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Items: 1 to 50 of 222

1.

N10 -carbonyl-substituted phenothiazines inhibiting lipid peroxidation and associated nitric oxide consumption powerfully protect brain tissue against oxidative stress.

Keynes RG, Karchevskaya A, Riddall D, Griffiths CH, Bellamy TC, Chan AWE, Selwood DL, Garthwaite J.

Chem Biol Drug Des. 2019 Sep;94(3):1680-1693. doi: 10.1111/cbdd.13572. Epub 2019 Jun 12.

2.

Identification of the extracellular matrix protein Fibulin-2 as a regulator of spinal nerve organization.

Schaeffer J, Tannahill D, Cioni JM, Rowlands D, Keynes R.

Dev Biol. 2018 Oct 1;442(1):101-114. doi: 10.1016/j.ydbio.2018.06.014. Epub 2018 Jun 23.

3.

Segmentation of the chick central and peripheral nervous systems.

Keynes R, Cook G.

Int J Dev Biol. 2018;62(1-2-3):177-182. doi: 10.1387/ijdb.170297rk. Review.

4.

Trafficking and processing of bacterial proteins by mammalian cells: Insights from chondroitinase ABC.

Muir E, Raza M, Ellis C, Burnside E, Love F, Heller S, Elliot M, Daniell E, Dasgupta D, Alves N, Day P, Fawcett J, Keynes R.

PLoS One. 2017 Nov 9;12(11):e0186759. doi: 10.1371/journal.pone.0186759. eCollection 2017.

5.

Patterning spinal nerves and vertebral bones.

Keynes R.

J Anat. 2018 Apr;232(4):534-539. doi: 10.1111/joa.12714. Epub 2017 Oct 24. Review.

PMID:
29063597
6.

Building the backbone: the development and evolution of vertebral patterning.

Fleming A, Kishida MG, Kimmel CB, Keynes RJ.

Development. 2015 May 15;142(10):1733-44. doi: 10.1242/dev.118950. Review.

7.

Growth cone collapse assay.

Cook GM, Jareonsettasin P, Keynes RJ.

Methods Mol Biol. 2014;1162:73-83. doi: 10.1007/978-1-4939-0777-9_6.

PMID:
24838959
8.

AAV vector-mediated secretion of chondroitinase provides a sensitive tracer for axonal arborisations.

Alves JN, Muir EM, Andrews MR, Ward A, Michelmore N, Dasgupta D, Verhaagen J, Moloney EB, Keynes RJ, Fawcett JW, Rogers JH.

J Neurosci Methods. 2014 Apr 30;227:107-20. doi: 10.1016/j.jneumeth.2014.02.010. Epub 2014 Feb 28.

PMID:
24583077
9.

Protein synthesis dependence of growth cone collapse induced by different Nogo-A-domains.

Manns R, Schmandke A, Schmandke A, Jareonsettasin P, Cook G, Schwab ME, Holt C, Keynes R.

PLoS One. 2014 Jan 29;9(1):e86820. doi: 10.1371/journal.pone.0086820. eCollection 2014.

10.

Differing semaphorin 3A concentrations trigger distinct signaling mechanisms in growth cone collapse.

Manns RP, Cook GM, Holt CE, Keynes RJ.

J Neurosci. 2012 Jun 20;32(25):8554-9. doi: 10.1523/JNEUROSCI.5964-11.2012.

11.

The generation of vertebral segmental patterning in the chick embryo.

Senthinathan B, Sousa C, Tannahill D, Keynes R.

J Anat. 2012 Jun;220(6):591-602. doi: 10.1111/j.1469-7580.2012.01497.x. Epub 2012 Mar 28.

12.

Lentiviral vectors express chondroitinase ABC in cortical projections and promote sprouting of injured corticospinal axons.

Zhao RR, Muir EM, Alves JN, Rickman H, Allan AY, Kwok JC, Roet KC, Verhaagen J, Schneider BL, Bensadoun JC, Ahmed SG, Yáñez-Muñoz RJ, Keynes RJ, Fawcett JW, Rogers JH.

