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Items: 1 to 50 of 403

1.

Olfactory and gustatory functioning and food preferences of patients with Alzheimer's disease and mild cognitive impairment compared to controls: the NUDAD project.

Doorduijn AS, de van der Schueren MAE, van de Rest O, de Leeuw FA, Fieldhouse JLP, Kester MI, Teunissen CE, Scheltens P, van der Flier WM, Visser M, Boesveldt S.

J Neurol. 2019 Oct 8. doi: 10.1007/s00415-019-09561-0. [Epub ahead of print]

PMID:
31595376
2.

Hematopoietic Stem Cell Transplantation to Treat Leukodystrophies: Clinical Practice Guidelines from the Hunter's Hope Leukodystrophy Care Network.

Page KM, Stenger EO, Connelly JA, Shyr D, West T, Wood S, Case L, Kester M, Shim S, Hammond L, Hammond M, Webb C, Biffi A, Bambach B, Fatemi A, Kurtzberg J.

Biol Blood Marrow Transplant. 2019 Sep 6. pii: S1083-8791(19)30571-3. doi: 10.1016/j.bbmt.2019.09.003. [Epub ahead of print]

PMID:
31499213
3.

Sphingolipid metabolism determines the therapeutic efficacy of nanoliposomal ceramide in acute myeloid leukemia.

Barth BM, Wang W, Toran PT, Fox TE, Annageldiyev C, Ondrasik RM, Keasey NR, Brown TJ, Devine VG, Sullivan EC, Cote AL, Papakotsi V, Tan SF, Shanmugavelandy SS, Deering TG, Needle DB, Stern ST, Zhu J, Liao J, Viny AD, Feith DJ, Levine RL, Wang HG, Loughran TP Jr, Sharma A, Kester M, Claxton DF.

Blood Adv. 2019 Sep 10;3(17):2598-2603. doi: 10.1182/bloodadvances.2018021295. No abstract available.

4.

Geriatric assessment of patients treated for cutaneous head and neck malignancies in a tertiary referral center: Predictors of postoperative complications.

de Vries J, Heirman AN, Bras L, Plaat BEC, Rácz E, van Kester MS, Festen S, de Bock GH, van der Laan BFAM, Halmos GB.

Eur J Surg Oncol. 2019 Aug 10. pii: S0748-7983(19)30620-1. doi: 10.1016/j.ejso.2019.08.008. [Epub ahead of print]

PMID:
31427138
5.

Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells.

Kao LP, Morad SAF, Davis TS, MacDougall MR, Kassai M, Abdelmageed N, Fox TE, Kester M, Loughran TP Jr, Abad JL, Fabrias G, Tan SF, Feith DJ, Claxton DF, Spiegel S, Fisher-Wellman KH, Cabot MC.

J Lipid Res. 2019 Sep;60(9):1590-1602. doi: 10.1194/jlr.RA119000251. Epub 2019 Jul 30.

PMID:
31363040
6.

Conductance-Based Biophysical Distinction and Microfluidic Enrichment of Nanovesicles Derived from Pancreatic Tumor Cells of Varying Invasiveness.

Moore JH, Varhue WB, Su YH, Linton SS, Farmehini V, Fox TE, Matters GL, Kester M, Swami NS.

Anal Chem. 2019 Aug 20;91(16):10424-10431. doi: 10.1021/acs.analchem.8b05745. Epub 2019 Aug 1.

PMID:
31333013
7.

Associations of AD Biomarkers and Cognitive Performance with Nutritional Status: The NUDAD Project.

Doorduijn AS, Visser M, van de Rest O, Kester MI, de Leeuw FA, Boesveldt S, Fieldhouse JLP, van den Heuvel EGHM, Teunissen CE, Scheltens P, van der Flier WM, de van der Schueren MAE.

Nutrients. 2019 May 23;11(5). pii: E1161. doi: 10.3390/nu11051161.

8.

Pivotal role of mitophagy in response of acute myelogenous leukemia to a ceramide-tamoxifen-containing drug regimen.

Morad SAF, MacDougall MR, Abdelmageed N, Kao LP, Feith DJ, Tan SF, Kester M, Loughran TP Jr, Wang HG, Cabot MC.

Exp Cell Res. 2019 Aug 15;381(2):256-264. doi: 10.1016/j.yexcr.2019.05.021. Epub 2019 May 18.

PMID:
31112736
9.

Dietary Patterns Are Related to Clinical Characteristics in Memory Clinic Patients with Subjective Cognitive Decline: The SCIENCe Project.

