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Items: 1 to 50 of 193

1.

Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease.

Jia Q, Han Y, Huang P, Woodward NC, Gukasyan J, Kettunen J, Ala-Korpela M, Anufrieva O, Wang Q, Perola M, Raitakari O, Lehtimäki T, Viikari J, Järvelin MR, Boehnke M, Laakso M, Mohlke KL, Fiehn O, Wang Z, Tang WHW, Hazen SL, Hartiala JA, Allayee H.

J Am Heart Assoc. 2019 May 21;8(10):e011922. doi: 10.1161/JAHA.119.011922.

2.

A practical approach to improve the statistical performance of surface water monitoring networks.

Kotamäki N, Järvinen M, Kauppila P, Korpinen S, Lensu A, Malve O, Mitikka S, Silander J, Kettunen J.

Environ Monit Assess. 2019 May 1;191(6):318. doi: 10.1007/s10661-019-7475-3.

3.

Direct Estimation of HDL-Mediated Cholesterol Efflux Capacity From Serum.

Kuusisto S, Holmes MV, Ohukainen P, Kangas AJ, Karsikas M, Tiainen M, Perola M, Salomaa V, Kettunen J, Ala-Korpela M.

Clin Chem. 2019 Apr 17. pii: clinchem.2018.299222. doi: 10.1373/clinchem.2018.299222. [Epub ahead of print]

PMID:
30996052
4.

Survival of 11,390 Continuum cups in primary total hip arthroplasty based on data from the Finnish Arthroplasty Register.

Hemmilä M, Karvonen M, Laaksonen I, Matilainen M, Eskelinen A, Haapakoski J, Puhto AP, Kettunen J, Manninen M, Mäkelä KT.

Acta Orthop. 2019 Apr 17:1-10. doi: 10.1080/17453674.2019.1603596. [Epub ahead of print]

PMID:
30994043
5.

Short-term survival of cementless Oxford unicondylar knee arthroplasty based on the Finnish Arthroplasty Register.

Knifsund J, Reito A, Haapakoski J, Niinimäki T, Eskelinen A, Leskinen J, Puhto AP, Kettunen J, Manninen M, Mäkelä KT.

Knee. 2019 Jun;26(3):768-773. doi: 10.1016/j.knee.2019.03.004. Epub 2019 Mar 28.

PMID:
30929792
6.

Genome-wide meta-analysis identifies genetic locus on chromosome 9 associated with Modic changes.

Freidin M, Kraatari M, Skarp S, Määttä J, Kettunen J, Niinimäki J, Karppinen J, Williams F, Männikkö M.

J Med Genet. 2019 Feb 26. pii: jmedgenet-2018-105726. doi: 10.1136/jmedgenet-2018-105726. [Epub ahead of print]

PMID:
30808802
7.

Coronary artery disease, genetic risk and the metabolome in young individuals.

Battram T, Hoskins L, Hughes DA, Kettunen J, Ring SM, Smith GD, Timpson NJ.

Version 2. Wellcome Open Res. 2019 Feb 1 [revised 2019 Jan 1];3:114. doi: 10.12688/wellcomeopenres.14788.2. eCollection 2018.

8.

Age at adiposity rebound in childhood is associated with PCOS diagnosis and obesity in adulthood-longitudinal analysis of BMI data from birth to age 46 in cases of PCOS.

Koivuaho E, Laru J, Ojaniemi M, Puukka K, Kettunen J, Tapanainen JS, Franks S, Järvelin MR, Morin-Papunen L, Sebert S, Piltonen TT.

Int J Obes (Lond). 2019 Feb 4. doi: 10.1038/s41366-019-0318-z. [Epub ahead of print]

9.

Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics.

Tynkkynen T, Wang Q, Ekholm J, Anufrieva O, Ohukainen P, Vepsäläinen J, Männikkö M, Keinänen-Kiukaanniemi S, Holmes MV, Goodwin M, Ring S, Chambers JC, Kooner J, Järvelin MR, Kettunen J, Hill M, Davey Smith G, Ala-Korpela M.

