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Items: 1 to 50 of 106

1.

Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort.

Westwood S, Baird AL, Anand SN, Nevado-Holgado AJ, Kormilitzin A, Shi L, Hye A, Ashton NJ, Morgan AR, Bos I, Vos SJB, Baker S, Buckley NJ, Ten Kate M, Scheltens P, Teunissen CE, Vandenberghe R, Gabel S, Meersmans K, Engelborghs S, De Roeck EE, Sleegers K, Frisoni GB, Blin O, Richardson JC, Bordet R, Molinuevo JL, Rami L, Wallin A, Kettunen P, Tsolaki M, Verhey F, Lléo A, Sala I, Popp J, Peyratout G, Martinez-Lage P, Tainta M, Johannsen P, Freund-Levi Y, Frölich L, Dobricic V, Legido-Quigley C, Bertram L, Barkhof F, Zetterberg H, Morgan BP, Streffer J, Visser PJ, Lovestone S.

J Alzheimers Dis. 2020 Jan 22. doi: 10.3233/JAD-190434. [Epub ahead of print]

PMID:
31985466
2.

A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort.

Stamate D, Kim M, Proitsi P, Westwood S, Baird A, Nevado-Holgado A, Hye A, Bos I, Vos SJB, Vandenberghe R, Teunissen CE, Kate MT, Scheltens P, Gabel S, Meersmans K, Blin O, Richardson J, De Roeck E, Engelborghs S, Sleegers K, Bordet R, Ramit L, Kettunen P, Tsolaki M, Verhey F, Alcolea D, Lléo A, Peyratout G, Tainta M, Johannsen P, Freund-Levi Y, Frölich L, Dobricic V, Frisoni GB, Molinuevo JL, Wallin A, Popp J, Martinez-Lage P, Bertram L, Blennow K, Zetterberg H, Streffer J, Visser PJ, Lovestone S, Legido-Quigley C.

Alzheimers Dement (N Y). 2019 Dec 18;5:933-938. doi: 10.1016/j.trci.2019.11.001. eCollection 2019.

3.

Latent Cognitive Profiles Differ Between Incipient Alzheimer's Disease and Dementia with Subcortical Vascular Lesions in a Memory Clinic Population.

Göthlin M, Eckerström M, Lindwall M, Rolstad S, Eckerström C, Jonsson M, Kettunen P, Svensson J, Wallin A.

J Alzheimers Dis. 2020;73(3):955-966. doi: 10.3233/JAD-190515.

PMID:
31868665
4.

Characteristic Biomarker and Cognitive Profile in Incipient Mixed Dementia.

Eckerström C, Eckerström M, Göthlin M, Molinder A, Jonsson M, Kettunen P, Svensson J, Rolstad S, Wallin A.

J Alzheimers Dis. 2020;73(2):597-607. doi: 10.3233/JAD-190651.

PMID:
31815692
5.

Calcium Imaging in the Zebrafish.

Kettunen P.

Adv Exp Med Biol. 2020;1131:901-942. doi: 10.1007/978-3-030-12457-1_36. Review.

PMID:
31646539
6.

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay.

Shi L, Westwood S, Baird AL, Winchester L, Dobricic V, Kilpert F, Hong S, Franke A, Hye A, Ashton NJ, Morgan AR, Bos I, Vos SJB, Buckley NJ, Kate MT, Scheltens P, Vandenberghe R, Gabel S, Meersmans K, Engelborghs S, De Roeck EE, Sleegers K, Frisoni GB, Blin O, Richardson JC, Bordet R, Molinuevo JL, Rami L, Wallin A, Kettunen P, Tsolaki M, Verhey F, Lleó A, Alcolea D, Popp J, Peyratout G, Martinez-Lage P, Tainta M, Johannsen P, Teunissen CE, Freund-Levi Y, Frölich L, Legido-Quigley C, Barkhof F, Blennow K, Zetterberg H, Baker S, Morgan BP, Streffer J, Visser PJ, Bertram L, Lovestone S, Nevado-Holgado AJ.

Alzheimers Dement. 2019 Nov;15(11):1478-1488. doi: 10.1016/j.jalz.2019.06.4951. Epub 2019 Sep 5.

7.

Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort.