Wesselman LMP, Doorduijn AS, de Leeuw FA, Verfaillie SCJ, van Leeuwenstijn-Koopman M, Slot RER, Kester MI, Prins ND, van de Rest O, de van der Schueren MAE, Scheltens P, Sikkes SAM, van der Flier WM.

Nutrients. 2019 May 11;11(5). pii: E1057. doi: 10.3390/nu11051057.

10.

ApoE and clusterin CSF levels influence associations between APOE genotype and changes in CSF tau, but not CSF Aβ42, levels in non-demented elderly.

Slot RER, Kester MI, Van Harten AC, Jongbloed W, Bouwman FH, Teunissen CE, Scheltens P, van der Flier WM, Veerhuis R.

Neurobiol Aging. 2019 Jul;79:101-109. doi: 10.1016/j.neurobiolaging.2019.02.017. Epub 2019 Mar 1.

PMID:
31029938
11.

Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation.

Tan SF, Dunton W, Liu X, Fox TE, Morad SAF, Desai D, Doi K, Conaway MR, Amin S, Claxton DF, Wang HG, Kester M, Cabot MC, Feith DJ, Loughran TP Jr.

J Lipid Res. 2019 Jun;60(6):1078-1086. doi: 10.1194/jlr.M091876. Epub 2019 Apr 8.

PMID:
30962310
12.

Glucosylceramidase Maintains Influenza Virus Infection by Regulating Endocytosis.

Drews K, Calgi MP, Harrison WC, Drews CM, Costa-Pinheiro P, Shaw JJP, Jobe KA, Nelson EA, Han JD, Fox T, White JM, Kester M.

J Virol. 2019 May 29;93(12). pii: e00017-19. doi: 10.1128/JVI.00017-19. Print 2019 Jun 15.

13.

Pharmacokinetic and pharmacodynamic considerations in the treatment of the elderly patient with hypertension.

Peeters LEJ, Kester MP, Feyz L, Van Den Bemt PMLA, Koch BCP, Van Gelder T, Versmissen J.

Expert Opin Drug Metab Toxicol. 2019 Apr;15(4):287-297. doi: 10.1080/17425255.2019.1588249. Epub 2019 Mar 16. Review.

PMID:
30880496
14.

Expression of the SNAI2 transcriptional repressor is regulated by C16-ceramide.

Lu P, White-Gilbertson S, Nganga R, Kester M, Voelkel-Johnson C.

Cancer Biol Ther. 2019;20(6):922-930. doi: 10.1080/15384047.2019.1579962. Epub 2019 Mar 5.

PMID:
30836822
15.

Tissue-sparing properties of Mohs micrographic surgery for infiltrative basal cell carcinoma.

van Kester MS, Goeman JJ, Genders RE.

J Am Acad Dermatol. 2019 Jun;80(6):1700-1703. doi: 10.1016/j.jaad.2019.01.057. Epub 2019 Jan 31.

PMID:
30710602
16.

Mutated nucleophosmin 1 as immunotherapy target in acute myeloid leukemia.

van der Lee DI, Reijmers RM, Honders MW, Hagedoorn RS, de Jong RC, Kester MG, van der Steen DM, de Ru AH, Kweekel C, Bijen HM, Jedema I, Veelken H, van Veelen PA, Heemskerk MH, Falkenburg JHF, Griffioen M.

J Clin Invest. 2019 Feb 1;129(2):774-785. doi: 10.1172/JCI97482. Epub 2019 Jan 14.

17.

Remission of psoriasis during treatment with sorafenib.

van Kester MS, Luelmo SAC, Vermeer MH, Blank C, van Doorn R.

JAAD Case Rep. 2018 Nov 14;4(10):1065-1067. doi: 10.1016/j.jdcr.2018.09.009. eCollection 2018 Nov. No abstract available.

18.

Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages.

Linton SS, Abraham T, Liao J, Clawson GA, Butler PJ, Fox T, Kester M, Matters GL.

PLoS One. 2018 Nov 1;13(11):e0206759. doi: 10.1371/journal.pone.0206759. eCollection 2018.

19.

Computational and Experimental Investigation of Janus-like Monolayers on Ultrasmall Noble Metal Nanoparticles.

Merz SN, Farrell ZJ, Pearring J, Hoover E, Kester M, Egorov SA, Green DL, DuBay KH.

ACS Nano. 2018 Nov 27;12(11):11031-11040. doi: 10.1021/acsnano.8b05188. Epub 2018 Oct 26.

PMID:
30347139
20.

Ex vivo AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8+ T cells for adoptive immunotherapy.