J Neurosci Methods. 2011 Sep 30;201(1):228-38. doi: 10.1016/j.jneumeth.2011.08.003. Epub 2011 Aug 9.

13.

Modification of N-glycosylation sites allows secretion of bacterial chondroitinase ABC from mammalian cells.

Muir EM, Fyfe I, Gardiner S, Li L, Warren P, Fawcett JW, Keynes RJ, Rogers JH.

J Biotechnol. 2010 Jan 15;145(2):103-10. doi: 10.1016/j.jbiotec.2009.11.002. Epub 2009 Nov 10.

14.
15.

Cytochrome P450 oxidoreductase participates in nitric oxide consumption by rat brain.

Hall CN, Keynes RG, Garthwaite J.

Biochem J. 2009 Apr 15;419(2):411-8. doi: 10.1042/BJ20082419.

16.

Analysis of the action of euxanthone, a plant-derived compound that stimulates neurite outgrowth.

Naidu M, Kuan CY, Lo WL, Raza M, Tolkovsky A, Mak NK, Wong RN, Keynes R.

Neuroscience. 2007 Sep 21;148(4):915-24. Epub 2007 Aug 1.

PMID:
17825492
17.

Neuroinhibitory molecules in Alzheimer's disease.

Larner AJ, Keynes RJ.

J Alzheimers Dis. 2006 Sep;10(1):75-80. Review.

PMID:
16988484
18.
19.

Role of morphogens in brain growth.

Tannahill D, Harris LW, Keynes R.

J Neurobiol. 2005 Sep 15;64(4):367-75. Review.

20.

The Functioning of the Giant Nerve Fibres of the Squid. 1938 - J.Z. and the discovery of squid giant nerve fibres.

Young JZ, Keynes R.

J Exp Biol. 2005 Jan;208(Pt 2):179-80. No abstract available.

21.

Nitric oxide consumption through lipid peroxidation in brain cell suspensions and homogenates.

Keynes RG, Griffiths CH, Hall C, Garthwaite J.

Biochem J. 2005 May 1;387(Pt 3):685-94.

22.

Tsukushi functions as an organizer inducer by inhibition of BMP activity in cooperation with chordin.

Ohta K, Lupo G, Kuriyama S, Keynes R, Holt CE, Harris WA, Tanaka H, Ohnuma SI.

Dev Cell. 2004 Sep;7(3):347-358. doi: 10.1016/j.devcel.2004.08.014.

23.

Somite polarity and segmental patterning of the peripheral nervous system.

Kuan CY, Tannahill D, Cook GM, Keynes RJ.

Mech Dev. 2004 Sep;121(9):1055-68. Review.

24.

Nitric oxide and its role in ischaemic brain injury.

Keynes RG, Garthwaite J.

Curr Mol Med. 2004 Mar;4(2):179-91. Review.

PMID:
15032712
25.
26.

A central role for the notochord in vertebral patterning.

Fleming A, Keynes R, Tannahill D.

Development. 2004 Feb;131(4):873-80. Epub 2004 Jan 21.

27.

Founding editorial: embryology--an integrated approach.

Richardson M, Keynes R, Mabee P, Selwood L.

ScientificWorldJournal. 2001 Oct 26;1:602-4.

28.

Molecular analysis of axon repulsion by the notochord.

Anderson CN, Ohta K, Quick MM, Fleming A, Keynes R, Tannahill D.

Development. 2003 Mar;130(6):1123-33.

29.

Superoxide-dependent consumption of nitric oxide in biological media may confound in vitro experiments.

Keynes RG, Griffiths C, Garthwaite J.

Biochem J. 2003 Jan 15;369(Pt 2):399-406.

30.

A critical role for sonic hedgehog signaling in the early expansion of the developing brain.

Britto J, Tannahill D, Keynes R.

Nat Neurosci. 2002 Feb;5(2):103-10.

PMID:
11788837
31.

Studies of multimodal gating of the sodium channel.

Keynes RD.

