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Items: 18


Engineering Protein-Secreting Plasma Cells by Homology-Directed Repair in Primary Human B Cells.

Hung KL, Meitlis I, Hale M, Chen CY, Singh S, Jackson SW, Miao CH, Khan IF, Rawlings DJ, James RG.

Mol Ther. 2018 Feb 7;26(2):456-467. doi: 10.1016/j.ymthe.2017.11.012. Epub 2017 Nov 22.


"Where It Falls Apart": Barriers to Retention in HIV Care in Latino Immigrants and Migrants.

Levison JH, Bogart LM, Khan IF, Mejia D, Amaro H, Alegría M, Safren S.

AIDS Patient Care STDS. 2017 Sep;31(9):394-405. doi: 10.1089/apc.2017.0084.


High Efficiency CRISPR/Cas9-mediated Gene Editing in Primary Human T-cells Using Mutant Adenoviral E4orf6/E1b55k "Helper" Proteins.

Gwiazda KS, Grier AE, Sahni J, Burleigh SM, Martin U, Yang JG, Popp NA, Krutein MC, Khan IF, Jacoby K, Jensen MC, Rawlings DJ, Scharenberg AM.

Mol Ther. 2016 Sep 29;24(9):1570-80. doi: 10.1038/mt.2016.105. Epub 2016 May 16.


Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template.

Sather BD, Romano Ibarra GS, Sommer K, Curinga G, Hale M, Khan IF, Singh S, Song Y, Gwiazda K, Sahni J, Jarjour J, Astrakhan A, Wagner TA, Scharenberg AM, Rawlings DJ.

Sci Transl Med. 2015 Sep 30;7(307):307ra156. doi: 10.1126/scitranslmed.aac5530.


Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus.

Wang Y, Khan IF, Boissel S, Jarjour J, Pangallo J, Thyme S, Baker D, Scharenberg AM, Rawlings DJ.

Nucleic Acids Res. 2014 Jun;42(10):6463-75. doi: 10.1093/nar/gku224. Epub 2014 Mar 25.


Lack of genotoxicity due to foamy virus vector integration in human iPSCs.

Deyle DR, Khan IF, Ren G, Russell DW.

Gene Ther. 2013 Aug;20(8):868-73. doi: 10.1038/gt.2013.6. Epub 2013 Feb 7.


Normal collagen and bone production by gene-targeted human osteogenesis imperfecta iPSCs.

Deyle DR, Khan IF, Ren G, Wang PR, Kho J, Schwarze U, Russell DW.

Mol Ther. 2012 Jan;20(1):204-13. doi: 10.1038/mt.2011.209. Epub 2011 Oct 25.


AAV-mediated gene targeting methods for human cells.

Khan IF, Hirata RK, Russell DW.

Nat Protoc. 2011 Apr;6(4):482-501. doi: 10.1038/nprot.2011.301. Epub 2011 Mar 24.


Engineering of human pluripotent stem cells by AAV-mediated gene targeting.

Khan IF, Hirata RK, Wang PR, Li Y, Kho J, Nelson A, Huo Y, Zavaljevski M, Ware C, Russell DW.

Mol Ther. 2010 Jun;18(6):1192-9. doi: 10.1038/mt.2010.55. Epub 2010 Apr 20.


Inactivation of L-type calcium channels is determined by the length of the N terminus of mutant beta(1) subunits.

Jangsangthong W, Kuzmenkina E, Khan IF, Matthes J, Hullin R, Herzig S.

Pflugers Arch. 2010 Feb;459(3):399-411. doi: 10.1007/s00424-009-0738-z. Epub 2009 Oct 12.


Regulation of the human cardiac mitochondrial Ca2+ uptake by 2 different voltage-gated Ca2+ channels.

Michels G, Khan IF, Endres-Becker J, Rottlaender D, Herzig S, Ruhparwar A, Wahlers T, Hoppe UC.

Circulation. 2009 May 12;119(18):2435-43. doi: 10.1161/CIRCULATIONAHA.108.835389. Epub 2009 Apr 27.


Direct evidence for calcium conductance of hyperpolarization-activated cyclic nucleotide-gated channels and human native If at physiological calcium concentrations.

Michels G, Brandt MC, Zagidullin N, Khan IF, Larbig R, van Aaken S, Wippermann J, Hoppe UC.

Cardiovasc Res. 2008 Jun 1;78(3):466-75. doi: 10.1093/cvr/cvn032. Epub 2008 Feb 5. Erratum in: Cardiovasc Res. 2012 Sep 1;95(4):527.


K+ channel regulator KCR1 suppresses heart rhythm by modulating the pacemaker current If.

Michels G, Er F, Khan IF, Endres-Becker J, Brandt MC, Gassanov N, Johns DC, Hoppe UC.

PLoS One. 2008 Jan 30;3(1):e1511. doi: 10.1371/journal.pone.0001511. Erratum in: PLoS One. 2012;7(8): doi/10.1371/annotation/ff27c2a4-7732-4c32-88da-c412f1cced0c.


Successful treatment of canine leukocyte adhesion deficiency by foamy virus vectors.

Bauer TR Jr, Allen JM, Hai M, Tuschong LM, Khan IF, Olson EM, Adler RL, Burkholder TH, Gu YC, Russell DW, Hickstein DD.

Nat Med. 2008 Jan;14(1):93-7. Epub 2007 Dec 23.


Genetic diversity of HIV type 1 subtype C env gene sequences from India.

Khan IF, Vajpayee M, Prasad VV, Seth P.

AIDS Res Hum Retroviruses. 2007 Jul;23(7):934-40.


Mechanism of Ca(v)1.2 channel modulation by the amino terminus of cardiac beta2-subunits.

Herzig S, Khan IF, Gr√ľndemann D, Matthes J, Ludwig A, Michels G, Hoppe UC, Chaudhuri D, Schwartz A, Yue DT, Hullin R.

FASEB J. 2007 May;21(7):1527-38. Epub 2007 Feb 8.


Single-channel gating and regulation of human L-type calcium channels in cardiomyocytes of transgenic mice.

Groner F, Rubio M, Schulte-Euler P, Matthes J, Khan IF, Bodi I, Koch SE, Schwartz A, Herzig S.

Biochem Biophys Res Commun. 2004 Feb 13;314(3):878-84.


Cardiac L-type calcium channel beta-subunits expressed in human heart have differential effects on single channel characteristics.

Hullin R, Khan IF, Wirtz S, Mohacsi P, Varadi G, Schwartz A, Herzig S.

J Biol Chem. 2003 Jun 13;278(24):21623-30. Epub 2003 Feb 26.

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