Mousset CM, Hobo W, Ji Y, Fredrix H, De Giorgi V, Allison RD, Kester MGD, Falkenburg JHF, Schaap NPM, Jansen JH, Gattinoni L, Dolstra H, van der Waart AB.

Oncoimmunology. 2018 Aug 6;7(10):e1488565. doi: 10.1080/2162402X.2018.1488565. eCollection 2018.

21.

Identification of non-mutated neoantigens presented by TAP-deficient tumors.

Marijt KA, Blijleven L, Verdegaal EME, Kester MG, Kowalewski DJ, Rammensee HG, Stevanović S, Heemskerk MHM, van der Burg SH, van Hall T.

J Exp Med. 2018 Sep 3;215(9):2325-2337. doi: 10.1084/jem.20180577. Epub 2018 Aug 16.

22.

Novel Sphingolipid-Based Cancer Therapeutics in the Personalized Medicine Era.

Shaw J, Costa-Pinheiro P, Patterson L, Drews K, Spiegel S, Kester M.

Adv Cancer Res. 2018;140:327-366. doi: 10.1016/bs.acr.2018.04.016. Epub 2018 Jun 19. Review.

23.

Therapeutic Effect of Blueberry Extracts for Acute Myeloid Leukemia.

McGill CM, Brown TJ, Cheng YY, Fisher LN, Shanmugavelandy SS, Gustafson SJ, Dunlap KL, Lila MA, Kester M, Toran PT, Claxton DF, Barth BM.

Int J Biopharm Sci. 2018 Jan;1(1). pii: 102. Epub 2018 Jan 2.

24.

A breathtaking DRESS due to amoxicillin-clavulanate presenting as polymorphic eruption of the pregnancy.

van Kester MS, Langeveld TJC, Bouwsma H, van Rees JB, Holman ER, Teng YKO, van Zuuren EJ.

J Eur Acad Dermatol Venereol. 2018 Dec;32(12):e436-e437. doi: 10.1111/jdv.14956. Epub 2018 May 3. No abstract available.

PMID:
29569759
25.

The simultaneous isolation of multiple high and low frequent T-cell populations from donor peripheral blood mononuclear cells using the major histocompatibility complex I-Streptamer isolation technology.

Roex MCJ, Hageman L, Heemskerk MT, Veld SAJ, van Liempt E, Kester MGD, Germeroth L, Stemberger C, Falkenburg JHF, Jedema I.

Cytotherapy. 2018 Apr;20(4):543-555. doi: 10.1016/j.jcyt.2018.01.008. Epub 2018 Feb 12.

PMID:
29449085
26.

Lymphangitis carcinomatosa of a cutaneous squamous cell carcinoma.

van Kester MS, Genders RE, Quint KD.

BMJ Case Rep. 2018 Feb 8;2018. pii: bcr-2017-222923. doi: 10.1136/bcr-2017-222923. No abstract available.

PMID:
29437807
27.

Nanoliposome C6-Ceramide Increases the Anti-tumor Immune Response and Slows Growth of Liver Tumors in Mice.

Li G, Liu D, Kimchi ET, Kaifi JT, Qi X, Manjunath Y, Liu X, Deering T, Avella DM, Fox T, Rockey DC, Schell TD, Kester M, Staveley-O'Carroll KF.

Gastroenterology. 2018 Mar;154(4):1024-1036.e9. doi: 10.1053/j.gastro.2017.10.050. Epub 2018 Jan 31.

28.

Agminated Spitz naevi or metastatic spitzoid melanoma?

van Kester MS, Eggen C, Beishuizen A, Kukutsch NA.

Australas J Dermatol. 2018 Aug;59(3):e234-e235. doi: 10.1111/ajd.12781. Epub 2018 Feb 5. No abstract available.

29.

STAT3 mediates C6-ceramide-induced cell death in chronic lymphocytic leukemia.

Doshi UA, Shaw J, Fox TE, Claxton DF, Loughran TP, Kester M.

Signal Transduct Target Ther. 2017 Oct 27;2:17051. doi: 10.1038/sigtrans.2017.51. eCollection 2017.

30.

Specific T Cell Responses against Minor Histocompatibility Antigens Cannot Generally Be Explained by Absence of Their Allelic Counterparts on the Cell Surface.

Bijen HM, Hassan C, Kester MGD, Janssen GMC, Hombrink P, de Ru AH, Drijfhout JW, Meiring HD, de Jong AP, Falkenburg JHF, Jimenez CR, Heemskerk MHM, van Veelen PA.

Proteomics. 2018 Jun;18(12):e1700250. doi: 10.1002/pmic.201700250. Epub 2018 Feb 23.

