doi: 10.2147/IJN.S161379. eCollection 2018.

2.

Synthetic analogues of the parasitic worm product ES-62 reduce disease development in in vivo models of lung fibrosis.

Suckling CJ, Mukherjee S, Khalaf AI, Narayan A, Scott FJ, Khare S, Dhakshinamoorthy S, Harnett MM, Harnett W.

Acta Trop. 2018 May 23;185:212-218. doi: 10.1016/j.actatropica.2018.05.015. [Epub ahead of print]

PMID:
29802846
3.

Rosa damascena restrains Plasmodium falciparum progression in vitro and impedes malaria pathogenesis in murine model.

Khare S, Gupta M, Cheema HS, Maurya AK, Rout P, Darokar MP, Pal A.

Biomed Pharmacother. 2018 Jan;97:1654-1662. doi: 10.1016/j.biopha.2017.11.130. Epub 2017 Dec 8.

PMID:
29793328
4.

Multi-Pronged Interactions Underlie Inhibition of α-Synuclein Aggregation by β-Synuclein.

Williams JK, Yang X, Atieh TB, Olson MP, Khare SD, Baum J.

J Mol Biol. 2018 May 18. pii: S0022-2836(18)30448-0. doi: 10.1016/j.jmb.2018.05.024. [Epub ahead of print]

PMID:
29782835
5.

Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity.

Ochocki JD, Khare S, Hess M, Ackerman D, Qiu B, Daisak JI, Worth AJ, Lin N, Lee P, Xie H, Li B, Wubbenhorst B, Maguire TG, Nathanson KL, Alwine JC, Blair IA, Nissim I, Keith B, Simon MC.

Cell Metab. 2018 Jun 5;27(6):1263-1280.e6. doi: 10.1016/j.cmet.2018.04.009. Epub 2018 May 10.

PMID:
29754953
6.

Rapid Mapping of Protein Binding Sites and Conformational Epitopes by Coupling Yeast Surface Display to Chemical Labeling and Deep Sequencing.

Najar TA, Khare S, Varadarajan R.

Methods Mol Biol. 2018;1785:77-88. doi: 10.1007/978-1-4939-7841-0_6.

PMID:
29714013
7.

Opposing actions of developmental trichloroethylene and high-fat-diet co-exposure on markers of lipogenesis and inflammation in autoimmune-prone mice.

Blossom SJ, Fernandes L, Bai S, Khare S, Gokulan K, Yuan Y, Dewall M, Simmen FA, Gilbert KM.

Toxicol Sci. 2018 Apr 12. doi: 10.1093/toxsci/kfy091. [Epub ahead of print]

PMID:
29669109
8.

PR Toxin - Biosynthesis, Genetic Regulation, Toxicological Potential, Prevention and Control Measures: Overview and Challenges.

Dubey MK, Aamir M, Kaushik MS, Khare S, Meena M, Singh S, Upadhyay RS.

Front Pharmacol. 2018 Mar 29;9:288. doi: 10.3389/fphar.2018.00288. eCollection 2018. Review.

9.

Harnessing the bio-mineralization ability of urease producing Serratia marcescens and Enterobacter cloacae EMB19 for remediation of heavy metal cadmium (II).

Bhattacharya A, Naik SN, Khare SK.

J Environ Manage. 2018 Jun 1;215:143-152. doi: 10.1016/j.jenvman.2018.03.055. Epub 2018 Mar 20.

PMID:
29567554
10.

Structure and Inhibitor Specificity of L,D-Transpeptidase (LdtMt2) from Mycobacterium tuberculosis and Antibiotic Resistance: Calcium Binding Promotes Dimer Formation.

Gokulan K, Khare S, Cerniglia CE, Foley SL, Varughese KI.

AAPS J. 2018 Mar 9;20(2):44. doi: 10.1208/s12248-018-0193-x.

PMID:
29524047
11.

Bioprospecting microbes for single-cell oil production from starchy wastes.

Chaturvedi S, Kumari A, Nain L, Khare SK.

Prep Biochem Biotechnol. 2018 Mar 16;48(3):296-302. doi: 10.1080/10826068.2018.1431783. Epub 2018 Mar 5.

PMID:
29424627
12.

Computational assessment of thioether isosteres.

Barrows RD, Blacklock KM, Rablen PR, Khare SD, Knapp S.

J Mol Graph Model. 2018 Mar;80:282-292. doi: 10.1016/j.jmgm.2018.01.018. Epub 2018 Feb 1.

PMID:
29414047
13.

Cholesterol-oxidase-magnetic nanobioconjugates for the production of 4-cholesten-3-one and 4-cholesten-3, 7-dione.

Ghosh S, Ahmad R, Gautam VK, Khare SK.