Int J Epidemiol. 2019 Jan 25. doi: 10.1093/ije/dyy287. [Epub ahead of print]

10.

Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances.

Timmers PR, Mounier N, Lall K, Fischer K, Ning Z, Feng X, Bretherick AD, Clark DW; eQTLGen Consortium, Agbessi M, Ahsan H, Alves I, Andiappan A, Awadalla P, Battle A, Bonder MJ, Boomsma D, Christiansen M, Claringbould A, Deelen P, van Dongen J, Esko T, Favé M, Franke L, Frayling T, Gharib SA, Gibson G, Hemani G, Jansen R, Kalnapenkis A, Kasela S, Kettunen J, Kim Y, Kirsten H, Kovacs P, Krohn K, Kronberg-Guzman J, Kukushkina V, Kutalik Z, Kähönen M, Lee B, Lehtimäki T, Loeffler M, Marigorta U, Metspalu A, van Meurs J, Milani L, Müller-Nurasyid M, Nauck M, Nivard M, Penninx B, Perola M, Pervjakova N, Pierce B, Powell J, Prokisch H, Psaty BM, Raitakari O, Ring S, Ripatti S, Rotzschke O, Ruëger S, Saha A, Scholz M, Schramm K, Seppälä I, Stumvoll M, Sullivan P, Teumer A, Thiery J, Tong L, Tönjes A, Verlouw J, Visscher PM, Võsa U, Völker U, Yaghootkar H, Yang J, Zeng B, Zhang F, Agbessi M, Ahsan H, Alves I, Andiappan A, Awadalla P, Battle A, Bonder MJ, Boomsma D, Christiansen M, Claringbould A, Deelen P, van Dongen J, Esko T, Favé M, Franke L, Frayling T, Gharib SA, Gibson G, Hemani G, Jansen R, Kalnapenkis A, Kasela S, Kettunen J, Kim Y, Kirsten H, Kovacs P, Krohn K, Kronberg-Guzman J, Kukushkina V, Kutalik Z, Kähönen M, Lee B, Lehtimäki T, Loeffler M, Marigorta U, Metspalu A, van Meurs J, Milani L, Müller-Nurasyid M, Nauck M, Nivard M, Penninx B, Perola M, Pervjakova N, Pierce B, Powell J, Prokisch H, Psaty BM, Raitakari O, Ring S, Ripatti S, Rotzschke O, Ruëger S, Saha A, Scholz M, Schramm K, Seppälä I, Stumvoll M, Sullivan P, Teumer A, Thiery J, Tong L, Tönjes A, Verlouw J, Visscher PM, Võsa U, Völker U, Yaghootkar H, Yang J, Zeng B, Zhang F, Shen X, Esko T, Kutalik Z, Wilson JF, Joshi PK.

Elife. 2019 Jan 15;8. pii: e39856. doi: 10.7554/eLife.39856.

11.

Biomarker Glycoprotein Acetyls Is Associated With the Risk of a Wide Spectrum of Incident Diseases and Stratifies Mortality Risk in Angiography Patients.

Kettunen J, Ritchie SC, Anufrieva O, Lyytikäinen LP, Hernesniemi J, Karhunen PJ, Kuukasjärvi P, Laurikka J, Kähönen M, Lehtimäki T, Havulinna AS, Salomaa V, Männistö S, Ala-Korpela M, Perola M, Inouye M, Würtz P.

Circ Genom Precis Med. 2018 Nov;11(11):e002234. doi: 10.1161/CIRCGEN.118.002234.

PMID:
30571186
12.

Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment.

Sliz E, Kettunen J, Holmes MV, Williams CO, Boachie C, Wang Q, Männikkö M, Sebert S, Walters R, Lin K, Millwood IY, Clarke R, Li L, Rankin N, Welsh P, Delles C, Jukema JW, Trompet S, Ford I, Perola M, Salomaa V, Järvelin MR, Chen Z, Lawlor DA, Ala-Korpela M, Danesh J, Davey Smith G, Sattar N, Butterworth A, Würtz P.