Kim M, Snowden S, Suvitaival T, Ali A, Merkler DJ, Ahmad T, Westwood S, Baird A, Proitsi P, Nevado-Holgado A, Hye A, Bos I, Vos S, Vandenberghe R, Teunissen C, Ten Kate M, Scheltens P, Gabel S, Meersmans K, Blin O, Richardson J, De Roeck E, Sleegers K, Bordet R, Rami L, Kettunen P, Tsolaki M, Verhey F, Sala I, Lléo A, Peyratout G, Tainta M, Johannsen P, Freund-Levi Y, Frölich L, Dobricic V, Engelborghs S, Frisoni GB, Molinuevo JL, Wallin A, Popp J, Martinez-Lage P, Bertram L, Barkhof F, Ashton N, Blennow K, Zetterberg H, Streffer J, Visser PJ, Lovestone S, Legido-Quigley C.

Alzheimers Dement. 2019 Jun;15(6):817-827. doi: 10.1016/j.jalz.2019.03.004. Epub 2019 May 8.

8.

Inflammatory biomarkers in Alzheimer's disease plasma.

Morgan AR, Touchard S, Leckey C, O'Hagan C, Nevado-Holgado AJ; NIMA Consortium, Barkhof F, Bertram L, Blin O, Bos I, Dobricic V, Engelborghs S, Frisoni G, Frölich L, Gabel S, Johannsen P, Kettunen P, Kłoszewska I, Legido-Quigley C, Lleó A, Martinez-Lage P, Mecocci P, Meersmans K, Molinuevo JL, Peyratout G, Popp J, Richardson J, Sala I, Scheltens P, Streffer J, Soininen H, Tainta-Cuezva M, Teunissen C, Tsolaki M, Vandenberghe R, Visser PJ, Vos S, Wahlund LO, Wallin A, Westwood S, Zetterberg H, Lovestone S, Morgan BP; Annex: NIMA–Wellcome Trust Consortium for Neuroimmunology of Mood Disorders and Alzheimer's Disease.

Alzheimers Dement. 2019 Jun;15(6):776-787. doi: 10.1016/j.jalz.2019.03.007. Epub 2019 Apr 30.

9.

Establishment of tooth blood supply and innervation is developmentally regulated and takes place through differential patterning processes.

Shadad O, Chaulagain R, Luukko K, Kettunen P.

J Anat. 2019 Apr;234(4):465-479. doi: 10.1111/joa.12950. Epub 2019 Feb 21.

PMID:
30793310
10.

Better prognostic accuracy in younger mild cognitive impairment patients with more years of education.

Göthlin M, Eckerström M, Rolstad S, Kettunen P, Wallin A.

Alzheimers Dement (Amst). 2018 Jun 8;10:402-412. doi: 10.1016/j.dadm.2018.05.001. eCollection 2018.

11.

Amyloid-β, Tau, and Cognition in Cognitively Normal Older Individuals: Examining the Necessity to Adjust for Biomarker Status in Normative Data.

Bos I, Vos SJB, Jansen WJ, Vandenberghe R, Gabel S, Estanga A, Ecay-Torres M, Tomassen J, den Braber A, Lleó A, Sala I, Wallin A, Kettunen P, Molinuevo JL, Rami L, Chetelat G, de la Sayette V, Tsolaki M, Freund-Levi Y, Johannsen P; Alzheimer's Disease Neuroimaging Initiative, Novak GP, Ramakers I, Verhey FR, Visser PJ.

Front Aging Neurosci. 2018 Jun 25;10:193. doi: 10.3389/fnagi.2018.00193. eCollection 2018.

12.

Update on Vascular Cognitive Impairment Associated with Subcortical Small-Vessel Disease.

Wallin A, Román GC, Esiri M, Kettunen P, Svensson J, Paraskevas GP, Kapaki E.

J Alzheimers Dis. 2018;62(3):1417-1441. doi: 10.3233/JAD-170803. Review.

13.

Cognitive medicine - a new approach in health care science.

Wallin A, Kettunen P, Johansson PM, Jonsdottir IH, Nilsson C, Nilsson M, Eckerström M, Nordlund A, Nyberg L, Sunnerhagen KS, Svensson J, Terzis B, Wahlund LO, Georg Kuhn H.

