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Items: 1 to 50 of 68

1.

HIV-1 matrix trimerization-impaired mutants are rescued by matrix substitutions that enhance envelope glycoprotein incorporation.

Tedbury PR, Novikova M, Alfadhli A, Hikichi Y, Kagiampakis I, KewalRamani VN, Barklis E, Freed EO.

J Virol. 2019 Oct 16. pii: JVI.01526-19. doi: 10.1128/JVI.01526-19. [Epub ahead of print]

PMID:
31619553
2.

Interferon-Inducible MicroRNA miR-128 Modulates HIV-1 Replication by Targeting TNPO3 mRNA.

Bochnakian A, Zhen A, Zisoulis DG, Idica A, KewalRamani VN, Neel N, Daugaard I, Hamdorf M, Kitchen S, Lee K, Pedersen IM.

J Virol. 2019 Sep 30;93(20). pii: e00364-19. doi: 10.1128/JVI.00364-19. Print 2019 Oct 15.

PMID:
31341054
3.

A single gp120 residue can affect HIV-1 tropism in macaques.

Del Prete GQ, Keele BF, Fode J, Thummar K, Swanstrom AE, Rodriguez A, Raymond A, Estes JD, LaBranche CC, Montefiori DC, KewalRamani VN, Lifson JD, Bieniasz PD, Hatziioannou T.

PLoS Pathog. 2017 Sep 25;13(9):e1006572. doi: 10.1371/journal.ppat.1006572. eCollection 2017 Sep.

4.

Bolaamphiphiles as carriers for siRNA delivery: From chemical syntheses to practical applications.

Gupta K, Afonin KA, Viard M, Herrero V, Kasprzak W, Kagiampakis I, Kim T, Koyfman AY, Puri A, Stepler M, Sappe A, KewalRamani VN, Grinberg S, Linder C, Heldman E, Blumenthal R, Shapiro BA.

J Control Release. 2015 Sep 10;213:142-151. doi: 10.1016/j.jconrel.2015.06.041. Epub 2015 Jul 4.

5.

STRUCTURAL VIROLOGY. X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability.

Gres AT, Kirby KA, KewalRamani VN, Tanner JJ, Pornillos O, Sarafianos SG.

Science. 2015 Jul 3;349(6243):99-103. doi: 10.1126/science.aaa5936. Epub 2015 Jun 4.

6.

Triggering of RNA interference with RNA-RNA, RNA-DNA, and DNA-RNA nanoparticles.

Afonin KA, Viard M, Kagiampakis I, Case CL, Dobrovolskaia MA, Hofmann J, Vrzak A, Kireeva M, Kasprzak WK, KewalRamani VN, Shapiro BA.

ACS Nano. 2015 Jan 27;9(1):251-9. doi: 10.1021/nn504508s. Epub 2014 Dec 18.

7.

Selection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteins.

Del Prete GQ, Ailers B, Moldt B, Keele BF, Estes JD, Rodriguez A, Sampias M, Oswald K, Fast R, Trubey CM, Chertova E, Smedley J, LaBranche CC, Montefiori DC, Burton DR, Shaw GM, Markowitz M, Piatak M Jr, KewalRamani VN, Bieniasz PD, Lifson JD, Hatziioannou T.

Cell Host Microbe. 2014 Sep 10;16(3):412-8. doi: 10.1016/j.chom.2014.08.003.

8.

HIV-1-induced AIDS in monkeys.

Hatziioannou T, Del Prete GQ, Keele BF, Estes JD, McNatt MW, Bitzegeio J, Raymond A, Rodriguez A, Schmidt F, Mac Trubey C, Smedley J, Piatak M Jr, KewalRamani VN, Lifson JD, Bieniasz PD.

Science. 2014 Jun 20;344(6190):1401-5. doi: 10.1126/science.1250761.

9.

Structural basis for nuclear import of splicing factors by human Transportin 3.

Maertens GN, Cook NJ, Wang W, Hare S, Gupta SS, Öztop I, Lee K, Pye VE, Cosnefroy O, Snijders AP, KewalRamani VN, Fassati A, Engelman A, Cherepanov P.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2728-33. doi: 10.1073/pnas.1320755111. Epub 2014 Jan 21.

10.

Co-transcriptional production of RNA-DNA hybrids for simultaneous release of multiple split functionalities.

