Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 51

1.

Lipid Nanoparticles for Cell-Specific in Vivo Targeted Delivery of Nucleic Acids.

Khalil IA, Younis MA, Kimura S, Harashima H.

Biol Pharm Bull. 2020;43(4):584-595. doi: 10.1248/bpb.b19-00743.

2.

Strangulated Internal Hernia through Appendicular Tourniquet/Ring: Unusual Cause of Intestinal Obstruction.

Ali SM, Khalil IA, Musthafa S, Shah AA, Aftab Z, Al-Mudares S.

Am J Case Rep. 2020 Feb 14;21:e920384. doi: 10.12659/AJCR.920384.

3.

Epidemiology of injuries from fire, heat and hot substances: global, regional and national morbidity and mortality estimates from the Global Burden of Disease 2017 study.

James SL, Lucchesi LR, Bisignano C, Castle CD, Dingels ZV, Fox JT, Hamilton EB, Henry NJ, McCracken D, Roberts NLS, Sylte DO, Ahmadi A, Ahmed MB, Alahdab F, Alipour V, Andualem Z, Antonio CAT, Arabloo J, Badiye AD, Bagherzadeh M, Banstola A, Bärnighausen TW, Barzegar A, Bayati M, Bhaumik S, Bijani A, Bukhman G, Carvalho F, Crowe CS, Dalal K, Daryani A, Nasab MD, Do HT, Do HP, Endries AY, Fernandes E, Filip I, Fischer F, Fukumoto T, Gebremedhin KBB, Gebremeskel GG, Gilani SA, Haagsma JA, Hamidi S, Hostiuc S, Househ M, Igumbor EU, Ilesanmi OS, Irvani SSN, Jayatilleke AU, Kahsay A, Kapoor N, Kasaeian A, Khader YS, Khalil IA, Khan EA, Khazaee-Pool M, Kokubo Y, Lopez AD, Madadin M, Majdan M, Maled V, Malekzadeh R, Manafi N, Manafi A, Mangalam S, Massenburg BB, Meles HG, Menezes RG, Meretoja TJ, Miazgowski B, Miller TR, Mohammadian-Hafshejani A, Mohammadpourhodki R, Morrison SD, Negoi I, Nguyen TH, Nguyen SH, Nguyen CT, Nixon MR, Olagunju AT, Olagunju TO, Padubidri JR, Polinder S, Rabiee N, Rabiee M, Radfar A, Rahimi-Movaghar V, Rawaf S, Rawaf DL, Rezapour A, Rickard J, Roro EM, Roy N, Safari-Faramani R, Salamati P, Samy AM, Satpathy M, Sawhney M, Schwebel DC, Senthilkumaran S, Sepanlou SG, Shigematsu M, Soheili A, Stokes MA, Tohidinik HR, Tran BX, Valdez PR, Wijeratne T, Yisma E, Zaidi Z, Zamani M, Zhang ZJ, Hay SI, Mokdad AH.

Inj Prev. 2019 Dec 18. pii: injuryprev-2019-043299. doi: 10.1136/injuryprev-2019-043299. [Epub ahead of print]

4.

Fortified hyperbranched PEGylated chitosan-based nano-in-micro composites for treatment of multiple bacterial infections.

Abd Elsalam EA, Shabaiek HF, Abdelaziz MM, Khalil IA, El-Sherbiny IM.

Int J Biol Macromol. 2020 Apr 1;148:1201-1210. doi: 10.1016/j.ijbiomac.2019.10.164. Epub 2019 Nov 18.

PMID:
31751691
5.

Identifying residual hotspots and mapping lower respiratory infection morbidity and mortality in African children from 2000 to 2017.

Reiner RC, Welgan CA, Casey DC, Troeger CE, Baumann MM, Nguyen QP, Swartz SJ, Blacker BF, Deshpande A, Mosser JF, Osgood-Zimmerman AE, Earl L, Marczak LB, Munro SB, Miller-Petrie MK, Rodgers Kemp G, Frostad J, Wiens KE, Lindstedt PA, Pigott DM, Dwyer-Lindgren L, Ross JM, Burstein R, Graetz N, Rao PC, Khalil IA, Davis Weaver N, Ray SE, Davis I, Farag T, Brady OJ, Kraemer MUG, Smith DL, Bhatt S, Weiss DJ, Gething PW, Kassebaum NJ, Mokdad AH, Murray CJL, Hay SI.