PMID:
29251415
31.

Increased Coexpression of PD-1, TIGIT, and KLRG-1 on Tumor-Reactive CD8+ T Cells During Relapse after Allogeneic Stem Cell Transplantation.

Hutten TJA, Norde WJ, Woestenenk R, Wang RC, Maas F, Kester M, Falkenburg JHF, Berglund S, Luznik L, Jansen JH, Schaap N, Dolstra H, Hobo W.

Biol Blood Marrow Transplant. 2018 Apr;24(4):666-677. doi: 10.1016/j.bbmt.2017.11.027. Epub 2017 Dec 26.

32.

Ceramide Nanoliposomes as a MLKL-Dependent, Necroptosis-Inducing, Chemotherapeutic Reagent in Ovarian Cancer.

Zhang X, Kitatani K, Toyoshima M, Ishibashi M, Usui T, Minato J, Egiz M, Shigeta S, Fox T, Deering T, Kester M, Yaegashi N.

Mol Cancer Ther. 2018 Jan;17(1):50-59. doi: 10.1158/1535-7163.MCT-17-0173. Epub 2017 Oct 27.

33.

Novel uses of bilateral advancement flaps for tip defects on the nose: Part I.

van Kester MS, Genders RE.

J Am Acad Dermatol. 2018 Apr;78(4):e91-e92. doi: 10.1016/j.jaad.2017.09.057. Epub 2017 Oct 6. No abstract available.

PMID:
28989110
34.

Novel uses of bilateral advancement flaps for tip defects on the nose: Part II.

Genders RE, van Kester MS.

J Am Acad Dermatol. 2018 Apr;78(4):e93-e94. doi: 10.1016/j.jaad.2017.09.058. Epub 2017 Oct 5. No abstract available.

PMID:
28989108
35.

Blood-based metabolic signatures in Alzheimer's disease.

de Leeuw FA, Peeters CFW, Kester MI, Harms AC, Struys EA, Hankemeier T, van Vlijmen HWT, van der Lee SJ, van Duijn CM, Scheltens P, Demirkan A, van de Wiel MA, van der Flier WM, Teunissen CE.

Alzheimers Dement (Amst). 2017 Sep 6;8:196-207. doi: 10.1016/j.dadm.2017.07.006. eCollection 2017.

36.

Liposomal Delivery of Diacylglycerol Lipase-Beta Inhibitors to Macrophages Dramatically Enhances Selectivity and Efficacy in Vivo.

Shin M, Snyder HW, Donvito G, Schurman LD, Fox TE, Lichtman AH, Kester M, Hsu KL.

Mol Pharm. 2018 Mar 5;15(3):721-728. doi: 10.1021/acs.molpharmaceut.7b00657. Epub 2017 Sep 13.

37.

SKI-178: A Multitargeted Inhibitor of Sphingosine Kinase and Microtubule Dynamics Demonstrating Therapeutic Efficacy in Acute Myeloid Leukemia Models.

Hengst JA, Dick TE, Sharma A, Doi K, Hegde S, Tan SF, Geffert LM, Fox TE, Sharma AK, Desai D, Amin S, Kester M, Loughran TP, Paulson RF, Claxton DF, Wang HG, Yun JK.

Cancer Transl Med. 2017 Jul-Aug;3(4):109-121. doi: 10.4103/ctm.ctm_7_17. Epub 2017 Aug 14.

38.

The use of nanoparticulates to treat breast cancer.

Tang X, Loc WS, Dong C, Matters GL, Butler PJ, Kester M, Meyers C, Jiang Y, Adair JH.

Nanomedicine (Lond). 2017 Oct;12(19):2367-2388. doi: 10.2217/nnm-2017-0202. Epub 2017 Sep 4. Review.

39.

Therapeutic implications of bioactive sphingolipids: A focus on colorectal cancer.

Camp ER, Patterson LD, Kester M, Voelkel-Johnson C.

Cancer Biol Ther. 2017 Sep 2;18(9):640-650. doi: 10.1080/15384047.2017.1345396. Epub 2017 Jul 7. Review.

40.

Effective encapsulation and biological activity of phosphorylated chemotherapeutics in calcium phosphosilicate nanoparticles for the treatment of pancreatic cancer.

Loc WS, Linton SS, Wilczynski ZR, Matters GL, McGovern CO, Abraham T, Fox T, Gigliotti CM, Tang X, Tabakovic A, Martin JA, Clawson GA, Smith JP, Butler PJ, Kester M, Adair JH.

