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Items: 1 to 50 of 505

1.

Ataxin-3 Links NOD2 and TLR2 Mediated Innate Immune Sensing and Metabolism in Myeloid Cells.

Chapman TP, Corridoni D, Shiraishi S, Pandey S, Aulicino A, Wigfield S, do Carmo Costa M, Thézénas ML, Paulson H, Fischer R, Kessler BM, Simmons A.

Front Immunol. 2019 Jul 19;10:1495. doi: 10.3389/fimmu.2019.01495. eCollection 2019.

2.

Transmission of Porcine Circovirus 3 (PCV3) by Xenotransplantation of Pig Hearts into Baboons.

Krüger L, Längin M, Reichart B, Fiebig U, Kristiansen Y, Prinz C, Kessler B, Egerer S, Wolf E, Abicht JM, Denner J.

Viruses. 2019 Jul 16;11(7). pii: E650. doi: 10.3390/v11070650.

3.

Mild maternal hyperglycemia in INS C93S transgenic pigs causes impaired glucose tolerance and metabolic alterations in neonatal offspring.

Renner S, Martins AS, Streckel E, Braun-Reichhart C, Backman M, Prehn C, Klymiuk N, Bähr A, Blutke A, Landbrecht-Schessl C, Wünsch A, Kessler B, Kurome M, Hinrichs A, Koopmans SJ, Krebs S, Kemter E, Rathkolb B, Nagashima H, Blum H, Ritzmann M, Wanke R, Aigner B, Adamski J, Hrabě de Angelis M, Wolf E.

Dis Model Mech. 2019 Aug 12;12(8). pii: dmm039156. doi: 10.1242/dmm.039156.

4.

Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation.

Bailey JD, Diotallevi M, Nicol T, McNeill E, Shaw A, Chuaiphichai S, Hale A, Starr A, Nandi M, Stylianou E, McShane H, Davis S, Fischer R, Kessler BM, McCullagh J, Channon KM, Crabtree MJ.

Cell Rep. 2019 Jul 2;28(1):218-230.e7. doi: 10.1016/j.celrep.2019.06.018.

5.

Molecular insights into an ancient form of Paget's disease of bone.

Shaw B, Burrell CL, Green D, Navarro-Martinez A, Scott D, Daroszewska A, van 't Hof R, Smith L, Hargrave F, Mistry S, Bottrill A, Kessler BM, Fischer R, Singh A, Dalmay T, Fraser WD, Henneberger K, King T, Gonzalez S, Layfield R.

Proc Natl Acad Sci U S A. 2019 May 21;116(21):10463-10472. doi: 10.1073/pnas.1820556116. Epub 2019 Apr 29.

6.

Capturing the dynamics of genome replication on individual ultra-long nanopore sequence reads.

Müller CA, Boemo MA, Spingardi P, Kessler BM, Kriaucionis S, Simpson JT, Nieduszynski CA.

Nat Methods. 2019 May;16(5):429-436. doi: 10.1038/s41592-019-0394-y. Epub 2019 Apr 22.

PMID:
31011185
7.

Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation.

Weiss-Sadan T, Itzhak G, Kaschani F, Yu Z, Mahameed M, Anaki A, Ben-Nun Y, Merquiol E, Tirosh B, Kessler B, Kaiser M, Blum G.

Mol Cell Proteomics. 2019 Jul;18(7):1330-1344. doi: 10.1074/mcp.RA119.001392. Epub 2019 Apr 22.

8.

Improved profiling of polyamines using two-dimensional gas chromatography mass spectrometry.

Yu Z, Huang H, Zhang H, Kessler BM.

Talanta. 2019 Jul 1;199:184-188. doi: 10.1016/j.talanta.2019.02.062. Epub 2019 Feb 18.

PMID:
30952244
9.

Author Correction: Consistent success in life-supporting porcine cardiac xenotransplantation.