Nat Microbiol. 2019 Dec;4(12):2310-2318. doi: 10.1038/s41564-019-0562-y. Epub 2019 Sep 30.

6.

Spleen selective enhancement of transfection activities of plasmid DNA driven by octaarginine and an ionizable lipid and its implications for cancer immunization.

Kimura S, Khalil IA, Elewa YHA, Harashima H.

J Control Release. 2019 Nov 10;313:70-79. doi: 10.1016/j.jconrel.2019.09.009. Epub 2019 Sep 14.

PMID:
31526828
7.

Recent advances in the targeting of systemically administered non-viral gene delivery systems.

Khalil IA, Sato Y, Harashima H.

Expert Opin Drug Deliv. 2019 Oct;16(10):1037-1050. doi: 10.1080/17425247.2019.1656196. Epub 2019 Aug 21. Review.

PMID:
31432700
8.

Multifunctional prosthetic polyester-based hybrid mesh for repairing of abdominal wall hernias and defects.

Shokry MM, Khalil IA, El-Kasapy A, Osman A, Mostafa A, Salah M, El-Sherbiny IM.

Carbohydr Polym. 2019 Nov 1;223:115027. doi: 10.1016/j.carbpol.2019.115027. Epub 2019 Jul 5.

PMID:
31426976
9.

A Multifunctional Lipid-Based Nanodevice for the Highly Specific Codelivery of Sorafenib and Midkine siRNA to Hepatic Cancer Cells.

Younis MA, Khalil IA, Abd Elwakil MM, Harashima H.

Mol Pharm. 2019 Sep 3;16(9):4031-4044. doi: 10.1021/acs.molpharmaceut.9b00738. Epub 2019 Aug 23.

PMID:
31403802
10.

Sandwich-Like Nanofibrous Scaffolds for Bone Tissue Regeneration.

Yahia S, Khalil IA, El-Sherbiny IM.

ACS Appl Mater Interfaces. 2019 Aug 14;11(32):28610-28620. doi: 10.1021/acsami.9b06359. Epub 2019 Aug 5.

PMID:
31328910
11.

Innovative nanotechnologies for enhancing nucleic acids/gene therapy: Controlling intracellular trafficking to targeted biodistribution.

Nakamura T, Yamada Y, Sato Y, Khalil IA, Harashima H.

Biomaterials. 2019 Oct;218:119329. doi: 10.1016/j.biomaterials.2019.119329. Epub 2019 Jul 4. Review.

PMID:
31306827
12.

Phenytoin/sildenafil loaded poly(lactic acid) bilayer nanofibrous scaffolds for efficient orthopedics regeneration.

Ali IH, Khalil IA, El-Sherbiny IM.

Int J Biol Macromol. 2019 Sep 1;136:154-164. doi: 10.1016/j.ijbiomac.2019.06.048. Epub 2019 Jun 10.

PMID:
31195040
13.

A study of the endocytosis mechanism and transendothelial activity of lung-targeted GALA-modified liposomes.

Santiwarangkool S, Akita H, Khalil IA, Abd Elwakil MM, Sato Y, Kusumoto K, Harashima H.

J Control Release. 2019 Aug 10;307:55-63. doi: 10.1016/j.jconrel.2019.06.009. Epub 2019 Jun 8.

PMID:
31185231
14.

Estimating health-loss due to enteric pathogens: importance and challenges.

Troeger C, Khalil IA, Reiner RC Jr.

Lancet Glob Health. 2019 Mar;7(3):e284-e285. doi: 10.1016/S2214-109X(19)30017-8. No abstract available.

15.

Noninvasive biodegradable nanoparticles-in-nanofibers single-dose ocular insert: in vitro, ex vivo and in vivo evaluation.

Khalil IA, Ali IH, El-Sherbiny IM.