Nanomedicine. 2017 Oct;13(7):2313-2324. doi: 10.1016/j.nano.2017.06.017. Epub 2017 Jul 1.

41.

Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection.

Vijayan M, Xia C, Song YE, Ngo H, Studstill CJ, Drews K, Fox TE, Johnson MC, Hiscott J, Kester M, Alexander S, Hahm B.

J Immunol. 2017 Jul 15;199(2):677-687. doi: 10.4049/jimmunol.1601959. Epub 2017 Jun 9.

42.

A phase I/II minor histocompatibility antigen-loaded dendritic cell vaccination trial to safely improve the efficacy of donor lymphocyte infusions in myeloma.

Franssen LE, Roeven MWH, Hobo W, Doorn R, Oostvogels R, Falkenburg JHF, van de Donk NW, Kester MGD, Fredrix H, Westinga K, Slaper-Cortenbach I, Spierings E, Kersten MJ, Dolstra H, Mutis T, Schaap N, Lokhorst HM.

Bone Marrow Transplant. 2017 Oct;52(10):1378-1383. doi: 10.1038/bmt.2017.118. Epub 2017 Jun 5.

PMID:
28581468
43.

Hematopoietic stem cell-derived myeloid and plasmacytoid DC-based vaccines are highly potent inducers of tumor-reactive T cell and NK cell responses ex vivo.

Thordardottir S, Schaap N, Louer E, Kester MG, Falkenburg JH, Jansen J, Radstake TR, Hobo W, Dolstra H.

Oncoimmunology. 2017 Feb 6;6(3):e1285991. doi: 10.1080/2162402X.2017.1285991. eCollection 2017.

44.

Role of P-glycoprotein inhibitors in ceramide-based therapeutics for treatment of cancer.

Morad SAF, Davis TS, MacDougall MR, Tan SF, Feith DJ, Desai DH, Amin SG, Kester M, Loughran TP Jr, Cabot MC.

Biochem Pharmacol. 2017 Apr 15;130:21-33. doi: 10.1016/j.bcp.2017.02.002. Epub 2017 Feb 9.

45.

The wingman flap: Bilateral closure of a supra-tip defect of the nose.

Kouwenhoven ST, van Kester MS, Genders RE.

J Am Acad Dermatol. 2017 Feb;76(2):e57-e58. doi: 10.1016/j.jaad.2016.08.037. No abstract available.

PMID:
28089014
46.

TCR-based therapy for multiple myeloma and other B-cell malignancies targeting intracellular transcription factor BOB1.

Jahn L, Hombrink P, Hagedoorn RS, Kester MG, van der Steen DM, Rodriguez T, Pentcheva-Hoang T, de Ru AH, Schoonakker MP, Meeuwsen MH, Griffioen M, van Veelen PA, Falkenburg JH, Heemskerk MH.

Blood. 2017 Mar 9;129(10):1284-1295. doi: 10.1182/blood-2016-09-737536. Epub 2017 Jan 4.

PMID:
28053195
47.

Apolipoprotein A1 in Cerebrospinal Fluid and Plasma and Progression to Alzheimer's Disease in Non-Demented Elderly.

Slot RE, Van Harten AC, Kester MI, Jongbloed W, Bouwman FH, Teunissen CE, Scheltens P, Veerhuis R, van der Flier WM.

J Alzheimers Dis. 2017;56(2):687-697. doi: 10.3233/JAD-151068.

PMID:
28035918
48.

Acid ceramidase is upregulated in AML and represents a novel therapeutic target.

Tan SF, Liu X, Fox TE, Barth BM, Sharma A, Turner SD, Awwad A, Dewey A, Doi K, Spitzer B, Shah MV, Morad SA, Desai D, Amin S, Zhu J, Liao J, Yun J, Kester M, Claxton DF, Wang HG, Cabot MC, Schuchman EH, Levine RL, Feith DJ, Loughran TP Jr.

Oncotarget. 2016 Dec 13;7(50):83208-83222. doi: 10.18632/oncotarget.13079.

49.

Determinants of bird conservation-action implementation and associated population trends of threatened species.

Luther DA, Brooks TM, Butchart SH, Hayward MW, Kester ME, Lamoreux J, Upgren A.

Conserv Biol. 2016 Dec;30(6):1338-1346. doi: 10.1111/cobi.12757. Epub 2016 Aug 24.

PMID:
27197021
50.

Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking.

Young MM, Takahashi Y, Fox TE, Yun JK, Kester M, Wang HG.

Cell Rep. 2016 Nov 1;17(6):1532-1545. doi: 10.1016/j.celrep.2016.10.019.

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