Circulation. 2018 Nov 27;138(22):2499-2512. doi: 10.1161/CIRCULATIONAHA.118.034942. Epub 2018 Aug 15.

PMID:
30524137
13.

Relationship between retinal vessel diameter with both retinal nerve fibre layer thickness and optic nerve head parameters in middle-aged Caucasians: the Northern Finland Birth Cohort Eye study.

Geneid M, Kettunen J, Nuuttila I, Lintonen T, Uusitalo JJ, Saarela V, Liinamaa MJ.

Acta Ophthalmol. 2018 Dec 10. doi: 10.1111/aos.13992. [Epub ahead of print]

PMID:
30537339
14.

Metabolomic Consequences of Genetic Inhibition of PCSK9 Compared With Statin Treatment

Sliz E, Kettunen J, Holmes MV, Williams CO, Boachie C, Wang Q, Männikkö M, Sebert S, Walters R, Lin K, Millwood LY, Clarke R, Li L, Rankin N, Welsh P, Delles C, Jukema JW, Trompet S, Ford I, Perola M, Salomaa V, Järvelin MR, Chen Z, Lawlor DA, Ala-Korpela M, Danesh J, Smith GD, Sattar N, Butterworth A, Würtz P.

Circulation. 2018 Nov 27;138(22):2499–2512.

15.

Associations of increased physical performance and change in body composition with molecular pathways of heart disease and diabetes risk.

Kettunen J, Joensuu A, Hagnäs M, Mikkola I, Wennerström A, Lee JH, Terwilliger JD, Borodulin K, Jousilahti P, Jauhiainen M, Jokelainen JJ, Keinänen-Kiukaanniemi S, Perola M.

Am J Physiol Endocrinol Metab. 2019 Feb 1;316(2):E221-E229. doi: 10.1152/ajpendo.00260.2018. Epub 2018 Nov 13.

PMID:
30422703
16.

Dislocation of large-diameter head metal-on-metal total hip arthroplasty and hip resurfacing arthroplasty.

Miettinen SSA, Mäkinen TJ, Laaksonen I, Mäkelä K, Huhtala H, Kettunen JS, Remes V.

Hip Int. 2019 May;29(3):253-261. doi: 10.1177/1120700018798302. Epub 2018 Sep 13.

PMID:
30209970
17.

Physiotherapy pain curricula in Finland: a faculty survey.

Ehrström J, Kettunen J, Salo P.

Scand J Pain. 2018 Oct 25;18(4):593-601. doi: 10.1515/sjpain-2018-0091.

PMID:
29949518
18.

Diurnal Variations of Depression-Related Health Information Seeking: Case Study in Finland Using Google Trends Data.

Tana JC, Kettunen J, Eirola E, Paakkonen H.

JMIR Ment Health. 2018 May 23;5(2):e43. doi: 10.2196/mental.9152.

19.

NAFLD risk alleles in PNPLA3, TM6SF2, GCKR and LYPLAL1 show divergent metabolic effects.

Sliz E, Sebert S, Würtz P, Kangas AJ, Soininen P, Lehtimäki T, Kähönen M, Viikari J, Männikkö M, Ala-Korpela M, Raitakari OT, Kettunen J.

Hum Mol Genet. 2018 Jun 15;27(12):2214-2223. doi: 10.1093/hmg/ddy124.

20.

High Revision Rate for Large-head Metal-on-metal THA at a Mean of 7.1 Years: A Registry Study.

Seppänen M, Laaksonen I, Pulkkinen P, Eskelinen A, Puhto AP, Kettunen J, Leskinen J, Manninen M, Mäkelä K.

Clin Orthop Relat Res. 2018 Jun;476(6):1223-1230. doi: 10.1007/s11999.0000000000000159.