Längin M, Mayr T, Reichart B, Michel S, Buchholz S, Guethoff S, Dashkevich A, Baehr A, Egerer S, Bauer A, Mihalj M, Panelli A, Issl L, Ying J, Fresch AK, Buttgereit I, Mokelke M, Radan J, Werner F, Lutzmann I, Steen S, Sjöberg T, Paskevicius A, Qiuming L, Sfriso R, Rieben R, Dahlhoff M, Kessler B, Kemter E, Kurome M, Zakhartchenko V, Klett K, Hinkel R, Kupatt C, Falkenau A, Reu S, Ellgass R, Herzog R, Binder U, Wich G, Skerra A, Ayares D, Kind A, Schönmann U, Kaup FJ, Hagl C, Wolf E, Klymiuk N, Brenner P, Abicht JM.

Nature. 2019 Apr;568(7752):E7. doi: 10.1038/s41586-019-1108-4.

PMID:
30944481
10.

USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7.

Sapmaz A, Berlin I, Bos E, Wijdeven RH, Janssen H, Konietzny R, Akkermans JJ, Erson-Bensan AE, Koning RI, Kessler BM, Neefjes J, Ovaa H.

Nat Commun. 2019 Mar 29;10(1):1454. doi: 10.1038/s41467-019-09437-x.

11.

MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis.

Leimbacher PA, Jones SE, Shorrocks AK, de Marco Zompit M, Day M, Blaauwendraad J, Bundschuh D, Bonham S, Fischer R, Fink D, Kessler BM, Oliver AW, Pearl LH, Blackford AN, Stucki M.

Mol Cell. 2019 May 2;74(3):571-583.e8. doi: 10.1016/j.molcel.2019.02.014. Epub 2019 Mar 18.

12.

Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.

Valli A, Morotti M, Zois CE, Albers PK, Soga T, Feldinger K, Fischer R, Frejno M, McIntyre A, Bridges E, Haider S, Buffa FM, Baban D, Rodriguez M, Yanes O, Whittington HJ, Lake HA, Zervou S, Lygate CA, Kessler BM, Harris AL.

Mol Cancer Res. 2019 Jul;17(7):1531-1544. doi: 10.1158/1541-7786.MCR-18-0315. Epub 2019 Mar 18.

PMID:
30885992
13.

From herbal small RNAs to one medicine.

Ji C, Kriaucionis S, Kessler BM, Jiang C.

Sci China Life Sci. 2019 Mar;62(3):285-287. doi: 10.1007/s11427-019-9513-y. Epub 2019 Mar 1. No abstract available.

PMID:
30863963
14.

Development of context-sensitive pronunciation in reading: The case of ‹c› and ‹g›.

Treiman R, Kessler B.

J Exp Child Psychol. 2019 Jun;182:114-125. doi: 10.1016/j.jecp.2019.02.001. Epub 2019 Feb 25.

PMID:
30818226
15.

Colonic epithelial cell diversity in health and inflammatory bowel disease.

Parikh K, Antanaviciute A, Fawkner-Corbett D, Jagielowicz M, Aulicino A, Lagerholm C, Davis S, Kinchen J, Chen HH, Alham NK, Ashley N, Johnson E, Hublitz P, Bao L, Lukomska J, Andev RS, Björklund E, Kessler BM, Fischer R, Goldin R, Koohy H, Simmons A.

Nature. 2019 Mar;567(7746):49-55. doi: 10.1038/s41586-019-0992-y. Epub 2019 Feb 27.

PMID:
30814735
16.

What Methods of Scoring Young Children's Spelling Best Predict Later Spelling Performance?

Treiman R, Caravolas M, Kessler B.

J Res Read. 2019 Feb;42(1):80-96. doi: 10.1111/1467-9817.12241. Epub 2018 May 11.

PMID:
30739964
17.

Deacetylation Inhibition Reverses PABPN1-Dependent Muscle Wasting.