Nanomedicine (Lond). 2019 Jan;14(1):33-55. doi: 10.2217/nnm-2018-0297. Epub 2018 Dec 13.

PMID:
30543484
16.

Hybrid nanocarrier system for guiding and augmenting simvastatin cytotoxic activity against prostate cancer.

Sedki M, Khalil IA, El-Sherbiny IM.

Artif Cells Nanomed Biotechnol. 2018;46(sup3):S641-S650. doi: 10.1080/21691401.2018.1505743. Epub 2018 Oct 8.

PMID:
30295086
17.

Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990-2016.

Khalil IA, Troeger C, Blacker BF, Rao PC, Brown A, Atherly DE, Brewer TG, Engmann CM, Houpt ER, Kang G, Kotloff KL, Levine MM, Luby SP, MacLennan CA, Pan WK, Pavlinac PB, Platts-Mills JA, Qadri F, Riddle MS, Ryan ET, Shoultz DA, Steele AD, Walson JL, Sanders JW, Mokdad AH, Murray CJL, Hay SI, Reiner RC Jr.

Lancet Infect Dis. 2018 Nov;18(11):1229-1240. doi: 10.1016/S1473-3099(18)30475-4. Epub 2018 Sep 25. Erratum in: Lancet Infect Dis. 2018 Oct 30;:.

18.

Variation in Childhood Diarrheal Morbidity and Mortality in Africa, 2000-2015.

Reiner RC Jr, Graetz N, Casey DC, Troeger C, Garcia GM, Mosser JF, Deshpande A, Swartz SJ, Ray SE, Blacker BF, Rao PC, Osgood-Zimmerman A, Burstein R, Pigott DM, Davis IM, Letourneau ID, Earl L, Ross JM, Khalil IA, Farag TH, Brady OJ, Kraemer MUG, Smith DL, Bhatt S, Weiss DJ, Gething PW, Kassebaum NJ, Mokdad AH, Murray CJL, Hay SI.

N Engl J Med. 2018 Sep 20;379(12):1128-1138. doi: 10.1056/NEJMoa1716766.

19.

Optimization of siRNA delivery to target sites: issues and future directions.

Khalil IA, Yamada Y, Harashima H.

Expert Opin Drug Deliv. 2018 Nov;15(11):1053-1065. doi: 10.1080/17425247.2018.1520836. Epub 2018 Sep 25. Review.

PMID:
30198792
20.

Global Mortality From Firearms, 1990-2016.

