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Items: 1 to 50 of 208

1.

Common variable immunodeficiency-associated endotoxemia promotes early commitment to the T follicular lineage.

Le Coz C, Bengsch B, Khanna C, Trofa M, Ohtani T, Nolan BE, Henrickson SE, Lambert MP, Kim TO, Despotovic JM, Feldman S, Fadugba OO, Takach P, Ruffner M, Jyonouchi S, Heimall J, Sullivan KE, Wherry EJ, Romberg N.

J Allergy Clin Immunol. 2019 Aug 21. pii: S0091-6749(19)31092-9. doi: 10.1016/j.jaci.2019.08.007. [Epub ahead of print]

PMID:
31445098
2.

Glaucoma Drainage Devices and Reasons for Keratoplasty.

Knier CG, Wang F, Baratz K, Khanna CL.

J Glaucoma. 2019 Aug 6. doi: 10.1097/IJG.0000000000001340. [Epub ahead of print]

PMID:
31393312
3.

Provocative questions in osteosarcoma basic and translational biology: A report from the Children's Oncology Group.

Roberts RD, Lizardo MM, Reed DR, Hingorani P, Glover J, Allen-Rhoades W, Fan T, Khanna C, Sweet-Cordero EA, Cash T, Bishop MW, Hegde M, Sertil AR, Koelsche C, Mirabello L, Malkin D, Sorensen PH, Meltzer PS, Janeway KA, Gorlick R, Crompton BD.

Cancer. 2019 Jul 29. doi: 10.1002/cncr.32351. [Epub ahead of print] Review.

PMID:
31355930
4.

Towards the Delivery of Precision Veterinary Cancer Medicine.

Katogiritis A, Khanna C.

Vet Clin North Am Small Anim Pract. 2019 Sep;49(5):809-818. doi: 10.1016/j.cvsm.2019.04.011. Epub 2019 Jun 28. Review.

PMID:
31256903
5.

Polymerase chain reaction for antigen receptor rearrangement: Benchmarking performance of a lymphoid clonality assay in diverse canine sample types.

Ehrhart EJ, Wong S, Richter K, Zismann V, Grimes C, Hendricks W, Khanna C.

J Vet Intern Med. 2019 May;33(3):1392-1402. doi: 10.1111/jvim.15485. Epub 2019 Apr 2.

6.

Myocilin Mutations in Patients With Normal-Tension Glaucoma.

Alward WLM, van der Heide C, Khanna CL, Roos BR, Sivaprasad S, Kam J, Ritch R, Lotery A, Igo RP Jr, Cooke Bailey JN, Stone EM, Scheetz TE, Kwon YH, Pasquale LR, Wiggs JL, Fingert JH; NEIGHBORHOOD Consortium.

JAMA Ophthalmol. 2019 May 1;137(5):559-563. doi: 10.1001/jamaophthalmol.2019.0005.

PMID:
30816940
7.

The Risk of Primary Open-Angle Glaucoma Following Vitreoretinal Surgery-A Population-based Study.

Mansukhani SA, Barkmeier AJ, Bakri SJ, Iezzi R, Pulido JS, Khanna CL, Bennett JR, Hodge DO, Sit AJ.

Am J Ophthalmol. 2019 May;201:85-86. doi: 10.1016/j.ajo.2018.12.012. Epub 2019 Jan 22. No abstract available.

PMID:
30683306
8.

Healthcare Utilization by Glaucoma Patients in a Team Care Model.

Damento GM, Winkler NS, Hodge DO, Khanna SS, Khanna CL.

Semin Ophthalmol. 2018;33(7-8):829-837. doi: 10.1080/08820538.2018.1514059. Epub 2018 Sep 21.

PMID:
30240281
9.

Telemedicine in long-term care of glaucoma patients.

Odden JL, Khanna CL, Choo CM, Zhao B, Shah SM, Stalboerger GM, Bennett JR, Schornack MM.

J Telemed Telecare. 2018 Sep 12:1357633X18797175. doi: 10.1177/1357633X18797175. [Epub ahead of print]

PMID:
30208751
10.

Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis.

Hendricks WPD, Zismann V, Sivaprakasam K, Legendre C, Poorman K, Tembe W, Perdigones N, Kiefer J, Liang W, DeLuca V, Stark M, Ruhe A, Froman R, Duesbery NS, Washington M, Aldrich J, Neff MW, Huentelman MJ, Hayward N, Brown K, Thamm D, Post G, Khanna C, Davis B, Breen M, Sekulic A, Trent JM.