Olie CS, Riaz M, Konietzny R, Charles PD, Pinto-Fernandez A, Kiełbasa SM, Aartsma-Rus A, Goeman JJ, Kessler BM, Raz V.

iScience. 2019 Feb 22;12:318-332. doi: 10.1016/j.isci.2019.01.024. Epub 2019 Jan 22.

18.

Integrated Physiological and Biochemical Assessments for the Prediction of Growth of Abdominal Aortic Aneurysms in Humans.

Lee R, Charles PD, Lapolla P, Cassimjee I, Huang H, Kessler B, Fischer R, Handa A; Oxford Abdominal Aortic Aneurysm Study, the Oxford Regional Vascular Services.

Ann Surg. 2019 Jul;270(1):e1-e3. doi: 10.1097/SLA.0000000000003154. No abstract available.

PMID:
30601258
19.

Human Platelet Protein Ubiquitylation and Changes following GPVI Activation.

Unsworth AJ, Bombik I, Pinto-Fernandez A, McGouran JF, Konietzny R, Zahedi RP, Watson SP, Kessler BM, Pears CJ.

Thromb Haemost. 2019 Jan;119(1):104-116. doi: 10.1055/s-0038-1676344. Epub 2018 Dec 31.

20.

An Activity-Based Probe Targeting Non-Catalytic, Highly Conserved Amino Acid Residues within Bromodomains.

D'Ascenzio M, Pugh KM, Konietzny R, Berridge G, Tallant C, Hashem S, Monteiro O, Thomas JR, Schirle M, Knapp S, Marsden B, Fedorov O, Bountra C, Kessler BM, Brennan PE.

Angew Chem Int Ed Engl. 2019 Jan 21;58(4):1007-1012. doi: 10.1002/anie.201807825. Epub 2018 Dec 27.

21.

The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis.

Volkmar N, Thezenas ML, Louie SM, Juszkiewicz S, Nomura DK, Hegde RS, Kessler BM, Christianson JC.

J Cell Sci. 2019 Jan 16;132(2). pii: jcs223453. doi: 10.1242/jcs.223453.

22.

The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage.

Nishi R, Wijnhoven PWG, Kimura Y, Matsui M, Konietzny R, Wu Q, Nakamura K, Blundell TL, Kessler BM.

Sci Rep. 2018 Dec 17;8(1):17891. doi: 10.1038/s41598-018-36235-0.

23.

Resistance to Src inhibition alters the BRAF-mutant tumor secretome to promote an invasive phenotype and therapeutic escape through a FAK>p130Cas>c-Jun signaling axis.

Kessler BE, Mishall KM, Kellett MD, Clark EG, Pugazhenthi U, Pozdeyev N, Kim J, Tan AC, Schweppe RE.

Oncogene. 2019 Apr;38(14):2565-2579. doi: 10.1038/s41388-018-0617-1. Epub 2018 Dec 10.

24.

Consistent success in life-supporting porcine cardiac xenotransplantation.

Längin M, Mayr T, Reichart B, Michel S, Buchholz S, Guethoff S, Dashkevich A, Baehr A, Egerer S, Bauer A, Mihalj M, Panelli A, Issl L, Ying J, Fresch AK, Buttgereit I, Mokelke M, Radan J, Werner F, Lutzmann I, Steen S, Sjöberg T, Paskevicius A, Qiuming L, Sfriso R, Rieben R, Dahlhoff M, Kessler B, Kemter E, Kurome M, Zakhartchenko V, Klett K, Hinkel R, Kupatt C, Falkenau A, Reu S, Ellgass R, Herzog R, Binder U, Wich G, Skerra A, Ayares D, Kind A, Schönmann U, Kaup FJ, Hagl C, Wolf E, Klymiuk N, Brenner P, Abicht JM.

Nature. 2018 Dec;564(7736):430-433. doi: 10.1038/s41586-018-0765-z. Epub 2018 Dec 5. Erratum in: Nature. 2019 Apr;568(7752):E7.

PMID:
30518863
25.

Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.