Global Burden of Disease 2016 Injury Collaborators, Naghavi M, Marczak LB, Kutz M, Shackelford KA, Arora M, Miller-Petrie M, Aichour MTE, Akseer N, Al-Raddadi RM, Alam K, Alghnam SA, Antonio CAT, Aremu O, Arora A, Asadi-Lari M, Assadi R, Atey TM, Avila-Burgos L, Awasthi A, Ayala Quintanilla BP, Barker-Collo SL, Bärnighausen TW, Bazargan-Hejazi S, Behzadifar M, Behzadifar M, Bennett JR, Bhalla A, Bhutta ZA, Bilal AI, Borges G, Borschmann R, Brazinova A, Campuzano Rincon JC, Carvalho F, Castañeda-Orjuela CA, Dandona L, Dandona R, Dargan PI, De Leo D, Dharmaratne SD, Ding EL, Phuc Do H, Doku DT, Doyle KE, Driscoll TR, Edessa D, El-Khatib Z, Endries AY, Esteghamati A, Faro A, Farzadfar F, Feigin VL, Fischer F, Foreman KJ, Franklin RC, Fullman N, Futran ND, Gebrehiwot TT, Gutiérrez RA, Hafezi-Nejad N, Haghparast Bidgoli H, Hailu GB, Haro JM, Hassen HY, Hawley C, Hendrie D, Híjar M, Hu G, Ilesanmi OS, Jakovljevic M, James SL, Jayaraman S, Jonas JB, Kahsay A, Kasaeian A, Keiyoro PN, Khader Y, Khalil IA, Khang YH, Khubchandani J, Ahmad Kiadaliri A, Kieling C, Kim YJ, Kosen S, Krohn KJ, Kumar GA, Lami FH, Lansingh VC, Larson HJ, Linn S, Lunevicius R, Magdy Abd El Razek H, Magdy Abd El Razek M, Malekzadeh R, Carvalho Malta D, Mason-Jones AJ, Matzopoulos R, Memiah PTN, Mendoza W, Meretoja TJ, Mezgebe HB, Miller TR, Mohammed S, Moradi-Lakeh M, Mori R, Nand D, Tat Nguyen C, Le Nguyen Q, Ningrum DNA, Akpojene Ogbo F, Olagunju AT, Patton GC, Phillips MR, Polinder S, Pourmalek F, Qorbani M, Rahimi-Movaghar A, Rahimi-Movaghar V, Rahman M, Rai RK, Ranabhat CL, Rawaf DL, Rawaf S, Rowhani-Rahbar A, Safdarian M, Safiri S, Sagar R, Salama JS, Sanabria J, Santric Milicevic MM, Sarmiento-Suárez R, Sartorius B, Satpathy M, Schwebel DC, Seedat S, Sepanlou SG, Shaikh MA, Sharew NT, Shiue I, Singh JA, Sisay M, Skirbekk V, Soares Filho AM, Stein DJ, Stokes MA, Sufiyan MB, Swaroop M, Sykes BL, Tabarés-Seisdedos R, Tadese F, Tran BX, Thanh Tran T, Ukwaja KN, Vasankari TJ, Vlassov V, Werdecker A, Ye P, Yip P, Yonemoto N, Younis MZ, Zaidi Z, El Sayed Zaki M, Hay SI, Lim SS, Lopez AD, Mokdad AH, Vos T, Murray CJL.

JAMA. 2018 Aug 28;320(8):792-814. doi: 10.1001/jama.2018.10060. Erratum in: JAMA. 2018 Sep 25;320(12):1288.

21.

Rotavirus Vaccination and the Global Burden of Rotavirus Diarrhea Among Children Younger Than 5 Years.

Troeger C, Khalil IA, Rao PC, Cao S, Blacker BF, Ahmed T, Armah G, Bines JE, Brewer TG, Colombara DV, Kang G, Kirkpatrick BD, Kirkwood CD, Mwenda JM, Parashar UD, Petri WA Jr, Riddle MS, Steele AD, Thompson RL, Walson JL, Sanders JW, Mokdad AH, Murray CJL, Hay SI, Reiner RC Jr.

JAMA Pediatr. 2018 Oct 1;172(10):958-965. doi: 10.1001/jamapediatrics.2018.1960.

22.

Morbidity, mortality, and long-term consequences associated with diarrhoea from Cryptosporidium infection in children younger than 5 years: a meta-analyses study.

Khalil IA, Troeger C, Rao PC, Blacker BF, Brown A, Brewer TG, Colombara DV, De Hostos EL, Engmann C, Guerrant RL, Haque R, Houpt ER, Kang G, Korpe PS, Kotloff KL, Lima AAM, Petri WA Jr, Platts-Mills JA, Shoultz DA, Forouzanfar MH, Hay SI, Reiner RC Jr, Mokdad AH.

Lancet Glob Health. 2018 Jul;6(7):e758-e768. doi: 10.1016/S2214-109X(18)30283-3.

23.

Development of core-shell nanocarrier system for augmenting piperine cytotoxic activity against human brain cancer cell line.

Sedeky AS, Khalil IA, Hefnawy A, El-Sherbiny IM.

Eur J Pharm Sci. 2018 Jun 15;118:103-112. doi: 10.1016/j.ejps.2018.03.030. Epub 2018 Mar 27.

PMID:
29597041
24.

Synergism between a cell penetrating peptide and a pH-sensitive cationic lipid in efficient gene delivery based on double-coated nanoparticles.

Khalil IA, Kimura S, Sato Y, Harashima H.

J Control Release. 2018 Apr 10;275:107-116. doi: 10.1016/j.jconrel.2018.02.016. Epub 2018 Feb 13.

25.

