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Items: 1 to 50 of 527

1.

Genetically encoded Ca2+ -sensor reveals details of porcine endothelial cell activation upon contact with human serum.

Wuensch A, Kameritsch P, Sfriso R, Jemiller EM, Bähr A, Kurome M, Kessler B, Kemter E, Kupatt C, Reichart B, Rieben R, Wolf E, Klymiuk N.

Xenotransplantation. 2020 Feb 14:e12585. doi: 10.1111/xen.12585. [Epub ahead of print]

PMID:
32056300
2.

Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions.

Thézénas ML, De Leo B, Laux-Biehlmann A, Bafligil C, Elger B, Tapmeier T, Morten K, Rahmioglu N, Dakin SG, Charles P, Martinez FE, Steers G, Fischer OM, Mueller J, Hess-Stumpp H, Steinmeyer A, Manek S, Zondervan KT, Kennedy S, Becker CM, Shang C, Zollner TM, Kessler BM, Oppermann U.

Sci Rep. 2020 Jan 30;10(1):1495. doi: 10.1038/s41598-020-58362-3.

3.

Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy.

Moretti A, Fonteyne L, Giesert F, Hoppmann P, Meier AB, Bozoglu T, Baehr A, Schneider CM, Sinnecker D, Klett K, Fröhlich T, Rahman FA, Haufe T, Sun S, Jurisch V, Kessler B, Hinkel R, Dirschinger R, Martens E, Jilek C, Graf A, Krebs S, Santamaria G, Kurome M, Zakhartchenko V, Campbell B, Voelse K, Wolf A, Ziegler T, Reichert S, Lee S, Flenkenthaler F, Dorn T, Jeremias I, Blum H, Dendorfer A, Schnieke A, Krause S, Walter MC, Klymiuk N, Laugwitz KL, Wolf E, Wurst W, Kupatt C.

Nat Med. 2020 Feb;26(2):207-214. doi: 10.1038/s41591-019-0738-2. Epub 2020 Jan 27.

PMID:
31988462
4.

Authors' response.

Jonke G, Kessler B.

J Am Dent Assoc. 2020 Jan;151(1):6-7. doi: 10.1016/j.adaj.2019.11.011. No abstract available.

PMID:
31902401
5.

Quality of electronic records documenting adverse drug reactions within a hospital setting: identification of discrepancies and information completeness.

Braund R, Lawrence CK, Baum L, Kessler B, Vassart M, Coulter C.

N Z Med J. 2019 Jan 18;132(1488):28-37.

PMID:
31851659
6.

BMP signaling inhibition in Drosophila secondary cells remodels the seminal proteome and self and rival ejaculate functions.

Hopkins BR, Sepil I, Bonham S, Miller T, Charles PD, Fischer R, Kessler BM, Wilson C, Wigby S.

Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24719-24728. doi: 10.1073/pnas.1914491116. Epub 2019 Nov 18.

7.

Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.

Jansma M, Linke-Winnebeck C, Eustermann S, Lammens K, Kostrewa D, Stakyte K, Litz C, Kessler B, Hopfner KP.

Structure. 2020 Jan 7;28(1):83-95.e5. doi: 10.1016/j.str.2019.10.013. Epub 2019 Nov 15.

PMID:
31740028
8.

First Report on Ex Vivo Delivery of Paracrine Active Human Mesenchymal Stromal Cells to Liver Grafts During Machine Perfusion.

Verstegen MMA, Mezzanotte L, Ridwan RY, Wang K, de Haan J, Schurink IJ, Sierra Parraga JM, Hoogduijn M, Kessler BM, Huang H, Hall SRR, Ijzermans JNM, Löwik CWGM, van der Laan LJW, de Jonge J.

Transplantation. 2020 Jan;104(1):e5-e7. doi: 10.1097/TP.0000000000002986. No abstract available.

9.

Reducing the Reported Mortality Index Within a Neurocritical Care Unit Through Documentation and Coding Accuracy.

Kessler BA, Catalino MP, Jordan JD.

World Neurosurg. 2020 Jan;133:e819-e827. doi: 10.1016/j.wneu.2019.10.022. Epub 2019 Oct 10.

PMID:
31606500
10.

Viable pigs after simultaneous inactivation of porcine MHC class I and three xenoreactive antigen genes GGTA1, CMAH and B4GALNT2.

Fischer K, Rieblinger B, Hein R, Sfriso R, Zuber J, Fischer A, Klinger B, Liang W, Flisikowski K, Kurome M, Zakhartchenko V, Kessler B, Wolf E, Rieben R, Schwinzer R, Kind A, Schnieke A.