Vazquez-Rodriguez S, Wright M, Rogers CM, Cribbs AP, Velupillai S, Philpott M, Lee H, Dunford JE, Huber KVM, Robers MB, Vasta JD, Thezenas ML, Bonham S, Kessler B, Bennett J, Fedorov O, Raynaud F, Donovan A, Blagg J, Bavetsias V, Oppermann U, Bountra C, Kawamura A, Brennan PE.

Angew Chem Int Ed Engl. 2019 Jan 8;58(2):515-519. doi: 10.1002/anie.201810179. Epub 2018 Dec 7.

26.

Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix.

Yuzhalin AE, Gordon-Weeks AN, Tognoli ML, Jones K, Markelc B, Konietzny R, Fischer R, Muth A, O'Neill E, Thompson PR, Venables PJ, Kessler BM, Lim SY, Muschel RJ.

Nat Commun. 2018 Nov 14;9(1):4783. doi: 10.1038/s41467-018-07306-7.

27.

UFLC-Derived CSF Extracellular Vesicle Origin and Proteome.

Thompson AG, Gray E, Mager I, Fischer R, Thézénas ML, Charles PD, Talbot K, El Andaloussi S, Kessler BM, Wood M, Turner MR.

Proteomics. 2018 Dec;18(24):e1800257. doi: 10.1002/pmic.201800257. Epub 2018 Dec 10.

PMID:
30411858
28.

Targeting αGal epitopes for multi-species embryo immunosurgery.

Kurome M, Baehr A, Simmet K, Jemiller EM, Egerer S, Dahlhoff M, Zakhartchenko V, Nagashima H, Klymiuk N, Kessler B, Wolf E.

Reprod Fertil Dev. 2019 Apr;31(4):820-826. doi: 10.1071/RD18120.

PMID:
30384878
29.

Hip and Knee Section, Treatment, Antimicrobials: Proceedings of International Consensus on Orthopedic Infections.

de Beaubien B, Belden K, Bell K, Boyle KK, Cordero-Ampuero J, Della Valle CJ, Eijer H, Ferry C, Janz V, Kessler B, Kratky A, Lachiewicz A, Martin KE, Murillo O, Nijhof M, Nodzo SR, Petrie MJ, Stockley I, Suleiman LI.

J Arthroplasty. 2019 Feb;34(2S):S477-S482. doi: 10.1016/j.arth.2018.09.033. Epub 2018 Oct 19. No abstract available.

PMID:
30348565
30.

Identification of UHRF2 as a novel DNA interstrand crosslink sensor protein.

Motnenko A, Liang CC, Yang D, Lopez-Martinez D, Yoshikawa Y, Zhan B, Ward KE, Tian J, Haas W, Spingardi P, Kessler BM, Kriaucionis S, Gygi SP, Cohn MA.

PLoS Genet. 2018 Oct 18;14(10):e1007643. doi: 10.1371/journal.pgen.1007643. eCollection 2018 Oct.

31.

Quantitative Proteomics Identification of Seminal Fluid Proteins in Male Drosophila melanogaster.

Sepil I, Hopkins BR, Dean R, Thézénas ML, Charles PD, Konietzny R, Fischer R, Kessler BM, Wigby S.

Mol Cell Proteomics. 2019 Mar 15;18(Suppl 1):S46-S58. doi: 10.1074/mcp.RA118.000831. Epub 2018 Oct 4.

32.

Early weaning completely eliminates porcine cytomegalovirus from a newly established pig donor facility for xenotransplantation.

Egerer S, Fiebig U, Kessler B, Zakhartchenko V, Kurome M, Reichart B, Kupatt C, Klymiuk N, Wolf E, Denner J, Bähr A.

Xenotransplantation. 2018 Jul;25(4):e12449. doi: 10.1111/xen.12449.

PMID:
30264883
33.

β-TrCP- and Casein Kinase II-Mediated Degradation of Cyclin F Controls Timely Mitotic Progression.