21.

What Is the Long-term Survivorship of Cruciate-retaining TKA in the Finnish Registry?

Montonen E, Laaksonen I, Matilainen M, Eskelinen A, Haapakoski J, Puhto AP, Leskinen J, Kettunen J, Manninen M, Mäkelä KT.

Clin Orthop Relat Res. 2018 Jun;476(6):1205-1211. doi: 10.1007/s11999.0000000000000202.

22.

Intraoperative Complications and Mid-Term Follow-Up of Large-Diameter Head Metal-on-Metal Total Hip Arthroplasty and Hip Resurfacing Arthroplasty.

Miettinen SSA, Mäkinen TJ, Mäkelä K, Huhtala H, Kettunen JS, Remes V.

Scand J Surg. 2018 Jun;107(2):180-186. doi: 10.1177/1457496917748220. Epub 2018 Jan 15.

PMID:
29333941
23.

Genome-Wide Association Study Implicates Atrial Natriuretic Peptide Rather Than B-Type Natriuretic Peptide in the Regulation of Blood Pressure in the General Population.

Salo PP, Havulinna AS, Tukiainen T, Raitakari O, Lehtimäki T, Kähönen M, Kettunen J, Männikkö M, Eriksson JG, Jula A, Blankenberg S, Zeller T, Salomaa V, Kristiansson K, Perola M.

Circ Cardiovasc Genet. 2017 Dec;10(6). pii: e001713. doi: 10.1161/CIRCGENETICS.117.001713.

24.

Heterozygous RFX6 protein truncating variants are associated with MODY with reduced penetrance.

Patel KA, Kettunen J, Laakso M, Stančáková A, Laver TW, Colclough K, Johnson MB, Abramowicz M, Groop L, Miettinen PJ, Shepherd MH, Flanagan SE, Ellard S, Inagaki N, Hattersley AT, Tuomi T, Cnop M, Weedon MN.

Nat Commun. 2017 Oct 12;8(1):888. doi: 10.1038/s41467-017-00895-9.

25.

An interaction map of circulating metabolites, immune gene networks, and their genetic regulation.

Nath AP, Ritchie SC, Byars SG, Fearnley LG, Havulinna AS, Joensuu A, Kangas AJ, Soininen P, Wennerström A, Milani L, Metspalu A, Männistö S, Würtz P, Kettunen J, Raitoharju E, Kähönen M, Juonala M, Palotie A, Ala-Korpela M, Ripatti S, Lehtimäki T, Abraham G, Raitakari O, Salomaa V, Perola M, Inouye M.

Genome Biol. 2017 Aug 1;18(1):146. doi: 10.1186/s13059-017-1279-y.

26.

Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure.

Marques FZ, Prestes PR, Byars SG, Ritchie SC, Würtz P, Patel SK, Booth SA, Rana I, Minoda Y, Berzins SP, Curl CL, Bell JR, Wai B, Srivastava PM, Kangas AJ, Soininen P, Ruohonen S, Kähönen M, Lehtimäki T, Raitoharju E, Havulinna A, Perola M, Raitakari O, Salomaa V, Ala-Korpela M, Kettunen J, McGlynn M, Kelly J, Wlodek ME, Lewandowski PA, Delbridge LM, Burrell LM, Inouye M, Harrap SB, Charchar FJ.

J Am Heart Assoc. 2017 Jun 14;6(6). pii: e005971. doi: 10.1161/JAHA.117.005971.

27.

Reliability of Measuring Lower-Limb-Muscle Electromyography Activity Ratio in Activities of Daily Living With Electrodes Embedded in the Clothing.

Bengs D, Jeglinsky I, Surakka J, Hellsten T, Ring J, Kettunen J.

J Sport Rehabil. 2017 Jul 1;26(4). doi: 10.1123/jsr.2017-0019. Epub 2017 Apr 19.

PMID:
28422571
28.

