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Items: 11

1.

Development and Characterization of Novel and Selective Inhibitors of Cytochrome P450 CYP26A1, the Human Liver Retinoic Acid Hydroxylase.

Diaz P, Huang W, Keyari CM, Buttrick B, Price L, Guilloteau N, Tripathy S, Sperandio VG, Fronczek FR, Astruc-Diaz F, Isoherranen N.

J Med Chem. 2016 Mar 24;59(6):2579-95. doi: 10.1021/acs.jmedchem.5b01780. Epub 2016 Mar 15.

2.

Novel di-aryl-substituted isoxazoles act as noncompetitive inhibitors of the system Xc(-) cystine/glutamate exchanger.

Newell JL, Keyari CM, McDaniel SW, Diaz PJ, Natale NR, Patel SA, Bridges RJ.

Neurochem Int. 2014 Jul;73:132-8. doi: 10.1016/j.neuint.2013.11.012. Epub 2013 Dec 11.

PMID:
24333322
3.

Synthesis of new quinolinequinone derivatives and preliminary exploration of their cytotoxic properties.

Keyari CM, Kearns AK, Duncan NS, Eickholt EA, Abbott G, Beall HD, Diaz P.

J Med Chem. 2013 May 23;56(10):3806-19. doi: 10.1021/jm301689x. Epub 2013 May 1.

4.

Suzuki-Miyaura Cross-Coupling of Benzylic Bromides Under Microwave Conditions.

McDaniel SW, Keyari CM, Rider KC, Natale NR, Diaz P.

Tetrahedron Lett. 2011 Oct 26;52(43):5656-5658.

5.

Asymmetric [C + NC + CC] coupling entry to the naphthyridinomycin natural product family: formal total synthesis of cyanocycline A and bioxalomycin β2.

Garner P, Kaniskan HÜ, Keyari CM, Weerasinghe L.

J Org Chem. 2011 Jul 1;76(13):5283-94. doi: 10.1021/jo200553g. Epub 2011 May 31.

PMID:
21627169
6.

(S)-Methyl 2-{(S)-2-[bis-(4-meth-oxy-phen-yl)methyl-idene-amino]-3-hy-droxy-propanamido}-3-methyl-butano-ate.

Keyari CM, Polt R, Nichol GS.

Acta Crystallogr Sect E Struct Rep Online. 2010 Dec 4;67(Pt 1):o13-4. doi: 10.1107/S1600536810049032.

7.

Glycosyl-enkephalins: synthesis and binding at the mu, delta & kappa opioid receptors. Antinociception in mice.

Keyari CM, Knapp BI, Bidlack JM, Lowey J, Bilsky EJ, Polt R.

Adv Exp Med Biol. 2009;611:495-6. No abstract available.

PMID:
19400281
8.

Glycosylation improves the central effects of DAMGO.

Lowery JJ, Yeomans L, Keyari CM, Davis P, Porreca F, Knapp BI, Bidlack JM, Bilsky EJ, Polt R.

Chem Biol Drug Des. 2007 Jan;69(1):41-7.

PMID:
17313456
9.

Glycosylated neuropeptides: a new vista for neuropsychopharmacology?

Polt R, Dhanasekaran M, Keyari CM.

Med Res Rev. 2005 Sep;25(5):557-85. Review.

PMID:
16075406
10.

Glycopeptides related to beta-endorphin adopt helical amphipathic conformations in the presence of lipid bilayers.

Dhanasekaran M, Palian MM, Alves I, Yeomans L, Keyari CM, Davis P, Bilsky EJ, Egleton RD, Yamamura HI, Jacobsen NE, Tollin G, Hruby VJ, Porreca F, Polt R.

J Am Chem Soc. 2005 Apr 20;127(15):5435-48.

PMID:
15826181
11.

Antinociceptive structure-activity studies with enkephalin-based opioid glycopeptides.

Elmagbari NO, Egleton RD, Palian MM, Lowery JJ, Schmid WR, Davis P, Navratilova E, Dhanasekaran M, Keyari CM, Yamamura HI, Porreca F, Hruby VJ, Polt R, Bilsky EJ.

J Pharmacol Exp Ther. 2004 Oct;311(1):290-7. Epub 2004 May 27.

PMID:
15166257

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