Novartis Found Symp. 2002;241:5-14; discussion 14-20, 226-32. Review.

PMID:
11771650
32.

The role of the notochord in vertebral column formation.

Fleming A, Keynes RJ, Tannahill D.

J Anat. 2001 Jul-Aug;199(Pt 1-2):177-80. Review.

33.

Neural crest patterning and the evolution of the jaw.

Kimmel CB, Miller CT, Keynes RJ.

J Anat. 2001 Jul-Aug;199(Pt 1-2):105-20. Review.

34.

Spinal nerve segmentation in the chick embryo: analysis of distinct axon-repulsive systems.

Vermeren MM, Cook GM, Johnson AR, Keynes RJ, Tannahill D.

Dev Biol. 2000 Sep 1;225(1):241-52.

35.

Peripheral, but not central, axotomy induces neuropilin-1 mRNA expression in adult large diameter primary sensory neurons.

Gavazzi I, Stonehouse J, Sandvig A, Reza JN, Appiah-Kubi LS, Keynes R, Cohen J.

J Comp Neurol. 2000 Jul 31;423(3):492-9.

PMID:
10870088
36.

Life, death and Sonic hedgehog.

Britto JM, Tannahill D, Keynes RJ.

Bioessays. 2000 Jun;22(6):499-502. Review.

PMID:
10842302
37.

Orienting axon growth: spinal nerve segmentation and surround-repulsion.

Tannahill D, Britto JM, Vermeren MM, Ohta K, Cook GM, Keynes RJ.

Int J Dev Biol. 2000;44(1):119-27. Review.

38.

European neuroscience meets the snow.

Keynes R, Kirik D, Nieto-Sampedro M.

Trends Neurosci. 2000 Mar;23(3):91-2. No abstract available.

PMID:
10722395
39.

Human oligodendroglial cell line, MO3.13, can be protected from apoptosis using the general caspase inhibitor zVAD-FMK.

Craighead MW, Tiwari P, Keynes RG, Waters CM.

J Neurosci Res. 1999 Jul 15;57(2):236-43.

PMID:
10398301
40.

Embryonic lens repels retinal ganglion cell axons.

Ohta K, Tannahill D, Yoshida K, Johnson AR, Cook GM, Keynes RJ.

Dev Biol. 1999 Jul 1;211(1):124-32.

41.

The screw-helical voltage gating of ion channels.

Keynes RD, Elinder F.

Proc Biol Sci. 1999 Apr 22;266(1421):843-52.

42.

Axon guidance to and from choice points.

Cook G, Tannahill D, Keynes R.

Curr Opin Neurobiol. 1998 Feb;8(1):64-72. Review.

PMID:
9568393
43.
44.

On the slowly rising phase of the sodium gating current in the squid giant axon.

Keynes RD, Elinder F.

Proc Biol Sci. 1998 Feb 22;265(1393):255-62.

45.

Axon guidance and somites

Tannahill D, Cook GMW, Keynes RJ.

Cell Tissue Res. 1998 Feb;291(2):363. No abstract available.

PMID:
9426322
46.

Evanescent science

Keynes R.

Curr Biol. 1998 Jan 1;8(1):R4. No abstract available.

47.

Axon guidance and somites.

Tannahill D, Cook GM, Keynes RJ.

Cell Tissue Res. 1997 Nov;290(2):275-83. Review. Erratum in: Cell Tissue Res 1998 Feb;291(2):363.

PMID:
9321689
48.

Steps on the path to the origin of species.

Keynes RD.

J Theor Biol. 1997 Aug 21;187(4):461-71.

PMID:
9299291
49.

Surround repulsion of spinal sensory axons in higher vertebrate embryos.

Keynes R, Tannahill D, Morgenstern DA, Johnson AR, Cook GM, Pini A.

Neuron. 1997 Jun;18(6):889-97.

50.

Axons turn as netrins find their receptor.

Keynes R, Cook GM.

Neuron. 1996 Dec;17(6):1031-4. Review. No abstract available.

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