PLoS Genet. 2018 Sep 6;14(9):e1007589. doi: 10.1371/journal.pgen.1007589. eCollection 2018 Sep.

11.

NCI Comparative Oncology Program Testing of Non-Camptothecin Indenoisoquinoline Topoisomerase I Inhibitors in Naturally Occurring Canine Lymphoma.

Burton JH, Mazcko C, LeBlanc A, Covey JM, Ji J, Kinders RJ, Parchment RE, Khanna C, Paoloni M, Lana S, Weishaar K, London C, Kisseberth W, Krick E, Vail D, Childress M, Bryan JN, Barber L, Ehrhart EJ, Kent M, Fan T, Kow K, Northup N, Wilson-Robles H, Tomaszewski J, Holleran JL, Muzzio M, Eiseman J, Beumer JH, Doroshow JH, Pommier Y.

Clin Cancer Res. 2018 Dec 1;24(23):5830-5840. doi: 10.1158/1078-0432.CCR-18-1498. Epub 2018 Jul 30.

PMID:
30061364
12.

Tolerability of oral sorafenib in pet dogs with a diagnosis of cancer.

Foskett A, Manley C, Naramore R, Gordon IK, Stewart BM, Khanna C.

Vet Med (Auckl). 2017 Dec 8;8:97-102. doi: 10.2147/VMRR.S149678. eCollection 2017.

13.

The Risk of Primary Open-Angle Glaucoma Following Vitreoretinal Surgery-A Population-based Study.

Mansukhani SA, Barkmeier AJ, Bakri SJ, Iezzi R, Pulido JS, Khanna CL, Bennett JR, Hodge DO, Sit AJ.

Am J Ophthalmol. 2018 Sep;193:143-155. doi: 10.1016/j.ajo.2018.06.010. Epub 2018 Jun 27.

14.

Provider Agreement in the Assessment of Glaucoma Progression Within a Team Model.

Shah SM, Choo C, Odden J, Zhao B, Fang C, Schornack M, Stalboerger G, Bennett JR, Khanna CL.

J Glaucoma. 2018 Aug;27(8):691-698. doi: 10.1097/IJG.0000000000000994.

PMID:
29870430
15.

Aquaporin-4 and Myelin Oligodendrocyte Glycoprotein Autoantibody Status Predict Outcome of Recurrent Optic Neuritis.

Jitprapaikulsan J, Chen JJ, Flanagan EP, Tobin WO, Fryer JP, Weinshenker BG, McKeon A, Lennon VA, Leavitt JA, Tillema JM, Lucchinetti C, Keegan BM, Kantarci O, Khanna C, Jenkins SM, Spears GM, Sagan J, Pittock SJ.

Ophthalmology. 2018 Oct;125(10):1628-1637. doi: 10.1016/j.ophtha.2018.03.041. Epub 2018 Apr 30.

PMID:
29716788
16.

Corrigendum: Positively selected enhancer elements endow osteosarcoma cells with metastatic competence.

Morrow JJ, Bayles I, Funnell APW, Miller TE, Saiakhova A, Lizardo MM, Bartels CF, Kapteijn MY, Hung S, Mendoza A, Dhillon G, Chee DR, Myers JT, Allen F, Gambarotti M, Righi A, DiFeo A, Rubin BP, Huang AY, Meltzer PS, Helman LJ, Picci P, Versteeg HH, Stamatoyannopoulos JA, Khanna C, Scacheri PC.

Nat Med. 2018 Apr 10;24(4):525. doi: 10.1038/nm0418-525c.

PMID:
29634688
17.

Leveraging Comparative Oncology in the Hopes of Improving Therapies for Breast Cancer.

Khanna C.

Semin Oncol. 2017 Aug;44(4):301. doi: 10.1053/j.seminoncol.2017.11.003. Epub 2017 Nov 23. No abstract available.

PMID:
29526259
18.

Factors Associated With Health-Related Quality of Life in Medically and Surgically Treated Patients With Glaucoma.

Khanna CL, Leske DA, Holmes JM.

JAMA Ophthalmol. 2018 Apr 1;136(4):348-355. doi: 10.1001/jamaophthalmol.2018.0012.

19.

Positively selected enhancer elements endow osteosarcoma cells with metastatic competence.

Morrow JJ, Bayles I, Funnell APW, Miller TE, Saiakhova A, Lizardo MM, Bartels CF, Kapteijn MY, Hung S, Mendoza A, Dhillon G, Chee DR, Myers JT, Allen F, Gambarotti M, Righi A, DiFeo A, Rubin BP, Huang AY, Meltzer PS, Helman LJ, Picci P, Versteeg HH, Stamatoyannopoulos JA, Khanna C, Scacheri PC.