Mavrommati I, Faedda R, Galasso G, Li J, Burdova K, Fischer R, Kessler BM, Carrero ZI, Guardavaccaro D, Pagano M, D'Angiolella V.

Cell Rep. 2018 Sep 25;24(13):3404-3412. doi: 10.1016/j.celrep.2018.08.076.

34.

Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation.

Bailey J, Davis S, Shaw A, Diotallevi M, Fischer R, Benson MA, Zhu H, Brown J, Bhattacharya S, Kessler BM, Channon KM, Crabtree MJ.

Sci Rep. 2018 Sep 25;8(1):14310. doi: 10.1038/s41598-018-32481-4.

35.

Proteomic profiling of the plasma of Gambian children with cerebral malaria.

Moussa EM, Huang H, Thézénas ML, Fischer R, Ramaprasad A, Sisay-Joof F, Jallow M, Pain A, Kwiatkowski D, Kessler BM, Casals-Pascual C.

Malar J. 2018 Sep 24;17(1):337. doi: 10.1186/s12936-018-2487-y.

36.

A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes.

Zhang T, Wei G, Millard CJ, Fischer R, Konietzny R, Kessler BM, Schwabe JWR, Brockdorff N.

Nat Commun. 2018 Sep 18;9(1):3798. doi: 10.1038/s41467-018-06235-9.

37.

Statistical learning and spelling: Evidence from Brazilian prephonological spellers.

Treiman R, Cardoso-Martins C, Pollo TC, Kessler B.

Cognition. 2019 Jan;182:1-7. doi: 10.1016/j.cognition.2018.08.016. Epub 2018 Sep 7.

PMID:
30199757
38.

Subclinical Changes in Deceased Donor Kidney Proteomes Are Associated With 12-month Allograft Function Posttransplantation-A Preliminary Study.

Kaisar M, van Dullemen L, Charles P, Akhtar ZM, Thézénas ML, Huang H, Klooster A, Watkins NA, Kessler B, Ploeg RJ.

Transplantation. 2019 Feb;103(2):323-328. doi: 10.1097/TP.0000000000002358.

39.

53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ.

Ghezraoui H, Oliveira C, Becker JR, Bilham K, Moralli D, Anzilotti C, Fischer R, Deobagkar-Lele M, Sanchiz-Calvo M, Fueyo-Marcos E, Bonham S, Kessler BM, Rottenberg S, Cornall RJ, Green CM, Chapman JR.

Nature. 2018 Aug;560(7716):122-127. doi: 10.1038/s41586-018-0362-1. Epub 2018 Jul 25.

PMID:
30046110
40.

Glutamate receptor δ2 serum antibodies in pediatric opsoclonus myoclonus ataxia syndrome.

Berridge G, Menassa DA, Moloney T, Waters PJ, Welding I, Thomsen S, Zuberi S, Fischer R, Aricescu AR, Pike M, Dale RC, Kessler B, Vincent A, Lim M, Irani SR, Lang B.

Neurology. 2018 Aug 21;91(8):e714-e723. doi: 10.1212/WNL.0000000000006035. Epub 2018 Jul 25.

41.

Publisher Correction: The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases.

Markolovic S, Zhuang Q, Wilkins SE, Eaton CD, Abboud MI, Katz MJ, McNeil HE, Leśniak RK, Hall C, Struwe WB, Konietzny R, Davis S, Yang M, Ge W, Benesch JLP, Kessler BM, Ratcliffe PJ, Cockman ME, Fischer R, Wappner P, Chowdhury R, Coleman ML, Schofield CJ.

Nat Chem Biol. 2018 Oct;14(10):988. doi: 10.1038/s41589-018-0104-6.

PMID:
29950663
42.

The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases.

Markolovic S, Zhuang Q, Wilkins SE, Eaton CD, Abboud MI, Katz MJ, McNeil HE, Leśniak RK, Hall C, Struwe WB, Konietzny R, Davis S, Yang M, Ge W, Benesch JLP, Kessler BM, Ratcliffe PJ, Cockman ME, Fischer R, Wappner P, Chowdhury R, Coleman ML, Schofield CJ.