Afonin KA, Desai R, Viard M, Kireeva ML, Bindewald E, Case CL, Maciag AE, Kasprzak WK, Kim T, Sappe A, Stepler M, Kewalramani VN, Kashlev M, Blumenthal R, Shapiro BA.

Nucleic Acids Res. 2014 Feb;42(3):2085-97. doi: 10.1093/nar/gkt1001. Epub 2013 Nov 4.

11.

Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integration.

Koh Y, Wu X, Ferris AL, Matreyek KA, Smith SJ, Lee K, KewalRamani VN, Hughes SH, Engelman A.

J Virol. 2013 Jan;87(1):648-58. doi: 10.1128/JVI.01148-12. Epub 2012 Oct 24.

12.

CPSF6 defines a conserved capsid interface that modulates HIV-1 replication.

Price AJ, Fletcher AJ, Schaller T, Elliott T, Lee K, KewalRamani VN, Chin JW, Towers GJ, James LC.

PLoS Pathog. 2012;8(8):e1002896. doi: 10.1371/journal.ppat.1002896. Epub 2012 Aug 30.

13.

Ultrasensitive allele-specific PCR reveals rare preexisting drug-resistant variants and a large replicating virus population in macaques infected with a simian immunodeficiency virus containing human immunodeficiency virus reverse transcriptase.

Boltz VF, Ambrose Z, Kearney MF, Shao W, Kewalramani VN, Maldarelli F, Mellors JW, Coffin JM.

J Virol. 2012 Dec;86(23):12525-30. doi: 10.1128/JVI.01963-12. Epub 2012 Aug 29.

14.

Nucleic Acid, Antibody, and Virus Culture Methods to Detect Xenotropic MLV-Related Virus in Human Blood Samples.

Kearney MF, Lee K, Bagni RK, Wiegand A, Spindler J, Maldarelli F, Pinto PA, Linehan WM, Vocke CD, Delviks-Frankenberry KA, Devere White RW, Del Prete GQ, Mellors JW, Lifson JD, Kewalramani VN, Pathak VK, Coffin JM, Le Grice SF.

Adv Virol. 2011;2011:272193. doi: 10.1155/2011/272193. Epub 2011 Nov 17.

15.

Human immunodeficiency virus type 1 capsid mutation N74D alters cyclophilin A dependence and impairs macrophage infection.

Ambrose Z, Lee K, Ndjomou J, Xu H, Oztop I, Matous J, Takemura T, Unutmaz D, Engelman A, Hughes SH, KewalRamani VN.

J Virol. 2012 Apr;86(8):4708-14. doi: 10.1128/JVI.05887-11. Epub 2012 Feb 1.

16.

HIV-1 capsid-targeting domain of cleavage and polyadenylation specificity factor 6.

Lee K, Mulky A, Yuen W, Martin TD, Meyerson NR, Choi L, Yu H, Sawyer SL, Kewalramani VN.

J Virol. 2012 Apr;86(7):3851-60. doi: 10.1128/JVI.06607-11. Epub 2012 Feb 1.

17.

Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques.

Del Prete GQ, Kearney MF, Spindler J, Wiegand A, Chertova E, Roser JD, Estes JD, Hao XP, Trubey CM, Lara A, Lee K, Chaipan C, Bess JW Jr, Nagashima K, Keele BF, Macallister R, Smedley J, Pathak VK, Kewalramani VN, Coffin JM, Lifson JD.

J Virol. 2012 Mar;86(6):3152-66. doi: 10.1128/JVI.06886-11. Epub 2012 Jan 11.

18.

HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency.

Schaller T, Ocwieja KE, Rasaiyaah J, Price AJ, Brady TL, Roth SL, Hué S, Fletcher AJ, Lee K, KewalRamani VN, Noursadeghi M, Jenner RG, James LC, Bushman FD, Towers GJ.

PLoS Pathog. 2011 Dec;7(12):e1002439. doi: 10.1371/journal.ppat.1002439. Epub 2011 Dec 8.

19.

Genetic diversity of simian immunodeficiency virus encoding HIV-1 reverse transcriptase persists in macaques despite antiretroviral therapy.

Kearney M, Spindler J, Shao W, Maldarelli F, Palmer S, Hu SL, Lifson JD, KewalRamani VN, Mellors JW, Coffin JM, Ambrose Z.

J Virol. 2011 Jan;85(2):1067-76. doi: 10.1128/JVI.01701-10. Epub 2010 Nov 17.

