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Items: 47


Impact of Cumulative Chemotherapy Dose on Survival With Adjuvant FEC-D Chemotherapy for Breast Cancer.

Veitch Z, Khan OF, Tilley D, Tang PA, Ribnikar D, Stewart DA, Kostaras X, King K, Lupichuk S.

J Natl Compr Canc Netw. 2019 Aug 1;17(8):957-967. doi: 10.6004/jnccn.2019.7286.


Polyimide Electrode-Based Electrical Stimulation Impedes Early Stage Muscle Graft Regeneration.

Srinivasan S, Vyas K, McAvoy M, Calvaresi P, Khan OF, Langer R, Anderson DG, Herr H.

Front Neurol. 2019 Mar 22;10:252. doi: 10.3389/fneur.2019.00252. eCollection 2019.


Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β-induced Serpine1.

McCann JV, Xiao L, Kim DJ, Khan OF, Kowalski PS, Anderson DG, Pecot CV, Azam SH, Parker JS, Tsai YS, Wolberg AS, Turner SD, Tatsumi K, Mackman N, Dudley AC.

J Clin Invest. 2019 Mar 11;130:1654-1670. doi: 10.1172/JCI123106. eCollection 2019 Mar 11.


Immediate-term cognitive impairment following intravenous (IV) chemotherapy: a prospective pre-post design study.

Khan OF, Cusano E, Raissouni S, Pabia M, Haeseker J, Bosma N, Ko JJ, Li H, Kumar A, Vickers MM, Tang PA.

BMC Cancer. 2019 Feb 14;19(1):150. doi: 10.1186/s12885-019-5349-2.


BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension.

Yu Q, Tai YY, Tang Y, Zhao J, Negi V, Culley MK, Pilli J, Sun W, Brugger K, Mayr J, Saggar R, Saggar R, Wallace WD, Ross DJ, Waxman AB, Wendell SG, Mullett SJ, Sembrat J, Rojas M, Khan OF, Dahlman JE, Sugahara M, Kagiyama N, Satoh T, Zhang M, Feng N, Gorcsan J 3rd, Vargas SO, Haley KJ, Kumar R, Graham BB, Langer R, Anderson DG, Wang B, Shiva S, Bertero T, Chan SY.

Circulation. 2019 May 7;139(19):2238-2255. doi: 10.1161/CIRCULATIONAHA.118.035889.


Real-World Outcomes of Adjuvant Chemotherapy for Node-Negative and Node-Positive HER2-Positive Breast Cancer.

Veitch Z, Khan OF, Tilley D, Ribnikar D, Kostaras X, King K, Tang P, Lupichuk S.

J Natl Compr Canc Netw. 2019 Jan;17(1):47-56. doi: 10.6004/jnccn.2018.7066.


Endothelial siRNA delivery in nonhuman primates using ionizable low-molecular weight polymeric nanoparticles.

Khan OF, Kowalski PS, Doloff JC, Tsosie JK, Bakthavatchalu V, Winn CB, Haupt J, Jamiel M, Langer R, Anderson DG.

Sci Adv. 2018 Jun 27;4(6):eaar8409. doi: 10.1126/sciadv.aar8409. eCollection 2018 Jun.


MicroRNA regulation of the MRN complex impacts DNA damage, cellular senescence, and angiogenic signaling.

Espinosa-Diez C, Wilson R, Chatterjee N, Hudson C, Ruhl R, Hipfinger C, Helms E, Khan OF, Anderson DG, Anand S.

Cell Death Dis. 2018 May 24;9(6):632. doi: 10.1038/s41419-018-0690-y.


Multiplexed nanomedicine for brain tumors: nanosized Hercules to tame our Lernaean Hydra inside?

Panek WK, Khan OF, Yu D, Lesniak MS.

Nanomedicine (Lond). 2017 Oct 3. doi: 10.2217/nnm-2017-0260. [Epub ahead of print] No abstract available.


Drug development for breast, colorectal, and non-small cell lung cancers from 1979 to 2014.

Nixon NA, Khan OF, Imam H, Tang PA, Monzon J, Li H, Sun G, Ezeife D, Parimi S, Dowden S, Tam VC.

Cancer. 2017 Dec 1;123(23):4672-4679. doi: 10.1002/cncr.30919. Epub 2017 Aug 17.


Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression.