Nat Med. 2018 Feb;24(2):176-185. doi: 10.1038/nm.4475. Epub 2018 Jan 15. Erratum in: Nat Med. 2018 Apr 10;24(4):525.

20.

Activation of the unfolded protein response in sarcoma cells treated with rapamycin or temsirolimus.

Briggs JW, Ren L, Chakrabarti KR, Tsai YC, Weissman AM, Hansen RJ, Gustafson DL, Khan YA, Dinman JD, Khanna C.

PLoS One. 2017 Sep 19;12(9):e0185089. doi: 10.1371/journal.pone.0185089. eCollection 2017.

21.

Osteosarcoma enters a post genomic era with in silico opportunities: Generation of the High Dimensional Database for facilitating sarcoma biology research: A report from the Children's Oncology Group and the QuadW Foundation.

Glover J, Man TK, Barkauskas DA, Hall D, Tello T, Sullivan MB, Gorlick R, Janeway K, Grier H, Lau C, Toretsky JA, Borinstein SC, Khanna C, Fan TM; COG Osteosarcoma Biology Group.

PLoS One. 2017 Jul 21;12(7):e0181204. doi: 10.1371/journal.pone.0181204. eCollection 2017.

22.

Strabismus and binocular diplopia due to advanced glaucomatous visual field loss.

Khanna CL, Holmes JM.

J AAPOS. 2017 Aug;21(4):263-267. doi: 10.1016/j.jaapos.2017.06.009. Epub 2017 Jun 20.

PMID:
28642003
23.

Analysis of a Physician-led, Team-based Care Model for the Treatment of Glaucoma.

Winkler NS, Damento GM, Khanna SS, Hodge DO, Khanna CL.

J Glaucoma. 2017 Aug;26(8):702-707. doi: 10.1097/IJG.0000000000000689.

PMID:
28617721
24.

Obesity and Associated Comorbidities in People and Companion Animals: A One Health Perspective.

Chandler M, Cunningham S, Lund EM, Khanna C, Naramore R, Patel A, Day MJ.

J Comp Pathol. 2017 May;156(4):296-309. doi: 10.1016/j.jcpa.2017.03.006. Epub 2017 Apr 28. Review.

25.

Metabolomics uncovers a link between inositol metabolism and osteosarcoma metastasis.

Ren L, Hong ES, Mendoza A, Issaq S, Tran Hoang C, Lizardo M, LeBlanc A, Khanna C.

Oncotarget. 2017 Jun 13;8(24):38541-38553. doi: 10.18632/oncotarget.15872.

26.

Fuzzy-Contextual Contrast Enhancement.

Parihar A, Verma O, Khanna C.

IEEE Trans Image Process. 2017 Apr;26(4):1810-1819. doi: 10.1109/TIP.2017.2665975. Epub 2017 Feb 8.

PMID:
28186893
27.

Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression.

Lizardo MM, Morrow JJ, Miller TE, Hong ES, Ren L, Mendoza A, Halsey CH, Scacheri PC, Helman LJ, Khanna C.

Neoplasia. 2016 Oct 28;18(11):699-710. doi: 10.1016/j.neo.2016.09.001. [Epub ahead of print]

28.

Diplopia in Medically and Surgically Treated Patients with Glaucoma.

Sun PY, Leske DA, Holmes JM, Khanna CL.

Ophthalmology. 2017 Feb;124(2):257-262. doi: 10.1016/j.ophtha.2016.10.006. Epub 2016 Nov 18.

29.

mTOR Inhibition Mitigates Enhanced mRNA Translation Associated with the Metastatic Phenotype of Osteosarcoma Cells In Vivo.

Morrow JJ, Mendoza A, Koyen A, Lizardo MM, Ren L, Waybright TJ, Hansen RJ, Gustafson DL, Zhou M, Fan TM, Scacheri PC, Khanna C.

Clin Cancer Res. 2016 Dec 15;22(24):6129-6141. Epub 2016 Jun 24.

30.

The current state and a perspective towards the future of osteosarcoma in dogs.

Khanna C.

Vet Comp Oncol. 2016 Jun;14(2):e1-3. doi: 10.1111/vco.12237. No abstract available.

PMID:
27140205
31.

Current state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop.