BMC Psychiatry. 2018 Feb 8;18(1):42. doi: 10.1186/s12888-018-1615-0.

14.

Low-dose γ-secretase inhibition increases secretion of Aβ peptides and intracellular oligomeric Aβ.

Agholme L, Clarin M, Gkanatsiou E, Kettunen P, Chebli J, Brinkmalm G, Blennow K, Bergström P, Portelius E, Zetterberg H.

Mol Cell Neurosci. 2017 Dec;85:211-219. doi: 10.1016/j.mcn.2017.10.009. Epub 2017 Nov 8.

PMID:
29104140
15.

QKI6B mRNA levels are upregulated in schizophrenia and predict GFAP expression.

Farnsworth B, Radomska KJ, Zimmermann B, Kettunen P, Jazin E, Emilsson LS.

Brain Res. 2017 Aug 15;1669:63-68. doi: 10.1016/j.brainres.2017.05.027. Epub 2017 May 25.

PMID:
28552414
16.

Psychosocial risk factors and treatment of new onset and recurrent depression during the post-partum period.

Kettunen P, Hintikka J.

Nord J Psychiatry. 2017 Jul;71(5):355-361. doi: 10.1080/08039488.2017.1300324. Epub 2017 Mar 14.

PMID:
28290763
17.

Stem cell cultures derived from pediatric brain tumors accurately model the originating tumors.

Wenger A, Larsson S, Danielsson A, Elbæk KJ, Kettunen P, Tisell M, Sabel M, Lannering B, Nordborg C, Schepke E, Carén H.

Oncotarget. 2017 Mar 21;8(12):18626-18639. doi: 10.18632/oncotarget.14826.

18.

Proteomic analyses of limbic regions in neonatal male, female and androgen receptor knockout mice.

Zettergren A, Karlsson S, Studer E, Sarvimäki A, Kettunen P, Thorsell A, Sihlbom C, Westberg L.

BMC Neurosci. 2017 Jan 5;18(1):9. doi: 10.1186/s12868-016-0332-1.

20.
21.

A Genetic Variant of the Sortilin 1 Gene is Associated with Reduced Risk of Alzheimer's Disease.

Andersson CH, Hansson O, Minthon L, Andreasen N, Blennow K, Zetterberg H, Skoog I, Wallin A, Nilsson S, Kettunen P.

J Alzheimers Dis. 2016 Jul 1;53(4):1353-63. doi: 10.3233/JAD-160319.

22.

Gene Expression of Quaking in Sporadic Alzheimer's Disease Patients is Both Upregulated and Related to Expression Levels of Genes Involved in Amyloid Plaque and Neurofibrillary Tangle Formation.

Farnsworth B, Peuckert C, Zimmermann B, Jazin E, Kettunen P, Emilsson LS.

J Alzheimers Dis. 2016 May 6;53(1):209-19. doi: 10.3233/JAD-160160.

23.

Neural Androgen Receptors Modulate Gene Expression and Social Recognition But Not Social Investigation.

Karlsson SA, Studer E, Kettunen P, Westberg L.

Front Behav Neurosci. 2016 Mar 16;10:41. doi: 10.3389/fnbeh.2016.00041. eCollection 2016.

24.

β-Amyloid precursor protein-b is essential for Mauthner cell development in the zebrafish in a Notch-dependent manner.

Banote RK, Edling M, Eliassen F, Kettunen P, Zetterberg H, Abramsson A.

Dev Biol. 2016 May 1;413(1):26-38. doi: 10.1016/j.ydbio.2016.03.012. Epub 2016 Mar 16.

25.

Characterization and Expression of the Zebrafish qki Paralogs.

Radomska KJ, Sager J, Farnsworth B, Tellgren-Roth Å, Tuveri G, Peuckert C, Kettunen P, Jazin E, Emilsson LS.

PLoS One. 2016 Jan 4;11(1):e0146155. doi: 10.1371/journal.pone.0146155. eCollection 2016.

26.

Effects of sex and gonadectomy on social investigation and social recognition in mice.

Karlsson SA, Haziri K, Hansson E, Kettunen P, Westberg L.

BMC Neurosci. 2015 Nov 25;16:83. doi: 10.1186/s12868-015-0221-z.

27.

