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Items: 1 to 50 of 275

1.

Inhibition of immune checkpoints prevents injury-induced heterotopic ossification.

Kan C, Yang J, Na D, Xu Y, Yang B, Zhao H, Lu H, Li Y, Zhang K, McGuire TL, Kessler JA, Kan L.

Bone Res. 2019 Nov 1;7:33. doi: 10.1038/s41413-019-0074-7. eCollection 2019.

2.

Localized electroporation with track-etched membranes.

Nathamgari SSP, Mukherjee P, Kessler JA, Espinosa HD.

Proc Natl Acad Sci U S A. 2019 Oct 29. pii: 201911718. doi: 10.1073/pnas.1911718116. [Epub ahead of print] No abstract available.

PMID:
31662467
3.

BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma.

Sachdeva R, Wu M, Johnson K, Kim H, Celebre A, Shahzad U, Graham MS, Kessler JA, Chuang JH, Karamchandani J, Bredel M, Verhaak R, Das S.

Sci Rep. 2019 Oct 10;9(1):14569. doi: 10.1038/s41598-019-51270-1.

4.

Spinal Cord Injury Results in Chronic Mechanical Stiffening.

Cooper JG, Sicard D, Sharma S, Van Gulden S, McGuire TL, Cajiao MP, Tschumperlin DJ, Kessler JA.

J Neurotrauma. 2019 Oct 18. doi: 10.1089/neu.2019.6540. [Epub ahead of print]

PMID:
31516087
5.

Activating newborn neurons suppresses depression and anxiety-like behaviors.

Tunc-Ozcan E, Peng CY, Zhu Y, Dunlop SR, Contractor A, Kessler JA.

Nat Commun. 2019 Aug 21;10(1):3768. doi: 10.1038/s41467-019-11641-8.

6.

Bmp signaling in molar cusp formation.

Meguro F, Porntaveetus T, Kawasaki M, Kawasaki K, Yamada A, Kakihara Y, Saeki M, Tabeta K, Kessler JA, Maeda T, Ohazama A.

Gene Expr Patterns. 2019 Jun;32:67-71. doi: 10.1016/j.gep.2019.04.002. Epub 2019 Apr 11.

PMID:
30980961
7.

Neuronal apolipoprotein E4 increases cell death and phosphorylated tau release in alzheimer disease.

Wadhwani AR, Affaneh A, Van Gulden S, Kessler JA.

Ann Neurol. 2019 May;85(5):726-739. doi: 10.1002/ana.25455. Epub 2019 Mar 27.

PMID:
30840313
8.

Corrigendum to 'Conserved signaling pathways underlying heterotopic ossification' [Bone, 109, April 2018, 43-48].

Kan C, Chen L, Hu Y, Ding N, Lu H, Li Y, Kessler JA, Kan L.

Bone. 2019 May;122:254. doi: 10.1016/j.bone.2019.02.023. Epub 2019 Feb 28. No abstract available.

PMID:
30826307
9.

BMP-dependent, injury-induced stem cell niche as a mechanism of heterotopic ossification.

Kan C, Ding N, Yang J, Tan Z, McGuire TL, Lu H, Zhang K, Berger DMP, Kessler JA, Kan L.

Stem Cell Res Ther. 2019 Jan 11;10(1):14. doi: 10.1186/s13287-018-1107-7.

10.

Combined Numerical and Experimental Investigation of Localized Electroporation-Based Cell Transfection and Sampling.

Mukherjee P, Nathamgari SSP, Kessler JA, Espinosa HD.

ACS Nano. 2018 Dec 26;12(12):12118-12128. doi: 10.1021/acsnano.8b05473. Epub 2018 Nov 27.

11.

Wnt signaling in physiological and pathological bone formation.

Tan Z, Ding N, Lu H, Kessler JA, Kan L.

Histol Histopathol. 2019 Apr;34(4):303-312. doi: 10.14670/HH-18-062. Epub 2018 Nov 13. Review.

PMID:
30422303
12.

Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms.

Kawasaki M, Kawasaki K, Meguro F, Yamada A, Ishikawa R, Porntaveetus T, Blackburn J, Otsuka-Tanaka Y, Saito N, Ota MS, Sharpe PT, Kessler JA, Herz J, Cobourne MT, Maeda T, Ohazama A.

PLoS One. 2018 Sep 20;13(9):e0204126. doi: 10.1371/journal.pone.0204126. eCollection 2018.

13.

Full Factorial Microfluidic Designs and Devices for Parallelizing Human Pluripotent Stem Cell Differentiation.

Chadly DM, Oleksijew AM, Coots KS, Fernandez JJ, Kobayashi S, Kessler JA, Matsuoka AJ.

SLAS Technol. 2019 Feb;24(1):41-54. doi: 10.1177/2472630318783497. Epub 2018 Jul 11.