Yu D, Khan OF, Suvà ML, Dong B, Panek WK, Xiao T, Wu M, Han Y, Ahmed AU, Balyasnikova IV, Zhang HF, Sun C, Langer R, Anderson DG, Lesniak MS.

Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6147-E6156. doi: 10.1073/pnas.1701911114. Epub 2017 Jul 10.


Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy.

Jung K, Heishi T, Khan OF, Kowalski PS, Incio J, Rahbari NN, Chung E, Clark JW, Willett CG, Luster AD, Yun SH, Langer R, Anderson DG, Padera TP, Jain RK, Fukumura D.

J Clin Invest. 2017 Aug 1;127(8):3039-3051. doi: 10.1172/JCI93182. Epub 2017 Jul 10.


An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model.

Chahal JS, Fang T, Woodham AW, Khan OF, Ling J, Anderson DG, Ploegh HL.

Sci Rep. 2017 Mar 21;7(1):252. doi: 10.1038/s41598-017-00193-w.


Polymeric mechanical amplifiers of immune cytokine-mediated apoptosis.

Mitchell MJ, Webster J, Chung A, Guimarães PP, Khan OF, Langer R.

Nat Commun. 2017 Mar 20;8:14179. doi: 10.1038/ncomms14179.


MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment.

Wilson R, Espinosa-Diez C, Kanner N, Chatterjee N, Ruhl R, Hipfinger C, Advani SJ, Li J, Khan OF, Franovic A, Weis SM, Kumar S, Coussens LM, Anderson DG, Chen CC, Cheresh DA, Anand S.

Nat Commun. 2016 Nov 25;7:13597. doi: 10.1038/ncomms13597.


Comparing Effectiveness of Active and Passive Client Follow-Up Approaches in Sustaining the Continued Use of Long Acting Reversible Contraceptives (LARC) in Rural Punjab: A Multicentre, Non-Inferiority Trial.

Hameed W, Azmat SK, Ali M, Ishaque M, Abbas G, Munroe E, Harrison R, Shamsi WH, Mustafa G, Khan OF, Ali S, Ahmed A.

PLoS One. 2016 Sep 1;11(9):e0160683. doi: 10.1371/journal.pone.0160683. eCollection 2016.


Adult patient perspectives on clinical trial result reporting: A survey of cancer patients.

Elzinga KE, Khan OF, Tang AR, Fernandez CV, Elzinga CL, Heng DY, Vickers MM, Truong TH, Tang PA.

Clin Trials. 2016 Dec;13(6):574-581. Epub 2016 Aug 23.


Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure.

Sager HB, Hulsmans M, Lavine KJ, Moreira MB, Heidt T, Courties G, Sun Y, Iwamoto Y, Tricot B, Khan OF, Dahlman JE, Borodovsky A, Fitzgerald K, Anderson DG, Weissleder R, Libby P, Swirski FK, Nahrendorf M.

Circ Res. 2016 Sep 16;119(7):853-64. doi: 10.1161/CIRCRESAHA.116.309001. Epub 2016 Jul 21.


Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose.

Chahal JS, Khan OF, Cooper CL, McPartlan JS, Tsosie JK, Tilley LD, Sidik SM, Lourido S, Langer R, Bavari S, Ploegh HL, Anderson DG.

Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):E4133-42. doi: 10.1073/pnas.1600299113. Epub 2016 Jul 5. Erratum in: Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):E5250.


RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction.

Sager HB, Dutta P, Dahlman JE, Hulsmans M, Courties G, Sun Y, Heidt T, Vinegoni C, Borodovsky A, Fitzgerald K, Wojtkiewicz GR, Iwamoto Y, Tricot B, Khan OF, Kauffman KJ, Xing Y, Shaw TE, Libby P, Langer R, Weissleder R, Swirski FK, Anderson DG, Nahrendorf M.

Sci Transl Med. 2016 Jun 8;8(342):342ra80. doi: 10.1126/scitranslmed.aaf1435.


MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation.

Papangeli I, Kim J, Maier I, Park S, Lee A, Kang Y, Tanaka K, Khan OF, Ju H, Kojima Y, Red-Horse K, Anderson DG, Siekmann AF, Chun HJ.

Nat Commun. 2016 Apr 12;7:11268. doi: 10.1038/ncomms11268.


Engaging with community-based public and private mid-level providers for promoting the use of modern contraceptive methods in rural Pakistan: results from two innovative birth spacing interventions.