Progression of untreated mild thoracic Scheuermann's kyphosis - Radiographic and functional assessment after mean follow-up of 46 years.

Ristolainen L, Kettunen JA, Kujala UM, Heinonen A, Schlenzka D.

J Orthop Sci. 2017 Jul;22(4):652-657. doi: 10.1016/j.jos.2017.03.009. Epub 2017 Apr 15.

PMID:
28420562
29.

Biliary Anomalies in Patients With HNF1B Diabetes.

Kettunen JLT, Parviainen H, Miettinen PJ, Färkkilä M, Tamminen M, Salonen P, Lantto E, Tuomi T.

J Clin Endocrinol Metab. 2017 Jun 1;102(6):2075-2082. doi: 10.1210/jc.2017-00061.

PMID:
28324003
30.

Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.

Ahola-Olli AV, Würtz P, Havulinna AS, Aalto K, Pitkänen N, Lehtimäki T, Kähönen M, Lyytikäinen LP, Raitoharju E, Seppälä I, Sarin AP, Ripatti S, Palotie A, Perola M, Viikari JS, Jalkanen S, Maksimow M, Salomaa V, Salmi M, Kettunen J, Raitakari OT.

Am J Hum Genet. 2017 Jan 5;100(1):40-50. doi: 10.1016/j.ajhg.2016.11.007. Epub 2016 Dec 15.

31.

Probabilistic Evaluation of Ecological and Economic Objectives of River Basin Management Reveals a Potential Flaw in the Goal Setting of the EU Water Framework Directive.

Hjerppe T, Taskinen A, Kotamäki N, Malve O, Kettunen J.

Environ Manage. 2017 Apr;59(4):584-593. doi: 10.1007/s00267-016-0806-z. Epub 2016 Dec 16.

PMID:
27981355
32.

Metabolic profiling of pregnancy: cross-sectional and longitudinal evidence.

Wang Q, Würtz P, Auro K, Mäkinen VP, Kangas AJ, Soininen P, Tiainen M, Tynkkynen T, Jokelainen J, Santalahti K, Salmi M, Blankenberg S, Zeller T, Viikari J, Kähönen M, Lehtimäki T, Salomaa V, Perola M, Jalkanen S, Järvelin MR, Raitakari OT, Kettunen J, Lawlor DA, Ala-Korpela M.

BMC Med. 2016 Dec 13;14(1):205.

33.

Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems.

Shu L, Zhao Y, Kurt Z, Byars SG, Tukiainen T, Kettunen J, Orozco LD, Pellegrini M, Lusis AJ, Ripatti S, Zhang B, Inouye M, Mäkinen VP, Yang X.

BMC Genomics. 2016 Nov 4;17(1):874.

34.

Genome-Wide Meta-Analysis of Sciatica in Finnish Population.

Lemmelä S, Solovieva S, Shiri R, Benner C, Heliövaara M, Kettunen J, Anttila V, Ripatti S, Perola M, Seppälä I, Juonala M, Kähönen M, Salomaa V, Viikari J, Raitakari OT, Lehtimäki T, Palotie A, Viikari-Juntura E, Husgafvel-Pursiainen K.

PLoS One. 2016 Oct 20;11(10):e0163877. doi: 10.1371/journal.pone.0163877. eCollection 2016.

35.

Mobility and muscle strength in male former elite endurance and power athletes aged 66-91 years.

Manderoos S, Wasenius N, Laine MK, Kujala UM, Mälkiä E, Kaprio J, Sarna S, Bäckmand HM, Kettunen JA, Heinonen OJ, Jula AM, Aunola S, Eriksson JG.

Scand J Med Sci Sports. 2017 Nov;27(11):1283-1291. doi: 10.1111/sms.12775. Epub 2016 Oct 5.

PMID:
27704644
36.

Characterization of the metabolic profile associated with serum 25-hydroxyvitamin D: a cross-sectional analysis in population-based data.

