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Items: 8

1.

Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ.

Erami Z, Khalil BD, Salloum G, Yao Y, LoPiccolo J, Shymanets A, Nürnberg B, Bresnick AR, Backer JM.

Biochem J. 2017 Nov 16;474(23):3903-3914. doi: 10.1042/BCJ20170279.

PMID:
29046393
2.

GPCR Signaling Mediates Tumor Metastasis via PI3Kβ.

Khalil BD, Hsueh C, Cao Y, Abi Saab WF, Wang Y, Condeelis JS, Bresnick AR, Backer JM.

Cancer Res. 2016 May 15;76(10):2944-53. doi: 10.1158/0008-5472.CAN-15-1675. Epub 2016 Mar 24.

3.

The regulation of RhoA at focal adhesions by StarD13 is important for astrocytoma cell motility.

Khalil BD, Hanna S, Saykali BA, El-Sitt S, Nasrallah A, Marston D, El-Sabban M, Hahn KM, Symons M, El-Sibai M.

Exp Cell Res. 2014 Feb 15;321(2):109-22. doi: 10.1016/j.yexcr.2013.11.023. Epub 2013 Dec 10.

4.

Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs).

Vadas O, Dbouk HA, Shymanets A, Perisic O, Burke JE, Abi Saab WF, Khalil BD, Harteneck C, Bresnick AR, Nürnberg B, Backer JM, Williams RL.

Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):18862-7. doi: 10.1073/pnas.1304801110. Epub 2013 Nov 4.

5.

Characterization of a tumor-associated activating mutation of the p110β PI 3-kinase.

Dbouk HA, Khalil BD, Wu H, Shymanets A, Nürnberg B, Backer JM.

PLoS One. 2013 May 29;8(5):e63833. doi: 10.1371/journal.pone.0063833. Print 2013.

6.

G protein-coupled receptor-mediated activation of p110β by Gβγ is required for cellular transformation and invasiveness.

Dbouk HA, Vadas O, Shymanets A, Burke JE, Salamon RS, Khalil BD, Barrett MO, Waldo GL, Surve C, Hsueh C, Perisic O, Harteneck C, Shepherd PR, Harden TK, Smrcka AV, Taussig R, Bresnick AR, Nürnberg B, Williams RL, Backer JM.

Sci Signal. 2012 Dec 4;5(253):ra89. doi: 10.1126/scisignal.2003264.

7.

DLC2/StarD13 plays a role of a tumor suppressor in astrocytoma.

El-Sitt S, Khalil BD, Hanna S, El-Sabban M, Fakhreddine N, El-Sibai M.

Oncol Rep. 2012 Aug;28(2):511-8. doi: 10.3892/or.2012.1819. Epub 2012 May 17.

PMID:
22614672
8.

Rho GTPases in primary brain tumor malignancy and invasion.

Khalil BD, El-Sibai M.

J Neurooncol. 2012 Jul;108(3):333-9. doi: 10.1007/s11060-012-0866-8. Epub 2012 Apr 19. Review.

PMID:
22528793

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