Azmat SK, Hameed W, Hamza HB, Mustafa G, Ishaque M, Abbas G, Khan OF, Asghar J, Munroe E, Ali S, Hussain W, Ali S, Ahmed A, Ali M, Temmerman M.

Reprod Health. 2016 Mar 17;13:25. doi: 10.1186/s12978-016-0145-9.


Continuation rates and reasons for discontinuation of intra-uterine device in three provinces of Pakistan: results of a 24-month prospective client follow-up.

Hameed W, Azmat SK, Ishaque M, Hussain W, Munroe E, Mustafa G, Khan OF, Abbas G, Ali S, Asghar QJ, Ali S, Ahmed A, Hamza HB.

Health Res Policy Syst. 2015 Nov 25;13 Suppl 1:53. doi: 10.1186/s12961-015-0040-9.


Macrophage Notch Ligand Delta-Like 4 Promotes Vein Graft Lesion Development: Implications for the Treatment of Vein Graft Failure.

Koga JI, Nakano T, Dahlman JE, Figueiredo JL, Zhang H, Decano J, Khan OF, Niida T, Iwata H, Aster JC, Yagita H, Anderson DG, Ozaki CK, Aikawa M.

Arterioscler Thromb Vasc Biol. 2015 Nov;35(11):2343-2353. doi: 10.1161/ATVBAHA.115.305516. Epub 2015 Sep 24. Erratum in: Arterioscler Thromb Vasc Biol. 2016 Mar;36(3):e25.


Assessing predictors of contraceptive use and demand for family planning services in underserved areas of Punjab province in Pakistan: results of a cross-sectional baseline survey.

Azmat SK, Ali M, Ishaque M, Mustafa G, Hameed W, Khan OF, Abbas G, Temmerman M, Munroe E.

Reprod Health. 2015 Mar 28;12:25. doi: 10.1186/s12978-015-0016-9.


Ex vivo cytosolic delivery of functional macromolecules to immune cells.

Sharei A, Trifonova R, Jhunjhunwala S, Hartoularos GC, Eyerman AT, Lytton-Jean A, Angin M, Sharma S, Poceviciute R, Mao S, Heimann M, Liu S, Talkar T, Khan OF, Addo M, von Andrian UH, Anderson DG, Langer R, Lieberman J, Jensen KF.

PLoS One. 2015 Apr 13;10(4):e0118803. doi: 10.1371/journal.pone.0118803. eCollection 2015.


Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension.

White K, Lu Y, Annis S, Hale AE, Chau BN, Dahlman JE, Hemann C, Opotowsky AR, Vargas SO, Rosas I, Perrella MA, Osorio JC, Haley KJ, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Khan OF, Bader A, Gochuico BR, Matar M, Polach K, Johannessen NM, Prosser HM, Anderson DG, Langer R, Zweier JL, Bindoff LA, Systrom D, Waxman AB, Jin RC, Chan SY.

EMBO Mol Med. 2015 Jun;7(6):695-713. doi: 10.15252/emmm.201404511.


Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature.

Khan OF, Zaia EW, Jhunjhunwala S, Xue W, Cai W, Yun DS, Barnes CM, Dahlman JE, Dong Y, Pelet JM, Webber MJ, Tsosie JK, Jacks TE, Langer R, Anderson DG.

Nano Lett. 2015 May 13;15(5):3008-16. doi: 10.1021/nl5048972. Epub 2015 Apr 2.


Ionizable amphiphilic dendrimer-based nanomaterials with alkyl-chain-substituted amines for tunable siRNA delivery to the liver endothelium in vivo.

Khan OF, Zaia EW, Yin H, Bogorad RL, Pelet JM, Webber MJ, Zhuang I, Dahlman JE, Langer R, Anderson DG.

Angew Chem Int Ed Engl. 2014 Dec 22;53(52):14397-401. doi: 10.1002/anie.201408221. Epub 2014 Oct 29.


A perspective on the clinical translation of scaffolds for tissue engineering.

Webber MJ, Khan OF, Sydlik SA, Tang BC, Langer R.

Ann Biomed Eng. 2015 Mar;43(3):641-56. doi: 10.1007/s10439-014-1104-7. Epub 2014 Sep 9.


Small RNA combination therapy for lung cancer.

Xue W, Dahlman JE, Tammela T, Khan OF, Sood S, Dave A, Cai W, Chirino LM, Yang GR, Bronson R, Crowley DG, Sahay G, Schroeder A, Langer R, Anderson DG, Jacks T.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):E3553-61. doi: 10.1073/pnas.1412686111. Epub 2014 Aug 11.