Bioresour Technol. 2018 Apr;254:91-96. doi: 10.1016/j.biortech.2018.01.030. Epub 2018 Jan 9.

PMID:
29413944
14.

Immobilization of Aspergillus niger cellulase on multiwall carbon nanotubes for cellulose hydrolysis.

Ahmad R, Khare SK.

Bioresour Technol. 2018 Mar;252:72-75. doi: 10.1016/j.biortech.2017.12.082. Epub 2017 Dec 27.

PMID:
29306133
15.

An in vitro study to assess the impact of tetracycline on the human intestinal microbiome.

Jung JY, Ahn Y, Khare S, Gokulan K, Piñeiro SA, Cerniglia CE.

Anaerobe. 2018 Feb;49:85-94. doi: 10.1016/j.anaerobe.2017.12.011. Epub 2017 Dec 30.

PMID:
29294359
16.

One-pot bioprocess for lactic acid production from lignocellulosic agro-wastes by using ionic liquid stable Lactobacillus brevis.

Grewal J, Khare SK.

Bioresour Technol. 2018 Mar;251:268-273. doi: 10.1016/j.biortech.2017.12.056. Epub 2017 Dec 20.

PMID:
29288954
17.

Primary Antiphospholipid Antibody Syndrome Presenting as Unilateral Adrenal Hemorrhage.

Khare S, Patel H, Sutaria G, Sharma R.

Indian J Endocrinol Metab. 2017 Nov-Dec;21(6):932-933. doi: 10.4103/ijem.IJEM_474_17. No abstract available.

18.

A new method for removal of eyelid margin molluscum.

Khare S, Dubey S, Nagar R.

J Am Acad Dermatol. 2018 Jun;78(6):e151-e152. doi: 10.1016/j.jaad.2017.12.036. Epub 2017 Dec 20. No abstract available.

PMID:
29274346
19.

Computational Design of a Photocontrolled Cytosine Deaminase.

Blacklock KM, Yachnin BJ, Woolley GA, Khare SD.

J Am Chem Soc. 2018 Jan 10;140(1):14-17. doi: 10.1021/jacs.7b08709. Epub 2017 Dec 28.

PMID:
29251923
20.

A computational method for the design of nested proteins by loop-directed domain insertion.

Blacklock KM, Yang L, Mulligan VK, Khare SD.

Proteins. 2018 Mar;86(3):354-369. doi: 10.1002/prot.25445. Epub 2018 Jan 24.

PMID:
29250820
21.

New Delhi metallo-β-lactamase - type carbapenemases producing Escherichia coli isolates from hospitalized patients: A pilot study.

Grover SS, Doda A, Gupta N, Gandhoke I, Batra J, Hans C, Khare S.

Indian J Med Res. 2017 Jul;146(1):105-110. doi: 10.4103/ijmr.IJMR_594_15.

22.

Enzyme stabilization via computationally guided protein stapling.

Moore EJ, Zorine D, Hansen WA, Khare SD, Fasan R.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):12472-12477. doi: 10.1073/pnas.1708907114. Epub 2017 Nov 6.

23.

Epidemiological Profile of Acute Viral Encephalitis.

Kumar R, Kumar P, Singh MK, Agarwal D, Jamir B, Khare S, Narayan S.

Indian J Pediatr. 2018 May;85(5):358-363. doi: 10.1007/s12098-017-2481-3. Epub 2017 Oct 27.

PMID:
29076102
24.

Potential of ionic liquids for inhibiting the growth and β-lactamase production by Bacillus cereus EMB20.

Sadaf A, Kumari A, Khare SK.

Int J Biol Macromol. 2018 Feb;107(Pt B):1915-1921. doi: 10.1016/j.ijbiomac.2017.10.053. Epub 2017 Oct 13.

PMID:
29030198
25.

Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition.

Davis KM, Schramma KR, Hansen WA, Bacik JP, Khare SD, Seyedsayamdost MR, Ando N.

Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):10420-10425. doi: 10.1073/pnas.1703663114. Epub 2017 Sep 11.

26.

Effects of residual levels of tetracycline on the barrier functions of human intestinal epithelial cells.

Gokulan K, Cerniglia CE, Thomas C, Pineiro SA, Khare S.

Food Chem Toxicol. 2017 Nov;109(Pt 1):253-263. doi: 10.1016/j.fct.2017.09.004. Epub 2017 Sep 4.

PMID:
28882639
27.

Strengthening laboratory surveillance of antimicrobial resistance in South East Asia.

Shah AS, Karunaratne K, Shakya G, Barreto I, Khare S, Paveenkittiporn W, Wangchuk S, Tin HH, Muhsin MA, Aung L, Bhatia R, Srivastava R, Maryandi DA.