PMID:
29995450
14.

Genome-wide methylomic and transcriptomic analyses identify subtype-specific epigenetic signatures commonly dysregulated in glioma stem cells and glioblastoma.

Pangeni RP, Zhang Z, Alvarez AA, Wan X, Sastry N, Lu S, Shi T, Huang T, Lei CX, James CD, Kessler JA, Brennan CW, Nakano I, Lu X, Hu B, Zhang W, Cheng SY.

Epigenetics. 2018;13(4):432-448. doi: 10.1080/15592294.2018.1469892. Epub 2018 Aug 6.

15.

Fibronectin EDA forms the chronic fibrotic scar after contusive spinal cord injury.

Cooper JG, Jeong SJ, McGuire TL, Sharma S, Wang W, Bhattacharyya S, Varga J, Kessler JA.

Neurobiol Dis. 2018 Aug;116:60-68. doi: 10.1016/j.nbd.2018.04.014. Epub 2018 Apr 27.

16.

BMP-Responsive Protease HtrA1 Is Differentially Expressed in Astrocytes and Regulates Astrocytic Development and Injury Response.

Chen J, Van Gulden S, McGuire TL, Fleming AC, Oka C, Kessler JA, Peng CY.

J Neurosci. 2018 Apr 11;38(15):3840-3857. doi: 10.1523/JNEUROSCI.2031-17.2018. Epub 2018 Feb 26.

17.

Developmental profiling of microRNAs in the human embryonic inner ear.

Chadly DM, Best J, Ran C, Bruska M, Woźniak W, Kempisty B, Schwartz M, LaFleur B, Kerns BJ, Kessler JA, Matsuoka AJ.

PLoS One. 2018 Jan 26;13(1):e0191452. doi: 10.1371/journal.pone.0191452. eCollection 2018.

18.

Targeted Knockdown of Bone Morphogenetic Protein Signaling within Neural Progenitors Protects the Brain and Improves Motor Function following Postnatal Hypoxia-Ischemia.

Dettman RW, Birch D, Fernando A, Kessler JA, Dizon MLV.

Dev Neurosci. 2018;40(1):23-38. doi: 10.1159/000485379. Epub 2018 Jan 12.

19.

Creating a stem cell niche in the inner ear using self-assembling peptide amphiphiles.

Matsuoka AJ, Sayed ZA, Stephanopoulos N, Berns EJ, Wadhwani AR, Morrissey ZD, Chadly DM, Kobayashi S, Edelbrock AN, Mashimo T, Miller CA, McGuire TL, Stupp SI, Kessler JA.

PLoS One. 2017 Dec 28;12(12):e0190150. doi: 10.1371/journal.pone.0190150. eCollection 2017.

20.

MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma.

Huang T, Kim CK, Alvarez AA, Pangeni RP, Wan X, Song X, Shi T, Yang Y, Sastry N, Horbinski CM, Lu S, Stupp R, Kessler JA, Nishikawa R, Nakano I, Sulman EP, Lu X, James CD, Yin XM, Hu B, Cheng SY.

Cancer Cell. 2017 Dec 11;32(6):840-855.e8. doi: 10.1016/j.ccell.2017.11.005.

21.

Design, Assembly, Production, and Transfection of Synthetic Modified mRNA.

Oh S, Kessler JA.

Methods. 2018 Jan 15;133:29-43. doi: 10.1016/j.ymeth.2017.10.008. Epub 2017 Nov 7.

22.

NI(ii) phosphine and phosphide complexes supported by a PNP-pyrrole pincer ligand.

Kessler JA, Iluc VM.

Dalton Trans. 2017 Sep 28;46(36):12125-12131. doi: 10.1039/c7dt02784b. Epub 2017 Sep 4.

PMID:
28869266
23.

Intravenous immune-modifying nanoparticles as a therapy for spinal cord injury in mice.

Jeong SJ, Cooper JG, Ifergan I, McGuire TL, Xu D, Hunter Z, Sharma S, McCarthy D, Miller SD, Kessler JA.

Neurobiol Dis. 2017 Dec;108:73-82. doi: 10.1016/j.nbd.2017.08.006. Epub 2017 Aug 18.

24.

Gli1-labeled adult mesenchymal stem/progenitor cells and hedgehog signaling contribute to endochondral heterotopic ossification.

Kan C, Chen L, Hu Y, Ding N, Li Y, McGuire TL, Lu H, Kessler JA, Kan L.

Bone. 2018 Apr;109:71-79. doi: 10.1016/j.bone.2017.06.014. Epub 2017 Jun 21.

25.

Conserved signaling pathways underlying heterotopic ossification.

Kan C, Chen L, Hu Y, Ding N, Lu H, Li Y, Kessler JA, Kan L.