Xenotransplantation. 2020 Jan;27(1):e12560. doi: 10.1111/xen.12560. Epub 2019 Oct 8.

11.

Cost of prenatal versus postnatal myelomeningocele closure for both mother and child at 1 year of life.

Kessler BA, Catalino MP, Quinsey C, Goodnight W, Elton S.

Neurosurg Focus. 2019 Oct 1;47(4):E15. doi: 10.3171/2019.7.FOCUS19417.

PMID:
31574469
12.

Considerations for dental consultants.

Jonke G, Kessler B.

J Am Dent Assoc. 2019 Oct;150(10):890-892. doi: 10.1016/j.adaj.2019.07.018. No abstract available.

PMID:
31561763
13.

Comprehensive Landscape of Active Deubiquitinating Enzymes Profiled by Advanced Chemoproteomics.

Pinto-Fernández A, Davis S, Schofield AB, Scott HC, Zhang P, Salah E, Mathea S, Charles PD, Damianou A, Bond G, Fischer R, Kessler BM.

Front Chem. 2019 Aug 29;7:592. doi: 10.3389/fchem.2019.00592. eCollection 2019.

14.

Proteomics analysis of the matrisome from MC38 experimental mouse liver metastases.

Yuzhalin AE, Lim SY, Gordon-Weeks AN, Fischer R, Kessler BM, Yu D, Muschel RJ.

Am J Physiol Gastrointest Liver Physiol. 2019 Nov 1;317(5):G625-G639. doi: 10.1152/ajpgi.00014.2019. Epub 2019 Sep 23.

15.

Regulation of the endosomal SNX27-retromer by OTULIN.

Stangl A, Elliott PR, Pinto-Fernandez A, Bonham S, Harrison L, Schaub A, Kutzner K, Keusekotten K, Pfluger PT, El Oualid F, Kessler BM, Komander D, Krappmann D.

Nat Commun. 2019 Sep 20;10(1):4320. doi: 10.1038/s41467-019-12309-z.

16.

Letter to the Editor. External shunt valve after shunt removal for infection as a cost-saving measure.

Kessler BA, Elton S, Quinsey C.

J Neurosurg Pediatr. 2019 Sep 13:1-2. doi: 10.3171/2019.5.PEDS19296. [Epub ahead of print] No abstract available.

PMID:
31518972
17.

Mechanism of DNA End Sensing and Processing by the Mre11-Rad50 Complex.

Käshammer L, Saathoff JH, Lammens K, Gut F, Bartho J, Alt A, Kessler B, Hopfner KP.

Mol Cell. 2019 Nov 7;76(3):382-394.e6. doi: 10.1016/j.molcel.2019.07.035. Epub 2019 Sep 3.

PMID:
31492634
18.

Magnetic Particle Imaging meets Computed Tomography: first simultaneous imaging.

Vogel P, Markert J, Rückert MA, Herz S, Keßler B, Dremel K, Althoff D, Weber M, Buzug TM, Bley TA, Kullmann WH, Hanke R, Zabler S, Behr VC.

Sci Rep. 2019 Sep 2;9(1):12627. doi: 10.1038/s41598-019-48960-1.

19.

Composition and structure of synaptic ectosomes exporting antigen receptor linked to functional CD40 ligand from helper T cells.

Saliba DG, Céspedes-Donoso PF, Bálint Š, Compeer EB, Korobchevskaya K, Valvo S, Mayya V, Kvalvaag A, Peng Y, Dong T, Tognoli ML, O'Neill E, Bonham S, Fischer R, Kessler BM, Dustin ML.

Elife. 2019 Aug 30;8. pii: e47528. doi: 10.7554/eLife.47528.

20.

A Novel Role for Triglyceride Metabolism in Foxp3 Expression.

Howie D, Ten Bokum A, Cobbold SP, Yu Z, Kessler BM, Waldmann H.

Front Immunol. 2019 Aug 13;10:1860. doi: 10.3389/fimmu.2019.01860. eCollection 2019.

21.

Divergent allocation of sperm and the seminal proteome along a competition gradient in Drosophila melanogaster.

Hopkins BR, Sepil I, Thézénas ML, Craig JF, Miller T, Charles PD, Fischer R, Kessler BM, Bretman A, Pizzari T, Wigby S.

Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17925-17933. doi: 10.1073/pnas.1906149116. Epub 2019 Aug 20.

22.

E2F1 proteolysis via SCF-cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition.

Burdova K, Yang H, Faedda R, Hume S, Chauhan J, Ebner D, Kessler BM, Vendrell I, Drewry DH, Wells CI, Hatch SB, Dianov GL, Buffa FM, D'Angiolella V.