A Caged Ret Kinase Inhibitor and its Effect on Motoneuron Development in Zebrafish Embryos.

Bliman D, Nilsson JR, Kettunen P, Andréasson J, Grøtli M.

Sci Rep. 2015 Aug 24;5:13109. doi: 10.1038/srep13109.

28.

Is postpartum depression a homogenous disorder: time of onset, severity, symptoms and hopelessness in relation to the course of depression.

Kettunen P, Koistinen E, Hintikka J.

BMC Pregnancy Childbirth. 2014 Dec 10;14:402. doi: 10.1186/s12884-014-0402-2.

29.

Genetic variants of GSK3B are associated with biomarkers for Alzheimer's disease and cognitive function.

Kettunen P, Larsson S, Holmgren S, Olsson S, Minthon L, Zetterberg H, Blennow K, Nilsson S, Sjölander A.

J Alzheimers Dis. 2015;44(4):1313-22. doi: 10.3233/JAD-142025.

PMID:
25420549
30.

Sema3A chemorepellant regulates the timing and patterning of dental nerves during development of incisor tooth germ.

Shrestha A, Moe K, Luukko K, Taniguchi M, Kettunen P.

Cell Tissue Res. 2014 Jul;357(1):15-29. doi: 10.1007/s00441-014-1839-3. Epub 2014 Apr 22.

PMID:
24752460
31.

Coordination of tooth morphogenesis and neuronal development through tissue interactions: lessons from mouse models.

Luukko K, Kettunen P.

Exp Cell Res. 2014 Jul 15;325(2):72-7. doi: 10.1016/j.yexcr.2014.02.029. Epub 2014 Mar 11. Review.

PMID:
24631295
32.

The zebrafish amyloid precursor protein-b is required for motor neuron guidance and synapse formation.

Abramsson A, Kettunen P, Banote RK, Lott E, Li M, Arner A, Zetterberg H.

Dev Biol. 2013 Sep 15;381(2):377-88. doi: 10.1016/j.ydbio.2013.06.026. Epub 2013 Jul 9.

33.

Landmarks in nature to support wayfinding: the effects of seasons and experimental methods.

Kettunen P, Irvankoski K, Krause CM, Sarjakoski LT.

Cogn Process. 2013 Aug;14(3):245-53. doi: 10.1007/s10339-013-0538-4. Epub 2013 Feb 8.

PMID:
23392783
34.

Semaphorin 3A controls timing and patterning of the dental pulp innervation.

Moe K, Sijaona A, Shrestha A, Kettunen P, Taniguchi M, Luukko K.

Differentiation. 2012 Dec;84(5):371-9. doi: 10.1016/j.diff.2012.09.003. Epub 2012 Nov 7.

PMID:
23142733
35.

A novel ARC gene polymorphism is associated with reduced risk of Alzheimer's disease.

Landgren S, von Otter M, Palmér MS, Zetterström C, Nilsson S, Skoog I, Gustafson DR, Minthon L, Wallin A, Andreasen N, Bogdanovic N, Marcusson J, Blennow K, Zetterberg H, Kettunen P.

J Neural Transm (Vienna). 2012 Jul;119(7):833-42. doi: 10.1007/s00702-012-0823-x. Epub 2012 May 25.

PMID:
22622366
36.

Calcium imaging in the zebrafish.

Kettunen P.

Adv Exp Med Biol. 2012;740:1039-71. doi: 10.1007/978-94-007-2888-2_48. Review.

PMID:
22453983
37.

Expression patterns of Sema3F, PlexinA4, -A3, Neuropilin1 and -2 in the postnatal mouse molar suggest roles in tooth innervation and organogenesis.

Sijaona A, Luukko K, Kvinnsland IH, Kettunen P.

Acta Odontol Scand. 2012 Mar;70(2):140-8. doi: 10.3109/00016357.2011.600708. Epub 2011 Aug 5.

PMID:
21815834
38.

Developmentally regulated expression of Sema3A chemorepellant in the developing mouse incisor.

Moe K, Shrestha A, Kvinnsland IH, Luukko K, Kettunen P.

Acta Odontol Scand. 2012 May;70(3):184-9. doi: 10.3109/00016357.2011.600717. Epub 2011 Jul 27.

PMID:
21793640
39.