Vogt S, Wahl S, Kettunen J, Breitner S, Kastenmüller G, Gieger C, Suhre K, Waldenberger M, Kratzsch J, Perola M, Salomaa V, Blankenberg S, Zeller T, Soininen P, Kangas AJ, Peters A, Grallert H, Ala-Korpela M, Thorand B.

Int J Epidemiol. 2016 Oct;45(5):1469-1481. Epub 2016 Sep 7.

37.

Effects of hormonal contraception on systemic metabolism: cross-sectional and longitudinal evidence.

Wang Q, Würtz P, Auro K, Morin-Papunen L, Kangas AJ, Soininen P, Tiainen M, Tynkkynen T, Joensuu A, Havulinna AS, Aalto K, Salmi M, Blankenberg S, Zeller T, Viikari J, Kähönen M, Lehtimäki T, Salomaa V, Jalkanen S, Järvelin MR, Perola M, Raitakari OT, Lawlor DA, Kettunen J, Ala-Korpela M.

Int J Epidemiol. 2016 Oct;45(5):1445-1457. Epub 2016 Aug 18.

38.

Early aseptic loosening of cementless monoblock acetabular components.

Miettinen SS, Mäkinen TJ, Laaksonen I, Mäkelä K, Huhtala H, Kettunen J, Remes V.

Int Orthop. 2017 Apr;41(4):715-722. doi: 10.1007/s00264-016-3254-8. Epub 2016 Aug 10.

PMID:
27506571
39.

Yields and Time-of-Flight Spectra of Neutral High-Rydberg Fragments at the K Edges of the CO2 Molecule.

Kivimäki A, Stråhlman C, Wasowicz TJ, Kettunen JA, Richter R.

J Phys Chem A. 2016 Jun 30;120(25):4360-7. doi: 10.1021/acs.jpca.6b04495. Epub 2016 Jun 17.

PMID:
27276338
40.

The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection.

Ritchie SC, Würtz P, Nath AP, Abraham G, Havulinna AS, Fearnley LG, Sarin AP, Kangas AJ, Soininen P, Aalto K, Seppälä I, Raitoharju E, Salmi M, Maksimow M, Männistö S, Kähönen M, Juonala M, Ripatti S, Lehtimäki T, Jalkanen S, Perola M, Raitakari O, Salomaa V, Ala-Korpela M, Kettunen J, Inouye M.

Cell Syst. 2015 Oct 28;1(4):293-301. doi: 10.1016/j.cels.2015.09.007. Epub 2015 Oct 22.

41.

Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase-Independent Effects.

Drenos F, Davey Smith G, Ala-Korpela M, Kettunen J, Würtz P, Soininen P, Kangas AJ, Dale C, Lawlor DA, Gaunt TR, Casas JP, Timpson NJ.

Circ Cardiovasc Genet. 2016 Jun;9(3):231-9. doi: 10.1161/CIRCGENETICS.115.001302. Epub 2016 Apr 25.

42.

Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses.

Aho V, Ollila HM, Kronholm E, Bondia-Pons I, Soininen P, Kangas AJ, Hilvo M, Seppälä I, Kettunen J, Oikonen M, Raitoharju E, Hyötyläinen T, Kähönen M, Viikari JS, Härmä M, Sallinen M, Olkkonen VM, Alenius H, Jauhiainen M, Paunio T, Lehtimäki T, Salomaa V, Orešič M, Raitakari OT, Ala-Korpela M, Porkka-Heiskanen T.

Sci Rep. 2016 Apr 22;6:24828. doi: 10.1038/srep24828.

43.

[Update on Current Care Guideline: Physical activity and exercise training for adults in sickness and in health].

Rauramaa R, Kukkonen-Harjula K, Arokoski J, Hohtari H, Ketola E, Kettunen J, Komulainen P, Kujala U, Laukkanen J, Pylkkänen L, Savela S, Savonen K, Tikkanen H.

Duodecim. 2016;132(5):478-9. Finnish.