Global disability-adjusted life-year estimates of long-term health burden and undernutrition attributable to diarrhoeal diseases in children younger than 5 years.

Troeger C, Colombara DV, Rao PC, Khalil IA, Brown A, Brewer TG, Guerrant RL, Houpt ER, Kotloff KL, Misra K, Petri WA Jr, Platts-Mills J, Riddle MS, Swartz SJ, Forouzanfar MH, Reiner RC Jr, Hay SI, Mokdad AH.

Lancet Glob Health. 2018 Mar;6(3):e255-e269. doi: 10.1016/S2214-109X(18)30045-7.

26.

An efficient PEGylated gene delivery system with improved targeting: Synergism between octaarginine and a fusogenic peptide.

Khalil IA, Harashima H.

Int J Pharm. 2018 Mar 1;538(1-2):179-187. doi: 10.1016/j.ijpharm.2018.01.007. Epub 2018 Jan 16.

27.

Facile development of nanocomplex-in-nanoparticles for enhanced loading and selective delivery of doxorubicin to brain.

Hefnawy A, Khalil IA, El-Sherbiny IM.

Nanomedicine (Lond). 2017 Dec;12(24):2737-2761. doi: 10.2217/nnm-2017-0243. Epub 2017 Nov 14.

PMID:
29135325
28.

Chitosan-Coated Cinnamon/Oregano-Loaded Solid Lipid Nanoparticles to Augment 5-Fluorouracil Cytotoxicity for Colorectal Cancer: Extract Standardization, Nanoparticle Optimization, and Cytotoxicity Evaluation.

Kamel KM, Khalil IA, Rateb ME, Elgendy H, Elhawary S.

J Agric Food Chem. 2017 Sep 13;65(36):7966-7981. doi: 10.1021/acs.jafc.7b03093. Epub 2017 Aug 29.

PMID:
28813148
29.

Sertaconazole nitrate loaded nanovesicular systems for targeting skin fungal infection: In-vitro, ex-vivo and in-vivo evaluation.

Abdellatif MM, Khalil IA, Khalil MAF.

Int J Pharm. 2017 Jul 15;527(1-2):1-11. doi: 10.1016/j.ijpharm.2017.05.029. Epub 2017 May 15.

PMID:
28522423
30.

Chitosan-based nano-in-microparticle carriers for enhanced oral delivery and anticancer activity of propolis.

Elbaz NM, Khalil IA, Abd-Rabou AA, El-Sherbiny IM.

Int J Biol Macromol. 2016 Nov;92:254-269. doi: 10.1016/j.ijbiomac.2016.07.024. Epub 2016 Jul 7.

PMID:
27397719
31.

Single-Dose Electrospun Nanoparticles-in-Nanofibers Wound Dressings with Enhanced Epithelialization, Collagen Deposition, and Granulation Properties.

Ali IH, Khalil IA, El-Sherbiny IM.

ACS Appl Mater Interfaces. 2016 Jun 15;8(23):14453-69. doi: 10.1021/acsami.6b04369. Epub 2016 Jun 1.

PMID:
27215336
32.

A new combination formula for treatment of fungal keratitis: an experimental study.

El-Mofty HM, Abdelhakim MA, El-Miligi MF, El-Nabarawi MA, Khalil IA.

J Ophthalmol. 2014;2014:173298. doi: 10.1155/2014/173298. Epub 2014 Apr 29.

33.

Octaarginine- and pH sensitive fusogenic peptide-modified nanoparticles for liver gene delivery.

Khalil IA, Hayashi Y, Mizuno R, Harashima H.

J Control Release. 2011 Dec 20;156(3):374-80. doi: 10.1016/j.jconrel.2011.08.012. Epub 2011 Aug 12.

PMID:
21864599
34.

Cell penetrating peptide-mediated systemic siRNA delivery to the liver.

Hayashi Y, Yamauchi J, Khalil IA, Kajimoto K, Akita H, Harashima H.

Int J Pharm. 2011 Oct 31;419(1-2):308-13. doi: 10.1016/j.ijpharm.2011.07.038. Epub 2011 Jul 30.

35.

Novel lipidated sorbitol-based molecular transporters for non-viral gene delivery.