BMJ. 2017 Sep 5;358:j3474. doi: 10.1136/bmj.j3474. No abstract available.

28.

Seroprevalence of transplacentally acquired measles antibodies in HIV-exposed versus HIV-unexposed infants at six months of age.

Jain S, Seth A, Khare S, Chandra J.

Indian J Med Res. 2017 Apr;145(4):536-542. doi: 10.4103/ijmr.IJMR_44_16.

29.

Computation-Guided Design of a Stimulus-Responsive Multienzyme Supramolecular Assembly.

Yang L, Dolan EM, Tan SK, Lin T, Sontag ED, Khare SD.

Chembiochem. 2017 Oct 18;18(20):2000-2006. doi: 10.1002/cbic.201700425. Epub 2017 Sep 1.

PMID:
28799209
30.

Systems Biology Analysis of Temporal In vivo Brucella melitensis and Bovine Transcriptomes Predicts host:Pathogen Protein-Protein Interactions.

Rossetti CA, Drake KL, Lawhon SD, Nunes JS, Gull T, Khare S, Adams LG.

Front Microbiol. 2017 Jul 27;8:1275. doi: 10.3389/fmicb.2017.01275. eCollection 2017.

31.

Design and Evolution of a Macrocyclic Peptide Inhibitor of the Sonic Hedgehog/Patched Interaction.

Owens AE, de Paola I, Hansen WA, Liu YW, Khare SD, Fasan R.

J Am Chem Soc. 2017 Sep 13;139(36):12559-12568. doi: 10.1021/jacs.7b06087. Epub 2017 Aug 30.

PMID:
28759213
32.

A pH-dependent switch promotes β-synuclein fibril formation via glutamate residues.

Moriarty GM, Olson MP, Atieh TB, Janowska MK, Khare SD, Baum J.

J Biol Chem. 2017 Sep 29;292(39):16368-16379. doi: 10.1074/jbc.M117.780528. Epub 2017 Jul 14.

33.

Structure and Functional Characterisation of a Distinctive β-Lactamase from an Environmental Strain EMB20 of Bacillus cereus.

Sadaf A, Sinha R, Khare SK.

Appl Biochem Biotechnol. 2018 Jan;184(1):197-211. doi: 10.1007/s12010-017-2539-8. Epub 2017 Jun 29.

PMID:
28664525
34.

MFPred: Rapid and accurate prediction of protein-peptide recognition multispecificity using self-consistent mean field theory.

Rubenstein AB, Pethe MA, Khare SD.

PLoS Comput Biol. 2017 Jun 26;13(6):e1005614. doi: 10.1371/journal.pcbi.1005614. eCollection 2017 Jun.

35.

The PYRIN domain-only protein POP2 inhibits inflammasome priming and activation.

Ratsimandresy RA, Chu LH, Khare S, de Almeida L, Gangopadhyay A, Indramohan M, Misharin AV, Greaves DR, Perlman H, Dorfleutner A, Stehlik C.

Nat Commun. 2017 Jun 5;8:15556. doi: 10.1038/ncomms15556.

36.

Biodegradation of 7-Ketocholesterol by Rhodococcus erythropolis MTCC 3951: Process optimization and enzymatic insights.

Ghosh S, Khare SK.

Chem Phys Lipids. 2017 Oct;207(Pt B):253-259. doi: 10.1016/j.chemphyslip.2017.05.008. Epub 2017 May 29.

PMID:
28571786
37.

Benchmarking a computational design method for the incorporation of metal ion-binding sites at symmetric protein interfaces.

Hansen WA, Khare SD.

Protein Sci. 2017 Aug;26(8):1584-1594. doi: 10.1002/pro.3194. Epub 2017 May 31.

PMID:
28513090
38.

DNA chip based sensor for amperometric detection of infectious pathogens.

Singh S, Kaushal A, Khare S, Kumar A.

Int J Biol Macromol. 2017 Oct;103:355-359. doi: 10.1016/j.ijbiomac.2017.05.041. Epub 2017 May 11.

PMID:
28502856
39.

Graphene and carbon nanotubes activate different cell surface receptors on macrophages before and after deactivation of endotoxins.

Lahiani MH, Gokulan K, Williams K, Khodakovskaya MV, Khare S.

J Appl Toxicol. 2017 Nov;37(11):1305-1316. doi: 10.1002/jat.3477. Epub 2017 May 9.

PMID:
28485474
40.

Three phase partitioning and spectroscopic characterization of bioactive constituent from halophilic Bacillus subtilis EMB M15.

Yadav N, Gupta MN, Khare SK.

Bioresour Technol. 2017 Oct;242:283-286. doi: 10.1016/j.biortech.2017.04.090. Epub 2017 Apr 26.