Bone. 2018 Apr;109:43-48. doi: 10.1016/j.bone.2017.04.014. Epub 2017 Apr 25. Review. Erratum in: Bone. 2019 May;122:254.

26.

Microenvironmental factors that regulate mesenchymal stem cells: lessons learned from the study of heterotopic ossification.

Kan C, Chen L, Hu Y, Lu H, Li Y, Kessler JA, Kan L.

Histol Histopathol. 2017 Oct;32(10):977-985. doi: 10.14670/HH-11-890. Epub 2017 Mar 22. Review.

27.

Erratum to: SDF1 in the dorsal corticospinal tract promotes CXCR4+ cell migration after spinal cord injury.

Tysseling VM, Mithal DS, Sahni V, Birch D, Jung H, Miller RJ, Kessler JA.

J Neuroinflammation. 2017 Feb 14;14(1):35. doi: 10.1186/s12974-017-0810-0. No abstract available.

28.

Directed Differentiation of Human Embryonic Stem Cells Toward Placode-Derived Spiral Ganglion-Like Sensory Neurons.

Matsuoka AJ, Morrissey ZD, Zhang C, Homma K, Belmadani A, Miller CA, Chadly DM, Kobayashi S, Edelbrock AN, Tanaka-Matakatsu M, Whitlon DS, Lyass L, McGuire TL, Stupp SI, Kessler JA.

Stem Cells Transl Med. 2017 Mar;6(3):923-936. doi: 10.1002/sctm.16-0032. Epub 2016 Dec 10.

29.

Open label study to assess the safety of VM202 in subjects with amyotrophic lateral sclerosis.

Sufit RL, Ajroud-Driss S, Casey P, Kessler JA.

Amyotroph Lateral Scler Frontotemporal Degener. 2017 May;18(3-4):269-278. doi: 10.1080/21678421.2016.1259334. Epub 2017 Feb 6.

PMID:
28166654
30.

TGF-β Family Signaling in Neural and Neuronal Differentiation, Development, and Function.

Meyers EA, Kessler JA.

Cold Spring Harb Perspect Biol. 2017 Aug 1;9(8). pii: a022244. doi: 10.1101/cshperspect.a022244. Review.

31.

Hippocampal bone morphogenetic protein signaling mediates behavioral effects of antidepressant treatment.

Brooker SM, Gobeske KT, Chen J, Peng CY, Kessler JA.

Mol Psychiatry. 2017 Jun;22(6):910-919. doi: 10.1038/mp.2016.160. Epub 2016 Oct 4.

32.

β1-integrin restricts astrocytic differentiation of adult hippocampal neural stem cells.

Brooker SM, Bond AM, Peng CY, Kessler JA.

Glia. 2016 Jul;64(7):1235-51. doi: 10.1002/glia.22996. Epub 2016 May 5.

PMID:
27145730
33.

A tenascin-C mimetic peptide amphiphile nanofiber gel promotes neurite outgrowth and cell migration of neurosphere-derived cells.

Berns EJ, Álvarez Z, Goldberger JE, Boekhoven J, Kessler JA, Kuhn HG, Stupp SI.

Acta Biomater. 2016 Jun;37:50-8. doi: 10.1016/j.actbio.2016.04.010. Epub 2016 Apr 7.

34.

Increased bone morphogenetic protein signaling contributes to age-related declines in neurogenesis and cognition.

Meyers EA, Gobeske KT, Bond AM, Jarrett JC, Peng CY, Kessler JA.

Neurobiol Aging. 2016 Feb;38:164-175. doi: 10.1016/j.neurobiolaging.2015.10.035. Epub 2015 Nov 10.

35.

Isolating single cells in a neurosphere assay using inertial microfluidics.

Nathamgari SS, Dong B, Zhou F, Kang W, Giraldo-Vela JP, McGuire T, McNaughton RL, Sun C, Kessler JA, Espinosa HD.

Lab Chip. 2015 Dec 21;15(24):4591-7. doi: 10.1039/c5lc00805k. Epub 2015 Oct 29.

36.

Neurology--the next 10 years.

Baron R, Ferriero DM, Frisoni GB, Bettegowda C, Gokaslan ZL, Kessler JA, Vezzani A, Waxman SG, Jarius S, Wildemann B, Weller M.

Nat Rev Neurol. 2015 Nov;11(11):658-64. doi: 10.1038/nrneurol.2015.196. Epub 2015 Oct 27. Review.

37.

Role of adult hippocampal neurogenesis in persistent pain.

Apkarian AV, Mutso AA, Centeno MV, Kan L, Wu M, Levinstein M, Banisadr G, Gobeske KT, Miller RJ, Radulovic J, Hen R, Kessler JA.

Pain. 2016 Feb;157(2):418-28. doi: 10.1097/j.pain.0000000000000332.

38.