Hingorani P, Janeway K, Crompton BD, Kadoch C, Mackall CL, Khan J, Shern JF, Schiffman J, Mirabello L, Savage SA, Ladanyi M, Meltzer P, Bult CJ, Adamson PC, Lupo PJ, Mody R, DuBois SG, Parsons DW, Khanna C, Lau C, Hawkins DS, Randall RL, Smith M, Sorensen PH, Plon SE, Skapek SX, Lessnick S, Gorlick R, Reed DR.

Cancer Genet. 2016 May;209(5):182-94. doi: 10.1016/j.cancergen.2016.03.004. Epub 2016 Apr 5. Review.

32.

A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells.

Shin MH, He Y, Marrogi E, Piperdi S, Ren L, Khanna C, Gorlick R, Liu C, Huang J.

PLoS Genet. 2016 Feb 29;12(2):e1005884. doi: 10.1371/journal.pgen.1005884. eCollection 2016 Feb.

33.

A Comparative Oncology Study of Iniparib Defines Its Pharmacokinetic Profile and Biological Activity in a Naturally-Occurring Canine Cancer Model.

Saba C, Paoloni M, Mazcko C, Kisseberth W, Burton JH, Smith A, Wilson-Robles H, Allstadt S, Vail D, Henry C, Lana S, Ehrhart EJ, Charles B, Kent M, Lawrence J, Burgess K, Borgatti A, Suter S, Woods P, Gordon I, Vrignaud P, Khanna C, LeBlanc AK.

PLoS One. 2016 Feb 11;11(2):e0149194. doi: 10.1371/journal.pone.0149194. eCollection 2016.

34.

Perspectives from man's best friend: National Academy of Medicine's Workshop on Comparative Oncology.

LeBlanc AK, Breen M, Choyke P, Dewhirst M, Fan TM, Gustafson DL, Helman LJ, Kastan MB, Knapp DW, Levin WJ, London C, Mason N, Mazcko C, Olson PN, Page R, Teicher BA, Thamm DH, Trent JM, Vail DM, Khanna C.

Sci Transl Med. 2016 Feb 3;8(324):324ps5. doi: 10.1126/scitranslmed.aaf0746. Review. No abstract available.

PMID:
26843188
35.

Defining the Value of a Comparative Approach to Cancer Drug Development.

LeBlanc AK, Mazcko CN, Khanna C.

Clin Cancer Res. 2016 May 1;22(9):2133-8. doi: 10.1158/1078-0432.CCR-15-2347. Epub 2015 Dec 28. Review.

36.

Pharmacokinetics of orally administered low-dose rapamycin in healthy dogs.

Larson JC, Allstadt SD, Fan TM, Khanna C, Lunghofer PJ, Hansen RJ, Gustafson DL, Legendre AM, Galyon GD, LeBlanc AK, Martin-Jimenez T.

Am J Vet Res. 2016 Jan;77(1):65-71. doi: 10.2460/ajvr.77.1.65.

37.

Precision medicine: an opportunity for a paradigm shift in veterinary medicine.

Lloyd KC, Khanna C, Hendricks W, Trent J, Kotlikoff M.

J Am Vet Med Assoc. 2016 Jan 1;248(1):45-8. doi: 10.2460/javma.248.1.45. No abstract available.

38.

Letter to the Editor.

Khanna C, Vail D, Rosenberg M.

J Vet Intern Med. 2016 Jan-Feb;30(1):9. doi: 10.1111/jvim.13790. Epub 2015 Nov 30. No abstract available.

39.

CCL9 Induced by TGFβ Signaling in Myeloid Cells Enhances Tumor Cell Survival in the Premetastatic Organ.

Yan HH, Jiang J, Pang Y, Achyut BR, Lizardo M, Liang X, Hunter K, Khanna C, Hollander C, Yang L.

Cancer Res. 2015 Dec 15;75(24):5283-98. doi: 10.1158/0008-5472.CAN-15-2282-T. Epub 2015 Oct 19.

40.

Comparative Gene Expression Analyses Identify Luminal and Basal Subtypes of Canine Invasive Urothelial Carcinoma That Mimic Patterns in Human Invasive Bladder Cancer.

Dhawan D, Paoloni M, Shukradas S, Choudhury DR, Craig BA, Ramos-Vara JA, Hahn N, Bonney PL, Khanna C, Knapp DW.

PLoS One. 2015 Sep 9;10(9):e0136688. doi: 10.1371/journal.pone.0136688. eCollection 2015.

41.

Osteosarcoma Genetics and Epigenetics: Emerging Biology and Candidate Therapies.