20.

Flexible use of nuclear import pathways by HIV-1.

Lee K, Ambrose Z, Martin TD, Oztop I, Mulky A, Julias JG, Vandegraaff N, Baumann JG, Wang R, Yuen W, Takemura T, Shelton K, Taniuchi I, Li Y, Sodroski J, Littman DR, Coffin JM, Hughes SH, Unutmaz D, Engelman A, KewalRamani VN.

Cell Host Microbe. 2010 Mar 18;7(3):221-33. doi: 10.1016/j.chom.2010.02.007.

21.

Perturbation of the P-body component Mov10 inhibits HIV-1 infectivity.

Furtak V, Mulky A, Rawlings SA, Kozhaya L, Lee K, Kewalramani VN, Unutmaz D.

PLoS One. 2010 Feb 5;5(2):e9081. doi: 10.1371/journal.pone.0009081.

22.

RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy.

Shao W, Kearney M, Maldarelli F, Mellors JW, Stephens RM, Lifson JD, KewalRamani VN, Ambrose Z, Coffin JM, Palmer SE.

Retrovirology. 2009 Nov 4;6:101. doi: 10.1186/1742-4690-6-101.

23.

The requirement for cellular transportin 3 (TNPO3 or TRN-SR2) during infection maps to human immunodeficiency virus type 1 capsid and not integrase.

Krishnan L, Matreyek KA, Oztop I, Lee K, Tipper CH, Li X, Dar MJ, Kewalramani VN, Engelman A.

J Virol. 2010 Jan;84(1):397-406. doi: 10.1128/JVI.01899-09. Epub 2009 Oct 21.

24.

HIV-1 transmission by dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN) is regulated by determinants in the carbohydrate recognition domain that are absent in liver/lymph node-SIGN (L-SIGN).

Chung NP, Breun SK, Bashirova A, Baumann JG, Martin TD, Karamchandani JM, Rausch JW, Le Grice SF, Wu L, Carrington M, Kewalramani VN.

J Biol Chem. 2010 Jan 15;285(3):2100-12. doi: 10.1074/jbc.M109.030619. Epub 2009 Oct 15.

25.

A macaque model of HIV-1 infection.

Hatziioannou T, Ambrose Z, Chung NP, Piatak M Jr, Yuan F, Trubey CM, Coalter V, Kiser R, Schneider D, Smedley J, Pung R, Gathuka M, Estes JD, Veazey RS, KewalRamani VN, Lifson JD, Bieniasz PD.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4425-9. doi: 10.1073/pnas.0812587106. Epub 2009 Mar 2.

26.

Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo.

Michel N, Goffinet C, Ganter K, Allespach I, Kewalramani VN, Saifuddin M, Littman DR, Greene WC, Goldsmith MA, Keppler OT.

Retrovirology. 2009 Jan 13;6:2. doi: 10.1186/1742-4690-6-2.

27.

Incomplete protection against simian immunodeficiency virus vaginal transmission in rhesus macaques by a topical antiviral agent revealed by repeat challenges.

Ambrose Z, Compton L, Piatak M Jr, Lu D, Alvord WG, Lubomirski MS, Hildreth JE, Lifson JD, Miller CJ, KewalRamani VN.

J Virol. 2008 Jul;82(13):6591-9. doi: 10.1128/JVI.02730-07. Epub 2008 Apr 23.

28.

The LEM domain proteins emerin and LAP2alpha are dispensable for human immunodeficiency virus type 1 and murine leukemia virus infections.

Mulky A, Cohen TV, Kozlov SV, Korbei B, Foisner R, Stewart CL, KewalRamani VN.

J Virol. 2008 Jun;82(12):5860-8. doi: 10.1128/JVI.00076-08. Epub 2008 Apr 9.

29.

Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy.

Ambrose Z, Palmer S, Boltz VF, Kearney M, Larsen K, Polacino P, Flanary L, Oswald K, Piatak M Jr, Smedley J, Shao W, Bischofberger N, Maldarelli F, Kimata JT, Mellors JW, Hu SL, Coffin JM, Lifson JD, KewalRamani VN.

J Virol. 2007 Nov;81(22):12145-55. Epub 2007 Sep 12.

30.

HIV/AIDS: in search of an animal model.

Ambrose Z, KewalRamani VN, Bieniasz PD, Hatziioannou T.

Trends Biotechnol. 2007 Aug;25(8):333-7. Epub 2007 Jun 18. Review.