Higashi T, Khalil IA, Maiti KK, Lee WS, Akita H, Harashima H, Chung SK.

J Control Release. 2009 Jun 5;136(2):140-7. doi: 10.1016/j.jconrel.2009.01.024. Epub 2009 Feb 7.

36.

Multi-layered nanoparticles for penetrating the endosome and nuclear membrane via a step-wise membrane fusion process.

Akita H, Kudo A, Minoura A, Yamaguti M, Khalil IA, Moriguchi R, Masuda T, Danev R, Nagayama K, Kogure K, Harashima H.

Biomaterials. 2009 May;30(15):2940-9. doi: 10.1016/j.biomaterials.2009.02.009. Epub 2009 Mar 4.

PMID:
19261326
37.

Octaarginine- and octalysine-modified nanoparticles have different modes of endosomal escape.

El-Sayed A, Khalil IA, Kogure K, Futaki S, Harashima H.

J Biol Chem. 2008 Aug 22;283(34):23450-61. doi: 10.1074/jbc.M709387200. Epub 2008 Jun 11.

38.

Octaarginine-modified liposomes: enhanced cellular uptake and controlled intracellular trafficking.

Khalil IA, Kogure K, Futaki S, Harashima H.

Int J Pharm. 2008 Apr 16;354(1-2):39-48. doi: 10.1016/j.ijpharm.2007.12.003. Epub 2007 Dec 14. Review.

PMID:
18242018
39.

Epidemiology and hazards of student labour in Mansoura, Egypt.

El-Gilany AH, Khalil IA, El-Wehady A.

East Mediterr Health J. 2007 Mar-Apr;13(2):347-63.

40.

Octaarginine-modified multifunctional envelope-type nanoparticles for gene delivery.

Khalil IA, Kogure K, Futaki S, Hama S, Akita H, Ueno M, Kishida H, Kudoh M, Mishina Y, Kataoka K, Yamada M, Harashima H.

Gene Ther. 2007 Apr;14(8):682-9. Epub 2007 Feb 1.

41.

Positively charged polyethylenimines enhance nasal absorption of the negatively charged drug, low molecular weight heparin.

Yang T, Hussain A, Bai S, Khalil IA, Harashima H, Ahsan F.

J Control Release. 2006 Oct 27;115(3):289-97. Epub 2006 Aug 30.

42.

Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery.

Khalil IA, Kogure K, Akita H, Harashima H.

Pharmacol Rev. 2006 Mar;58(1):32-45. Review.

PMID:
16507881
43.

High density of octaarginine stimulates macropinocytosis leading to efficient intracellular trafficking for gene expression.

Khalil IA, Kogure K, Futaki S, Harashima H.

J Biol Chem. 2006 Feb 10;281(6):3544-51. Epub 2005 Dec 2.

44.

Pharmacokinetic analysis of the tissue distribution of octaarginine modified liposomes in mice.

Mudhakir D, Akita H, Khalil IA, Futaki S, Harashima H.

Drug Metab Pharmacokinet. 2005 Aug;20(4):275-81.

46.

Mechanism of improved gene transfer by the N-terminal stearylation of octaarginine: enhanced cellular association by hydrophobic core formation.

Khalil IA, Futaki S, Niwa M, Baba Y, Kaji N, Kamiya H, Harashima H.

Gene Ther. 2004 Apr;11(7):636-44.

PMID:
14973542
47.

Prevalence of HBsAg among the non cauterized groups of blood donors.

Khalil IA, Elsheikh FS, Phrykian J, Phrykian S, Mitchell R.

East Afr Med J. 1996 Nov;73(11):717-9.

PMID:
8997860
48.

Blood group distribution in Sudan.

Khalil IA, Phrykian S, Farr AD.

Gene Geogr. 1989 Apr;3(1):7-10.

PMID:
2518630
49.
50.

Brucella antibodies in Sudanese blood donors.

Khalil IA, Phkrykian S, Farr AD.

Med Lab Sci. 1988 Oct;45(4):312-4. No abstract available.

PMID:
3268716

Supplemental Content

Loading ...
Support Center