EMBO J. 2019 Oct 15;38(20):e101443. doi: 10.15252/embj.2018101443. Epub 2019 Aug 19.

23.

Ataxin-3 Links NOD2 and TLR2 Mediated Innate Immune Sensing and Metabolism in Myeloid Cells.

Chapman TP, Corridoni D, Shiraishi S, Pandey S, Aulicino A, Wigfield S, do Carmo Costa M, Thézénas ML, Paulson H, Fischer R, Kessler BM, Simmons A.

Front Immunol. 2019 Jul 19;10:1495. doi: 10.3389/fimmu.2019.01495. eCollection 2019.

24.

Transmission of Porcine Circovirus 3 (PCV3) by Xenotransplantation of Pig Hearts into Baboons.

Krüger L, Längin M, Reichart B, Fiebig U, Kristiansen Y, Prinz C, Kessler B, Egerer S, Wolf E, Abicht JM, Denner J.

Viruses. 2019 Jul 16;11(7). pii: E650. doi: 10.3390/v11070650.

25.

Mild maternal hyperglycemia in INS C93S transgenic pigs causes impaired glucose tolerance and metabolic alterations in neonatal offspring.

Renner S, Martins AS, Streckel E, Braun-Reichhart C, Backman M, Prehn C, Klymiuk N, Bähr A, Blutke A, Landbrecht-Schessl C, Wünsch A, Kessler B, Kurome M, Hinrichs A, Koopmans SJ, Krebs S, Kemter E, Rathkolb B, Nagashima H, Blum H, Ritzmann M, Wanke R, Aigner B, Adamski J, Hrabě de Angelis M, Wolf E.

Dis Model Mech. 2019 Aug 12;12(8). pii: dmm039156. doi: 10.1242/dmm.039156.

26.

Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation.

Bailey JD, Diotallevi M, Nicol T, McNeill E, Shaw A, Chuaiphichai S, Hale A, Starr A, Nandi M, Stylianou E, McShane H, Davis S, Fischer R, Kessler BM, McCullagh J, Channon KM, Crabtree MJ.

Cell Rep. 2019 Jul 2;28(1):218-230.e7. doi: 10.1016/j.celrep.2019.06.018.

27.

Molecular insights into an ancient form of Paget's disease of bone.

Shaw B, Burrell CL, Green D, Navarro-Martinez A, Scott D, Daroszewska A, van 't Hof R, Smith L, Hargrave F, Mistry S, Bottrill A, Kessler BM, Fischer R, Singh A, Dalmay T, Fraser WD, Henneberger K, King T, Gonzalez S, Layfield R.

Proc Natl Acad Sci U S A. 2019 May 21;116(21):10463-10472. doi: 10.1073/pnas.1820556116. Epub 2019 Apr 29.

28.

Capturing the dynamics of genome replication on individual ultra-long nanopore sequence reads.

Müller CA, Boemo MA, Spingardi P, Kessler BM, Kriaucionis S, Simpson JT, Nieduszynski CA.

Nat Methods. 2019 May;16(5):429-436. doi: 10.1038/s41592-019-0394-y. Epub 2019 Apr 22.

PMID:
31011185
29.

Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation.

Weiss-Sadan T, Itzhak G, Kaschani F, Yu Z, Mahameed M, Anaki A, Ben-Nun Y, Merquiol E, Tirosh B, Kessler B, Kaiser M, Blum G.

Mol Cell Proteomics. 2019 Jul;18(7):1330-1344. doi: 10.1074/mcp.RA119.001392. Epub 2019 Apr 22.

30.

Improved profiling of polyamines using two-dimensional gas chromatography mass spectrometry.

Yu Z, Huang H, Zhang H, Kessler BM.

Talanta. 2019 Jul 1;199:184-188. doi: 10.1016/j.talanta.2019.02.062. Epub 2019 Feb 18.

PMID:
30952244
31.

Author Correction: Consistent success in life-supporting porcine cardiac xenotransplantation.

Längin M, Mayr T, Reichart B, Michel S, Buchholz S, Guethoff S, Dashkevich A, Baehr A, Egerer S, Bauer A, Mihalj M, Panelli A, Issl L, Ying J, Fresch AK, Buttgereit I, Mokelke M, Radan J, Werner F, Lutzmann I, Steen S, Sjöberg T, Paskevicius A, Qiuming L, Sfriso R, Rieben R, Dahlhoff M, Kessler B, Kemter E, Kurome M, Zakhartchenko V, Klett K, Hinkel R, Kupatt C, Falkenau A, Reu S, Ellgass R, Herzog R, Binder U, Wich G, Skerra A, Ayares D, Kind A, Schönmann U, Kaup FJ, Hagl C, Wolf E, Klymiuk N, Brenner P, Abicht JM.