A novel high-speed production process to create modular components for the bottom-up assembly of large-scale tissue-engineered constructs.

Khan OF, Voice DN, Leung BM, Sefton MV.

Adv Healthc Mater. 2015 Jan 7;4(1):113-20. doi: 10.1002/adhm.201400150. Epub 2014 Jun 3.


Lipid-like nanomaterials for simultaneous gene expression and silencing in vivo.

Dong Y, Eltoukhy AA, Alabi CA, Khan OF, Veiseh O, Dorkin JR, Sirirungruang S, Yin H, Tang BC, Pelet JM, Chen D, Gu Z, Xue Y, Langer R, Anderson DG.

Adv Healthc Mater. 2014 Sep;3(9):1392-7. doi: 10.1002/adhm.201400054. Epub 2014 Mar 13.


Impact of Physician's Education on Adherence to Tuberculosis Treatment for Patients of Low Socioeconomic Status in Bangladesh.

Lee S, Khan OF, Seo JH, Kim DY, Park KH, Jung SI, Chung EK, Jang HC.

Chonnam Med J. 2013 Apr;49(1):27-30. doi: 10.4068/cmj.2013.49.1.27. Epub 2013 Apr 25.


Toward an in vitro vasculature: differentiation of mesenchymal stromal cells within an endothelial cell-seeded modular construct in a microfluidic flow chamber.

Khan OF, Chamberlain MD, Sefton MV.

Tissue Eng Part A. 2012 Apr;18(7-8):744-56. doi: 10.1089/ten.TEA.2011.0058. Epub 2011 Dec 2.


Endothelialized biomaterials for tissue engineering applications in vivo.

Khan OF, Sefton MV.

Trends Biotechnol. 2011 Aug;29(8):379-87. doi: 10.1016/j.tibtech.2011.03.004. Epub 2011 May 5. Review.


Fabrication of micro-tissues using modules of collagen gel containing cells.

Chamberlain MD, Butler MJ, Ciucurel EC, Fitzpatrick LE, Khan OF, Leung BM, Lo C, Patel R, Velchinskaya A, Voice DN, Sefton MV.

J Vis Exp. 2010 Dec 13;(46). pii: 2177. doi: 10.3791/2177.


Patterning collagen/poloxamine-methacrylate hydrogels for tissue-engineering-inspired microfluidic and laser lithography applications.

Khan OF, Sefton MV.

J Biomater Sci Polym Ed. 2011;22(18):2499-514. doi: 10.1163/092050610X540693.


Endothelial cell behaviour within a microfluidic mimic of the flow channels of a modular tissue engineered construct.

Khan OF, Sefton MV.

Biomed Microdevices. 2011 Feb;13(1):69-87. doi: 10.1007/s10544-010-9472-8.


Perfusion and characterization of an endothelial cell-seeded modular tissue engineered construct formed in a microfluidic remodeling chamber.

Khan OF, Sefton MV.

Biomaterials. 2010 Nov;31(32):8254-61. doi: 10.1016/j.biomaterials.2010.07.041. Epub 2010 Aug 3.


MMP levels in the response to degradable implants in the presence of a hydroxamate-based matrix metalloproteinase sequestering biomaterial in vivo.

Khan OF, Jean-Francois J, Sefton MV.

J Biomed Mater Res A. 2010 Jun 15;93(4):1368-79. doi: 10.1002/jbm.a.32634.


Self-expense among outpatient department patients at a public hospital in Karachi, Pakistan.

Syed N, Athar R, Khan OF, Shakoor K, Qureshi H, Alam SE.

J Pak Med Assoc. 2004 May;54(5):270-1. No abstract available.


Antidiarrhoeal activity of the bark extract of Careya arborea Roxb.

Rahman MT, Khan OF, Saha S, Alimuzzaman M.

Fitoterapia. 2003 Feb;74(1-2):116-8.


A preliminary study on the analgesic activity of Grangea maderaspatana.

Ahmed M, Islam MM, Hossain CF, Khan OF.

Fitoterapia. 2001 Jun;72(5):553-4.


Prescribing pattern in acute diarrhoea in three districts in Bangladesh.

Chowdhury AK, Matin MA, Islam MA, Khan OF.

Trop Doct. 1993 Oct;23(4):165-6.


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