PMID:
17574286
31.

CD4 coexpression regulates DC-SIGN-mediated transmission of human immunodeficiency virus type 1.

Wang JH, Janas AM, Olson WJ, KewalRamani VN, Wu L.

J Virol. 2007 Mar;81(5):2497-507. Epub 2006 Dec 6.

32.

Dendritic-cell interactions with HIV: infection and viral dissemination.

Wu L, KewalRamani VN.

Nat Rev Immunol. 2006 Nov;6(11):859-68. Review.

35.

Role of DC-SIGN in the activation of dendritic cells by HPV-16 L1 virus-like particle vaccine.

García-Piñeres AJ, Hildesheim A, Trivett M, Williams M, Wu L, Kewalramani VN, Pinto LA.

Eur J Immunol. 2006 Feb;36(2):437-45.

36.

Antimicrobial peptides from amphibian skin potently inhibit human immunodeficiency virus infection and transfer of virus from dendritic cells to T cells.

VanCompernolle SE, Taylor RJ, Oswald-Richter K, Jiang J, Youree BE, Bowie JH, Tyler MJ, Conlon JM, Wade D, Aiken C, Dermody TS, KewalRamani VN, Rollins-Smith LA, Unutmaz D.

J Virol. 2005 Sep;79(18):11598-606.

38.

Murine T cells potently restrict human immunodeficiency virus infection.

Baumann JG, Unutmaz D, Miller MD, Breun SK, Grill SM, Mirro J, Littman DR, Rein A, KewalRamani VN.

J Virol. 2004 Nov;78(22):12537-47.

39.

In defense of the cell: TRIM5alpha interception of mammalian retroviruses.

Lee K, KewalRamani VN.

Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10496-7. Epub 2004 Jul 13. No abstract available.

40.

Trans-dominant cellular inhibition of DC-SIGN-mediated HIV-1 transmission.

Wu L, Martin TD, Han YC, Breun SK, KewalRamani VN.

Retrovirology. 2004 Jun 28;1:14.

41.

Elevated expression of GM3 in receptor-bearing targets confers resistance to human immunodeficiency virus type 1 fusion.

Rawat SS, Gallo SA, Eaton J, Martin TD, Ablan S, KewalRamani VN, Wang JM, Blumenthal R, Puri A.

J Virol. 2004 Jul;78(14):7360-8.

42.

Functional expression of CD4, CXCR4, and CCR5 in glycosphingolipid-deficient mouse melanoma GM95 cells and susceptibility to HIV-1 envelope glycoprotein-triggered membrane fusion.

Rawat SS, Eaton J, Gallo SA, Martin TD, Ablan S, Ratnayake S, Viard M, KewalRamani VN, Wang JM, Blumenthal R, Puri A.

Virology. 2004 Jan 5;318(1):55-65.

43.

Raji B cells, misidentified as THP-1 cells, stimulate DC-SIGN-mediated HIV transmission.

Wu L, Martin TD, Carrington M, KewalRamani VN.

Virology. 2004 Jan 5;318(1):17-23.

44.

Nonrandom HIV-1 infection and double infection via direct and cell-mediated pathways.

Dang Q, Chen J, Unutmaz D, Coffin JM, Pathak VK, Powell D, KewalRamani VN, Maldarelli F, Hu WS.

Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):632-7. Epub 2004 Jan 5.

45.

Virology. Weapons of mutational destruction.

KewalRamani VN, Coffin JM.

Science. 2003 Aug 15;301(5635):923-5. No abstract available.

PMID:
12920286
46.

Recruitment of HIV and its receptors to dendritic cell-T cell junctions.

McDonald D, Wu L, Bohks SM, KewalRamani VN, Unutmaz D, Hope TJ.

Science. 2003 May 23;300(5623):1295-7. Epub 2003 May 1.

47.

Novel member of the CD209 (DC-SIGN) gene family in primates.

Bashirova AA, Wu L, Cheng J, Martin TD, Martin MP, Benveniste RE, Lifson JD, KewalRamani VN, Hughes A, Carrington M.

J Virol. 2003 Jan;77(1):217-27.

50.

Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN.

Wu L, Bashirova AA, Martin TD, Villamide L, Mehlhop E, Chertov AO, Unutmaz D, Pope M, Carrington M, KewalRamani VN.

Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1568-73. Epub 2002 Jan 29.

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