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Items: 41

1.

Two modes of cis-activation of switch transcription by the IgH superenhancer.

Santos JM, Braikia FZ, Oudinet C, Dauba A, Khamlichi AA.

Proc Natl Acad Sci U S A. 2019 Jul 16;116(29):14708-14713. doi: 10.1073/pnas.1902250116. Epub 2019 Jul 2.

PMID:
31266889
2.

Developmental regulation of DNA cytosine methylation at the immunoglobulin heavy chain constant locus.

Oudinet C, Braikia FZ, Dauba A, Santos JM, Khamlichi AA.

PLoS Genet. 2019 Feb 19;15(2):e1007930. doi: 10.1371/journal.pgen.1007930. eCollection 2019 Feb.

3.

PAX5-ELN oncoprotein promotes multistep B-cell acute lymphoblastic leukemia in mice.

Jamrog L, Chemin G, Fregona V, Coster L, Pasquet M, Oudinet C, Rouquié N, Prade N, Lagarde S, Cresson C, Hébrard S, Nguyen Huu NS, Bousquet M, Quelen C, Brousset P, Mancini SJC, Delabesse E, Khamlichi AA, Gerby B, Broccardo C.

Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10357-10362. doi: 10.1073/pnas.1721678115. Epub 2018 Sep 26.

4.

Parallels between Mammalian Mechanisms of Monoallelic Gene Expression.

Khamlichi AA, Feil R.

Trends Genet. 2018 Dec;34(12):954-971. doi: 10.1016/j.tig.2018.08.005. Epub 2018 Sep 11. Review.

PMID:
30217559
5.

Duplication of a germline promoter downstream of the IgH 3' regulatory region impairs class switch recombination.

Santos JM, Braikia FZ, Oudinet C, Haddad D, Conte C, Dauba A, Khamlichi AA.

Sci Rep. 2018 Jun 15;8(1):9164. doi: 10.1038/s41598-018-27448-4.

6.

Inducible CTCF insulator delays the IgH 3' regulatory region-mediated activation of germline promoters and alters class switching.

Braikia FZ, Oudinet C, Haddad D, Oruc Z, Orlando D, Dauba A, Le Bert M, Khamlichi AA.

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):6092-6097. doi: 10.1073/pnas.1701631114. Epub 2017 May 22.

7.

Developmental Switch in the Transcriptional Activity of a Long-Range Regulatory Element.

Braikia FZ, Conte C, Moutahir M, Denizot Y, Cogné M, Khamlichi AA.

Mol Cell Biol. 2015 Oct;35(19):3370-80. doi: 10.1128/MCB.00509-15. Epub 2015 Jul 20.

8.

Complete cis Exclusion upon Duplication of the Eμ Enhancer at the Immunoglobulin Heavy Chain Locus.

Puget N, Leduc C, Oruc Z, Moutahir M, Le Bert M, Khamlichi AA.

Mol Cell Biol. 2015 Jul;35(13):2231-41.

9.

Insertion of an imprinted insulator into the IgH locus reveals developmentally regulated, transcription-dependent control of V(D)J recombination.

Puget N, Hirasawa R, Hu NS, Laviolette-Malirat N, Feil R, Khamlichi AA.

Mol Cell Biol. 2015 Feb;35(3):529-43. doi: 10.1128/MCB.00235-14. Epub 2014 Nov 17.

10.

Quantification of V(D)J recombination by real-time quantitative PCR.

Braikia FZ, Chemin G, Moutahir M, Khamlichi AA.

Immunol Lett. 2014 Nov;162(1 Pt A):119-23. doi: 10.1016/j.imlet.2014.08.002. Epub 2014 Aug 12.

PMID:
25128366
11.

Tissue-specific inactivation of HAT cofactor TRRAP reveals its essential role in B cells.

Leduc C, Chemin G, Puget N, Sawan C, Moutahir M, Herceg Z, Khamlichi AA.

Cell Cycle. 2014;13(10):1583-9. doi: 10.4161/cc.28560. Epub 2014 Mar 18.

12.

Seeking sense of antisense switch transcripts.

Haddad D, Puget N, Laviolette-Malirat N, Conte C, Khamlichi AA.