Morrow JJ, Khanna C.

Crit Rev Oncog. 2015;20(3-4):173-97. Review.

42.

Characterization of the metastatic phenotype of a panel of established osteosarcoma cells.

Ren L, Mendoza A, Zhu J, Briggs JW, Halsey C, Hong ES, Burkett SS, Morrow J, Lizardo MM, Osborne T, Li SQ, Luu HH, Meltzer P, Khanna C.

Oncotarget. 2015 Oct 6;6(30):29469-81. doi: 10.18632/oncotarget.5177.

43.

Comparative Aspects of Osteosarcoma Pathogenesis in Humans and Dogs.

Fan TM, Khanna C.

Vet Sci. 2015 Aug 17;2(3):210-230. doi: 10.3390/vetsci2030210. Review.

44.

A Review of Paclitaxel and Novel Formulations Including Those Suitable for Use in Dogs.

Khanna C, Rosenberg M, Vail DM.

J Vet Intern Med. 2015 Jul-Aug;29(4):1006-12. doi: 10.1111/jvim.12596. Review.

45.

Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma.

Paoloni M, Mazcko C, Selting K, Lana S, Barber L, Phillips J, Skorupski K, Vail D, Wilson H, Biller B, Avery A, Kiupel M, LeBlanc A, Bernhardt A, Brunkhorst B, Tighe R, Khanna C.

PLoS One. 2015 Jun 19;10(6):e0129954. doi: 10.1371/journal.pone.0129954. eCollection 2015.

46.

A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma.

Mirabello L, Koster R, Moriarity BS, Spector LG, Meltzer PS, Gary J, Machiela MJ, Pankratz N, Panagiotou OA, Largaespada D, Wang Z, Gastier-Foster JM, Gorlick R, Khanna C, de Toledo SR, Petrilli AS, Patiño-Garcia A, Sierrasesúmaga L, Lecanda F, Andrulis IL, Wunder JS, Gokgoz N, Serra M, Hattinger C, Picci P, Scotlandi K, Flanagan AM, Tirabosco R, Amary MF, Halai D, Ballinger ML, Thomas DM, Davis S, Barkauskas DA, Marina N, Helman L, Otto GM, Becklin KL, Wolf NK, Weg MT, Tucker M, Wacholder S, Fraumeni JF Jr, Caporaso NE, Boland JF, Hicks BD, Vogt A, Burdett L, Yeager M, Hoover RN, Chanock SJ, Savage SA.

Cancer Discov. 2015 Sep;5(9):920-31. doi: 10.1158/2159-8290.CD-15-0125. Epub 2015 Jun 17.

47.

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis.

Moriarity BS, Otto GM, Rahrmann EP, Rathe SK, Wolf NK, Weg MT, Manlove LA, LaRue RS, Temiz NA, Molyneux SD, Choi K, Holly KJ, Sarver AL, Scott MC, Forster CL, Modiano JF, Khanna C, Hewitt SM, Khokha R, Yang Y, Gorlick R, Dyer MA, Largaespada DA.

Nat Genet. 2015 Jun;47(6):615-24. doi: 10.1038/ng.3293. Epub 2015 May 11.

48.

Germline TP53 variants and susceptibility to osteosarcoma.

Mirabello L, Yeager M, Mai PL, Gastier-Foster JM, Gorlick R, Khanna C, Patiño-Garcia A, Sierrasesúmaga L, Lecanda F, Andrulis IL, Wunder JS, Gokgoz N, Barkauskas DA, Zhang X, Vogt A, Jones K, Boland JF, Chanock SJ, Savage SA.

J Natl Cancer Inst. 2015 Apr 20;107(7). pii: djv101. doi: 10.1093/jnci/djv101. Print 2015 Jul.

49.

Type III Collagen Directs Stromal Organization and Limits Metastasis in a Murine Model of Breast Cancer.

Brisson BK, Mauldin EA, Lei W, Vogel LK, Power AM, Lo A, Dopkin D, Khanna C, Wells RG, Puré E, Volk SW.

Am J Pathol. 2015 May;185(5):1471-86. doi: 10.1016/j.ajpath.2015.01.029. Epub 2015 Mar 17.

50.

Trabeculectomy-related complications in Olmsted County, Minnesota, 1985 through 2010.

Olayanju JA, Hassan MB, Hodge DO, Khanna CL.

JAMA Ophthalmol. 2015 May;133(5):574-80. doi: 10.1001/jamaophthalmol.2015.57.

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