Developmentally regulated expression of intracellular Fgf11-13, hormone-like Fgf15 and canonical Fgf16, -17 and -20 mRNAs in the developing mouse molar tooth.

Kettunen P, Furmanek T, Chaulagain R, Kvinnsland IH, Luukko K.

Acta Odontol Scand. 2011 Nov;69(6):360-6. doi: 10.3109/00016357.2011.568968. Epub 2011 Mar 30.

PMID:
21449687
40.

Neural circuit activity in freely behaving zebrafish (Danio rerio).

Issa FA, O'Brien G, Kettunen P, Sagasti A, Glanzman DL, Papazian DM.

J Exp Biol. 2011 Mar 15;214(Pt 6):1028-38. doi: 10.1242/jeb.048876.

41.

RNA deep sequencing of the Atlantic cod transcriptome.

Johansen SD, Karlsen BO, Furmanek T, Andreassen M, Jørgensen TE, Bizuayehu TT, Breines R, Emblem A, Kettunen P, Luukko K, Edvardsen RB, Nordeide JT, Coucheron DH, Moum T.

Comp Biochem Physiol Part D Genomics Proteomics. 2011 Mar;6(1):18-22. doi: 10.1016/j.cbd.2010.04.005. Epub 2010 May 20.

PMID:
20493789
42.

Proteomics profiling of single organs from individual adult zebrafish.

Abramsson A, Westman-Brinkmalm A, Pannee J, Gustavsson M, von Otter M, Blennow K, Brinkmalm G, Kettunen P, Zetterberg H.

Zebrafish. 2010 Jun;7(2):161-8. doi: 10.1089/zeb.2009.0644.

PMID:
20392139
43.

Dact1-3 mRNAs exhibit distinct expression domains during tooth development.

Kettunen P, Kivimäe S, Keshari P, Klein OD, Cheyette BN, Luukko K.

Gene Expr Patterns. 2010 Feb-Mar;10(2-3):140-3. doi: 10.1016/j.gep.2010.02.002. Epub 2010 Feb 17.

44.

Separate signalling mechanisms underlie mGluR1 modulation of leak channels and NMDA receptors in the network underlying locomotion.

Nanou E, Kyriakatos A, Kettunen P, El Manira A.

J Physiol. 2009 Jun 15;587(Pt 12):3001-8. doi: 10.1113/jphysiol.2009.172452. Epub 2009 Apr 29.

45.

Development of the pioneer sympathetic innervation into the dental pulp of the mouse mandibular first molar.

Moe K, Kettunen P, Kvinnsland IH, Luukko K.

Arch Oral Biol. 2008 Sep;53(9):865-73. doi: 10.1016/j.archoralbio.2008.03.004. Epub 2008 Apr 23.

PMID:
18436190
46.

Secondary induction and the development of tooth nerve supply.

Luukko K, Moe K, Sijaona A, Furmanek T, Hals Kvinnsland I, Midtbø M, Kettunen P.

Ann Anat. 2008;190(2):178-87. doi: 10.1016/j.aanat.2007.10.003. Epub 2008 Feb 21. Review.

PMID:
18413271
47.

Measurement of EMG activity with textile electrodes embedded into clothing.

Finni T, Hu M, Kettunen P, Vilavuo T, Cheng S.

Physiol Meas. 2007 Nov;28(11):1405-19. Epub 2007 Oct 12.

PMID:
17978424
48.

Fgfr2b mediated epithelial-mesenchymal interactions coordinate tooth morphogenesis and dental trigeminal axon patterning.

Kettunen P, Spencer-Dene B, Furmanek T, Kvinnsland IH, Dickson C, Thesleff I, Luukko K.

Mech Dev. 2007 Nov-Dec;124(11-12):868-83. Epub 2007 Sep 19.

49.

The Nordic welfare state in Finland.

Kettunen P.

Scand J Hist. 2001;26(3):225-47. No abstract available.

PMID:
17844642
50.

Histological development and dynamic expression of Bmp2-6 mRNAs in the embryonic and postnatal mouse cranial base.

Kettunen P, Nie X, Kvinnsland IH, Luukko K.

Anat Rec A Discov Mol Cell Evol Biol. 2006 Dec;288(12):1250-8.

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