Transcription. 2011 Jul;2(4):183-188.

13.

Sense transcription through the S region is essential for immunoglobulin class switch recombination.

Haddad D, Oruc Z, Puget N, Laviolette-Malirat N, Philippe M, Carrion C, Le Bert M, Khamlichi AA.

EMBO J. 2011 Apr 20;30(8):1608-20. doi: 10.1038/emboj.2011.56. Epub 2011 Mar 4.

14.

Combined deficiency of MSH2 and Sμ region abolishes class switch recombination.

Leduc C, Haddad D, Laviolette-Malirat N, Nguyen Huu NS, Khamlichi AA.

Eur J Immunol. 2010 Oct;40(10):2925-31. doi: 10.1002/eji.201040605.

15.

Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions.

Zhang T, Franklin A, Boboila C, McQuay A, Gallagher MP, Manis JP, Khamlichi AA, Alt FW.

Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3040-5. doi: 10.1073/pnas.0915072107. Epub 2010 Feb 1. Erratum in: Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5731.

16.

Replacement of Imu-Cmu intron by NeoR gene alters Imu germ-line expression but has no effect on V(D)J recombination.

Haddad D, Dougier HL, Laviolette N, Puget N, Khamlichi AA.

Mol Immunol. 2010 Feb;47(5):961-71. doi: 10.1016/j.molimm.2009.11.024. Epub 2009 Dec 28.

PMID:
20036775
17.

S region sequence, RNA polymerase II, and histone modifications create chromatin accessibility during class switch recombination.

Wang L, Wuerffel R, Feldman S, Khamlichi AA, Kenter AL.

J Exp Med. 2009 Aug 3;206(8):1817-30. doi: 10.1084/jem.20081678. Epub 2009 Jul 13.

18.

Immunoglobulin switch mu sequence causes RNA polymerase II accumulation and reduces dA hypermutation.

Rajagopal D, Maul RW, Ghosh A, Chakraborty T, Khamlichi AA, Sen R, Gearhart PJ.

J Exp Med. 2009 Jun 8;206(6):1237-44. doi: 10.1084/jem.20082514. Epub 2009 May 11.

19.

Replacement of Igamma3 germ-line promoter by Igamma1 inhibits class-switch recombination to IgG3.

Oruc Z, Boumédiène A, Le Bert M, Khamlichi AA.

Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20484-9. Epub 2007 Dec 11.

20.

Sequence dependence of chromosomal R-loops at the immunoglobulin heavy-chain Smu class switch region.

Huang FT, Yu K, Balter BB, Selsing E, Oruc Z, Khamlichi AA, Hsieh CL, Lieber MR.

Mol Cell Biol. 2007 Aug;27(16):5921-32. Epub 2007 Jun 11.

21.

Internalization and molecular interactions of human CD21 receptor.

Tessier J, Cuvillier A, Glaudet F, Khamlichi AA.

Mol Immunol. 2007 Mar;44(9):2415-25. Epub 2006 Nov 21.

PMID:
17118449
22.

Germ line transcription in mice bearing neor gene downstream of Igamma3 exon in the Ig heavy chain locus.

Samara M, Oruc Z, Dougier HL, Essawi T, Cogné M, Khamlichi AA.

Int Immunol. 2006 Apr;18(4):581-9. Epub 2006 Feb 28.

PMID:
16507599
23.

Induction of somatic hypermutation by antigen-specific B cell receptors in the human BL2 cell line.

Glaudet F, Denis V, Cogné M, Khamlichi AA.

Eur J Immunol. 2004 Jun;34(6):1637-45.

24.

Immunoglobulin class-switch recombination in mice devoid of any S mu tandem repeat.

Khamlichi AA, Glaudet F, Oruc Z, Denis V, Le Bert M, Cogné M.

Blood. 2004 May 15;103(10):3828-36. Epub 2004 Feb 12.

PMID:
14962903
25.
26.

Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination.

Pinaud E, Khamlichi AA, Le Morvan C, Drouet M, Nalesso V, Le Bert M, Cogné M.

Immunity. 2001 Aug;15(2):187-99.

27.