Nat Chem Biol. 2018 Jul;14(7):688-695. doi: 10.1038/s41589-018-0071-y. Epub 2018 Jun 18. Erratum in: Nat Chem Biol. 2018 Jun 27;:.

43.

Development and validation of response markers to predict survival and pleurodesis success in patients with malignant pleural effusion (PROMISE): a multicohort analysis.

Psallidas I, Kanellakis NI, Gerry S, Thézénas ML, Charles PD, Samsonova A, Schiller HB, Fischer R, Asciak R, Hallifax RJ, Mercer R, Dobson M, Dong T, Pavord ID, Collins GS, Kessler BM, Pass HI, Maskell N, Stathopoulos GT, Rahman NM.

Lancet Oncol. 2018 Jul;19(7):930-939. doi: 10.1016/S1470-2045(18)30294-8. Epub 2018 Jun 13.

PMID:
29908990
44.

Proteo-metabolomics reveals compensation between ischemic and non-injured contralateral kidneys after reperfusion.

Huang H, van Dullemen LFA, Akhtar MZ, Faro ML, Yu Z, Valli A, Dona A, Thézénas ML, Charles PD, Fischer R, Kaisar M, Leuvenink HGD, Ploeg RJ, Kessler BM.

Sci Rep. 2018 Jun 4;8(1):8539. doi: 10.1038/s41598-018-26804-8.

45.

Hand Compartment Syndrome Due to N-acetylcysteine Extravasation.

Thoppil J, Berman A, Kessler B, Sud P, Nogar J.

Clin Pract Cases Emerg Med. 2017 Oct 18;1(4):377-379. doi: 10.5811/cpcem.2017.9.35152. eCollection 2017 Nov.

46.

FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment.

Dimitrova E, Kondo T, Feldmann A, Nakayama M, Koseki Y, Konietzny R, Kessler BM, Koseki H, Klose RJ.

Elife. 2018 May 29;7. pii: e37084. doi: 10.7554/eLife.37084.

47.

Immunopeptidomic Profiling of HLA-A2-Positive Triple Negative Breast Cancer Identifies Potential Immunotherapy Target Antigens.

Ternette N, Olde Nordkamp MJM, Müller J, Anderson AP, Nicastri A, Hill AVS, Kessler BM, Li D.

Proteomics. 2018 Jun;18(12):e1700465. doi: 10.1002/pmic.201700465.

48.

Discrimination Between Human Leukocyte Antigen Class I-Bound and Co-Purified HIV-Derived Peptides in Immunopeptidomics Workflows.

Partridge T, Nicastri A, Kliszczak AE, Yindom LM, Kessler BM, Ternette N, Borrow P.

Front Immunol. 2018 Apr 27;9:912. doi: 10.3389/fimmu.2018.00912. eCollection 2018.

49.

Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver.

Hinrichs A, Kessler B, Kurome M, Blutke A, Kemter E, Bernau M, Scholz AM, Rathkolb B, Renner S, Bultmann S, Leonhardt H, de Angelis MH, Nagashima H, Hoeflich A, Blum WF, Bidlingmaier M, Wanke R, Dahlhoff M, Wolf E.

Mol Metab. 2018 May;11:113-128. doi: 10.1016/j.molmet.2018.03.006. Epub 2018 Mar 15.

50.

Immune Control of Burkholderia pseudomallei--Common, High-Frequency T-Cell Responses to a Broad Repertoire of Immunoprevalent Epitopes.

Nithichanon A, Rinchai D, Buddhisa S, Saenmuang P, Kewcharoenwong C, Kessler B, Khaenam P, Chetchotisakd P, Maillere B, Robinson J, Reynolds CJ, Boyton RJ, Altmann DM, Lertmemongkolchai G.

Front Immunol. 2018 Mar 20;9:484. doi: 10.3389/fimmu.2018.00484. eCollection 2018.

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