Nature. 2019 Apr;568(7752):E7. doi: 10.1038/s41586-019-1108-4.

PMID:
30944481
32.

USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7.

Sapmaz A, Berlin I, Bos E, Wijdeven RH, Janssen H, Konietzny R, Akkermans JJ, Erson-Bensan AE, Koning RI, Kessler BM, Neefjes J, Ovaa H.

Nat Commun. 2019 Mar 29;10(1):1454. doi: 10.1038/s41467-019-09437-x.

33.

MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.

Leimbacher PA, Jones SE, Shorrocks AK, de Marco Zompit M, Day M, Blaauwendraad J, Bundschuh D, Bonham S, Fischer R, Fink D, Kessler BM, Oliver AW, Pearl LH, Blackford AN, Stucki M.

Mol Cell. 2019 May 2;74(3):571-583.e8. doi: 10.1016/j.molcel.2019.02.014. Epub 2019 Mar 18.

34.

Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.

Valli A, Morotti M, Zois CE, Albers PK, Soga T, Feldinger K, Fischer R, Frejno M, McIntyre A, Bridges E, Haider S, Buffa FM, Baban D, Rodriguez M, Yanes O, Whittington HJ, Lake HA, Zervou S, Lygate CA, Kessler BM, Harris AL.

Mol Cancer Res. 2019 Jul;17(7):1531-1544. doi: 10.1158/1541-7786.MCR-18-0315. Epub 2019 Mar 18.

PMID:
30885992
35.

From herbal small RNAs to one medicine.

Ji C, Kriaucionis S, Kessler BM, Jiang C.

Sci China Life Sci. 2019 Mar;62(3):285-287. doi: 10.1007/s11427-019-9513-y. Epub 2019 Mar 1. No abstract available.

PMID:
30863963
36.

Development of context-sensitive pronunciation in reading: The case of ‹c› and ‹g›.

Treiman R, Kessler B.

J Exp Child Psychol. 2019 Jun;182:114-125. doi: 10.1016/j.jecp.2019.02.001. Epub 2019 Feb 25.

PMID:
30818226
37.

Colonic epithelial cell diversity in health and inflammatory bowel disease.

Parikh K, Antanaviciute A, Fawkner-Corbett D, Jagielowicz M, Aulicino A, Lagerholm C, Davis S, Kinchen J, Chen HH, Alham NK, Ashley N, Johnson E, Hublitz P, Bao L, Lukomska J, Andev RS, Björklund E, Kessler BM, Fischer R, Goldin R, Koohy H, Simmons A.

Nature. 2019 Mar;567(7746):49-55. doi: 10.1038/s41586-019-0992-y. Epub 2019 Feb 27.

38.

What Methods of Scoring Young Children's Spelling Best Predict Later Spelling Performance?

Treiman R, Caravolas M, Kessler B.

J Res Read. 2019 Feb;42(1):80-96. doi: 10.1111/1467-9817.12241. Epub 2018 May 11.

39.

Deacetylation Inhibition Reverses PABPN1-Dependent Muscle Wasting.

Olie CS, Riaz M, Konietzny R, Charles PD, Pinto-Fernandez A, Kiełbasa SM, Aartsma-Rus A, Goeman JJ, Kessler BM, Raz V.

iScience. 2019 Feb 22;12:318-332. doi: 10.1016/j.isci.2019.01.024. Epub 2019 Jan 22.

40.

Integrated Physiological and Biochemical Assessments for the Prediction of Growth of Abdominal Aortic Aneurysms in Humans.

Lee R, Charles PD, Lapolla P, Cassimjee I, Huang H, Kessler B, Fischer R, Handa A; Oxford Abdominal Aortic Aneurysm Study, the Oxford Regional Vascular Services.

Ann Surg. 2019 Jul;270(1):e1-e3. doi: 10.1097/SLA.0000000000003154. No abstract available.

PMID:
30601258
41.

Human Platelet Protein Ubiquitylation and Changes following GPVI Activation.

Unsworth AJ, Bombik I, Pinto-Fernandez A, McGouran JF, Konietzny R, Zahedi RP, Watson SP, Kessler BM, Pears CJ.

Thromb Haemost. 2019 Jan;119(1):104-116. doi: 10.1055/s-0038-1676344. Epub 2018 Dec 31.