PMID:
28478895
41.

A KCNC3 mutation causes a neurodevelopmental, non-progressive SCA13 subtype associated with dominant negative effects and aberrant EGFR trafficking.

Khare S, Nick JA, Zhang Y, Galeano K, Butler B, Khoshbouei H, Rayaprolu S, Hathorn T, Ranum LPW, Smithson L, Golde TE, Paucar M, Morse R, Raff M, Simon J, Nordenskjöld M, Wirdefeldt K, Rincon-Limas DE, Lewis J, Kaczmarek LK, Fernandez-Funez P, Nick HS, Waters MF.

PLoS One. 2017 May 3;12(5):e0173565. doi: 10.1371/journal.pone.0173565. eCollection 2017.

42.

Development of cellulase-nanoconjugates with enhanced ionic liquid and thermal stability for in situ lignocellulose saccharification.

Grewal J, Ahmad R, Khare SK.

Bioresour Technol. 2017 Oct;242:236-243. doi: 10.1016/j.biortech.2017.04.007. Epub 2017 Apr 4.

PMID:
28411048
43.

Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase.

Stanford SM, Aleshin AE, Zhang V, Ardecky RJ, Hedrick MP, Zou J, Ganji SR, Bliss MR, Yamamoto F, Bobkov AA, Kiselar J, Liu Y, Cadwell GW, Khare S, Yu J, Barquilla A, Chung TDY, Mustelin T, Schenk S, Bankston LA, Liddington RC, Pinkerton AB, Bottini N.

Nat Chem Biol. 2017 Jun;13(6):624-632. doi: 10.1038/nchembio.2344. Epub 2017 Mar 27.

44.

Atypical role of sprouty in colorectal cancer: sprouty repression inhibits epithelial-mesenchymal transition.

Zhang Q, Wei T, Shim K, Wright K, Xu K, Palka-Hamblin HL, Jurkevich A, Khare S.

Oncogene. 2017 Jul 13;36(28):4088. doi: 10.1038/onc.2017.56. Epub 2017 Mar 13.

45.

Validity of Current Treatment Protocols to Overcome Hypochondriasis.

Khare S, Srivastava MN.

J Clin Diagn Res. 2017 Jan;11(1):VE01-VE04. doi: 10.7860/JCDR/2017/22509.9262. Epub 2017 Jan 1. Review.

46.

Long-term cardiac (valvulopathy) safety of cabergoline in prolactinoma.

Khare S, Lila AR, Patil R, Phadke M, Kerkar P, Bandgar T, Shah NS.

Indian J Endocrinol Metab. 2017 Jan-Feb;21(1):154-159. doi: 10.4103/2230-8210.196010.

47.

Acute Presentation of Juvenile Dermatomyositis with Subclinical Cardiac Involvement: A Rare Case.

Khera R, Khare S, Singh SK.

J Clin Diagn Res. 2016 Dec;10(12):SD01-SD03. doi: 10.7860/JCDR/2016/20925.9008. Epub 2016 Dec 1.

48.

Engineering carboxypeptidase G2 circular permutations for the design of an autoinhibited enzyme.

Yachnin BJ, Khare SD.

Protein Eng Des Sel. 2017 Apr 1;30(4):321-331. doi: 10.1093/protein/gzx005.

PMID:
28160000
49.

Association of acute toxic encephalopathy with litchi consumption in an outbreak in Muzaffarpur, India, 2014: a case-control study.

Shrivastava A, Kumar A, Thomas JD, Laserson KF, Bhushan G, Carter MD, Chhabra M, Mittal V, Khare S, Sejvar JJ, Dwivedi M, Isenberg SL, Johnson R, Pirkle JL, Sharer JD, Hall PL, Yadav R, Velayudhan A, Papanna M, Singh P, Somashekar D, Pradhan A, Goel K, Pandey R, Kumar M, Kumar S, Chakrabarti A, Sivaperumal P, Kumar AR, Schier JG, Chang A, Graham LA, Mathews TP, Johnson D, Valentin L, Caldwell KL, Jarrett JM, Harden LA, Takeoka GR, Tong S, Queen K, Paden C, Whitney A, Haberling DL, Singh R, Singh RS, Earhart KC, Dhariwal AC, Chauhan LS, Venkatesh S, Srikantiah P.

Lancet Glob Health. 2017 Apr;5(4):e458-e466. doi: 10.1016/S2214-109X(17)30035-9. Epub 2017 Jan 31.

50.

Proteomics approaches for early detection and targeted therapy of hepatocellular carcinoma.

Khare T, Khare S, Ibdah JA.

World J Gastrointest Oncol. 2017 Jan 15;9(1):1-3. doi: 10.4251/wjgo.v9.i1.1.

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