Disruption of mouse polymerase zeta (Rev3) leads to embryonic lethality and impairs blastocyst development in vitro.

Bemark M, Khamlichi AA, Davies SL, Neuberger MS.

Curr Biol. 2000 Oct 5;10(19):1213-6.

28.

The 3' IgH regulatory region: a complex structure in a search for a function.

Khamlichi AA, Pinaud E, Decourt C, Chauveau C, Cogné M.

Adv Immunol. 2000;75:317-45. Review. No abstract available.

PMID:
10879288
29.
30.

Role of light chain variable region in myeloma with light chain deposition disease: evidence from an experimental model.

Khamlichi AA, Rocca A, Touchard G, Aucouturier P, Preud'homme JL, Cogné M.

Blood. 1995 Nov 15;86(10):3655-9.

PMID:
7579330
31.

Sequences of V kappa L subgroup light chains in Fanconi's syndrome. Light chain V region gene usage restriction and peculiarities in myeloma-associated Fanconi's syndrome.

Rocca A, Khamlichi AA, Touchard G, Mougenot B, Ronco P, Denoroy L, Deret S, Preud'homme JL, Aucouturier P, Cogné M.

J Immunol. 1995 Sep 15;155(6):3245-52.

PMID:
7673737
32.

Structure of abnormal heavy chains in human heavy-chain-deposition disease.

Khamlichi AA, Aucouturier P, Preud'homme JL, Cogné M.

Eur J Biochem. 1995 Apr 1;229(1):54-60.

33.

The effect of intron sequences on expression levels of Ig cDNAs.

Khamlichi AA, Rocca A, Cogné M.

Gene. 1994 Dec 15;150(2):387-90.

PMID:
7821812
34.

Monoclonal immunoglobulin deposition disease (Randall type). Relationship with structural abnormalities of immunoglobulin chains.

Preud'homme JL, Aucouturier P, Touchard G, Striker L, Khamlichi AA, Rocca A, Denoroy L, Cogné M.

Kidney Int. 1994 Oct;46(4):965-72. Review. No abstract available.

35.

Monoclonal immunoglobulin deposition disease: a review of immunoglobulin chain alterations.

Preud'homme JL, Aucouturier P, Touchard G, Khamlichi AA, Rocca A, Denoroy L, Cogné M.

Int J Immunopharmacol. 1994 May-Jun;16(5-6):425-31. Review.

PMID:
7927989
36.

Brief report: heavy-chain deposition disease.

Aucouturier P, Khamlichi AA, Touchard G, Justrabo E, Cogne M, Chauffert B, Martin F, Preud'homme JL.

N Engl J Med. 1993 Nov 4;329(19):1389-93. No abstract available.

37.

Monoclonal Ig L chain and L chain V domain fragment crystallization in myeloma-associated Fanconi's syndrome.

Aucouturier P, Bauwens M, Khamlichi AA, Denoroy L, Spinelli S, Touchard G, Preud'homme JL, Cogné M.

J Immunol. 1993 Apr 15;150(8 Pt 1):3561-8.

PMID:
8468490
38.

Primary structure of a variable region of the V kappa I subgroup (ISE) in light chain deposition disease.

Rocca A, Khamlichi AA, Aucouturier P, Noël LH, Denoroy L, Preud'homme JL, Cogné M.

Clin Exp Immunol. 1993 Mar;91(3):506-9.

39.

Complementary DNA sequence of human amyloidogenic immunoglobulin light-chain precursors.

Aucouturier P, Khamlichi AA, Preud'homme JL, Bauwens M, Touchard G, Cogné M.

Biochem J. 1992 Jul 1;285 ( Pt 1):149-52.

40.

Structurally abnormal immunoglobulins in human immunoproliferative disorders.

Cogné M, Silvain C, Khamlichi AA, Preud'homme JL.

Blood. 1992 May 1;79(9):2181-95. Review. No abstract available.

PMID:
1571535
41.

Primary structure of a monoclonal kappa chain in myeloma with light chain deposition disease.

Khamlichi AA, Aucouturier P, Silvain C, Bauwens M, Touchard G, Preud'homme JL, Nau F, Cogné M.

Clin Exp Immunol. 1992 Jan;87(1):122-6.

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