42.

An Activity-Based Probe Targeting Non-Catalytic, Highly Conserved Amino Acid Residues within Bromodomains.

D'Ascenzio M, Pugh KM, Konietzny R, Berridge G, Tallant C, Hashem S, Monteiro O, Thomas JR, Schirle M, Knapp S, Marsden B, Fedorov O, Bountra C, Kessler BM, Brennan PE.

Angew Chem Int Ed Engl. 2019 Jan 21;58(4):1007-1012. doi: 10.1002/anie.201807825. Epub 2018 Dec 27.

43.

The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis.

Volkmar N, Thezenas ML, Louie SM, Juszkiewicz S, Nomura DK, Hegde RS, Kessler BM, Christianson JC.

J Cell Sci. 2019 Jan 16;132(2). pii: jcs223453. doi: 10.1242/jcs.223453.

44.

The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage.

Nishi R, Wijnhoven PWG, Kimura Y, Matsui M, Konietzny R, Wu Q, Nakamura K, Blundell TL, Kessler BM.

Sci Rep. 2018 Dec 17;8(1):17891. doi: 10.1038/s41598-018-36235-0.

45.

Resistance to Src inhibition alters the BRAF-mutant tumor secretome to promote an invasive phenotype and therapeutic escape through a FAK>p130Cas>c-Jun signaling axis.

Kessler BE, Mishall KM, Kellett MD, Clark EG, Pugazhenthi U, Pozdeyev N, Kim J, Tan AC, Schweppe RE.

Oncogene. 2019 Apr;38(14):2565-2579. doi: 10.1038/s41388-018-0617-1. Epub 2018 Dec 10.

46.

Consistent success in life-supporting porcine cardiac xenotransplantation.

Längin M, Mayr T, Reichart B, Michel S, Buchholz S, Guethoff S, Dashkevich A, Baehr A, Egerer S, Bauer A, Mihalj M, Panelli A, Issl L, Ying J, Fresch AK, Buttgereit I, Mokelke M, Radan J, Werner F, Lutzmann I, Steen S, Sjöberg T, Paskevicius A, Qiuming L, Sfriso R, Rieben R, Dahlhoff M, Kessler B, Kemter E, Kurome M, Zakhartchenko V, Klett K, Hinkel R, Kupatt C, Falkenau A, Reu S, Ellgass R, Herzog R, Binder U, Wich G, Skerra A, Ayares D, Kind A, Schönmann U, Kaup FJ, Hagl C, Wolf E, Klymiuk N, Brenner P, Abicht JM.

Nature. 2018 Dec;564(7736):430-433. doi: 10.1038/s41586-018-0765-z. Epub 2018 Dec 5. Erratum in: Nature. 2019 Apr;568(7752):E7.

PMID:
30518863
47.

Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.

Vazquez-Rodriguez S, Wright M, Rogers CM, Cribbs AP, Velupillai S, Philpott M, Lee H, Dunford JE, Huber KVM, Robers MB, Vasta JD, Thezenas ML, Bonham S, Kessler B, Bennett J, Fedorov O, Raynaud F, Donovan A, Blagg J, Bavetsias V, Oppermann U, Bountra C, Kawamura A, Brennan PE.

Angew Chem Int Ed Engl. 2019 Jan 8;58(2):515-519. doi: 10.1002/anie.201810179. Epub 2018 Dec 7.

48.

Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix.

Yuzhalin AE, Gordon-Weeks AN, Tognoli ML, Jones K, Markelc B, Konietzny R, Fischer R, Muth A, O'Neill E, Thompson PR, Venables PJ, Kessler BM, Lim SY, Muschel RJ.

Nat Commun. 2018 Nov 14;9(1):4783. doi: 10.1038/s41467-018-07306-7.

49.

UFLC-Derived CSF Extracellular Vesicle Origin and Proteome.

Thompson AG, Gray E, Mager I, Fischer R, Thézénas ML, Charles PD, Talbot K, El Andaloussi S, Kessler BM, Wood M, Turner MR.

Proteomics. 2018 Dec;18(24):e1800257. doi: 10.1002/pmic.201800257. Epub 2018 Dec 10.

PMID:
30411858
50.

Targeting αGal epitopes for multi-species embryo immunosurgery.

Kurome M, Baehr A, Simmet K, Jemiller EM, Egerer S, Dahlhoff M, Zakhartchenko V, Nagashima H, Klymiuk N, Kessler B, Wolf E.

Reprod Fertil Dev. 2019 Apr;31(4):820-826. doi: 10.1071/RD18120.

PMID:
30384878

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