Astrocytic β1-integrin affects cellular composition of murine blood brain barrier in the cerebral cortex.

Venkatesan C, Birch D, Peng CY, Kessler JA.

Int J Dev Neurosci. 2015 Aug;44:48-54. doi: 10.1016/j.ijdevneu.2015.05.005. Epub 2015 May 19.

PMID:
25997909
39.

Double-blind, placebo-controlled study of HGF gene therapy in diabetic neuropathy.

Kessler JA, Smith AG, Cha BS, Choi SH, Wymer J, Shaibani A, Ajroud-Driss S, Vinik A; VM202 DPN-II Study Group.

Ann Clin Transl Neurol. 2015 May;2(5):465-78. doi: 10.1002/acn3.186. Epub 2015 Mar 5.

40.

miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma.

Kouri FM, Hurley LA, Daniel WL, Day ES, Hua Y, Hao L, Peng CY, Merkel TJ, Queisser MA, Ritner C, Zhang H, James CD, Sznajder JI, Chin L, Giljohann DA, Kessler JA, Peter ME, Mirkin CA, Stegh AH.

Genes Dev. 2015 Apr 1;29(7):732-45. doi: 10.1101/gad.257394.114.

41.

Human pluripotent stem cell-derived radial glia recapitulate developmental events and provide real-time access to cortical neurons and astrocytes.

Duan L, Peng CY, Pan L, Kessler JA.

Stem Cells Transl Med. 2015 May;4(5):437-47. doi: 10.5966/sctm.2014-0137. Epub 2015 Apr 1.

42.

β1-Integrin alters ependymal stem cell BMP receptor localization and attenuates astrogliosis after spinal cord injury.

North HA, Pan L, McGuire TL, Brooker S, Kessler JA.

J Neurosci. 2015 Mar 4;35(9):3725-33. doi: 10.1523/JNEUROSCI.4546-14.2015.

43.

Bioactive DNA-peptide nanotubes enhance the differentiation of neural stem cells into neurons.

Stephanopoulos N, Freeman R, North HA, Sur S, Jeong SJ, Tantakitti F, Kessler JA, Stupp SI.

Nano Lett. 2015 Jan 14;15(1):603-9. doi: 10.1021/nl504079q. Epub 2014 Dec 29.

44.

Ag(I) and Tl(I) precursors as transfer agents of a pyrrole-based pincer ligand to late transition metals.

Kessler JA, Iluc VM.

Inorg Chem. 2014 Dec 1;53(23):12360-71. doi: 10.1021/ic501600s. Epub 2014 Nov 11.

PMID:
25386700
45.

Microfluidic device for stem cell differentiation and localized electroporation of postmitotic neurons.

Kang W, Giraldo-Vela JP, Nathamgari SS, McGuire T, McNaughton RL, Kessler JA, Espinosa HD.

Lab Chip. 2014 Dec 7;14(23):4486-95. doi: 10.1039/c4lc00721b. Epub 2014 Sep 10.

46.

β1-Integrin and integrin linked kinase regulate astrocytic differentiation of neural stem cells.

Pan L, North HA, Sahni V, Jeong SJ, Mcguire TL, Berns EJ, Stupp SI, Kessler JA.

PLoS One. 2014 Aug 6;9(8):e104335. doi: 10.1371/journal.pone.0104335. eCollection 2014.

47.

EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis.

Feng H, Lopez GY, Kim CK, Alvarez A, Duncan CG, Nishikawa R, Nagane M, Su AJ, Auron PE, Hedberg ML, Wang L, Raizer JJ, Kessler JA, Parsa AT, Gao WQ, Kim SH, Minata M, Nakano I, Grandis JR, McLendon RE, Bigner DD, Lin HK, Furnari FB, Cavenee WK, Hu B, Yan H, Cheng SY.

J Clin Invest. 2014 Sep;124(9):3741-56. doi: 10.1172/JCI73093. Epub 2014 Jul 25.

48.

MicroRNAs participate in the murine oligodendroglial response to perinatal hypoxia-ischemia.

Birch D, Britt BC, Dukes SC, Kessler JA, Dizon ML.

Pediatr Res. 2014 Oct;76(4):334-40. doi: 10.1038/pr.2014.104. Epub 2014 Jul 8.

49.

Store-operated CRAC channels regulate gene expression and proliferation in neural progenitor cells.

Somasundaram A, Shum AK, McBride HJ, Kessler JA, Feske S, Miller RJ, Prakriya M.

J Neurosci. 2014 Jul 2;34(27):9107-23. doi: 10.1523/JNEUROSCI.0263-14.2014.

50.

Evaluation of the cellular origins of heterotopic ossification.

Kan L, Kessler JA.

Orthopedics. 2014 May;37(5):329-40. doi: 10.3928/01477447-20140430-07. Review.

PMID:
24810815

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