PMID:
27089621
44.

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

Kettunen J, Demirkan A, Würtz P, Draisma HH, Haller T, Rawal R, Vaarhorst A, Kangas AJ, Lyytikäinen LP, Pirinen M, Pool R, Sarin AP, Soininen P, Tukiainen T, Wang Q, Tiainen M, Tynkkynen T, Amin N, Zeller T, Beekman M, Deelen J, van Dijk KW, Esko T, Hottenga JJ, van Leeuwen EM, Lehtimäki T, Mihailov E, Rose RJ, de Craen AJ, Gieger C, Kähönen M, Perola M, Blankenberg S, Savolainen MJ, Verhoeven A, Viikari J, Willemsen G, Boomsma DI, van Duijn CM, Eriksson J, Jula A, Järvelin MR, Kaprio J, Metspalu A, Raitakari O, Salomaa V, Slagboom PE, Waldenberger M, Ripatti S, Ala-Korpela M.

Nat Commun. 2016 Mar 23;7:11122. doi: 10.1038/ncomms11122.

45.

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase.

Würtz P, Wang Q, Soininen P, Kangas AJ, Fatemifar G, Tynkkynen T, Tiainen M, Perola M, Tillin T, Hughes AD, Mäntyselkä P, Kähönen M, Lehtimäki T, Sattar N, Hingorani AD, Casas JP, Salomaa V, Kivimäki M, Järvelin MR, Davey Smith G, Vanhala M, Lawlor DA, Raitakari OT, Chaturvedi N, Kettunen J, Ala-Korpela M.

J Am Coll Cardiol. 2016 Mar 15;67(10):1200-1210. doi: 10.1016/j.jacc.2015.12.060.

46.

Insomnia does not mediate or modify the association between MTNR1B risk variant rs10830963 and glucose levels.

Ollila HM, Kronholm E, Kettunen J, Silander K, Perola M, Porkka-Heiskanen T, Salomaa V, Paunio T.

Diabetologia. 2016 May;59(5):1070-2. doi: 10.1007/s00125-016-3893-8. Epub 2016 Feb 24. No abstract available.

PMID:
26912228
47.

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health.

Laurila PP, Soronen J, Kooijman S, Forsström S, Boon MR, Surakka I, Kaiharju E, Coomans CP, Van Den Berg SA, Autio A, Sarin AP, Kettunen J, Tikkanen E, Manninen T, Metso J, Silvennoinen R, Merikanto K, Ruuth M, Perttilä J, Mäkelä A, Isomi A, Tuomainen AM, Tikka A, Ramadan UA, Seppälä I, Lehtimäki T, Eriksson J, Havulinna A, Jula A, Karhunen PJ, Salomaa V, Perola M, Ehnholm C, Lee-Rueckert M, Van Eck M, Roivainen A, Taskinen MR, Peltonen L, Mervaala E, Jalanko A, Hohtola E, Olkkonen VM, Ripatti S, Kovanen PT, Rensen PC, Suomalainen A, Jauhiainen M.

Sci Transl Med. 2016 Jan 27;8(323):323ra13. doi: 10.1126/scitranslmed.aad0015.

PMID:
26819196
48.

Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential.

Kyttälä A, Moraghebi R, Valensisi C, Kettunen J, Andrus C, Pasumarthy KK, Nakanishi M, Nishimura K, Ohtaka M, Weltner J, Van Handel B, Parkkonen O, Sinisalo J, Jalanko A, Hawkins RD, Woods NB, Otonkoski T, Trokovic R.

Stem Cell Reports. 2016 Feb 9;6(2):200-12. doi: 10.1016/j.stemcr.2015.12.009. Epub 2016 Jan 14.

49.

Risk factors for intraoperative calcar fracture in cementless total hip arthroplasty.

Miettinen SS, Mäkinen TJ, Kostensalo I, Mäkelä K, Huhtala H, Kettunen JS, Remes V.

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